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Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia)

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Published by Perkumpulan Obstetri dan Ginekologi Indonesia

ISSN : 23386401 EISSN : 23387335 DOI : -

Core Subject : Health,

Health Professions Medicine & Pharmacology Public Health

The Indonesian Journal of Obstetrics and Gynecology is an official publication of the Indonesian Society of Obstetrics and Gynekology. INAJOG is published quarterly.

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Articles 1,760 Documents

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The Number of LH Receptor could Predict the Success of Oocyte Maturity in the Process of In Vitro Maturation Amansyah, Adek
Indonesian Journal of Obstetrics and Gynecology Volume. 1, No. 4, October 2013
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Objective: To evaluate the relationship between the number of LH receptor and the success of oocyte maturity in the process of in vitro maturation (IVM). Method: This experimental study was conducted in the Permata Hati Infertility Clinical Laboratory, Dr. Sardjito General Hospital, Yogyakarta, with the samples of 300 oocytes obtained through collecting immature cowâs oocytes from the abattoir and grouped the oocytes into 3 (three) groups based on the pattern of oocyte cumulus cells on the vesicle germinal stage 2 - 8 mm with three layers of cumulus cell. The sample of the cumulus cells from these three groups were taken and the LH receptor examination was done with immunohistochemistry. After that, the IVM process was performed to the three groups and its development for 24 hours was evaluated. Its maturation quality was evaluated with the emergence of the first polar body (1PB) and compared to the other groups and related to the number of LH receptor in the three groups. Result: The result of this study indicated that the oocyte cumulus cells showed a difference of function during IVM process. The maturity rate in this study showed that the number of LH receptor was related to the morphological pattern of oocyte cumulus cells with oocyte maturity. The maturity of the cumulus cells which 100% covered the oocyte was higher than that of the cumulus cells which > 50% and < 30% covered the oocytes, namely, 74% compared to 60% and 12%. The result of this study also showed that the average number of LH receptors in the three groups (A, B, and C) was 183.4, 78.8, and 24.0 respectively. A significant difference was found in the three groups (p < 0.0001). When related to IVM maturity, this difference showed that the bigger number of oocyte cumulus cells influenced the oocyte maturity. Conclusion: The number of LH receptor can be used as a prediction to determine the success of oocyte maturation in the process of in vitro maturation. [Indones J Obstet Gynecol 2013; 1-4:183-7] Keywords: IVM, LH receptor, oocyte cumulus cell

A Red Card for Plagiarism Gunardi, Eka R
Indonesian Journal of Obstetrics and Gynecology Volume. 3, no. 2, April 2015
Publisher : Indonesian Socety of Obstetrics and Gynecology

N/A

Evaluation of the Accuracy of Human Kallikrein6, Cancer Antigen125, and Human Epididymis 4 in Predicting Ovarian Cancer Wenas, Yongki; Suwiyoga, Ketut; Sanjaya, I Nyoman H
Indonesian Journal of Obstetrics and Gynecology Volume. 5, No. 2, April 2017
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objective: To evaluate the accuracy of hK6, HE4, and CA125 in predicting the malignancy of ovarian mass. Methods: The design of this study was cross-sectional. This study was conducted in the Obstetrics and Gynecology Clinic, Sanglah Hospital, Denpasar, between the period of September 2014 and August 2016. Samples were all patients with ovarian tumors who underwent surgery at Sanglah Hospital, Denpasar. Data analysis was performed using McNemar and chi square test in SPSS for windows version 17.0. Results: 22 samples were obtained. P > 0.05 value of age and parity variables indicated no differences between the two groups. There is no accuracy differences (sensitivity, specificity, positive predictive value, negative predictive value) of hK6 compared to histopathology examination in diagnosing ovarian cancer (p = 1). There is no accuracy differences (sensitivity, specificity, positive predictive value, negative predictive value) of HE4 compared to histopathology examination in diagnosing ovarian cancer (p = 1). There is no accuracy difference (sensitivity, specificity, positive predictive value, negative predictive value) of CA125 compared to histopathology examination in diagnosing ovarian cancer (p = 0.687). Conclusion: There was no accuracy differences (sensitivity, specificity, positive predictive value, negative predictive value) found between hK6, CA125, HE4 compared to histopathology examination in predicting ovarian cancer. [Indones J Obstet Gynecol 2017; 5-2: 110-113] Keywords: cancer antigen 125, human epididymis-4, human kallikrein 6, ovarian cancer

