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INDONESIA
BIOEDUSCIENCE
ISSN : 2614154X     EISSN : 26141558     DOI : -
BIOEDUSCIENCE is an open access journal that publishes research in the field of Biology and Biosain Education such as: Applied and implemented in education and learning, Botany, Zoology, Microbiology, Ecology, Biotechnology, Molecular Biology, Genetics, Bioinformatics, Cell and Developmental Biology, Biodiversity and Bioconservation. BIOEDUSCIENCE is published by Biology Education Study Program, Universitas Muhammadiyah Prof. Dr. Hamka, Indonesia regularly in June and December. ISSN : 2614-1558; P-ISSN : 2614-154X.
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Articles 544 Documents
Analysis of Molecular Interactions of 8-Gingerol Compounds in Ginger (Zingiber officinale) as ACE Inhibitor Yohanes Bare; Mansur s; Aprianus Pani Pili; Maria Helvina
BIOEDUSCIENCE Vol 4 No 2 (2020): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1017.778 KB) | DOI: 10.22236/j.bes/424944

Abstract

Background: Hypertension is a disease with increasing characteristics of blood pressure. The ACE gene has a role in the conversion of ATI to ATII in hypertensive conditions. Healing is done by using the 8-gingerol content contained in ginger. The purpose of this study is to analyze the molecular interaction that occurs between 8-gingerol and ACE. Method: ACE model proteins (ID: 3bkk) were obtained from the Bank Data Protein database (PDB) through 8-gingerol ligands (CID: 168114) obtained from the PubChem database. ACE and 8-gingerol were docked by Discovery Study Client 4.1 software. Analysis of amino acid residues, binding energy, Van der Waals forces, and hydrogen bonds formed using Discovery Studio Client 4.1. Results: The interaction between 8-gingerol and ACE showed that there were seven amino acid residues that interacted with 8-gingerol, also found hydrogen bonds, hydrophobic and Van der Waals forces that strengthen and stabilize these bonds. Conclusion: the interaction of 8-ginger with the active side of ACE is determined as an ACE inhibitor, the inhibition is a significant effect on the obstruction of ACE conversion.
Hubungan Kekerabatan Fenetik Famili Apocynaceae Berdasarkan Karakter Morfologi dan Anatomi Ahsanul Buduri Agustiar; Dewi Masyitoh; Irda Dwi Fibriana; Adesilvi Saisatul Khumairoh; Kurnia Alfi Rianti; Norma Fitriani; Muhammad Harissuddin; Hafidha Asni Akmalia
BIOEDUSCIENCE Vol 4 No 2 (2020): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (921.616 KB) | DOI: 10.22236/j.bes/424945

Abstract

Background: Biodiversity in Indonesia is so diverse, including in Apocynaceae plants that is why it is important to study the kinship relationship to find out the kinship of Apocynaceae. The purpose of this study was to determine phenetic kinship through morphological and anatomical evidence from four members of the Apocynaceae family. Methods: The method used in this research is descriptive qualitative and quantitative method. The samples in this study were four species of Apocynaceae family members, including Adenium obesum, Plumeria rubra, Catharanthus roseus, and Allamanda cathartica. The indicators used were the morphological traits of stems, leaves, and flowers and the anatomical trait of stomata. Results: The result showed that the phenetic kinship of the four species of the Apocynaceae family member namely Alamanda cathartica had a distant kinship relationship with the other species with a similarity value of 31%. Conclusions: Thus, the familial relationship between species in the Apocynaceae family in terms of morphological and anatomical characters that have a close relationship with Plumeria rubra and Adenium obesum with a similarity value of 44% and the most distant Alamanda cathartica with a similarity value of 31%.
Motivasi Mahasiswa Terhadap Penggunaan Penuntun Praktikum Fisiologi Hewan Berbasis Inkuiri Terbimbing Diana Susanti; Rina Widiana; Ramadhan Sumarmin; Silvi Susanti
BIOEDUSCIENCE Vol 5 No 1 (2021): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (258.308 KB) | DOI: 10.22236/j.bes/514994

Abstract

Guidance on guided animal inquiry based practicology has been developed with valid, practical and effective results. The guide developed is guided inquiry-oriented which can help students find their own knowledge when practicum activities are carried out. Guides developed are also in accordance with the correct guiding component. The purpose of this study is to see the results of student motivation in using guided inquiry-based physiology practicum guides. This research is a development study using the 4D model, the data is processed using a percentage formula. The results of data processing show that the motivation of students who use practicum guides get a percentage of 80.2% (highly motivated) and those who do not use practicum guides is 84.14% (highly motivated) It can be concluded that students are highly motivated towards the use of practicum guided animal physiology guides
Keanekaragaman serangga parasitoid (Ordo: Hymenoptera) pada areal persawahan dan kebun sayur Manap Trianto; Varsha Salsabillah
BIOEDUSCIENCE Vol 5 No 1 (2021): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (373.985 KB) | DOI: 10.22236/j.bes/515049

