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INDONESIA
Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia)
Published by Perkumpulan Obstetri dan Ginekologi Indonesia
ISSN : 23386401     EISSN : 23387335     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
The Indonesian Journal of Obstetrics and Gynecology is an official publication of the Indonesian Society of Obstetrics and Gynekology. INAJOG is published quarterly.
Arjuna Subject : -
Articles 1,731 Documents
 1   2   3   4   5 
Distention Media in Hysteroscopy for Diagnostic and Operative Procedure Hadisaputra, Wachyu
Indonesian Journal of Obstetrics and Gynecology Volume. 34, No. 3, July 2010
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (35.434 KB)

Abstract

Objective: Hysteroscopy is the "gold-standard" procedure used to describe the morphology of uterine cavity and the presence of intrauterine lesions and it is a minimally invasive intervention that can be used to diagnose and treat many intrauterine and endocervical problems. Hysteroscopy requires uterine distention for the effective visualization of the uterine cavity and the clearing of blood and tissue debris. Options for uterine distention include insufflation with carbon dioxide (CO2) gas, and instillation with electrolytic and nonelectrolytic liquid distention media. In this review, we would like to review known available distending media and its characteristics for diagnostic and operative hysteroscopy. Method: Literature review. Conclusion: Carbon dioxide and normal saline are the most preferable distention media for diagnostic hysteroscopy. There is no significant difference between these medium in terms of visualization quality, but most practitioners prefer to use normal saline because of it’s availability and acceptability, quick performance, fewer additional procedures, more satisfaction rate, and good visualization. Low viscosity fluids are the most preferable media for operative hysteroscopy. Low viscous-electrolytic fluids, mostly normal saline is recommended in operative cases using mechanical, laser or bipolar energy that requires no electricity. Nonelectrolytic low-viscosity fluids are most preferable for extensive operative procedures using electrosurgery. Mannitol are chosen over glycine or sorbitol when using monopolar electrosurgery. [Indones J Obstet Gynecol 2010; 34-3: 150-4] Keywords: hysteroscopy, distention media, diagnostic procedure, operative procedure
Eliminasi Human Papillomavirus (HPV) dan Respons Terapi pada Adenokarsinoma Serviks dan Karsinoma Sel Skuamos Serviks yang mendapat pengobatan Kemoradiasi TJOKROPRAWIRO, B. A.; HARTONO, P.; ANDRIJONO, ANDRIJONO; BUDIONO, BUDIONO; SUPRIANA, N.
Indonesian Journal of Obstetrics and Gynecology Volume. 32, No. 2, April 2008
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (68.356 KB)

Abstract

Tujuan: Tujuan penelitian ini adalah untuk mengetahui eliminasi DNA HPV risiko tinggi pada karsinoma sel skuamous serviks (KSS) dan adenokarsinoma serviks yang mendapat pengobatan kemoradiasi dan kaitannya dengan respons pengobatan. Bahan dan cara kerja: 22 penderita kanker serviks dengan jenis histopatologi adenokarsinoma dan 26 penderita kanker serviks dengan jenis histopatoloi KSS yang terdiri dari stadium IB-IIIB (FIGO) diambil sebagai sampel secara konsekutif dari penderita yang berkunjung dan dirawat di poliklinik dan ruangan onkologi ginekologi Rumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo Jakarta antara Juli 2005 dan Juli 2006. Pemeriksaan DNA HPV risiko tinggi dengan metode Hybrid Capture 2 (HC2) pada semua sampel tersebut menunjukkan hasil yang positif. Semua penderita mendapat pengobatan kemoradiasi. Pascakemoradiasi dilakukan penilaian respons pengobatan secara klinik dan pemeriksaan HC2 untuk melihat eliminasi DNA HPV risiko tinggi pada penderita tersebut. Hasil: Eliminasi DNA HPV risiko tinggi pada kanker serviks jenis adenokarsinoma lebih kecil dibanding dengan kanker serviks jenis KSS. Pascapemberian kemoradiasi, pada adenokarsinoma terjadi eliminasi DNA HPV 59,1% penderita dibanding dengan kelompok KSS di mana terjadi eliminasi DNA HPV risiko tinggi pada 76,9% penderita. Jenis Adenokarsinoma juga mempunyai angka persistensi DNA HPV risiko tinggi yang lebih besar (40,9%) dibanding dengan jenis KSS (23,1%). Penelitian ini menunjukkan respons pengobatan terhadap kemoradiasi antara kanker serviks dengan jenis adenokarsinoma dan KSS tidak berbeda dan hasil analisis menunjukkan bahwa antara respons terapi dan eliminasi DNA HPV risiko tinggi tidak terdapat hubungan. Pemeriksaan HC2 pascakemoradiasi masih bisa positif pada tumor dengan respons komplit. Kesimpulan: Persistensi DNA HPV risiko tinggi pascakemoradiasi lebih banyak terjadi pada kanker serviks jenis adenokarsinoma dibanding dengan jenis KSS. Untuk melihat apakah hal ini berkaitan dengan terjadinya rekurensi maka diperlukan penelitian dengan waktu pengamatan yang lebih lama. [Maj Obstet Ginekol Indones 2008; 32-2: 105-15] Kata kunci: kanker serviks, HPV, kemoradiasi
Profile of Estrogen Metabolism in Endometriosis Patients Verani, Tirsa; Sumapradja,  Kanadi
Indonesian Journal of Obstetrics and Gynecology Volume. 2, No. 3, July 2014
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (115.019 KB) | DOI: 10.32771/inajog.v2i3.394

