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INDONESIA
Indonesian Journal of Cardiology
Published by Indonesian Heart Association
ISSN : 28303105     EISSN : 29647304     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology
Indonesian Journal of Cardiology (IJC) is a peer-reviewed and open-access journal established by Indonesian Heart Association (IHA)/Perhimpunan Dokter Spesialis Kardiovaskular Indonesia (PERKI) [www.inaheart.org] on the year 1979. This journal is published to meet the needs of physicians and other health professionals for scientific articles in the cardiovascular field. All articles (research, case report, review article, and others) should be original and has never been published in any magazine/journal. Prior to publication, every manuscript will be subjected to double-blind review by peer-reviewers. We consider articles on all aspects of the cardiovascular system including clinical, translational, epidemiological, and basic studies. Subjects suitable for publication include but are not limited to the following fields: Acute Cardiovascular Care Arrhythmia / Cardiac Electrophysiology Cardiovascular Imaging Cardiovascular Pharmacotherapy Cardiovascular Public Health Policy Cardiovascular Rehabilitation Cardiovascular Research General Cardiology Heart Failure Hypertension Interventional Cardiology Pediatric Cardiology Preventive Cardiology Vascular Medicine
Arjuna Subject : Kedokteran - Cardiology and Cardiovascular Medicine
Articles 712 Documents
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Implikasi Klinis Gambaran Elektrokardiogram Low-voltage Andrianto Andrianto; Putri Rachmawati Dewi
Jurnal Kardiologi Indonesia Vol. 37, No. 4 Oktober - Desember 2016
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v37i4.585

Abstract

Low-voltage on the surface electrocardiogram (ECG) is classically defined as peak-to-peak QRS voltage less than 5 mm in all limb leads and less than 10 mm in all precordial leads. There are many causes of low QRS voltage (LQRSV), and they can be differentiated into those due to the deficient heart’s generated potentials (cardiac causes) and those due to the attenuating influences of the pericardial space and pericardium, or the passive body volume conductor, enveloping the heart (extracardiac causes). In some patients, LQRSV voltage may only represent a normal variant. The ECG challenge for this issue is to examine the physiological, anatomical and electrical equipment problems of low-voltage, or low-amplitude, ECG and to suggest methods for troubleshooting the low-voltage ECG to ensure reliable cardiac monitoring.
Peran Asam Lemak Omega-3 pada Dislipidemia dan Penyakit Kardiovaskular Grace Fonda; Raymond Pranata; Hadrian Deka
Jurnal Kardiologi Indonesia Vol. 37, No. 4 Oktober - Desember 2016
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v37i4.586

Abstract

Globally, coronary heart disease (CHD) is a leading cause of mortality and morbidity, especially in developing countries. Both marine and plants sources of omega-3 fatty acids has been shown to be beneficial in reducing CHD mortality. Beside of anti-arrhythmic effects, omega-3 has been shown anti-thrombotic and anti-atherosclerotic effect. In 2011, US population spent about 25 billion US dollar for omega-3 supplement; it is projected to be 35 billion US dollar in the year 2016. Several reviews on randomized controlled trial conclude that omega-3 fatty acids reduced plasma triglyceride level consistently in a dose-dependent fashion. Other beneficial effects on blood pressure, endothelial function and high density lipoprotein (HDL) level participate in lowering CHD mortality. American Heart Association (AHA) recommended routine fish consumption as secondary prevention in patient at risk. Omega-3 fatty acids role in primary prevention is inconclusive and need further investigation regarding cost-benefit and bleeding risk.
Pelayanan Kesehatan Kardiologi di Era Badan Penyelenggara Jaminan Sosial Kesehatan: Sebuah Antitesis Januar Wibawa Martha
Jurnal Kardiologi Indonesia Vol. 38, No. 1 Januari-Maret 2017
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v38i1.670

