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INDONESIA
Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia)
Published by Perkumpulan Obstetri dan Ginekologi Indonesia
ISSN : 23386401     EISSN : 23387335     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
The Indonesian Journal of Obstetrics and Gynecology is an official publication of the Indonesian Society of Obstetrics and Gynekology. INAJOG is published quarterly.
Arjuna Subject : -
Articles 1,760 Documents
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Epidemiology Data of Ovarian Cancer in Dr. Cipto Mangunkusumo Hospital, Jakarta Noela, Fransisca; Nuryanto, Kartiwa H
Indonesian Journal of Obstetrics and Gynecology Volume. 4, No. 2, April 2016
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (104.844 KB) | DOI: 10.32771/inajog.v4i2.84

Abstract

Objective: To describe the incidence of ovarian cancer and its characteristic in Dr. Cipto Mangunkusumo Hospital in the last 5 years. Method: This was cross sectional study design. The data was collected from Gynecology Oncology Division Cancer Registry and Dr. Cipto Mangunkusumo Hospital medical record from January 2009 to December 2013; follow up was performed to know the 4-years survival rate. Result: There were 98 subjects in this study. The majority incidence of ovarian cancer was 45-54 years old (33.6%); the incidence of ovarian cancer decreased with the increased number of parity; the majority histotype was epithelial (76.5%); and most of them were diagnosed on advanced stage (55.1%). The 4-year survival rate for epithelial type was 77%; germinal type was 83.3%; and stromal type was 100%. Based on therapy, the 4-year survival rate was 84.1% for surgical only; 83.3% in adjuvant chemotherapy group; and 68.4% in neoadjuvant chemotherapy. In the group of adjuvant chemotherapy, there was 63% patients with complete response and 41.2% patients with complete response in neoadjuvant chemotherapy. Conclusion: The highest incidence of ovarian cancer in Dr. Cipto Mangunkusumo Hospital belongs to the age of reproductive women (≤ 55 years old) with the highest incidence occurs in nulliparity women. Most of the ovarian cancer cases are diagnosed in advanced stage (stage III-IV). [Indones J Obstet Gynecol 2016; 4-2: 101-106] Keywords: age, histotype, ovarian cancer, parity, response, stage, survival, treatment
Malondialdehyde Levels in Preeclampsia before and after Delivery Rumopa, Harold; Wagey, Freddy W.; Suparman, Eddy
Indonesian Journal of Obstetrics and Gynecology Volume 6 No. 3 July 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (101.193 KB) | DOI: 10.32771/inajog.v6i3.777

Abstract

  Objective: Determine differences plasma levels MDA in preeclampsiabefore and 2 hours after delivery.   Methods: This was an analytic cross-sectional study. Subjectconsists of 23 pregnancies with preeclampsia, where 23 bloodsamples taken before delivery and 23 were taken 2 hours afterdelivery. This study was conducted from August 2016 untilDecember 2016 at Department of Obstetrics and GynecologyFaculty of Medicine Universitas Sam Ratulangi / Prof. Dr. R. D.Kandou Hospital Manado and satellite hospital. Samples weretaken from plasma and analysed using HPLC method at Prodiaclinical laboratory.   Results: In patients with severe preeclampsia before deliverywe found average value (1.4796  0.40819 nmol/ml), minimumvalue (1.03 nmol/ml) and maximal value (2.77 nmol/ml)and 2 hours after delivery with average value (1.2470 0.34324 nmol/ml), minimum value (0.91 nmol/ml), and maximumvalue (2.47 nmol/ml). by using Wilcoxon test, we foundthere were significant differences in plasma levels of MDA (p =0.000).   Conclusion: This significant difference suggests that decreasedplasma levels of MDA 2 hours after delivery and gives the sense thatthere is a relationship between oxidative stress of cells with severepreeclampsia before and shortly after delivery, that MDA is an indicatorof oxidative stress.   Keywords: malondialdehyde, oxidative stress, peroxidation lipid,preeclampsia
Placental Growth Factor Level is Lower in Early-Onset Preeclampsia, while Tumor Necrosis Factor Alpha Level does not Show any Difference between Early and Late Onset Preeclampsia Ekapatria, Christofani
Indonesian Journal of Obstetrics and Gynecology Volume. 36, No. 4, October 2012
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (94.737 KB)

