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INDONESIA
Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia)
ISSN : 23386401     EISSN : 23387335     DOI : -
Core Subject : Health,
The Indonesian Journal of Obstetrics and Gynecology is an official publication of the Indonesian Society of Obstetrics and Gynekology. INAJOG is published quarterly.
Arjuna Subject : -
Articles 1,731 Documents
Abnormal Trophoblast Invasion: The Culprit of The Major Obstetrics Problems Sri Sulistyawati
Indonesian Journal of Obstetrics and Gynecology Volume 10 No. 3 July 2022
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v10i3.1801

Abstract

Nutrition versus Great Obstetric Syndrome: A Bridge too Far? T. Joewono, Hermanto
Indonesian Journal of Obstetrics and Gynecology Volume 10 No. 4 Oktober 2022
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v10i4.1856

Abstract

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Thanatophoric Skeletal Dysplasia Type 2: Diagnostic and Management Dilemmas Gezta Nasafir Hermawan; Jacobus Jeno Wibisono; Dyana Safitri Velies
Indonesian Journal of Obstetrics and Gynecology Volume 11 No. 1 January 2023
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v11i1.1598

Abstract

Abstract (English) Objective: To report a rare case of thanatophoric skeletal dysplasia type 2 that we diagnosed during prenatal period; and to provide further review of dilemmas in diagnostic methods and management, based on appropriate literatures and guidelines available. Methods: Case report Case: A 33-year old primigravida women was diagnosed with pre-term pregnancy (24th weeks of gestation) and intra-uterine singleton live fetus with thanatophoric skeletal dysplasia type 2 via ultrasonography. Pregnancy termination via elected caesarean section at 26th weeks of gestation was performed per the patient request after considering the fetus’s lethality. A female neonate was born weighing 980 grams with frontal bossing (Head Circumference: 26 cm), lower set of ears, hypertelorism, bilateral exopthalmos, short neck, rhizomelic short extremities, and narrow thorax (Thorax Circumference: 17 cm). The newborn was immediately transferred to NICU for post-natal management and observation. The newborn is in stable condition for the first several hours; nevertheless, significant destabilization occurred afterwards and the newborn deceased approximately 10 hours after birth due to cardiorespiratory failure. No further invasive resuscitative efforts and post-mortem examinations were performed on the parent’s request. Conclusion: Thanatophoric dysplasia is primarily diagnosed using ultrasonography, which has a high detection rate for both diagnosis and prognostications. Even though, There has been a dilemma in performing molecular diagnostic testing, prediction of recurrence risk in future pregnancies can be assessed with its use. Although still remains a challenge in ethical and medicolegal grounds; proper management requires holistic considerations of maternal, fetal, and perinatal aspects. Keywords: Thanatophoric, Skeletal Dysplasia, FGFR3 mutation Abstrak (Indonesia) Tujuan: Melaporkan suatu kasus langka displasia skeletal tanatoforik tipe 2 yang kami diagnosa dalam periode perinatal; serta memberikan ulasan lanjut mengenai dilema dalam metode diagnostik dan manajemen, berdasarkan literatur dan pedoman ilmiah yang tersedia. Metode: Laporan Kasus Kasus: Seorang perempuan primigravida berusia 33 tahun di diagnosa dengan kehamilan pre-term (24 minggu gestasi), janin tunggal hidup intrauterin dengan displasia skeletal tanatoforik tipe 2 via ultrasonografi. Terminasi kehamilan dengan Sectio Caesarea dilakukan atas permintaan pasien setelah mempertimbangkan letalitas janin. Lahir bayi perempuan berat 980 gram, dengan ‘frontal bossing’ (lingkar kepala: 26 cm), kedua telinga rendah, hipertelorisme, eksoftalmos bilateral, leher pendek, ektremitas pendek rizomelik, dan rongga dada kecil (lingkar dada: 17 cm). Bayi segera dipindahkan ke NICU untuk manajemen paska-natal dan observasi. Kondisi bayi stabil selama beberapa jam pertama; namun, ketidakstabilan yang signifikan terjadi setelah itu dan bayi dinyatakan meninggal 10 jam paska kelahiran dikarenakan kegagalan kardiorespirasi. Bayi tidak dilakukan tindakan resusitasi invasif dan pemeriksaan paska kematian atas permintaan pasien. Kesimpulan: Displasia tanatoforik dapat di diagnosa secara primer menggunakan pemeriksaan ultrasonografi (US) dengan tingkat deteksi diagnosis dan prognosis yang tinggi. Meskipun pemeriksaan diagnostik molekular masih menjadi dilema, pemeriksaan ini dapat memprediksi resiko rekurensi pada kehamilan selanjutnya. Walaupun masih merupakan suatu tantangan dalam segi etika dan medikolegal; manajemen ideal perlu mempertimbangkan secara holistik seluruh aspek yang mencakup: ibu, janin, dan paska kelahiran. Kata Kunci: Tatanoforik, Displasia Skeletal, Mutasi FGFR3 Correspondence: Gezta Nasafir Hermawan, Faculty of Medicine, Sam Ratulangi University. Email: gezta.hermawan@gmail.com
Resolution of ethical conflicts between medical indications and patient preferences in case of unmarried woman with ovarian cancer: Penyelesaian Konflik Etika antara Indikasi Medik dan Preferensi Pasien pada Kasus Perempuan yang belum Menikah dengan Kanker Ovarium Taufik S. Ismail; Putri Irmayani; Kulsum Kulsum
Indonesian Journal of Obstetrics and Gynecology Volume 11 No. 4 October 2023
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v11i1.1652