Abstract

Sehat adalah kebutuhan dasar setiap manusia, dan menjamin kesehatan warga adalah tugas setiap negara. Di sisi lain, untuk menjaga kesehatan diperlukan biaya yang tidak sedikit.Pada awal praktik pengobatan, pembiayaan kesehatan ditanggung oleh perseorangan. Pasien berobat ke dokter dan sebagai tanda terima kasih, pasien memberikan penghargaan berupa uang atau bentuk lainnya. Perkembangan sistem pembiayaan kesehatan dewasa ini mengarah kepada pembiayaan kolektif ketika masyarakat yang menjadi peserta dibebani premi yang dikumpulkan oleh suatu badan tertentu dan dipakai apabila peserta tersebut menerima pelayanan kesehatan. Pada dasarnya, sistem pembiayaan kolektif ini sangat baik karena akses terhadap pelayanan kesehatan menjadi lebih terbuka, biaya pelayanan kesehatan seharusnya menjadi lebih murah, dan dapat terjadi pembiayaan silang untuk mereka yang kurang mampu. Sistem pembiayaan kesehatan secara kolektif ini dikenal dengan asuransi kesehatan, dan yang tengah menjadi primadona di negara kita adalah asuransi kesehatan yang diselenggarakan oleh Badan Penyelenggara Jaminan Sosial – Kesehatan (BPJS-K). Meskipun banyak manfaat yang dapat diperoleh dari BPJS-K, apakah ada kelemahan dari sistem ini ditinjau dari profesional medis? Beberapa prinsip pengelolaan pasien yang memiliki potensi bermasalah pada pelayanan kesehatan berbasis asuransi kesehatan adalah sebagai berikut.
Efek Pemberian Statin terhadap Proliferasi Endothelial Progenitor Cell pada Darah Tepi Penderita Penyakit Jantung Koroner Stabil Feranti Meuthia; Yudi Her Oktaviono; Djoko Soemantri
Jurnal Kardiologi Indonesia Vol. 38, No. 1 Januari-Maret 2017
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v38i1.672

Abstract

Background: Atherosclerotic lesions develop as the result of an inflammatory process initiated by endothelial damage. Endothelial progrenitor cells (EPCs), which is derived from bone marrow, participate in endothelial repair and new vessel growth. Cardiovascular pharmacotherapies have been shown to improve overall numbers and function of EPCs in patients with cardiovascular risk and cardiovascular disease. Studies have reported that statins exert beneficial effects on EPCs by enhancing EPC proliferation and differentiation. Thus, we require a research to analyze the effects of three different statins on EPC proliferation. The objective of this study is to analyze the effect of statins on EPC proliferation from peripheral blood of stable coronary artery disease patient.Methods: This is an in vitro true experimental post-test only control group design. The mononuclear cells (MNCs) were isolated from peripheral blood of stable coronary artery disease patient and were cultured in CFU-Hill medium for three days. Then samples were put into four groups, simvastatin experiment group, atorvastatin experiment group, rosuvastatin experiment group and control group. Each experiment group was divided into three subgroups with different doses, 0.1 ?mol/L, 0.5 ?mol/L, and 2.5 ?mol/L then incubated for 48 hours. EPC proliferation was evaluated afterwards with MTT cell proliferation assay. Immunocytochemistry method was performed for EPC identification to evaluate expression of CD34+. CFU-Hills were observed to confirm functional characteristics of EPC. Data were analyzed by independent T-test and ANOVA.Results: MTT cell proliferation assay showed a significant increase of EPC proliferation in simvastatin, atorvastatin, and rosuvastatin groups compared with control group (0.237±0.007, 0.248±0.01, 0.231±0.008 vs 0.17±0.008, p<0.05). It also revealed significant difference in EPC proliferation between each experiment groups, which atorvastatin showed the highest effect. EPC proliferation in atorvastatin is higher than simvastatin group (0.248±0.01 vs. 0.237±0.007, p<0.05), and simvastatin is also higher than rosuvastatin group (0.237±0.007 vs. 0.231±0.008, p<0.05). CFU-Hill counts demonstrated highest number in rosuvastatin group, followed by atorvastatin, and simvastatin. Immunocytochemistry showed positive expression of CD34.Conclusion: Statins increase EPC proliferation from peripheral blood of stable coronary artery disease patient. Atorvastatin showed the highest EPC proliferation, followed by simvastatin, and rosuvastatin. Each statins increased EPC proliferation dose-dependently.
Hubungan antara Rasio Panjang Katup Mitral Posterior-Anterior dan Derajat Keparahan Stenosis Mitral Rematik Citra Kiki Krevani; Mefri Yanni; Yerizal Karani; Masrul Syafri
Jurnal Kardiologi Indonesia Vol. 38, No. 1 Januari-Maret 2017
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v38i1.673

