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INDONESIA
Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia)
Published by Perkumpulan Obstetri dan Ginekologi Indonesia
ISSN : 23386401     EISSN : 23387335     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
The Indonesian Journal of Obstetrics and Gynecology is an official publication of the Indonesian Society of Obstetrics and Gynekology. INAJOG is published quarterly.
Arjuna Subject : -
Articles 1,760 Documents
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Calcium Level is Lower in Women with Premenstrual Syndrome Pambudi, Maria F.J.
Indonesian Journal of Obstetrics and Gynecology Volume. 37, No. 2, April 2013
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To know the relationship of calcium serum levels with the incidence of Premenstrual Syndrome (PMS). Methods: Study subject that fulfil inclusion criteria were asked to fill questionnaires and venous blood sample was taken to measure calcium serum levels. The data is processed and analyzed statistically. Result: The study was conducted on 45 women aged 20-35 years old. Groups of women with PMS found calcium levels between 8.50 to 9.40 mg/dl. Cut off point levels of calcium for PMS incidence was 9.40 mg/dl with 90.9% sensitivity, 75.0% specificity, and accuracy of 86.7%. Conclusion: Women with PMS have lower calcium levels compared to women without PMS. Calcium levels significantly associated with incidence of PMS. [Indones J Obstet Gynecol 2013; 37-2: 99-102] Keywords: premenstrual syndrome (PMS), calcium serum
Deteksi Human Papilloma Virus pada Wanita Pekerja Seks Komersial sebagai Penapisan Lesi Prakanker Serviks Uteri RETNOWATI, D.; RAUF, S.; MASADAH, R.
Indonesian Journal of Obstetrics and Gynecology Volume. 30, No. 1, January 2006
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Deteksi infeksi HPV dengan metode HC II dapat digunakan dalam upaya deteksi dini kanker serviks uteri.
Knowledge and attitude of pregnant woman toward umbilical-cord-blood collection Djuwantono, Tono
Indonesian Journal of Obstetrics and Gynecology Volume. 34. No. 2, April 2010
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: Stem cell technology from umbilical cord blood (UCB) has developed fast as health services. UCB could be used in many kinds of disease. Private UCB bank has been operated in many places all over Indonesia. There’s a need for research to evaluate the knowledge and attitude of pregnant woman towards the act of collecting UCB. Method: This is a cross-sectional study base on question-naire given to 163 pregnant women in three private hospitals in the Bandung City from September - November 2009. The result was analyzed with Rank-spearman correlation and Kruskal-Wallis chisquare. Result: Most respondent were 20 - 29 years old pregnant women (54.6%), with educational level of strata-1 (S-1) (41.1%), with monthly income within 5 - 10 million rupiah (35.6%). This is the second pregnancy or more (42.9%), with gestational age less than 24 weeks (61.3%) and variative obstetric history (59.5%). The average level of knowledge was poor and attitude scale was uncertain (3.4). There is a significant correlation between age (p = 0.008%; CI 95%), level of education (p = 0.0001; CI 95%) and knowledge. There is a significant correlation between gestational age and attitude (p = 0.003; CI 95%). Respondent’s level of knowledge also has a significant correlation with attitude (τs = 0.421; p = 0.0001; CI 95%). Conclusion: This study described the respondent’s poor knowledge will influence their attitudes toward UCB collection, so it is necessary for disseminating more information on UCB as an effort to get better research result on UCB. [Indones J Obstet Gynecol 2010; 34-2: 97-100] Keywords: knowledge level, attitudes, collecting UCB, pregnant woman, the Bandung city
Contraception as an Important Entry Point in Accessing an Integrated Reproductive Health Care: Evidence From Three Provinces in Indonesia DJAJADILAGA, DJAJADILAGA
Indonesian Journal of Obstetrics and Gynecology Volume. 31, No. 4, October 2007