Abstract

Objective: To analyze the difference of PlGF and TNF-α serum level between early-onset and late-onset preeclampsia. Method: This is a cross-sectional analytic comparative study comparing serum level of PlGF and TNF-α between groups with earlyand late-onset preeclampsia. Each group consists of 32 subjects who met inclusion criteria and presented to Dr. Hasan Sadikin Hospital or its district hospitals in September - November 2012. Statistical analysis was performed with Kolmogorov Smirnov test, Saphiro-Wilk test, and non-parametric Mann-Whitney test. Result: Mean of PlGF serum level in the group with early-onset preeclampsia is 53.0344±38.07140 pg/ml, while mean of which in the group with late-onset preeclampsia is 241.8063±192.8373 pg/ml (p
Monoplant® the Indonesian Implant: The Overview of Implant and Its Development Gunardi, Eka R.
Indonesian Journal of Obstetrics and Gynecology Volume. 35, No. 1, January 2011
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (69.55 KB)

Abstract

Norplant®, as a first-generation levonorgestrel implant and containing six capsules, has been shown to be effective as long-term contraception since more than 25 years ago. In the process, then the number of implants was reduced to two rods called Norplant-2®, which is then updated into Jadena® (in Indonesia) or Jadelle® (in America). As a country with the largest implant acceptors in the world, Indonesia has developed its own implant method consisting of two rods called Indoplant®. Currently being developed implant that consists of single rod called Monoplant®. Monoplant® is expected to be the best option because it only consists of a single rod implant that is easy to insertion and remove, effective and safe for at least three years. [Indones J Obstet Gynecol 2011; 35-1: 40-6]
High Sensitivity CReactive Protein (hsCRP) Level on Premature Rupture of Membrane (PROM) at Term Pregnancy Manoppo, Meily; Tendean, Hermie MM; Sondakh, Joice MM
Indonesian Journal of Obstetrics and Gynecology Volume. 5, No. 1, January 2017
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (85.833 KB)

Abstract

Objective: To compare the level of high sensitivity C-Reactive Protein (hs-CRP) on patients with premature rupture of membranes (PROM) at term pregnancy. Methods: The study was cross-sectional design. The data collection included age, parity, gestational age, birth weight, and APGAR score on 28 pregnant women at term pregnancy consisting of 14 subjects of Premature Rupture of Membrane (PROM) less than 12 hours and the remaining one was equal or more than 12 hours. We took blood samples from the subjects for the examination of hs-CRP level. Data were analyzed using non-parametric statistical test and processed using Statistical Package for Social Sciences (SPSS) version 20. Results: The mean hs-CRP level on PROM
Sistem Rujukan Kasus Infertilitas (Berdasarkan Faktor Risiko) SAMSULHADI, SAMSULHADI
Indonesian Journal of Obstetrics and Gynecology Volume. 31, No. 1, January 2007
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (165.693 KB)

