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INDONESIA
BIOEDUSCIENCE
Published by Universitas Muhammadiyah Prof. Dr. Hamka
ISSN : 2614154X     EISSN : 26141558     DOI : -
Core Subject : Science, Education, Agriculture,
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Education
BIOEDUSCIENCE is an open access journal that publishes research in the field of Biology and Biosain Education such as: Applied and implemented in education and learning, Botany, Zoology, Microbiology, Ecology, Biotechnology, Molecular Biology, Genetics, Bioinformatics, Cell and Developmental Biology, Biodiversity and Bioconservation. BIOEDUSCIENCE is published by Biology Education Study Program, Universitas Muhammadiyah Prof. Dr. Hamka, Indonesia regularly in June and December. ISSN : 2614-1558; P-ISSN : 2614-154X.
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Articles 544 Documents
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Producing Lactobacillus plantarum Dry Starter using Rice Bran Matrix Nurhasna, Aprilia; Meryandini, Anja; Candra Sunarti , Titi
BIOEDUSCIENCE Vol 7 No 3 (2023): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/jbes/10654

Abstract

Background: Lactic Acid Bacteria (LAB) starter is an instant LAB culture that has been prepared to initiate lactic acid production in the fermentation process. The manufacture of BAL starter requires alternative media as a substitute for MRS media which costs a lot when used for industrial production. To protect cells, an encapsulant matrix is needed which functions to provide insulation for bacterial cells against the drying process which can damage cells and a good media is needed and is capable of being an encapsulation matrix in the manufacture of dry LAB starter. Lactobacillus plantarum NHC6 bacteria is a lactic acid bacteria that has the potential to be developed. Method: making encapsulation matrix using rice bran. The bran media consisted of 10% (w/v) rice bran added with 5% (w/v) glucose and 1% (w/v) ammonium sulfate. As much as 10% (w/v) of L. plantarum NHC6 culture which was in the late log phase was inoculated in bran media. The liquid starter was then incubated again for 14 hours at 37°C. After that, the drying process was carried out using a spray dryer at an inlet temperature of 170°C. Result: The number of live cells in the bran starter decreased after the spray drying process. Starter storage at 28°C and 4°C has a significantly different effect. Conclusion: Rice bran matrix is capable of being an encapsulating agent and is able to protect L. plantarum NHC6 cells from high temperatures during the spray drying method in the manufacture of dry starter.
Studi Pengaruh Iradiasi Gamma Terhadap Kadar Senyawa Bioaktif dan Aktivitas Antiinflamasi Jahe Merah (Zingiber officinale roscoe) Aulia Nova Kusumaningtyas; Yahdiana Harahap; Abdul Mun'im; Supandi Supandi
BIOEDUSCIENCE Vol 6 No 3 (2022): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/jbes/6310688

Abstract

Background: In Indonesia, the use of herbal plants in overcoming several health problems shows a fairly high rate. Red ginger is one of the herbs that is widely consumed and empirically has the property of relieving or reducing inflammation. However, as is well known, in general the microbiological contamination of herbs is quite high. To maintain the quality of herbal plants, special treatment is required, to ensure that microbial contamination is within safe limits. This study aims to determine the effect of gamma irradiation on the number of microbial contamination, and the bioactive content of 6,8,10-gingerol; 6-shogaol in 70% ethanol extract of red ginger, and its activity as an anti-inflammatory. Methodes: Samples of 70% ethanol extract of red ginger were irradiated with various doses of 0, 5, 7.5, 10 and 15 KGy. Microbiological contamination is determined in Total Plate Number and Yeast Mold Number. The content of compounds 6,8,10-gingerol and 6-shogaol was observed by high performance liquid method and their anti-inflammatory activity was observed by protein denaturation inhibition (BSA) method. Results: Gamma irradiation at doses of 0, 5, 7.5, 10 and 15 KGy reduced microbial contamination as the exposure dose increased, and did not affect the levels of bioactive 6,8,10-gingerol; 6-shogaol and its anti-inflammatory activity. The anti-inflammatory activity of 70% ethanol extract of red ginger is influenced by the content of bioactive compounds. Conclusion: Gamma irradiation is effective for decontaminating microbiological contaminants, and improving the quality of red ginger, and does not affect the bioactive levels contained and its anti-inflammatory activity (in vivo).
Hubungan Motivasi, Kelelahan, dan Beban Kerja Terhadap Kinerja Perawat di Ruang Rawat Inap Rumah Sakit Ibu dan Anak (RSIA) Bunda Jakarta Tahun 2019 Pradnya Paramita; Dewi Sri Rahayuningsih
BIOEDUSCIENCE Vol 6 No 3 (2022): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/jbes/6310689