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Tujuan: Mencari fakta dari studi fisibilitas/studi kelayakan penggunaan kontrasepsi (pelayanan KB) sebagai entri poin aplikasi pelayanan kesehatan reproduksi terpadu di Indonesia. Bahan dan cara kerja: Data dikumpulkan dari tahun 2001 hingga 2004 di tiga kota dengan tiga propinsi yang berbeda, menggabungkan observasi terhadap peningkatan kemampuan konseling dan pemeriksaan klinis secara keseluruhan dengan menggunakan dokumentasi berbasis komunitas dari kegiatan outreach (outreach education) terhadap komunitas target. Target komunitas pertama yaitu para pekerja pabrik muda dan tidak menikah di Batam, Provinsi Riau; kedua, perempuan perajin gerabah (pembuat barang-barang tembikar) di Pulau Lombok; dan ketiga ibu rumah tangga yang tinggal di pemukiman kumuh di antara dua wilayah pelacuran di Surabaya, Provinsi Jawa Timur. Di setiap tempat, studi dilakukan bersama organisasi mitra yang berbeda, seperti: Yayasan Mitra Kesehatan dan Kemanusiaan (Batam), Pusat Informasi Kesehatan dan Perlindungan Keluarga (Lombok) dan Yayasan Hotline Surabaya. Hasil: Di Batam, outreach mencakup 3.740 orang dalam 237 kunjungan klinis. Di Lombok menjangkau 1.502 perempuan dalam 183 pelayanan klinis. Surabaya, Jawa Timur, jumlah perempuan yang terjangkau sebanyak 1.313 orang dalam 869 pemeriksaan kesehatan reproduksi. Kesimpulan: Kontrasepsi sangat efektif sebagai entri poin sebelum menyentuh isu sensitif seperti tentang Infeksi Saluran Reproduksi/Infeksi Menular Seksual (ISR/IMS), masalah psikologi remaja (pacaran, perilaku berisiko, dan kehamilan yang tidak direncanakan). Hasil studi memperlihatkan bahwa faktor eksternal berpengaruh pada fisibilitas/ kelayakan pilot project di masa mendatang. Penjelasan tentang faktorfaktor eksternal tersebut akan dijelaskan pada paper lengkap. [Maj Obstet Ginekol Indones 2007; 31-4: 236-42] Kata kunci: kontrasepsi, kesehatan reproduksi
Expression of B-Cell Lymphoma Protein-2 (Bcl-2) and Caspase-3 are Related with Ovarian Cancer Budiana, I Nyoman G.
Indonesian Journal of Obstetrics and Gynecology Volume. 2, No. 1, January 2014
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To determine the expression of Bcl-2 and caspase-3 and their relationship with ovarian cancer. Method: This study was a cross-sectional study. Speciment was tissue sample from ovarian cancer patients collected from parafinblock to determine the Bcl-2 and caspase-3 expression and demographic data obtained secondary from patients medical records. Expression of Bcl-2 and caspase-3 was examined by immunohistochemistry under light microscope with 400x light power field. The result was recorded as negative when the protein was expressed in 10% or less of cells and as a positive when the protein was expressed in more than 10% of cells. Result: A total of 45 samples was included as research subjects. 31 of 45 subjects showed the expression of Bcl-2 positive (68.9%), while the positive expression of caspase-3 was presented in 20 subjects (44.4%). There was a relationship between the expression of Bcl-2 with the expression of caspase-3 in ovarian cancer patients (p=0.002; Lambda=0.4). There was also a negative relationship, where the subjects with positive expression of Bcl-2 showed negative expression of caspase-3. In contrast, subjects with negative expression of Bcl-2 showed positive expression of caspase-3. Conclusion: There was a significance relationship between the expression of Bcl-2 with the expression of caspase-3 in ovarian cancer patients. [Indones J Obstet Gynecol 2014; 2-1: 33-39] Keywords: Bcl-2 expression, caspase-3 expression, ovarian cancer
CC-Human Menopausal Gonadotropin Combined with Growth Hormone in Mini-stimulation Protocol could Improve Clinical Outcome in Poor Ovarian Responders Polim, Arie A; Sini, Ivan R; Anwar, Indra NC; Pradana, Aryando; Kurniawati, Kurniawati; Fani, Erliana
Indonesian Journal of Obstetrics and Gynecology Volume. 3, no. 2, April 2015
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (19.045 KB) | DOI: 10.32771/inajog.v3i2.43