Abstract

Objectives: To resolve ethical conflicts in medical decision making in unmarried patients with a diagnosis of ovarian cancer. The ethical issue in this case is the main operative management in cases of ovarian cancer, namely removal of the uterus and both ovaries even though the patient is not married and has never been pregnant. The opportunity for patients to get pregnant no longer exists, so there is an ethical conflict between medical indications and patient preferences.Methods: This case report is about an unmarried woman 38- year with a diagnosis of ovarian cancer. This patient initially underwent right salfingooophorectomy surgery. Anatomical pathology results found adenocarcinoma serosum ovarii. The patient underwent chemotherapy for 3 cycles. Then the patient was re-operated with a planned debulking interval laparotomy.Discussion: From the aspect of patient indications, the results of combination treatment between surgery and chemotherapy have shown a marked increase in the survival rate of patients in five years. The choice of performing a debulking interval laparotomy is a difficult choice. The patient's preference to get pregnant will be difficult to accept, but it can be accommodated by improving the quality of life and paying attention to humanism, social and cultural aspects of its contextual features.Conclusion: Clinical ethical considerations related to uterine removal in unmarried patients is a matter of debate. Clinical ethical theory namely quality of life, patient preferences, medical indications, and contextual features are beneficial in medical decision making.Keywords: debulking intervals, ethical conflicts, medical indications, ovarian cancer, patient preferences.Tujuan: Untuk menyelesaikan konflik etik dalam pengambilan keputusan medik pada pasien yang belum menikah dengan diagnosis kanker ovarium. Isu etik pada kasus ini yaitu manajemen operatif utama pada kasuskanker ovarium yaitu pengangkatan uterus dan kedua ovarium padahal pasien belum menikah dan belum pernah hamil. Kesempatan untuk pasien untuk hamil tidak ada lagi sehingga terjadi pertentangan etik antara indikasi medik dengan preferensi pasien.Metode: Laporan kasus ini tentang seorang pasien perempuan yang belum menikah, berusia 38 tahun dengandiagnose kanker ovarium. Pasien ini awalnya dilakukan operasi salfingoooforektomi kanan. Hasil patologi anatomi ditemukan adenokarsinoma serosum ovari. Pasien menjalani kemoterapi sebanyak 3 siklus. Kemudian pasien dilakukan operasi kembali yang direncanakan tindakan laparotomi interval debulking.Diskusi: Dari aspek indikasi pasien, hasil pengobatan kombinasi antara pembedahan dan kemoterapi telahmenunjukkan peningkatan survival rate yang nyata pada pasien dalam lima tahun. Pilihan melakukan tindakanlaparotomi interval debulking merupakan pilihan sulit. Preferensi pasien untuk dapat hamil akan sulit dikabulkan, namun dapat diakomodir dengan peningkatan kualitas hidup dan memperhatikan aspek humanism, sosial dan kultural pada fitur kontekstualnya.Kesimpulan: Pertimbangan etik klinik yang berhubungan dengan pengangkatan rahim pada pasien yang belum menikah merupakan masalah yang diperdebatkan. Teori etika klinis yaitu indikasi medis, preferensi, kualitas hidup dan fitur kontektual sangat membantu dalam pengambilan keputusan medis yang etis.Kata kunci: indikasi medis, interval debulking, kanker ovarium, konflik etik, preferensi pasien
Maternal and Perinatal Outcomes in Pregnancy Complicated with Pre- and Gestational Diabetes Mellitus Ayya Maheswara; Razmaeda Sarastry; Herman Kristanto; Julian Dewantiningrum; Putri Sekar Wiyati
Indonesian Journal of Obstetrics and Gynecology Volume 11 No. 1 January 2023
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v11i1.1655