Abstract

Background: Rheumatic mitral stenosis (RMS) is the cause of mitral valve disease commonly found in developing countries. Determining severity of RMS is very important, related with prognosis and management of the disease. Current echocardiography methods have advantages and disadvantages in determining the severity of RMS. Posterior to anterior mitral valve leaflets length ratio (PMVL/ AMVL ratio) was proposed to be one of the semi-quantitative measurement which offered a simple, easy and accurate method in determining the severity of RMS. The aim of this study was to see the association of posterior to anterior mitral valve leaflets length ratio with severity of rheumatic mitral stenosis.Methods: This was a cross-sectional descriptive analytic study. The subjects were all patients with rheumatic mitral stenosis who underwent echocardiography examination to measure the PMVL/AMVL ratio as well as determining the severity based on mitral valve area (MVA) planimetry. One-way ANOVA analytic test was used to assess the association of ratio PMVL/AMVL and severity of the RMS.Results: Of 71 patients included in this study, there were 19 mild RMS, 19 moderate RMS and 33 severe RMS patients. Majority of the subjects were female with age range from 38 to 43 years and have atrial fibrillation. From echocardiography examination, the mean EF +/- 55% with increased LAVI and SPAP according to the severity of the RMS (LAVI; 44±1.3 vs. 55±1.5 vs. 74±1.7 ml/m2 SPAP; 29±1.2 vs. 46±9.0 vs. 68±1.4 mmHg). There was a significant difference in the length of PMVL in mild, moderate and severe RMS (28±5.6 vs. 22±4.0 vs. 17±5.2 mm; p<0.001), but no significant difference in the length of AMVL (33±5.5 vs 33±5.4 vs 32±5.1mm; p=0.93) respectively. The PMVL/AMVL ratio had statistically significant association with severity of RMS (p<0.001).Conclusion: The PMVL/AMVL ratio is significantly associated with severity of RMS.
Rasio Panjang Daun Posterior dengan Daun Anterior Katup Mitral pada Gambaran Ekokardiografi sebagai Parameter Sederhana untuk Menentukan Derajat Keparahan Stenosis Mitral Zunaidi Syahputra; Nizam Zikri Akbar; Andre Pasha Ketaren; Harris Hasan
Jurnal Kardiologi Indonesia Vol. 38, No. 1 Januari-Maret 2017
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v38i1.674

Abstract

Background: Determining the severity of mitral stenosis is important for both prognostic and therapeutic reasons. TTE is the gold standard method for assessment of severity mitral stenosis by using planimetry and pressure half time (PHT). Planimetry is accurate but highly operator dependent. PHT is affected by changes in preload or left ventricular compliance. In this study, we evaluate the posterior to anterior mitral valve leaflets length ratio as a novel simple parameter that can be used in peripheral by using common ultrasound to assess the severity of MS.Methods: This cross-sectional study involved 75 patients with rheumatic mitral stenosis (MS) who evaluate echocardiography in Adam Malik Hospital . The severity of MS was classified by planimetry and PHT. The posterior to anterior mitral valve leaflets length ratio was obtained by dividing posterior mitral valve leaflet length to anterior mitral valve leaflets length in the parasternal long axis views at the end diastole.Results: Severe (61.3%), moderate (32%), mild (6.7 %) MS. There was a strong correlation with the posterior to anterior mitral valve leaflets length ratio and mitral valve area by planimetry in spearman correlation ( r=0.892, p<0.001). ROC analysis of the posterior to anterior mitral valve leaflets length ratio with cut-off point < 0.68 could predict severe MS with sensitivity of 97%, specificity of 93%, positive predictive value of 96%, LR (+) of 13.85. Intra-observer and intra-observer variability of this parameter was good (Kappa value of 0.760–0.765) and significant (p< 0.001). Goodness of fit test with Hosmer-Lemeshow test showed this parameter fit with the data.Conclusion: The posterior to anterior mitral valve leaflets length ratio<0.68 can be used as a simple parameter in determining the severity of mitral stenosis with high sensitivity and specificity.
Laporan Dua Kasus Sindrom Twiddler pada Pasien dengan Pemasangan Implanted Cardioverter-Defibrillator dan Permanent Pacemaker Pipiet Wulandari; Sunu B Raharjo; Dicky A Hanafy; Lina Haryati; Yoga Yuniadi
Jurnal Kardiologi Indonesia Vol. 38, No. 1 Januari-Maret 2017
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v38i1.675