Abstract

Objective: To investigate the role of CC-highly purified Human Menopausal Gonadotropin (hpHMG) and Growth Hormone (GH) in mini-stimulation protocol to improve outcome in poor ovarian responders (POR). Method: All patients were given clomiphene citrate 150 mg from day 3 to day 7 of menstrual cycle followed by 150 IU hpHMG daily from day 8 until ovulation trigger. Two groups were observed where one group received GH and the other arm did not. In the GH group, 8 IU of GH were given from day 1 of stimulation until stimulation was stopped. GnRH antagonist was used to suppress ovulation. Result: Among 51 eligible women, 29 patients with GH and 22 patients without GH, no difference was observed in the number of oocytes retrieved (2.21 versus 2.64) and the number of embryos transferred (1.24 versus 1.68) in the GH group versus the group without GH, respectively. Total clinical pregnancy rate was 17.6%. No significant difference in pregnancy and ongoing pregnancy rate in both groups (17.2% versus 18.2%) and (13.8% versus 13.6%), respectively. In patients older than 40 years old, GH showed a 4-fold likelihood in producing top quality embryos (44.8% vs 13.6%, OR=3.6, p=0.05). Conclusion: CC-HMG regimen in mini-stimulation protocol is an effective option in poor responders. Additional GH in ministimulation program provided a higher number of top quality embryos in women older than 40 years old, although there were no difference in clinical or ongoing pregnancy rate. Keywords: CC-HMG, growth hormone, IVF, mini-stimulation protocol, poor ovarian responders
Clinical and Laboratory Predictors of Deep Vein Thrombosis in Ovarian Malignant Tumor Kusuma, Fitriyadi; Sitorus, Christina
Indonesian Journal of Obstetrics and Gynecology Volume. 5, No. 3, July 2017
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (107.312 KB) | DOI: 10.32771/inajog.v5i3.548

Abstract

Objective: To investigate the clinical and laboratory predictors of symptomatic deep vein thrombosis (DVT) in ovarian malignant tumor. Methods: One hundred sixteen patients with suspected ovarian malignant tumor were recruited. Age, body mass index (BMI); D-dimer, fibrinogen, thrombocyte level, comorbid, tumor diameter, staging, distant metastasis, ascites, histopathology, length of surgery, blood loss and transfusion were recorded. Results: Incidence of symptomatic DVT was 16.5% and 88.2% cases occurred before surgery. No case of symptomatic DVT during postoperative care was found. Predictors of DVT were distant metastasis (OR 28.99; 95% CI 3.83-219.52, BMI ≥ 22.7 kg/m2 (OR 15.52, 95% CI 2.24-107.37), D-Dimer ≥ 1700 mg/ml (OR 13.30, 95% CI 2.40- 73.84), advanced stage (OR 6.66; 95% CI 1.05-42.27), epithelial tumor (OR 6.5; 95% CI 0.34-125.75), tumor’s diameter ≥ 18.25 cm (OR 2.36, 95% CI 0.48-11.54), and comorbidity (OR 2.49, 95% CI 0.53-11.66). Prediction score of DVT were score 3 for distant metastasis, BMI ≥ 22.7 kg/m2, D-Dimer ≥ 1700 mg/ml, score 2 for advanced stage, score 1 for tumor diameter ≥ 18.25 cm, comorbid, epithelial tumor and score 0 for the absence of variables or its value less than the cut off. Total score ≥ 8 of 14 is the least score which has a good predictive value for DVT with AUC 0.92, 95% CI 0.86-0.92, probability 86.46%. Conclusion: Distant metastasis and D-dimer are independently associated with the development of DVT in ovarian malignant tumor. [Indones J Obstet Gynecol 2017; 5-3: 180-184] Keywords: deep vein thrombosis, D-dimer, ovarian malignant, tumor predictor
Neonatal Haemoglobin and Haematocrit Level on Delayed Cord Clamping Astrianti, LitaLIta R.
Indonesian Journal of Obstetrics and Gynecology Volume. 36, No. 1, January 2012
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objectives: To assess neonatal haemoglobin and haematocrit level during delayed cord clamping on normal delivery. Methods: This was a randomised control trial with simple random sampling method. During March until June 2011, we collected blood sample from venous umbilical cord on newborn baby. Twenty babies were assigned to the first group, of which the clamping of the umbilical was delayed until 2 minutes (DCC). The other 20 babies were assigned to the second group, of which the clamping of the umbilical was performed as early as 10 second (ECC) after delivery of the whole body of the baby. The haemoglobin and haematocrit level was noted and compared between two groups using Mann-Whitney U test in SPSS 16 for Windows. Result: There were no difference on maternal characteristic between two groups, except for the maternal education and maternal economic status. The median neonatal haemoglobin level on DCC group was 15.77 g/dl and on ECC group was 14.36 g/dl. There was statically significant higher neonatal haemoglobin level on DCC group (p=0.005). The median neonatal haematocrit level was 44.1% on DCC group and was 43.35% on ECC group. There was no difference on neonatal haematocrit level between two groups (p=0.652). Conclusion: Delaying cord clamping until at least two minutes after delivery could increase haemoglobin level on newborn babies. Therefore, this method was suggested for every delivery in area where there is a risk of anemia in neonates such as Indonesia. [Indones J Obstet Gynecol 2012; 36-1:24-7] Keywords: delayed cord clamping, haemoglobin, haematocrit
Uji klinik kemoradiasi dibanding radiasi terhadap respons infeksi hPV dan respons klinik pada karsinoma sel skuamos serviks uteri ISKANDAR, M.; ANDRIJONO, ANDRIJONO; SUPRIANA, N.
Indonesian Journal of Obstetrics and Gynecology Volume. 32, No. 4, October 2008
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Tujuan: Untuk mengetahui apakah ekspresi virus HPV berpengaruh terhadap keberhasilan terapi Karsinoma Skuamos sel Serviks Uteri (KSSU). Penelitian ini menggunakan rancangan Studi Intervensi tanpa kontrol, kuasi eksperimental. Bahan dan cara kerja: Subjek adalah penderita KSU stadium lanjut yang mendapat kemoradiasi dan radiasi saja. Hasil: Dari 45 penderita KSU yang memenuhi syarat penelitian. Dua puluh tujuh penderita mendapat Kemoradiasi sedangkan yang hanya mendapat radiasi adalah 28 penderita. Dari pemeriksaan HC-II sebelum dilakukan terapi, dari kelompok kemoradiasi hanya 1 penderita (2,7%) dengan HPV negatif, sedang kelompok radiasi saja, semua didapatkan HPV positif sebelum dilakukan terapi. Dari kelompok kemoradiasi 8 penderita ( 29,6%) didapatkan parsial respons, sedangkan 7 penderita (25%) dengan parsial respons dari kelompok radiasi saja. Setelah terapi, 12 penderita (42,9%) didapatkan HPV masih positif pada kelompok radiasi saja, dibandingkan 6 penderita (22,2%) dari kelompok kemoradiasi. Dari kelompok persistensi HPV ini didapatkan 4 penderita (22,2%) dengan parsial respons dibandingkan 11 penderita (29,7%) dari kelompok HPV negatif pascaterapi. Kesimpulan: Ada kecenderungan kemoradiasi lebih punya pengaruh terhadap persistensi HPV. 22,2% penderita pada kelompok kemoradiasi mempunyai persistensi HPV dibandingkan 42,9 % pada kelompok radiasi saja. Secara statistik perbedaan ini tidak bermakna (P
Human Papillomavirus Genotypes and its Prevalence in Normal Population Utami, Tofan W
Indonesian Journal of Obstetrics and Gynecology Volume. 2, No. 4, October 2014
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (112.681 KB) | DOI: 10.32771/inajog.v2i4.410