Abstract

Objective: To analyze maternal and perinatal outcomes in pregnancies complicated by pre-gestational and gestational diabetes. Methods: This is an analytical observational study with a cross-sectional design. We examined 57 women, 39 of pre-gestational diabetes mellitus (PGDM) women, and 19 had gestational diabetes mellitus (GDM). The data were analyzed using the chi-square and Fisher’s exact test. Results: There were no maternal deaths in either group. Pre-eclampsia was significantly higher in the PGDM group. Perinatal deaths and asphyxia were the same in both groups. Prematurity was higher in the PGDM group. Neonates of GDM women appeared to be heavier. Intrauterine fetal death (IUFD) rates were higher in the GDM group. Congenital anomalies were found in the GDM group. Conclusion: There were differences in maternal and perinatal outcomes in both groups, namely pre-eclampsia and congenital anomaly.
Dinoprostone Gel versus Intra-cervical Foley’s Catheter for Pre-induction Cervical Ripening: An audit Dolly Chawla; Akanksha Tomar; Prachi Renjhen; neeru malik
Indonesian Journal of Obstetrics and Gynecology Volume 11 No. 1 January 2023
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v11i1.1662

Abstract

Background One of the common practices in modern obstetrical care is labour induction when foetal and maternal complications arise. We endeavoured to compare the efficacy and safety of the inexpensive mechanical method of induction Foley’s catheter to the more established pharmacological agent Intracervical Prostaglandin E2 gel Method The present prospective randomised control study was carried out on 200 women with a term singleton pregnancy in cephalic presentation, with an unfavourable cervix and a valid indication for induction of labour. The patients were randomly allocated using the chit method to either Foley’s catheter [group A, n=100] or PGE2 gel [group B, n=100] . Augmentation with oxytocin was done if required and labor was closely monitored till delivery and the perinatal outcome and maternal side effects was recorded Quantitative variables were compared using unpaired t-test/Mann-Whitney Test and qualitative variables were compared using Chi-Square test /Fisher’s exact test. Analysis was done using Statistical Package for Social Sciences (SPSS) version 21.0 RESULTThe caesarean section rate did not show a significant difference between the Foley’s group(18%) and PGE2 group(11%) The incidence of fetal distress, Meconium stained liquor and APGAR score <7 at 5 minutes was significantly with PGE2 as compared to group A. (P<.05) Incidence of hyperstimulation of uterus was reported in 6% women who received PGE2 as compared to none in Foley’s group. The induction delivery interval did not show any significant difference between the two groups. CONCLUSION In women undergoing induction of labour at term in resource constraint set ups like ours, Foley catheter is a good alternative to the more established prostaglandin E2 gel, with good efficacy and better neonatal and maternal safety profile. Keywords: cervical ripening; dinoprostone; obstetric labor, induced
Overview of S-RBD Antibody Levels After Covid-19 Vaccination in Premenopausal and Menopausal Women Juminten Saimin; Irawaty Irawaty; Nur Indah Purnamasari; Yenti Purnamasari; Sufiah Asri Mulyawati
Indonesian Journal of Obstetrics and Gynecology Volume 11 No. 1 January 2023
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v11i1.1666

