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INDONESIA
Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia)
Published by Perkumpulan Obstetri dan Ginekologi Indonesia
ISSN : 23386401     EISSN : 23387335     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
The Indonesian Journal of Obstetrics and Gynecology is an official publication of the Indonesian Society of Obstetrics and Gynekology. INAJOG is published quarterly.
Arjuna Subject : -
Articles 1,760 Documents
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The Salivary Estriol Level was Higher in Preterm Delivery Compared to that in Preterm Pregnancy Purba, Erwin
Indonesian Journal of Obstetrics and Gynecology Volume. 36, No. 2, April 2012
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (97.072 KB)

Abstract

Objective: To know the difference of salivary estriol level between patients with preterm birth and preterm pregnancy of 32-36 weeks and to determine the correlation between the level of estriol in saliva and the incidence of preterm delivery. Methods: This research was a cross-sectional studies of 80 patients in Dr. Hasan Sadikin Hospital and its networks. The subjects are 40 patients in labor and 40 patients in preterm pregnancy, that met the inclusion criterias during the period September 2011 to November 2011. We took the salivary sample and examine the level of estriol. The data were analyzed by Shapiro-Wilk and Mann Whitney test. Result: The study found that the difference of salivary estriol levels in preterm labor and preterm pregnancy groups was statistically significant (p
Perbandingan kadar regulatory T-cells antara kehamilan normal dan abortus SUHEIMI, I.
Indonesian Journal of Obstetrics and Gynecology Volume. 33, No. 1, January 2009
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (134.45 KB)

Abstract

Tujuan: Untuk mengetahui peran Treg dalam kelangsungan kehamilan dengan mengukur kadar Treg dalam kehamilan normal di bawah 20 minggu, mengukur kadar Treg dalam kejadian abortus dan membandingkan kadar Treg dalam kehamilan normal di bawah 20 minggu dan dalam kejadian abortus. Tempat: RSUPN Dr. Cipto Mangunkusumo, baik di IGD lantai 3 maupun poliklinik Obstetri dan Ginekologi. Bahan dan cara kerja: Penelitian bersifat penelitian observasional tanpa intervensi berupa studi comparative cross-sectional, dilakukan pada kelompok perempuan hamil normal dan kelompok perempuan yang mengalami abortus yang datang ke tempat penelitian. Pengumpulan data dilakukan sejak subjek penelitian datang di IGD lantai 3 atau poliklinik Obstetri dan Ginekologi RSCM. Jika kasus sesuai dengan kriteria penerimaan dan penolakan maka dilakukan informed consent untuk mendapat persetujuan penelitian. Diambil darah vena pasien sebanyak 50 mikroliter dan dimasukkan ke dalam alat flowcytometry dengan reagen spesifik untuk pemeriksaan CD45 (Per-CP- 347464), CD4 (SIPC-340133) dan CD25 (PE-341009) untuk kemudian dihitung jumlah Treg dengan sistem lyse no washed menggunakan software cellquest pro. Output dari alat flowcytometry tersebut kemudian dicatat. Pasien dengan kehamilan normal (kelompok kontrol) di follow-up sampai kehamilannya mencapai 20 minggu untuk memastikan tidak terjadinya abortus sampai batas waktu tersebut. Jika pasien dengan kehamilan normal pada saat pemeriksaan ternyata mengalami abortus di bawah 20 minggu, maka pasien tersebut akan dimasukkan ke dalam kelompok dengan kejadian abortus (kelompok kasus). Hasil: Pada uji statistik perbandingan rerata persentase sel CD45 didapatkan bahwa tidak terdapat perbedaan yang bermakna secara statistik antar kedua kelompok, di mana rerata kelompok kasus adalah 10,96 ± 6,57% sel dibandingkan dengan rerata 9,60 ± 5,30% sel pada kelompok kontrol dengan p = 0,610. Pada perbandingan kadar Treg dari hasil uji statistik didapatkan Median pada kelompok kasus (2,45 sel/μl) dibandingkan dengan Median kelompok kontrol (2,53 sel/μl) tidak menunjukkan perbedaan yang bermakna secara statistik dengan p = 0,946 (uji korelasi Mann-Whitney). Kesimpulan: Penelitian ini mendapatkan bahwa tidak terdapat hubungan antara kadar Regulatory T-cells (Treg) dengan kejadian abortus. [Maj Obstet Ginekol Indones 2009; 33-1: 20-7] Kata kunci: regulatory T-cells, Treg, abortus
Social Support and Postpartum Depression in Human Immuno Deficiency Virus (HIV) Patients Saroyo, Yudianto B.
Indonesian Journal of Obstetrics and Gynecology Volume. 2, No. 3, July 2014
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (19.045 KB) | DOI: 10.32771/inajog.v2i3.418