Abstract

Objective: To assess the estrone (E1), estradiol (E2) and estriol (E3) blood level and its ratio (E2:E1, E2:E3 and E1:E3) between women with and without endometriosis. Method: We performed an analytical cross sectional study with 27 women with endometriosis and 27 women without endometriosis who met the inclusion criteria. The samples were recruited in Dr. Cipto Mangunkusumo hospital and other satellite hospitals from October 2012 to April 2013. The blood level of estrogen metabolites was examined by enzyme-linked immunosorbent assay (ELISA). Comparison between the two groups was analyzed by using Mann- Whitney test. Result: The level of estrone was found to be lower in endometriosis group compared to that in the control group (54.66 pg/ml vs 73.52 pg/ml, p=0.229). Similarly, the levels of estradiol and estriol were lower in endometriosis group (29 pg/ml vs 35 pg/ml, p=0.815 and 1.11 pg/ml vs 1.67 pg/ml, p=0.095, consecutively). The E2:E1 ratio was higher in endometriosis group (0.51 pg/ml vs 0.38 pg/ml, p=0.164), as well as E2:E3 ratio (26.53 pg/ml vs 21.11 pg/ml, p=0.223) and the E1:E3 ratio (58.55 pg/ml vs 50.28 pg/ml, p=0.684). However, all those differences were not statistically significant. Conclusion: The estrone, estradiol and estriol levels in women with endometriosis were lower compared to those in women without endometriosis. The ratio of E2:E1, E2:E3 and E1:E3 were higher in endometriosis group. However, all those differences failed to reach statistical significance. [Indones J Obstet Gynecol 2014; 3: 127-131] Keywords: endometriosis, estradiol, estriol, estrogen, estrone
Promising Male Hormonal Contraceptive are Well Established Soon a Reality Gunardi, Eka R; Soetarso, Arnold; Addina, Putri
Indonesian Journal of Obstetrics and Gynecology Volume. 3, No. 4, October 2015
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (144.842 KB) | DOI: 10.32771/inajog.v3i4.60

Abstract

Objective: To understand the modalities used for male hormonal contraception. Methods: Literature review Conclusion: Male contraceptive methods are still limited but hormonal contraceptive methods are being developed. The basic mechanism of male hormonal contraception is to inhibit spermatogenesis by suppression of the hypothalamic-pituitary-testicular axis function. Administration of testosterone or androgen derivative that is given in combination with progestin or GnRH antagonist shows that male hormonal contraceptive is reversible, effective, and acceptable as a male contraceptive method. However, no method of male hormonal contraceptive is ready for clinical use and marketed due to limited studies. [Indones J Obstet Gynecol 2015; 3-4: 239-243] Keywords: GnRH antagonist, male hormonal contraceptive, progestin, testosterone
The Association between Menstrual Disorder and Work Disturbance among Employees Nuranna, Laila; Abdullah, Iftikar; Kayika, I. Putu G.; Pratama, Gita
Indonesian Journal of Obstetrics and Gynecology Volume 6. No. 1. January 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (2269.202 KB) | DOI: 10.32771/inajog.v6i1.751