Abstract

Background: Based on performance appraisal data at RSIA Bunda Jakarta in 2016 shows that the percentage of nurses who have poor performance is 124 people (55.6%) and those who have good performance are 99 people (44.4%). And in 2017, it showed that the percentage of nurses who had poor performance was 64 people (36.2%), and those who had good performance were 113 people (63.8%). This study aimed to determine the relationship between motivation, fatigue, and workload on nurse performance in the Mother and Child Hospital Bunda Jakarta in February 2019. Method: Quantitative analytical research using a cross-sectional approach. The sample in this study was 72 nurses in the inpatient ward of Mother and Child Hospital Jakarta. Result: The bivariate results showed that there was a significant relationship between motivation (p 0.001), fatigue (p 0.038), and workload (p 0.001). Multivariate results showed that motivation and workload were the most dominant variables related to nursing performance (P<0.005). The workload variable is the most dominant variable with the most considerable Exp (β) of 5.625. Conclusion: Two variables were significantly (dominantly) related to nursing performance: motivation and workload.
Faktor-Faktor yang Berhubungan Antara Pemberi Pelayanan Kesehatan Gigi Terhadap Pasien Disaat Kejadian Coronavirus Disease 2019 (Covid-19) Pada Praktek Klinik Pradnya Paramita; Nuraini Nuraini
BIOEDUSCIENCE Vol 6 No 3 (2022): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/jbes/6310690

Abstract

Background: Coronavirus Disease 2019 (Covid-19) is currently a serious world problem with the number of cases always increasing every day. Methods: To find out the factors related to the incidence of coronavirus disease 2019 (Covid-19) in clinical practice, this research was conducted using a quantitative method equipped with a qualitative one and using a cross-sectional design. A sample of 198 people was selected using random sampling. The research instrument used a questionnaire. Out of 198 visitors at the clinic, Result: the respondents were female 53.0%, age > 18 years 70.2%, high school graduate education 86.4%, high minimum income 78.8%, knowledge good 50%, not densely occupied 86.4%, adequate ventilation 82.2% good room lighting 97.5%, washing hands 52.9%, maintaining cough etiquette 51.9%, wearing a mask 51.4%), not holding large-scale gatherings 80.8%, Not maintaining body immunity 69.2%, good facilities and infrastructure 80.8%, Access to remote services 53.0%, there is family support 59.6%. Conclusion: The chi-square test shows that there is a significant relationship between family support and the incidence of Covid-19, Washing Hands, Wearing a Mask, PSBB. Body Immunity, Cough Ethics, then the qualitative results show that almost all informants said they always prevent COVID-19 by implementing health protocols in the form of wearing masks and keeping a distance.
The Relation of TMPRSS2 Gene Polymorphism to COVID-19 Severity of Indonesian Population in Jakarta Erlin Listiyaningsih; Rizkyana Avissa; Shinta Dewi Permata Sari; Wening Tri Mawanti; Dewi Martalena
BIOEDUSCIENCE Vol 6 No 3 (2022): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/jbes/6310691