Abstract

Tujuan: Membuat skor infertilitas berdasarkan faktor risiko, dari keluhan klinik, sehingga memudahkan sistem rujukan. Penatalaksanaan infertilitas menjadi lebih efektif dan efisien. Tempat: -- Bahan dan cara kerja: Rangkuman Kajian Pustaka. Infertilitas yang mempunyai angka kejadian sekitar 12%, merupakan masalah yang kompleks. Penatalaksanaannya memerlukan dana yang banyak, waktu yang lama, pada sisi lain umur, terutama umur isteri, sangat mempengaruhi kesuburan. Kesuburan isteri mulai menurun pada umur 30 tahun, menurun tajam setelah umur 35 tahun. Oleh karenanya bila umur isteri < 30 tahun, diberi skor 1, umur 31 - 35 tahun skor 2, dan skor 3 untuk umur isteri > 35 tahun. Hinting (2001) pada penelitiannya mendapatkan hubungan antara lama infertilitas dan angka kehamilan kumulatif dengan perawatan konvensional. Angka kehamilan kumulatif menurun bermakna pada lama infertilitas 2 tahun atau lebih. Berdasarkan hasil ini, maka skor 1 untuk lama infertilitas 1 - 2 tahun, 2 untuk > 2 tahun, dan 3 untuk lama infertilitas > 3 tahun. Sedangkan dari faktor infertilitas, faktor yang dominan adalah faktor ovulasi, tuba/peritoneum, dan faktor sperma. Secara klinis faktor ovulasi dapat diketahui dari siklus haid. Siklus haid teratur (siklus ovulasi) mempunyai skor 1, oligomenore atau perdarahan uterus disfungsi skor 2 dan amenore skor 3. Pada faktor tuba/peritoneum, terdapat dua kemungkinan penyebab, pertama adalah akibat endometriosis, dan kedua karena sisa/cacat akibat infeksi panggul, terutama penyakit hubungan seksual (PHS), ataupun pascaoperasi panggul. Secara klinis endometriosis dicurigai bila pada wanita infertil mengeluh adanya nyeri haid, nyeri panggul, nyeri sanggama ataupun adanya massa diadneksa. Sedangkan perlekatan pascainfeksi dapat dicurigai bila ada riwayat infeksi/operasi panggul. Makin sering terkena infeksi/operasi panggul makin besar kemungkinan adanya faktor peritoneum. Faktor endometriosis, diberi skor 1 bila tidak ada gejala klinik, skor 2 bila ada satu macam keluhan nyeri, dan skor 3 bila ada dua macam keluhan nyeri atau adanya massa adneksa. Kecurigaan perlekatan pascainfeksi, skor 1 bila tidak ada riwayat infeksi/operasi panggul, skor 2 bila ada riwayat satu kali, dan skor 3 bila ada riwayat 2 kali atau lebih. Faktor infertilitas terakhir adalah faktor sperma. Normozoospermia, diberi skor 1. Skor 2 bila ada kelainan salah satu dari densitas antara 10 - 20 juta/ml, motilitas a + b: 25 - 50%, atau morfologi 5 - 15%. Skor 3 diberikan bila didapatkan salah satu dari, densitas < 10 juta, motilitas a + b < 25%, atau morfologi normal < 5%. Pasangan infertil dikatakan risiko rendah bila, skor total: < 8, termasuk sedang bila mempunyai skor total antara 9 - 12 dan berat bila > 12. Apabila salah satu komponen skor mempunyai skor 3, maka total skor langsung menjadi > 12. Pasangan dengan risiko rendah dapat ditangani di pusat pelayanan kesehatan primer, risiko sedang sebaiknya ditangani di pusat pelayanan kesehatan sekunder, dan tertier untuk yang risiko berat. Kesimpulan: Skor infertilitas ini cukup sederhana, memudahkan sistem rujukan bagi semua pihak yang terkait, mulai dari dokter umum sampai dokter spesialis, ataupun oleh paramedik untuk konseling pada pasangan. [Maj Obstet Ginekol Indones 2007; 31-1: 49-57] Kata kunci: skor infertilitas, rujukan infertilitas
Total Serum Level of Calcium and Ion Calcium is Lower in Hypotonic Uterine Inertia Wattimury, Josef
Indonesian Journal of Obstetrics and Gynecology Volume. 1, No. 3, July 2013
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (90.642 KB)

Abstract

Objectives: To know the correlation between total and ion serum calcium level with the uterine contractility of laboring patient. Methods: This is a cross-sectional analytic correlative study measuring the strength of correlation of total and ion calcium serum level between groups with hypotonic uterine inertia - and normal labor. Each group consists of 20 subjects who met inclusion criteria and presented to Dr. Hasan Sadikin Hospital in August - September 2012. Statistical analysis was performed by using Eta (η) coefficient. Results: Mean total calcium serum level on hypotonic uterine inertia is 6.66 mg/dl, while mean of total calcium serum level on normal labor is 8.56 mg/dl, with Eta (η) correlation coefficient 0.721. Mean ion calcium serum level on hypotonic uterine inertia is 4.14 mg/dl, while mean of total calcium serum level on normal labor is 4.92 mg/dl, with Eta (η) correlation coefficient 0.802. Conclusion: Total serum level of calcium and ion calcium in hypotonic uterine inertia is lower than the level of which in normal labor. There is a strong correlation between total and ion serum calcium level with uterine contractility, the Eta (η) correlation coefficient are 0.721 and 0.802 respectively. [Indones J Obstet Gynecol 2013; 1-3: 145-8] Keywords: hypotonic uterine inertia, ion serum calcium level, normal labor, total serum calcium level
Serum Malondialdehyde Level as a Risk Factor for Threatened Abortion Sutama, Gusti N; P Surya, I Gede
Indonesian Journal of Obstetrics and Gynecology Volume. 3, No. 1, January 2015
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (129.926 KB) | DOI: 10.32771/inajog.v3i1.19