Abstract

Objective: To evaluate the relationship between social support given to HIV patients with the incidence of postpartum depression. Method: All HIV patients who had delivery in Dr. Cipto Mangunkusumo hospital and Prof. dr. Sulianti Saroso hospital during the period of October 2012 to March 2013 were enrolled as research subjects. We performed depression screening with the Edinburgh Postnatal Depression Scale (EPDS) and to measure the social support provided by Social Support Questionnaire/Kuesioner Dukungan Sosial (KDS). Statistical analysis was done using Fisher’s exact test, Chi-square and unpaired t-test. Result: We found a total of 34.1% of subjects who experienced postpartum depression, in which 40% did not received proper social support. Considering the demographic characteristics of the subjects who experienced depression, 70% was in age group 20-35 years, 56.7% of subjects had low education level and 70% was primiparous. Conclusion: Social support has a protective effect towards postpartum depression in HIV patients. [Indones J Obstet Gynecol 2014; 3: 117-120] Keywords: Edinburgh postnatal depression scale, HIV, (kuesioner dukungan sosial), postpartum depression, social support
The Serum Level of Vascular Endothelial Growth Factor (VEGF) is Declined after Paclitaxel-Carboplatin Combined Chemotherapy Treatment on Epithelial Ovarian Cancer Abdullah, Amelia
Indonesian Journal of Obstetrics and Gynecology Volume. 36, No. 3, July 2012
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To assess the effect of Paclitaxel-Carboplatin combination on epithelial ovarian cancer by studying the changes in VEGF serum levels after receiving 3 series of chemotherapy. Methods: This was a cohort study conducted at several teaching hospitals in Obstetrics and Gynecology Department of the Faculty of Medicine, Hasanuddin University from April 2011 to March 2012. The subjects were patients with ovarian cancer who met the inclusion criteria and had undergone surgery. The clinical staging was determined with 2009 FIGO criteria. They went through histopathology examination to determine the histological type and cell differentiation of the lesion. They also went through combined chemotherapy of Paclitaxel and Carboplatin. The data were analyzed with paired t-test. Results: The study reveals that out of 30 cases of ovarian cancer who received a combination chemotherapy, most were < 45 years of age (53.33%), nulliparous (46.7%), serosum type (53.3%), with moderate differentiation (36.7%), and in advanced stage (73.3%). The VEGF serum level after 3 series of chemotherapy was lower than before (the average value: 294.67 vs 572.77 ng/ml). There was a significant change in VEGF serum level after receiving chemotherapy (p=0.000). The VEGF serum level of advanced-stage and early stage epithelial ovarian cancer after chemotherapy decreases significantly (p=0.000 and p=0.011). The advanced-stage cases showed more responses to chemotherapy than the early-stage did. There was a tendency that adenocarcinoma serosum type was more responsive to the therapy than mucinosum type (p=0.000 vs 0.003). Conclusion: There is no difference in VEGF serum level based on cell differentiation but there is a tendency that well and moderate differentiated cells have a greater change than the poor differentiated cells (p=0.003, p=0.003 vs p=0.019). [Indones J Obstet Gynecol 2012; 36-3: 135-9] Keywords: carboplatin, epithelial ovarian cancer, paclitaxel, VEGF
Profile of pregnant women with tuberculosis at the tuberculosis policlinic of the eradication of tuberculosis, Tuberculosis Foundation, Baladewa Central Jakarta Maharani, Laksmi
Indonesian Journal of Obstetrics and Gynecology Volume. 33. No. 4, October 2009
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To know profile of pregnant women with tuberculosis at PPTI Baladewa polyclinic Jakarta, to evaluate impacts of tuberculosis medicinal treatment on pregnancy and to know the obstacles of pregnant women to look for tuberculosis treatment. Methods: Subjects were all pregnant women with tuberculosis and received tuberculosis treatment at polyclinic of PPTI Baladewa from January 2006 - December 2007. We reviewed medical record and did home visitation to fill questioners. Results: All subjects were in reproductive age and most of all were low socio-economic group. Pulmonary tuberculosis was found in 88.2% cases and Extrapulmonary tuberculosis in 11.8% cases. We found 29.4% relapse cases and 11.8% multi-drug resistance. Sputum examination with a smear positive for acid fast-bacillus was found in 52.9% cases. There was abnormality for all chest x-rays. The third most frequently symptoms were cough more than two weeks (88.2%), weight loss (88.2%) and anorexia (82.4%). Average time for the patients to look for treatment was 50.71 ± 31.2 days. The patients need more time because most of the symptoms are also present in pregnancy, the patients know absolutely nothing about TB and healthcare provider didn’t examine carefully. Treatment for the patients was given immediately without considering the gestational age. Conclusion: No harmful effect was observed for neonates even if the drugs were given in the first trimester of pregnancy. [Indones J Obstet Gynecol 2009;33-4:210-5] Keywords: profile, pregnancy, tuberculosis
AntiMüllerian Hormone Level in Laparoscopic Cystectomy Budipramana, Edwin; Abdullah, Nusratuddin; Tessy, Telly
Indonesian Journal of Obstetrics and Gynecology Volume 4, No. 4, October 2016
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (93.084 KB) | DOI: 10.32771/inajog.v4i4.449