Abstract

Background: The Hymenoptera Order is one of the most dominant orders in the insect class, both in number of species and in their distribution in various habitats. The role of the Hymenoptera Order, especially parasitoids, is very important in a habitat. The purpose of this study was to determine the diversity of parasitoid insects, especially the order Hymenoptera in rice fields and vegetable gardens. Methods: This research is analytic descriptive. The research method used is a line transect using a sampling technique. The study was conducted in two research areas (rice fields and vegetable gardens) and used three fishing gears (malaise traps, buckets, and insect nets). Results: The results showed that the total number of insects caught was 5037 individuals from 10 orders and 80 family. The diversity of parasitoid insects in this study is in the rice fields H' = 1.80 (moderate diversity) and vegetable gardens H' = 2.26 (moderate diversity). Conclusions: Hymenoptera parasitoid insect diversity was highest in the vegetable garden area.
Potensi Antibakteria Tanaman Bidara Laut (Ximenia americana) Terhadap Bakteri Vibrio alginolyticus dan V. parahaemolyticus Ramses; Fenny Agustina; R. Pramuanggit Panggih Nugroho
BIOEDUSCIENCE Vol 5 No 1 (2021): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (451.422 KB) | DOI: 10.22236/j.bes/515091

Abstract

Background: Vibriosis is currently still a major problem in marine aquaculture and is highly dependent on availability of antibacterial agents in its handling. Investigation of antibacterial potential of the coastal plants of Bidara Laut (Ximenia americana) has been carried out. Methods: Parts of the X. americana plant taken are Old Fruit, Young Fruit, Old Leaf, and Young Leaf. A total of ± 200 grams of each part of X. americana plant was taken to be extracted using maceration method. The antibacterial activity test was performed using the Kirby-Bauer disc diffusion method on Muller Hinton Agar (MHA) media. Observations were made in time units, namely every 6 hours of incubation for 24 hours. Results: The tested extract of plant parts of X. americana showed an inhibition zone against the growth of V. alginolyticus and V. parahaemolyticus bacteria in each replication in all-time units of observation. Of the four types of extracts tested, old leaves showed strong category resistance to V. alginolyticus with the highest clear zone diameter of 16 mm (average 14.67 mm) at 6 hours incubation. Young leaves gave the highest of 18 mm (average 16.33 mm) against V. parahaemolyticus at 6 hours incubation. Conclusions: X. americana plants have potential for antibacterial against Vibriosis disease in aquaculture. The ability of power to be seen tended to decrease for all tests until the end of observation, but until the end of observation, the ability of extract inhibition of all parts of the plant was still in the moderate to strong category.
Media Motion Graphics Berbasis E-Learning Untuk Meningkatkan Motivasi Belajar Siswa Materi Keanekaragaman Hayati Ervan Johan Wicaksana; Binanggra Alpa Pebriand; Pramana Atmadja; Wikanso
BIOEDUSCIENCE Vol 5 No 1 (2021): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (318.359 KB) | DOI: 10.22236/j.bes/515118

Abstract

Background: Biology is a pure science that is analytical and systematic. It relates to the reality of the problems experienced by students in the current biology learning process, which is a monotonous way of learning and tends to make students feel bored with the learning process carried out, so that the teaching material delivered by the teacher or educator is difficult to understand by students. This class action research aims to improve student learning motivation on Biodiversity material. Methods: This class action research was conducted in two cycles; the first cycle was carried out with one meeting and the second cycle was carried out with one meeting. Each cycle is the application of Kemmis and Mc Taggart's classroom action research consisting of 4 stages: planning, action, observation, and reflection. Results: The results of this study are an increase in learning motivation of students in each cycle. Conclusions: Based on these results, it can be concluded that the Motion Graphics learning media based on e-learning has succeeded in increasing students' learning motivation on Biodiversity material.
Subchronic Toxicity Test of Indian Almond (Terminalia catappa) Leaves Water Extract on The Liver Histology of Mice (Mus musculus) Nugroho Rudy; Ni Cening Sri Puspa; Retno Aryani; Widha Prahastika; Rudianto; Hetty Manurung
BIOEDUSCIENCE Vol 4 No 2 (2020): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (810.974 KB) | DOI: 10.22236/j.bes/425173