Serum Magnesium Ion Content in 32-36 Weeks Preterm Labor Patients in Dr. Mohammad Hoesin Hospital Palembang Diani, Shanti A.
Indonesian Journal of Obstetrics and Gynecology Volume. 35, No. 4, October 2011
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Objective: To determine the average levels of serum magnesium in 32-36 weeks of preterm labor patients and to compare the average of serum level of magnesium serum in preterm delivery 32-36 weeks with an average content of magnesium ions in normal delivery. Methods: The study is an observational descriptive cross-cut design to determine level of magnesium serum at 32-36 weeks of preterm labor. Result: Samples of this study were patients with preterm labor who were treated at the Department of Obstetrics and Gynecology in Dr. Mohammad Hoesin Palembang from January 1st, 2009 until July 31st, 2010. The number of samples was 33 subjects. Most subjects were in the range of 20-35 years of age. The largest parity in the preterm group was 0, namely 14 subjects (42.5%), while in the normal pregnancy group it was 1, viz. 12 subjects (36.4%). Conclusion: Based on the results of studies, the magnesium levels of 32-36 weeks preterm labor group was lower than the normal delivery group. The average of magnesium level in preterm labor group was 1.57 Â± 0.18, while in the normal delivery group, it was 1.88 Â± 0.23. There was a statistically significant difference found on magnesium levels in both groups (p

Perbandingan Kadar Laktat Dehidrogenase pada Asites yang disebabkan Kanker Ovarium dengan Asites Nonmaligna (Laporan Pendahuluan) TANGDIALLA, A. F.; ANDRIJONO, ANDRIJONO; PRIHARTONO, J.
Indonesian Journal of Obstetrics and Gynecology Volume. 32, No. 2, April 2008
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Tujuan: Membuktikan manfaat pemeriksaan kadar LDH untuk membedakan asites maligna dengan asites nonmaligna. Tempat: Kamar operasi ginekologi bedah pusat RSUPN Dr. Cipto Mangunkusumo, poliklinik Penyakit Dalam dan ruang pera-watan Penyakit Dalam IRNA B RSUPNCM, Jakarta. Bahan dan cara kerja: Analisis potong lintang dengan membandingkan kadar LDH dalam asites kanker ovarium dengan kadar LDH dalam asites nonmaligna. Diambil sampel cairan asites pasien kanker ovarium dan asites pasien bukan kanker dengan cara paresintesis/ aspirasi saat operasi sebanyak 10 cc. Pada asites yang terkumpul, dilakukan pemeriksaan kadar LDH dengan cara enzimatik. Hasil: Data kadar LDH diperoleh dari 17 pasien kanker ovarium (delapan kasus stadium IA, 3 kasus stadium IB, 1 kasus stadium IC, dan 5 kasus stadium IIIC; delapan puluh dua persen dari kasus merupakan adenokarsinoma, sisanya 12% kasus jenis sel granulosa dan 6% kasus dengan germ cell) dan 9 pasien bukan kanker (empat kasus sirosis hepatis, 2 kasus gagal jantung, 1 kasus peritonitis tuberkulosis dan 2 kasus kista jinak ovarium) dengan karakteristik kelompok usia terbanyak 30 - 50 tahun. Didapatkan kadar LDH asites pada pasien kanker ovarium lebih tinggi secara bermakna dibandingkan dengan kadar LDH asites pasien bukan kanker (p