Abstract

Background: Twiddler syndrome is an infrequent but potentially dangerous complication of device therapy for dysrhythmias. This syndrome results from manipulation of implanted pulse generator by the patient, leading to traction and subsequent lead dislodgement. It can also occur spontaneously. It has been increasingly reported with pacemaker or implantable cardioverter-defibrillators (ICDs). In this reports, we describe two patients with Twiddler syndrome with substantial retraction of their lead who denied any manipulation of their device.Case Illustration: The first patient was a 56 year-old man with single-chamber ICD due to dilated cardiomyopathy (DCM) with congestive heart failure and severe systolic left ventricular dysfunction (ejection fraction 18%). The dislodged lead causing rhythmical twitching of left pectoral muscles and abdominal pulsations. The second patient was a 69 year-old man with dual-chamber pacemaker due to total atrioventricular block with normal systolic left ventricular function (ejection fraction 70%). It manifested as dyspnea on effort, and he also underwent pacemaker implantation. They underwent primary devices implantation at April 2016 and reposition of generators and its leads in December 2016. The first and second patients denied of manipulating the generator of ICD or pacemaker and rotated their left arm and right arm, respectively, after implantation.Summary: Other unconscious arm abduction during sleep or increased muscular activity of the shoulder and arm might have led to repetitive motions within the pocket and dislodge the device. Adequate individualized patient and family education and regular evaluation every 6 month of the leads position with fluoroscopy or chest X-ray is advisable.
Dilema Penggunaan Statin dan Aspirin sebagai Alternatif Pencegahan Primer Penyakit Kardiovaskular Henry Sutanto
Jurnal Kardiologi Indonesia Vol. 38, No. 1 Januari-Maret 2017
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v38i1.676

Abstract

Cardiovascular disease is one of the deadliest diseases in the world. Nowadays, alongside the developments of various medical therapeutic strategies, there is a decreasing trend of cardiovascular mortality. However, this reduction is not adequate and needs to be supported by cardiovascular prevention approaches. Statins and aspirin are two of cardiovascular drugs that are believed to be beneficial in cardiovascular prevention. Their magnificent efficacies in the secondary prevention setting lead them to be used in the primary prevention. However, some safety issues associated with the drugs should be considered. For that reason, based on previous trials and studies, some recommendations regarding the efficacy-safety issues are developed.
Cardiac Magnetic Resonance: A Multi-Parametric Imaging to Guide Management in Chronic Ischemic Heart Failure Novi Anggriyani
Jurnal Kardiologi Indonesia Vol. 38, No. 1 Januari-Maret 2017
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v38i1.678

Abstract

Chronic heart failure is a major public-health problem with a high prevalence, high mortality and complex treatment. A comprehensive analysis is needed to provide optimal therapy to these patients. Non-invasive imaging plays a central part by offering a complete approach in patients with ischemic heart disease (IHD). Cardiac magnetic resonance imaging (CMR) has emerged as an established advanced multi-parametric imaging modality for the functional and anatomical assessment of cardiovascular disease. This review describes the practical aspects of CMR imaging, and then discusses the role of CMR in the diagnosis and management of chronic IHD, its infarct related complications, such as secondary mitral regurgitation, left ventricular (LV) thrombus, and ventricular tachycardia (VT).
Sadapan Lewis: Mengungkap Gelombang P yang Tersembunyi Harmoko, Afandi Dwi; Sulastomo, Heru
Jurnal Kardiologi Indonesia Vol 42 No 4 (2021): Indonesian Journal of Cardiology: October - December 2021
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.1165

Abstract

Background. The Lewis lead configuration can help to detect atrial activity and its relationship to ventricular activity, so diagnosis can be achieved more accurately. With Lewis lead ECG, it will make easier to make a diagnosis, especially in identifying electrical activity in the atrium. Case Illustration. Case 1. A 61-year-old male with decreased consciousness et causa metabolic. From a standard 12-lead ECG, the P waves are difficult to identify, and at first glance it looks like atrial fibrillation. From the Lewis ECG in lead I, it appears that the QRS wave is always preceded by a P wave, with different morphologies (more than 3 forms), that showed as multifocal atrial tachycardia (MAT) with a heart rate of 120 beats / minute. Case 2. The 58-year-old male patient complained of typical ischemic chest pain and palpitations. A standard 12 lead ECG examination revealed a rhythmic tachycardia with a wide QRS wave at a rate of 210 beats / minute. From the Lewis ECG in lead I, we can see that the P waves that appear are not always followed by QRS. Thus, it can be seen that the AV dissociation is a VT so that VT management can be done immediately. Case 3. A 65-year-old male patient diagnosed with grade 5 CKD on dialysis. From a standard 12 lead ECG examination, a wide QRS wave with a P wave is obtained which is sometimes seen behind the QRS wave, making the diagnosis difficult to establish. From the Lewis ECG in lead I, it appears that the P wave always appears at the end of the QRS wave, so it can be seen that the rhythm from the ECG is derived from accelerated idioventricular rhythm with ventriculoatrial conduction. Conclusion. The accuracy of ECG interpretation is needed to determine the next treatment for the patient. Through the ECG examination with the Lewis lead method, the cardiac electrical activity will be more visible, so it will be very helpful in the interpretation of the ECG in cases that are not clear on the standard 12 lead ECG examination.

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