Abstract

Objective: To determine the role of serum malondialdehyde level as a risk factor for threatened abortion. Method: Our study was a case‐control study. We examined 60 pregnant women as our subject, 30 subjects with threatened abortion as cases and 30 subjects with normal pregnancy as control group. Serum levels of malondialdehyde of each woman was examined in the Biochemistry Laboratory Faculty of Medicine Gadjah Mada University in Yogyakarta. We tested the normality of our data using Kolmogorov‐ Smirnov test, and analysis was then performed using independent sample t‐test. To determine the relationship of serum malondialdehyde with threatened abortion, Chi‐Square test was used. Result: From this study we found that the average serum malondialdehyde level in threatened abortion was 1.33K0.11 nmol/ml, while the average level of serum malondialdehyde in normal pregnancy was 1.03K0.10 nmol/ml. The analysis using independent t‐test shows that the average serum malondialdehyde level on the two groups was significantly different (p=0.001). Based on the cut‐off value of 1.12 nmol/ml, we found that the relative risk of threatened abortion is 29.57 times (95% CI=6.85‐127.64, p=0.001) in those with a high level of serum malondialdehyde. Conclusion: The serum malondialdehyde level in threatened abortion was significantly different compared to normal pregnancy. A high level of serum malondialdehyde in pregnancy was a risk factor for threatened abortion. Keywords: malondialdehyde, normal pregnancy, threatened abortion
Correlations of Chronic Periodontitis with Preeclampsia and Fetal Birth Weight Yoseffin, Octaviana
Indonesian Journal of Obstetrics and Gynecology Volume. 35, No. 3, July 2011
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (48.706 KB)

Abstract

Objective: Preeclampsia is the main cause of maternal and perinatal mortality and morbidity one of which low birth weight. The cause of preeclampsia is multifactorial, and one of them is infection. High periodontal incidence is found in preeclampsia patients. This study is intended to find correlations between chronic periodontitis with preeclampsia and fetal birth weight. Method: The study was held in RS Dr. Hasan Sadikin Bandung, RSUD Astana Anyar and RSUD Ujung Berung in December 2010 - February 2011 using case-control study design in two groups,with 26 subjects in each group. The subjects were recorded on age, parity, gestational age, diagnosis, fetal birth weight, and periodontal status. Statistical analysis were performed using chi square test and Rank Spearman’s correlation test. Result: The characteristics of study subjects in both groups show no significant difference (p > 0.05). In the preeclampsia group, periodontitis incidence is higher which is 19 (73.08%) compared to control group which is 12 (46.15%). Based on chi square method, there is a significant correlation between periodontitis and preeclampsia with odds ratio value of 3.17 (p = 0.048; p < 0.05; 95%CI (1.19 - 8.41). Based on Rank-Spearman correlation test, there is a moderate negative correlation between periodontitis severity and with fetal birth weight with rs value of = - 0.423 and a p value of 0.002. Conclusion: Chronic periodontitis incidence is higher in preeclampsia group compared to control group. There’s a moderate negative correlation on periodontitis severity with fetal birth weight. The more severe the periodontitis, the lower the fetal birth weight. [Indones J Obstet Gynecol 2011; 35-3: 105-9] Keywords: periodontitis, preeclampsia, fetal birth weight
Inkontinensia urin pada perempuan menopause SUPARMAN, E.; ROMPAS, J.
Indonesian Journal of Obstetrics and Gynecology Volume. 32, No. 1, January 2008
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (148.056 KB)

Abstract

Tujuan: Memperlihatkan kaitan kejadian terjadinya Inkontinensia urin pada perempuan menopause serta jenis-jenis inkontinensia yang dialaminya serta prosedur penatalaksanaannya. Tempat: Bagian Kebidanan dan Kandungan Universitas Sam Ratulangi, Rumah Sakit Umum Prof. Dr. R.D. Kandou, Manado - Indonesia. Rancangan/rumusan data: Tinjauan literatur. Kesimpulan: Kejadian Inkontinensia pada perempuan menopause ter-jadi terutama karena kelemahan dari otot dasar pelvis. Di samping itu juga dipengaruhi oleh perubahan fungsi dan struktur dari kandung ke-mih dan uretra. Proses ini terutama diakibatkan oleh karena proses penuaan dari ovarium sehingga terjadi penurunan produksi estrogen. Estrogen melalui reseptor α dan β mempengaruhi uretra dan kandung kemih. Penurunannya mengakibatkan uretra menjadi kaku dan tidak elastis. Sehingga sukar untuk menutup dengan sempurna. [Maj Obstet Ginekol Indones 2007; 32-1: 48-54] Kata kunci: inkontinensia urin, menopause, estrogen, uretra, kandung kemih

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