Abstract

Objective: To evaluate the impact of laparoscopic cystectomy using cautery and suturing technique on the ovarian reserve represented by the level of Anti-Müllerian Hormone (AMH) serum. Method: This used prospective cohort study design conducted in Dr. Wahidin Sudirohusodo Hospital, Department of Obstetrics and Gynecology, Faculty of Medicine Universitas Hasanuddin, Makassar, from November 2014 to October 2015. We got total samples of 60 subjects divided into cautery and suturing group. Anti-Mullerian hormone serum test was examined on all subjects pre and post laparoscopic cystectomy. Result: The result indicated a significant decrease of AMH level undergoing laparoscopic cystectomy both cautery and suturing technique; whereas, more dominant results were showed in the cautery group (p0.05). Conclusion: The decline in the number of ovarian reserve as described by the reduction of AMH level occurs significantly in both cauterization and suturing technique, which are more dominant reduction in the cauterization group. [Indones J Obstet Gynecol 2016; 4-4: 203-207] Keywords: Anti-Müllerian Hormone, laparoscopic cystectomy, ovarian reserve
Kualitas Kehidupan Seksual Penderita Endometriosis Sebelum dan Sesudah Laparoskopi Operatif HADISAPUTRA, W.
Indonesian Journal of Obstetrics and Gynecology Volume. 30, No. 4, October 2006
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Tujuan: Untuk mengevaluasi kualitas hubungan seksual penderita endometriosis sebelum dan setelah menjalani intervensi Laparoskopi operatif. Rancangan/rumusan data: Studi deskriptif analitik. Bahan dan cara kerja: Penelitian deskriptif analitik pada kasus kasus infertilitas dengan sangkaan endometriosis yang menjalani laparoskopi operatif dari tanggal 1 Juni 2004 s.d Juli 2005, di Klinik Raden Saleh Departemen Obstetri dan Ginekologi FKUI/RSCM. Pengisian kuesioner dilakukan sebelum tindakan dan satu tahun pasca tindakan. Pengolahan statistik dilakukan dengan uji kemaknaan Chi square dan uji Fisher. Hasil: Dari 40 subjek penelitian didapat perbaikan pada intensitas orgamus secara sangat bermakna (p = 0,0009) dan hilangnya dispareuni secara bermakna (p = 0,0026), perbaikan dalam rasa puas (p = 0,0396). Serta perasaan lebih rileks (p = 0,045). Sedangkan beberapa keadaan yang tidak berbeda bermakna yaitu dalam hal variasi aktivitas seksual, lama aktivitas seksual serta frekwensi hubungan seks perminggu. Kesimpulan: Intervensi Laparoskopi operatif pada penderita endometriosis khususnya tindakan koagulasi ligamentum sakrouterina menyebabkan perbaikan kualitas kehidupan seksual secara bermakna. [Maj Obstet Ginekol Indones 2006; 30-4: 219-22] Kata kunci: endometriosis, ligamentum sakrouterina, dispareuni, orgasmus, kolsu
Homocysteine Level in the Blood and Follicular Fluid is Higher in Infertile Women with Endometriosis Natadisastra, Muharam
Indonesian Journal of Obstetrics and Gynecology Volume. 37, No. 2, April 2013
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To compare and determine the differences in the level of homocysteine in the blood and follicular fluid in infertile women with and without endometriosis, then analyze the effect of homocysteine levels to oocyte quality. Methods: This study was cross-sectional study. Fifty-nine subjects following the in-vitro fertilization program are included in the admission criteria were divided into two equal groups, ie groups of endometriosis and without endometriosis consecutively (consecutive sampling). Each subject taken from the blood and follicular fluid then measured the levels of homocystein levels with immuoassay method. The mean of each group was statistically tested with an independent t test. Result: The mean levels of