Abstract

Objective: Over 200 types of human papillomavirus (HPV) have been recognized on the basis of DNA sequence. Multiple infection is more prone to be persistent than single infection. The purpose of this study is to assess the variation of HPV types and their prevalence among negative VIA as normal population in Indonesian women. Method: We processed cervical swabs from 1,214 patients with negative VIA. HPV DNA and its genotypes were detected using PCR based INNO-Lipa HPV DNA test. We also classified whether each infection is single or multiple. Result: From 1,214 women with negative VIA, 39 (3.21%) samples were positive for HPV DNA. Among them, we detected 19 types of HPV, consisting of 13 types of high-risk HPV, 5 types of low-risk HPV, and 1 type of unknown HPV (type X). The most prevalent type was HPV type 52 (18.31%), followed by type 39 and X with the same proportion (9.86%), and HPV type 16, 18, and 74 (each 8.45%). Of the total 39 HPV-positive samples, 17 (43.6%) showed multiple-type infection and 22 (56.4%) showed single-type infection. The majority of single infection involves high-risk-HPV. The remaining were type 6, 44, 18, 51 and 66, with each single-type infection showing a prevalence of 4.54%. Conclusion: Our study shows that single HPV infection among the negative VIA population are dominated by high-risk type HPV (types 52, 39, 16, and 18). Single infection was more often encountered than multiple infection. [Indones J Obstet Gynecol 2014; 4: 211-215] Keywords: HPV DNA, HPV genotypes, multiple infection, negative VIA, single infection

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