Abstract

Background: The COVID-19 disease caused by the SARS-CoV-2 virus has diverse symptoms, ranging from asymptomatic, mild symptoms such as flu-like illness and pneumonia to acute respiratory distress syndrome, which ends in death. Until now, the mechanism of the COVID-19 disease that causes widespread symptoms and the severity and factors that influence it are still unclear. During viral internalization, it needs to be cleaved by the serine protease encoded by the TMPRSS2 gene. It is hypothesized that higher expression of the TMPRSS2 gene causes higher virus internalization into cells, leading to more severe symptoms in patients. Methods: The Single Nucleotide Polymorphism Genotype Test was carried out to prove whether the TMPRSS2 gene affects the severity of COVID-19, as evidenced in other viral respiratory diseases. With a better understanding of gene expression related to this disease, it is hoped that we can better understand the mechanism of COVID-19 and establish better therapies and prevention against it. In this study, 68 COVID-19 patients participated and were categorized into two groups based on their clinical symptoms, namely mild symptoms without symptoms (n=12) and Moderate-Severe symptoms (n=56). PBMC cells were isolated from the patient. Then the DNA was extracted and used as a template in the SNP Genotyping of the TMPRSS2 rs2070788 gene variant. Results: The results showed that 35 samples had A/A homozygous genotypes, 29 A/G heterozygous samples, and 4 G/G homozygous samples. n=29) and heterozygous A/G (n=23), whereas only 4 were homozygous G/G. In addition, the homozygous G/G genotype was only detected in the moderate-severe group. Conclusions: A more significant number of samples from the asymptomatic mild symptom group is needed to statistically prove that homozygous G/G variants or G alleles are generally associated with the severity of COVID-19 patients.
Optimasi Konsentrasi Sukrosa dan Propilen Glikol dalam Formulasi Chewable Gummy Tablet Ekstrak Daun Kelor (Moringa oleifera L) Karina Citra Rani; Nikmatul Ikhrom Eka Jayani; Maulidia Setaratika; Syalza Mumpuni Kusuma Dewi
BIOEDUSCIENCE Vol 7 No 1 (2023): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/jbes/7110751

Abstract

Background: Moringa leaf extract is promising to develop into nutraceutical products, especially a chewable gummy. The desirable characteristics of chewable gummies are soft, elastic, springy and flexible. Gelatin is a widely used gelling agent which has been proven to maintain gel structure during storage. The other ingredients which also determine the chewable gel structure are fillers and plasticizers. The aim of this study was to determine the effect of sucrose and propylene glycol concentrations on Moringa leaf extract based on chewable gummy. Method: The preparation of chewable gummy tablets was carried out by the pour method. Factorial design study (22) was applied in this study to analyze the effect of two factors here in filler and plasticizer. Two levels of concentration were optimized in each factor, herein sucrose (30% and 35% concentration) and propylene glycol (2% and 4% concentration) on the physical characteristics of the gummy tablet. Result: The results of the factorial analysis showed that the increase in sucrose concentration will produce a longer dispersion time and lower swelling ratio. Meanwhile, the increase in propylene glycol decreases the syneresis potency. The alteration of physical characteristics was observed during 14 days of storage, particularly in dispersion time, swelling ratio, and syneresis percentage. Conclusion: Based on the results of a feasible design space, sucrose concentration (30-35%) and propylene glycol concentration (2-4%) were optimized in this study to produce the desirable characteristics of chewable gummy.
Uji Organoleptik Kombucha yang terbuat dari beberapa jenis teh dan waktu fermentasi berbeda Azrini Khaerah; Ardianto Ardianto
BIOEDUSCIENCE Vol 7 No 1 (2023): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/jbes/7110797

Abstract

Background: This research aims to find the best mixture of kombucha that can accept by the community in BTN Pa’jukukang, Bantaeng district. Kombucha is a fermented beverage made from tea and sugar mixed with the kombucha culture. A kombucha culture is a mixture of bacteria and yeast designated as SCOBY in this work. Methods: In this research, kombucha was made from 4 various teas, i.e., black tea, green tea, oolong tea, and white tea.  Each tea was fermented for 7 and 14 days. The kombucha tea samples were subjected to an organoleptic test based on the consumer's acceptance level. The organoleptic test data were analyzed using the hedonic and score test. Results: The test result showed that respondents preferred to choose the color, the smell, and the taste of the black kombucha tea which was fermented for 7 days. Conclusions: Furthermore, the observation of the physical characteristics of the tea showed that the longer the fermentation time, the more acidic the kombucha. This acidic kombucha resulted from the decreasing sugar level during the fermentation process due to the activity of bacteria and khamir in the SCOBY.
Analysis of Needs for the Development of Electronic Teaching Materials Based on Problem-Based Learning (PBL) Mahendra, Reno Esa; Sumah, Astrid Sri Wahyuni
BIOEDUSCIENCE Vol 7 No 2 (2023): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/jbes/10900