homocysteine in the blood is higher in the endometriosis group than without endometriosis group and it was statistically significance (8.34 ± 2.68 vs 6.71 ± 1.56, p=0.007; 95% CI: 0.02417-0.14657). Similarly, the levels of homocysteine in follicular fluid , the endometriosis group is higher and statistically significance (6.19 ± 1.67 vs 3.46 ± 1.03; p= 0.000; 95% CI: 0.19310-0.32353). All oocytes are in good quality in both groups, maturation grade 3. There is a correlation between the levels of homocysteine in the blood and follicular fluid in the endometriosis group and assessed with Pearson test, and it found significant (p = 0.002) and the correlation value 0.553 (moderate correlation strength) and direction of a positive correlation. Conclusion: The mean levels of homocysteine in the blood and follicular fluid in infertile women with endometriosis is higher than without endometriosis and were statistically significantly different. These homocysteine levels does not affect the quality of oocytes. There is a positive correlation between the levels of homocysteine in the blood and follicular fluid in endometriosis group. [Indones J Obstet Gynecol 2013; 37-2: 92-8] Keywords: endometriosis, homocysteine, infertility, oocyte quality
Vaksin Human Papillomavirus: Suatu Alternatif dalam Pengendalian Kanker Serviks di Masa Depan Aziz, M.F.
Indonesian Journal of Obstetrics and Gynecology Volume. 30, No. 1, January 2006
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Kanker serviks merupakan kanker yang terbanyak ditemukan di Indonesia. Human Papiloma Virus merupakan penyebab kanker ini. Di Indonesia program deteksi dini dengan tes Pap sulit dilaksanakan karena keterbatasan dana, tenaga dan fasilitas. Imunisasi dengan vaksin Human Papiloma Virus diharapkan dapat merupakan Prevalens atau Insidens kanker serviks secara drastis. Meskipun masih dalam percobaan namun hasilnya cukup menggembirakan baik sebagai pencegahan infeksi HPV maupun pengobatan terutama pada lesi prakanker.
Clinical appearance and vaginal cytology of atrophic vaginitis in postmenopausal women Immanuel, Agnes Imelda
Indonesian Journal of Obstetrics and Gynecology Volume. 34. No. 2, April 2010
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To find out atrophic vaginitis pattern in postmenopausal women based on clinical appearance and vaginal cytology. Method: Descriptive retrospective study with hypothesis cohort to find out clinical appearance and vaginal cytology of atrophic vaginitis based on distribution of estrogen effect (maturation value/ total maturation index) in post menopausal women in outpatient clinic of tertiary hospital in Manado, North Sulawesi. Result: There were 50 subjects met the inclusion criteria. Most of them are 55 to 59 years old, with length of menopausal period 6 to 20 years, and onset of menopause in 45 to 49 years old. Cytology study showed that atrophic vaginitis present in 66% patients. Clinical symptoms are ranging from vaginal dryness (10%), vaginal discharge (6%), and dyspareunia (20%). From clinical appearance we found 44% women had atrophic vaginitis based on vaginal secretion, 42% based on macroscopic surface/integrity of vaginal epithelium, 54% based on vaginal rugae and elasticity, and 42% based on vaginal color. However, 80% of all participants showed vaginal pH more than 7 and most of them categorized as having atrophic vaginitis. Conclusion: By using clinical appearance, we found 42% to 54% of menopausal women had atrophic vaginitis, while cytology study confirmed 66% having it. [Indones J Obstet Gynecol 2010; 34-2: 92-6] Keywords: clinical appearance, cytology, menopause, atrophic vaginitis

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