Abstract

Objective: To investigate the association between menstrualdisorders including each menstrual cycle disorder, durationand volume of menstrual bleeding disorder, menstrual intervaldisorder, and another disorder that related to menstruationagainst disruption of work among employees.Methods: This study used a cross sectional design. Samplerandomization with winpepi® software for Windows 7®. Dataanalysis using SPSS 24® software for Windows 7®.Results: A total of 150 subjects were recruited in this study. Theprevalence of menstrual disorder was 87%, menstrual cycledisorder 3%. Menstrual volume disorder 31%, 15% menstrualabnormalities, 83% menstrual pain disorder and premenstrualsyndrome 71%. Prevalence of work disturbance was 49% formild disturbance, 47% for moderate disturbance and severework disturbance by 4%. There was a relationship betweenmenstrual volume disorder, hypermenorrhoea, and menstrual /dysmenorrhoea pain to occupational disruption among theemployee at RSCM (p <0.001). The submission of the proposedleaves due to menstrual disorder in the proposed permit for1 day by 73%.Conclusion: The prevalence of severe work disturbance due tomenstruation is not high but can lead to disruption in runningjobs and activities. However, it is important to be a concern so thatthe employees get good management and care.Keywords: employee, menstrual leave, menstrual disorder, prevalence,work disturbance
Prevalence of Sexual Dysfunction Based on Female Sexual Function Index and Perception of Newly Bride in Jati Village and Its Related Factors Suryadi, Angga J.
Indonesian Journal of Obstetrics and Gynecology Volume. 34, No. 4, October 2010
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (31.027 KB)

Abstract

Objective: To found prevalence of female sexual dysfunction based on FSFI and perception of newly bride in Jati Village and its related factors. Method: A cross-sectional study was conducted in 33 newlybrides in Jati Village, East Jakarta, who got married for the first time within less than 6 months and did not have severe disease. We translated and validated the Female Sexual Function Index (FSFI) and added items on sexual dysfunction perception. The questionnaires were self-administered by the respondents. Results: Almost half (42.4%) of the participants were 26 - 30 years old. The most frequent sexual dysfunction domains were sexual arousal disorder and sexual pain. Frequency of sexual intercourse was significantly associated with sexual dysfunction based on FSFI. Marital age and frequency of sexual intercourse were significantly associated with sexual dysfunction based on participants’ perception. Agreement between FSFI score and sexual dysfunction perception was substantial (Kappa = 0.615, p < 0.001). Conclusion: The sexual dysfunction prevalence based on FSFI was 15.2% and based on perception was 12.1%. Participants age and frequency of sexual intercourse had a significant relationship with sexual dysfunction. Most of participants who felt that they had sexual dysfunction did not seek for medical services. [Indones J Obstet Gynecol 2010; 34-4: 170-4] Keywords: FSFI, newly bride, prevalence, sexual dysfunction
Perbandingan kadar regulatory T-cells antara kehamilan normal dan abortus (cetak ralat) SUHEIMI, I.
Indonesian Journal of Obstetrics and Gynecology Volume. 33, No. 2, April 2009
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (134.913 KB)

Abstract

Tujuan: Untuk mengetahui peran Treg dalam kelangsungan kehamilan dengan mengukur kadar Treg dalam kehamilan normal di bawah 20 minggu, mengukur kadar Treg dalam kejadian abortus dan membandingkan kadar Treg dalam kehamilan normal di bawah 20 minggu dan dalam kejadian abortus. Tempat: RSUPN Dr. Cipto Mangunkusumo, baik di IGD lantai 3 maupun poliklinik Obstetri dan Ginekologi. Bahan dan cara kerja: Penelitian bersifat penelitian observasional tanpa intervensi berupa studi comparative cross-sectional, dilakukan pada kelompok perempuan hamil normal dan kelompok perempuan yang mengalami abortus yang datang ke tempat penelitian. Pengumpulan data dilakukan sejak subjek penelitian datang di IGD lantai 3 atau poliklinik Obstetri dan Ginekologi RSCM. Jika kasus sesuai dengan kriteria penerimaan dan penolakan maka dilakukan informed consent untuk mendapat persetujuan penelitian. Diambil darah vena pasien sebanyak 50 mikroliter dan dimasukkan ke dalam alat flowcytometry dengan reagen spesifik untuk pemeriksaan CD45 (Per-CP- 347464), CD4 (SIPC-340133) dan CD25 (PE-341009) untuk kemudian dihitung jumlah Treg dengan sistem lyse no washed menggunakan software cellquest pro. Output dari alat flowcytometry tersebut kemudian dicatat. Pasien dengan kehamilan normal (kelompok kontrol) di follow-up sampai kehamilannya mencapai 20 minggu untuk memastikan tidak terjadinya abortus sampai batas waktu tersebut. Jika pasien dengan kehamilan normal pada saat pemeriksaan ternyata mengalami abortus di bawah 20 minggu, maka pasien tersebut akan dimasukkan ke dalam kelompok dengan kejadian abortus (kelompok kasus). Hasil: Pada uji statistik perbandingan rerata persentase sel CD45 didapatkan bahwa tidak terdapat perbedaan yang bermakna secara statistik antar kedua kelompok, di mana rerata kelompok kasus adalah 10,96 ± 6,57% sel dibandingkan dengan rerata 9,60 ± 5,30% sel pada kelompok kontrol dengan p = 0,610. Pada perbandingan kadar Treg dari hasil uji statistik didapatkan Median pada kelompok kasus (2,45 sel/μl) dibandingkan dengan Median kelompok kontrol (2,53 sel/μl) tidak menunjukkan perbedaan yang bermakna secara statistik dengan p = 0,946 (uji korelasi Mann-Whitney). Kesimpulan: Penelitian ini mendapatkan bahwa tidak terdapat hubungan antara kadar Regulatory T-cells (Treg) dengan kejadian abortus. [Maj Obstet Ginekol Indones 2009; 33-2: 93-100] Kata kunci: regulatory T-cells, Treg, abortus
Bladder Function after Hysterectomy Wijaya, Johanna; Tendean, Hermie; Laihad, Bismarck J
Indonesian Journal of Obstetrics and Gynecology Volume. 4, No. 2, April 2016
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (81.688 KB) | DOI: 10.32771/inajog.v4i2.83