Hang-up IUD, New Technique for Suturing CuT-380A IUD to Uterine Fundus in Immediate Postplacental Insertion during Cesarean Delivery: Twelve Months Follow up Tjahjanto, Hary; Haryuni, Indah T
Indonesian Journal of Obstetrics and Gynecology Volume. 2, No. 3, July 2014
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objective: The aim of this study was to evaluate the effectiveness, side effects and acceptability of postplacental CuT-380A IUD insertion using new technique for suturing to uterine fundus during cesarean section (hang up technique). Method: Prospective cohort study of postplacental IUD CuT-380A insertion during cesarean delivery. Hang-up technique consists of performing a puncture in the center of the fundus wall using straight needle into the uterine cavity and subsequently using chromic catgut no. 1 to tie the IUD using anchor knot and hanging the IUD to the fundus. Our subjects were women who underwent caesarean delivery at dr. Kariadi Hospital between 1st June 2009 to 31st April 2011 and followed up at 12 months follow-up, one woman underwent IUD removal because of severe dysmenorrhea. No perforation or expulsion was reported. Conclusion: Immediate postplacental insertion of IUD CuT-380A using hang-up technique is safe and effective. Typical use effectiveness is high (Pearl Index 0.93) and there were no reported incidents of expulsion or perforation. Acceptance and continuation rate were high, 98.15% and 95.37% respectively. [Indones J Obstet Gynecol 2014; 2-31: 132-139] Keywords: anchor knots, cesarean section, hang-up IUD, postplacental IUD insertion

A Case of Prenatal Diagnosis of Trisomy 18 with Ultrasound Yusrawati, Yusrawati; Kartika, Yudha M
Indonesian Journal of Obstetrics and Gynecology Volume. 3, No. 4, October 2015
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objective: To report a case of trisomy 18 diagnosed in prenatal care. Methods: Case report. Case: A 24 years old primigravida woman was diagnosed with term pregnancy (37-38 weeks) with an intrauterine singleton live fetus with Edwards syndrome. In 15-16 weeks of pregnancy the omphalocele was discovered using ultrasound. Subsequently, amniocentesis was performed and the chromosome analysis result showed Edwards syndrome (47, XX +18). The patient chose to continue the pregnancy until term. In this patient, elective CS was performed at term pregnancy, involving teamwork between obstetrics and perinatology. A female baby was born weighing 1720 grams, 40 cm body length, and APGAR score of 5/7. The congenital anomalies discovered include umbilical hernia, rocker bottom feet, clenched hands, low set malformed ears, and a single umbilical artery. The baby was born with asphyxia, improved after resuscitation, and required treatment in the NICU. Pediatric surgeons planned umbilical hernia repair. Furthermore, because of the presence of suspected esophageal atresia, the baby was planned for gastrotomy, which was delayed because the baby was experiencing desaturation. Because of the unstable condition of the baby, echocardiography and gastrotomy were not done until the 18th day of treatment. At the 18th day, the baby’s condition deteriorated and the baby died with metabolic acidosis. Conclusion: Edwards syndrome can be diagnosed in the prenatal period by risk factors consideration, maternal serum markers, and ultrasonographic identification of organ abnormalities. [Indones J Obstet Gynecol 2015; 3-4: 234-238] Keywords: Edwards syndrome, prenatal diagnosis, trisomy 18, ultrasound

The Association of Creactive Protein Levels in Second Trimester of Pregnancy with Preeclampsia Nasruddin, Zulfaekasari; Lukas, Efendi; Malinta, Umar; Chalid, Maisuri T
Indonesian Journal of Obstetrics and Gynecology Volume 6. No. 1. January 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objective: To determine C-reactive protein in second trimesterof pregnancy women who preeclamptic and non-preeclampticwomen, and to determine the relationship between the level ofC-Reactive protein of trimester two pregnancy and preeclampsiaoccurrence.Methods: This was a prospective study conducted at the policlinicsof network of academic hospitals of the Department of Obstetricsand Gynecology of Faculty of Medicine, Universitas Hasanuddin andpoliclinic of child and mother, and some Public Health Centers inMakassar city from September 2015 - April 2016. The C-reactiveprotein 115 level of pregnant women in pregnancy age of 24-28weeks was checked, whether the subjects underwent preeclampsiauntil the childbirth process. Statistics analysis used Fisher’s exacttest and Mann Whitney test.Results: The result indicate that 9 subjects (7.8%) developedpreeclampsia and 106 subjects did not become preeclampsia. Thelevel of C-Reactive protein increased in preeclampsia group comparedto non preeclampsia group i.e 5.05  1.153 : 3.36  0.265,but statistically the result is not significant (value p>0.05).Conclusion: The average score of C-Reactive protein of preeclampsiagroup is 33.5% higher than non-preeclampsia group,even though these results cannot be used as the score to predictthe preeclampsia occurrence.Keywords: C-reactive protein, preeclampsia, second trimesterpregnancy