Abstract

Objective: To determine the levels of S-RBD antibodies in premenopausal and postmenopausal women who received the COVID-19 vaccine. Methods: This study involved 21 premenopausal and postmenopausal women who received two doses of CoronaVac at 28 days intervals. The duration of vaccination was 4-24 weeks. This study was conducted on May–October 2021 in Kendari City, Indonesia. Blood samples were taken at a health care facility and examined at the Prodia Clinical Laboratory. Participants were healthy women, willing to participate, and signed informed consent. Participants were excluded if they had a history of COVID-19, had taken antibiotics or immunomodulators in the last 24 hours, had a history of acute/chronic inflammatory disease and malignancy, were traumatized and received monoclonal antibody therapy. Results: Participants were 52.95±7.61 years old. The duration of the second vaccination was 13.67±5.26 weeks. The lowest level of S-RBD antibody was menopause with vaccination duration <=12 weeks (185.59±112.34 U/mL), and the highest was premenopause with vaccination duration >12 weeks (257.5±3.54 U/mL). The S-RBD antibody level in premenopausal women was higher than in menopausal women at the duration of vaccination <=12 weeks (223.37±63.45 vs 185.59±112.34 U/mL) and >12 weeks (257.5±3.54 vs. 225.55±91.14 U/mL). There was no significant difference in S-RBD antibody levels between two or more groups (p>0.05). Conclusion: S-RBD antibody levels in postmenopausal women after receiving two doses of COVID-19 vaccine were lower than in premenopausal women, but the difference was not significant. S-RBD antibody levels in postmenopausal women increased with increasing duration of vaccine administration. Keywords: menopause, immune response, COVID-19 vaccine, S-RBD antibody
Factors Influencing Word-of-Mouth Behaviour at Outpatient Department YPK Mandiri Hospital, Jakarta Raissa Liem; Darrell Fernando; Innocentius Bernarto
Indonesian Journal of Obstetrics and Gynecology Volume 11 No. 1 January 2023
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v11i1.1671

Abstract

The purpose of this study was to determine the factors that influence the word-of-mouth behavior of patients seeking treatment at YPK Mandiri Hospital, Jakarta. The factors studied were doctor's expertise, doctor's communication, nursing, ancillary, and administration services, hospital reputation, and the physical structure and facilities of the hospital. Data were collected by a questionnaire distributed to patients receiving outpatient treatment. The number of samples obtained is 162 samples. A convenience sampling technique was used in this study. Data analysis was performed using the Partial Least Square-Structural Equation Modelling (PLS-SEM) approach using SmartPLS software. The results showed that doctors’ expertise, doctors’ communication, hospital reputation, and the physical structure and facilities of the hospital are related to word-of-mouth behavior. Nursing, ancillary, and administrative services are not related to word-of-mouth behavior.
Menstrual Cycle Length and Dysmenorrhea in Female Adolescents Aged 9-18 Years Agnes Monica; Lilis; Felicia Kurniawan; Astrid Fransisca Padang
Indonesian Journal of Obstetrics and Gynecology Volume 11 No. 1 January 2023
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v11i1.1674

Abstract

Abstract Objective: To determine the relationship between menstrual cycle length and dysmenorrhea in female adolescents aged 9-18 years in Sang Timur Tomang School West Jakarta. Methods: This study used a cross-sectional study approach to conduct observational analytic research. The study samples were female students aged 9-18 years in Sang Timur Tomang School. Study data were obtained through the Verbal Multidimensional Scoring System (VMSS) questionnaire in Indonesian. The Chi-square test of independence was used to determine the relationship between menstrual cycle length and dysmenorrhea. Results: From a total of 137 respondents, 38% have abnormal menstrual cycle length. Eighty-two-point-seven percent of respondents who have abnormal menstrual cycle length experienced dysmenorrhea, and 17,3% of participants who have abnormal menstrual cycle length did not experience dysmenorrhea. Chi-square test results showed a significant relationship between menstrual cycle length and dysmenorrhea in female adolescents aged 9-18 years in Sang Timur Tomang School West Jakarta (p = 0,005). Conclusion: There is a significant relationship between menstrual cycle length and dysmenorrhea in female adolescents aged 9-18 years in Sang Timur Tomang School West Jakarta. Keywords: female adolescents, dysmenorrhea, menstrual cycle, menstrual cycle length
Placenta Acreta Yudianto B Saroyo
Indonesian Journal of Obstetrics and Gynecology Volume 11 No. 1 January 2023
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v11i1.1924

Abstract


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