Abstract

Objective: To determine the effect of hysterectomy on bladder function pre- and post-radical hysterectomy in early stage of cervical cancer. Method: This study was a pre-post intervention study. Data were collected through questionnaires from women who had radical hysterectomy and total hysterectomy in Prof. Dr. R. D. Kandou Manado general hospital and other networking hospitals since January 1st, 2014 to November 31st, 2014. We analyzed the data using Wilcoxon and Mann-Whitney statistical test. Result: There were each 18 respondents for the radical and total hysterectomy group in Prof. Dr. R. D. Kandou general hospital and networking hospitals. The age distribution of radical hysterectomy was 41-45 years old for 44.4%. The parity was dominated by second parity for 38.8%. In pre- and post-surgery, there were significant differences for urinary incontinence disorder (p=0.003), emptying disorder (p=0.008), urinary pain (p=0.034), and total urinary disorder (p=0.001). While, between radical and total hysterectomy, there was no significant difference in bladder function (p>0.05). Conclusion: There is an association before and after surgery to urinary function. However, there is no association between the radical and total hysterectomy group. [Indones J Obstet Gynecol 2016; 4-2: 97-100] Keywords: bladder function, cervical cancer, radical hysterectomy
Fetal Biometry is a Prerequisite Part of Modern Antenatal Care Salim, Azen
Indonesian Journal of Obstetrics and Gynecology Volume 6 No. 3 July 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (61.272 KB) | DOI: 10.32771/inajog.v6i3.776

Abstract

N/A
Lamellar Body Count has Higher Sensitivity and Specificity in the Prediction of Neonatal Respiratory Distress Syndrome Pradana, Aryando
Indonesian Journal of Obstetrics and Gynecology Volume. 36, No. 4, October 2012
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (97.778 KB)

Abstract

Objective: The study was designed to acquire the cut-off value for lamellar body count and its role in predicting the presence of Respiratory Distress Syndrome (RDS) in pregnancy with gestational age above 28 weeks. Method: Amniotic fluid specimens were collected by amniotomy during cesarean section from women with gestational age above 28 weeks. A haematology analyzer (Advia 120) was used to determine the lamellar body counts. We also performed foam stability test and observed the development of respiratory distress syndrome. Receiver operating characteristics curve was estimated to assess the threshold of lamellar bodies count that may predict the presence of Respiratory Distress Syndrome. Result: Fifty nine specimens were collected from woman with 29 - 42 weeks gestational age. The incidence of Respiratory Distress Syndrome was 15.3%. Area under the curve for lamellar body count was 0.94. Lamellar body count, with the best cut-off point of 50,000 cell/μl had sensitivity 89% and specifity 92% for predicting the presence of RDS, while the sensitivity of foam stability test was 67% and specificity was 90%. The negative predictive value of the lamellar body count was 98% slightly better than the negative predictive value of the foam stability test 94 %. Conclusion: Although both test are good predictor of RDS, lamellar body count has higher sensitivity and specificity. It also has more advantages as it only requires small amount of sample, fast, easy and more objective. [Indones J Obstet Gynecol 2012; 36-4: 176-80] Keywords: foam stability test, lamellar body, respiratory distress syndrome

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