Abstract

Background: The learning process emphasizes students' active involvement and is oriented towards applying the concept of learning by doing and prioritizing personal experiences through observing, asking, and communicating to increase student creativity. However, reality proves that the application and implementation of learning in schools are not as expected. Some problems include the learning process only focusing on completing the subject matter, not on forming an understanding of the subject matter for students. This study aimed to analyze the need to develop electronic teaching materials according to the needs of students based on problem-based learning (PBL) learning models in biology subjects at MAN 1 Palembang school. Methods: The research used a qualitative descriptive method with a survey method by conducting interviews and questionnaires with biology teachers and students. Questionnaires, observations, and interviews provided data collection techniques. Results: The results obtained are textbooks and learning videos are the teaching materials most often used by teachers using discovery learning and project-based learning (PjBL) models. Students' activeness can be seen when the discussion activities and presentations of assignments take place, but it does not make students think critically. Conclusion: Teachers want problem-based learning (PBL) electronic teaching materials so that students can learn the material earlier and improve learning outcomes in material that is difficult for students to understand.
Pengaruh Model Pembelajaran Blended Learning dan Kreativitas Siswa Terhadap Hasil Belajar IPA Siswa Kelas VII Andri Irwansyah Irwansyah; Lukman Nulhakim; Suherman Suherman
BIOEDUSCIENCE Vol 7 No 1 (2023): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/jbes/7110920

Abstract

Background: This study aims to analyze differences in student learning outcomes between students whose learning uses a learning model (blended learning) and has high student creativity and students whose learning uses a learning model (discovery learning) and has high student creativity. Method: This study uses a quantitative method approach. This type of research uses a 2x2 factorial experiment method. The research population used was all students of class VII SMPN Labuan. Result: The results showed that: 1) There were differences in science learning outcomes between students whose learning activities used the blended learning model and students who used the discovery learning model. 2) There are differences in science learning outcomes between students who have high creativity and students who have low creativity. 3) There are differences in science learning outcomes between students who use blended learning models and have high creativity and students who use discovery learning models and high creativity. Conclusion: There are differences in science learning outcomes between students who use the blended learning model and have low creativity and students who use the discovery learning model and have low creativity.
Literasi Lingkungan Masyarakat Adat dan Masyarakat Perkotaan di Pulau Lombok Bidarinjani, Mouria; Rahardjanto, Abdulkadir; Setyawan, Dwi
BIOEDUSCIENCE Vol 7 No 2 (2023): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/jbes/11048

Abstract

Background: The high ability of community environmental literacy can form ideal environmental conditions, but indigenous peoples and urban communities have different understandings of environmental conditions. This study aimed to determine differences in the environmental literacy of indigenous peoples and urban communities on Lombok Island. Methods: The objects of this research are the indigenous people of Bayan Village, North Lombok, and the people of the Dasan Sari Environment, Mataram City, West Lombok: quantitative research methods, quantitative descriptive approaches, and survey research types. Data collection tools are observation, interviews, and questionnaires. Data analysis using SPSS, data analysis techniques by calculating the mean score of the questionnaire. Results: The study obtained a mean environmental literacy value for the indigenous people of Bayan Village at 214.37 and for the Dasan Sari Environmental community at 240.56. The results of the hypothesis testing in this study obtained a significance value greater than 0.05 and t-count < t-table. Conclusions: There was no real difference in environmental literacy between indigenous peoples and urban communities on Lombok Island.

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