Embryo Quality: The Most Critical Factor for Pregnancy Rates after day-2, day-3, and day-5 of Embryo Transfer Djuwantono, Tono
Indonesian Journal of Obstetrics and Gynecology Volume. 34, No. 4, October 2010
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Objective: To determine the most critical factor on day-2, day-3, and day-5 of embryo transfer in correlation with pregnancy rates. Method: This research is a retrospective study in Aster Fertility Clinic, IVF program- Dr. Hasan Sadikin Hospital, Bandung, Indonesia. One hundred ninety five women enrolled in an IVF program conducted from March 2006 through November 2009 at the Aster Fertility Clinic. Effect of embryo-transfer day and any other factors (including quality of embryo, oocyte quantity, difficulty of embryo transfer technique, and blood or mucus contamination on the catheter) on pregnancy rate in IVF. Results: The mean age of the pregnant group was 34.65 (SD = 3.91), and the mean of the infertility period was 7.25 years (SD = 3.54). There were no siginificant differences in pregnancy rates in the day-2, day-3, and day-5 groups. The most critical factor influencing pregnancy was the total score for the quality of embryos [p = 0.001; OR (CI 95%) = 1.94 (0.91 - 4.08)]. Otherwise, the day of embryo transfer, oocyte quantity, and difficulties in embryo transfer did not affect the pregnancy rate (p > 0.05). Conclusion: Our study suggests that the total score for the quality of the embryos was the most critical factor for the success rate of pregnancy rather than the day of embryo transfer, oocyte quantity, difficulty of embryo transfer technique, or contamination of blood and mucus on the catheter. [Indones J Obstet Gynecol 2010; 34-4: 175-9] Keywords: day of embryo transfer, in vitro fertilization, quality of embryo total score, oocytes quantity, catheter contamination

Gambaran densitas mineral tulang vertebra lumbal akseptor KB suntik DMPA TAHIR, A.M.
Indonesian Journal of Obstetrics and Gynecology Volume. 33, No. 2, April 2009
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Tujuan: Dilakukan penelitian untuk menilai dampak pemakaian kontrasepsi suntik DMPA pada densitas tulang Vertebra Lumbal (VL. 1-4) pada akseptor jangka pendek pada saat sebelum suntikan ke 3-3 (minggu ke 24 atau 6 bulan) dan sebelum suntikan kelima (minggu ke 48 atau 1 tahun) dibandingkan dengan perempuan bukan akseptor sebagai kontrol dan akseptor jangka panjang (â¥ 5 tahun), dengan alat Dual Energy X-Ray Absorptiometry (DEXA). Tempat: Dilakukan di Makassar antara Januari 2006 - Maret 2007 pada 33 orang akseptor KB suntik DMPA jangka pendek (1 tahun), 31 orang akseptor suntik DMPA jangka panjang (â¥ 5 tahun), dan 33 perempuan bukan akseptor KB sebagai kontrol. Rancangan/rumusan data: Potong Lintang. Hasil: Karakteristik sampel berdasarkan umur rerata: 22,7 Â± 3,1 tahun (akseptor 1 tahun) dan 27,2 Â± 4,8 tahun (kontrol), homogen secara statistik. Sebelum perlakuan, tidak ditemukan perbedaan yang bermakna antara DMT VL. 1-4 kedua kelompok (p > 0,05). Setelah perlakuan, DMT VL. 1-4 pada akseptor 1 tahun menjadi lebih rendah dibandingkan kontrol pada semua level vertebra lumbal, dengan uji Mann Whitney menunjukkan perbedaan yang bermakna (p < 0,05). Besarnya perubahan DMT antara akseptor dan kontrol menunjukkan perbedaan yang bermakna, di mana perubahan pada akseptor (p < 0,05) bahkan pada kontrol tidak ada perubahan (0,0). Angka kejadian pada osteopenia lebih tinggi pada akseptor daripada akseptor 1 tahun dan akseptor 1 tahun lebih tinggi daripada kontrol pada pada semua level VL. Kesimpulan: Kejadian osteopenia berhubungan dengan lama pemakaian KB Suntik DMPA. [Maj Obstet Ginekol Indones 2009; 33-2: 101-7] Kata kunci: DMT vertebra lumbal, DMPA

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