Abstract

Background: Indian almond (Terminalia catappa) is used as an alternative medicine by the community to treat various diseases. However, limited research has been conducted on the subchronic toxicity of Indian almond water extracts on the liver. Present study aimed to determine the subchronic toxic effects of Indian almond leaf water extract on the liver histology of mice and to evaluate the safe dose of Indian almond leaf water extract with various doses (125, 250, 500, 750 and 1000 mg/kg). Methods: In total of 33 male mice were randomly divided into 11 groups, each group consisting of three mice as replication. For 30 days, mice in five treatment groups were orally treated every day with water extracts of green Indian almond leaf while other five groups were given water extracts of brown Indian almond leaves and compare with control group. At the end of day 30, all mice were sacrificed, and hepar was taken out for histological preparations. The histopathological changes in the liver was observed and assessed based on histological damage in the term of degeneration and necrosis. Results: The administration of green and brown Indian almond water extract at doses of 125, 250, 500, 750 and 1000 mg / kg BB showed a toxic effect on the liver of mice. The toxic effect was due to the high doses, causing a cell swelling damage and increased liver necrosis. Conclusion: Indian almond leaf water extract can cause toxic effects on the liver of mice at the doses implemented.
HA Aktivitas Antimikroba dan Identifikasi Gen Penyandi Enterocins isolat Enterococcus faecalis K2B1 dari Susu Kerbau Belang Toraja: Antimikroba dan Gen Penyandi Hasria Alang; Joni Kusnadi; Tri Ardyati; Suharjono
BIOEDUSCIENCE Vol 4 No 2 (2020): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (656.134 KB) | DOI: 10.22236/j.bes/425193

Abstract

Background: Enterocin in Enterococcus is coded by enterocin encoding genes namely A, B, P and L50A / B. The purpose of this study was to identify enterocin gene encoding enterococcus faecalis K2B1 probiotic candidate from Belang Toraja buffalo milk and antimicrobial activity to S. typhi. Methods: identification of enterocin gene encoding using ent A, B, P and L50A / B, partial purification using ammonium sulfate on 80 % concentration and antimicrobial activity against to Salmonella typhi using disk diffusion method. The results of PCR amplification are then sequenced and BLASTX on NCBI. Result: Antimicrobial activity of Precipitate and crude against S. typhi are 193 and 201 respectively. Identification gene encoding enterocin shows that Ent A, B and P cannot be amplified and only EntL50A / B can be amplified with a sequence size of 86 bp. The sequence of enterocin encoding genes in E. faecalis K2B1 has 94% similarity with hypothetical protein EB34_00789 E. faecalis on GenBank with accession number RBR60004.1 Conclusion: EntL50A / B E. faecalis K2B1 has a size of 86 bp and is 94% identical to the hypothetical protein EB34_00789 and Enterocin can be used as antimicrobial or bio preservative.
Analisis Kemampuan Literasi Bahasa dalam Konteks Pembelajaran Biologi Jihan Azhaar Ramadhanty; Vita Meylani; Edi Hernawan
BIOEDUSCIENCE Vol 4 No 2 (2020): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (514.441 KB) | DOI: 10.22236/j.bes/425194

Abstract

Background: The results of PISA showed that Indonesian students' literacy skills in the field of science are still low. Until now, the cause of the problem is still little information reported. This study was conducted to analyze the language literacy skills of students in biological learning contexts. Methods: the methods used in the research is mixed methods research. This research involved 72 science program students who were selected by purposive sampling. The data were gained by observations, interviews and giving the posttest consisting of 17 questions of multiple-choice based on the Programme for International Student Assessment (PISA) indicator for language literacy in biological learning. Results: That the analysis of language literacy in the context of Biological learning has an excellent literacy with a high category. The research showed that the highest average grade of language literacy was in the integrate and interpret aspects of 75,00. Meanwhile, the lowest average grade in the reflect and evaluate aspects was 57,00. The average overall grade in the language literacy on Biological learning was 70,22. Conclusion: Sustainable literacy activities stimulate higher-order thinking skills, especially in the field of science, because language literacy skills can indirectly affect students' outcomes on scientific skills.
Pembelajaran Daring berbasis Google Classroom terhadap Hasil Belajar Konsep Reproduksi pada Kelas Sains Rosalia Dwi Putri; Purwati Kuswarini Suprapto; Egi Nuryadin
BIOEDUSCIENCE Vol 5 No 1 (2021): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (354.514 KB) | DOI: 10.22236/j.bes/515241

Abstract

Background: This research shows the improvement of student learning outcomes with Google Classroom-based learning on the concept of human reproductive systems in science classes. Methods: The research method used is the pre-experimental method one-group pretest-posttest design. Samples were taken in non-probability sampling with purposive sampling, which is a science class of 38 students. The treatment given in this study is learning done online using google classroom application, all activities in google classroom on the concept of the human reproductive system. Results: The results of the analysis showed with t calculate (-15.39) greater than t table (-2.04). Based on data analysis and testing, it can be interpreted that there is an increase in student learning outcomes with google classroom-based online learning. The increase is seen from the N-gain value (0.57), which interprets learning outcomes in medium theories. Conclusions: Effectivity learning activities need to be presented by teachers in the face of pandemic situations, although they cannot be done for luring. Google Classroom based online learning can package distance learning more effectively, which has an impact on improving student learning outcomes.

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