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INDONESIA
Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia)
Published by Perkumpulan Obstetri dan Ginekologi Indonesia
ISSN : 23386401     EISSN : 23387335     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
The Indonesian Journal of Obstetrics and Gynecology is an official publication of the Indonesian Society of Obstetrics and Gynekology. INAJOG is published quarterly.
Arjuna Subject : -
Articles 1,760 Documents
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Primipara Undergoing Episiotomy had Lower Postpartum Sexual Function Lukas, Efendi
Indonesian Journal of Obstetrics and Gynecology Volume. 2, No. 2, April 2014
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (114.864 KB)

Abstract

Objective: To compare postpartum sexual functions between primipara with episiotomy and without episiotomy. Method: The research was conducted in public service section of Dr. Wahidin Sudiro Husodo hospital and a number of educational hospitals obstetrics and gynecology of Faculty of Medicine of Hasanuddin University, started from February to May 2012. The research evaluated the sexual function of postpartum with episiotomy in 171 primipara, and 150 primipara postpartum without episiotomy. Sexual function was measured by Female Sexual Function Index (FSFI) questionnaire which had been validated in various countries. The research was conducted with cross sectional approach. Samples were withdrawn with consecutive sampling method. The data was processed with SPSS version 17, with chi-square test, and significant level of 0.05. Result: Indicated that either the episiotomy or non-episiotomy group has undisturbed sexual function score (>28.5), however, higher score was indicated in non- episiotomy group (65.477) compared to the episiotomy group (59.70), (p0.05). [Indones J Obstet Gynecol 2014; 2: 91-95] Keywords: episiotomy, FSFI, primipara, sexual functions
PPARy Expression in Eutopic and Ectopic Endometrium of Reproductive Age Women with Endometriosis Dilmy, Adya F; Natadisastra, Muharam; Sumapradja, Kanadi
Indonesian Journal of Obstetrics and Gynecology Volume. 3, No. 4, October 2015
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (173.729 KB) | DOI: 10.32771/inajog.v3i4.55

Abstract

Objective: To evaluate the expression of PPARy receptor and to compare its expression in eutopic and ectopic endometrium in women with endometriosis. Method: This is a cross sectional study. Ten female subjects with endometriosis that underwent laparoscopy or laparotomy who fulfilled the inclusion criteria were recruited by consecutive sampling. Two samples were taken, eutopic endometrium and ectopic endometrium from endometriosis cyst wall during surgery of each subject. PPARy expression was examined by two-step RT-qPCR. Our data was statistically examined using the paired t-test and Pearson’s correlation test. Result: PPARy was found to be expressed in eutopic and ectopic endometrium of women with endometriosis using the RT-qPCR method. The expression of PPARy was not statistically different in eutopic and ectopic endometrium (1.16 relative fold vs 1.25 relative fold; p=0.26). By Pearson’s correlation there was a weak positive correlation between PPARy expression of eutopic and ectopic endometrium (r=0.16). Conclusion: PPARy was detected by two-step RT-qPCR in eutopic and ectopic endometrium of women with endometriosis. Semiquantification of PPARy expression showed that there was no significant difference between PPARy expression in eutopic and ectopic endometrium of women with endometriosis. There was a weak positive correlation between PPARy expression in eutopic and ectopic endometrium of women with endometriosis. [Indones J Obstet Gynecol 2015; 3-4: 200-205] Keywords: endometriosis, PPARy, two-step RT-qPCR
The Accuration of LiquidBased Cytology and HPV DNA Test Combination as Precervical Cancer Lesion Screening Indarti, Junita; Pratama, Yuven S
Indonesian Journal of Obstetrics and Gynecology Volume. 5, No. 4, October 2017
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (91.721 KB) | DOI: 10.32771/inajog.v5i4.570

Abstract

Objective: To investigate the accuracy of liquid-based cytology, HPV DNA test, and the combination of liquid-based cytologyband HPV DNA test, compared to histopathology as the gold standard of precervical cancer lesion screening. Methods: This was a cross-sectional study. The medical records of patients who came to the Women’s Health Clinic of Dr. Cipto Mangunkusumo Hospital during the period of July 2013 to December 2015 were evaluated. Results: The high risk type HPV DNA is detected in 76% CIN 1, 88.46% CIN 2, and 84.21 CIN 3 in histopathology results. The accuracy of liquid-based cytology; sensitivity 88.54%, specificity35.71%, PPV 75.89%, and NPV 57.69%. The accuracy of HPV DNA; sensitivity 81.25%, specificity 78.57%, PPV 89.66%, and NPV 64.71%. The accuracy of combination: sensitivity 94.79%, specificity 35.71%, PPV 77.12%, and NPV 75%. Conclusion: The addition of HPV DNA test increased the sensitivity from 88.54% to 94.79% because of decreasing of false negative of liquid-based cytology. This thing has showed that the combination of liquid-based cytology and HPV DNA test could the one of the option of precervical cancer lesion screening method, especially in secondary or tertier health center in Indonesia. Keywords: accuracy test, HPV DNA, liquid-based cytology, precervical cancer lesion, precervical cancer lesion screening
Factors Influencing Maternal Mortality from Severe Preeclampsia and Eclampsia Khusen, Denny
Indonesian Journal of Obstetrics and Gynecology Volume. 36, No. 2, April 2012
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To analyze risk factor, both clinical and laboratory findings, associated with maternal mortality from severe preeclampsia and eclampsia in Atma Jaya Hospital. Methods: This was a retrospective case control study. All medical records of maternal death associated with severe preeclampsia and eclampsia between 1st January 2009 and 31st December 2011 were obtained and then information about risk factors were collected and tabulated. Risk factor analyzed were maternal age, gestational age, parity, coexisting medical illness (hypertension), antenatal examination status, maternal complications, systolic and diastolic blood pressure at admission, and admission laboratory data. Results: There were 19 maternal deaths associated with severe preeclampsia and eclampsia during period of study (Consisted of 6 cases of eclampsia and 13 cases of severe preeclampsia). Maternal mortality rate for severe preeclampsia and eclampsia were 16.7% and 33.3% respectively. Multivariate analysis identified the following risk factors associated with maternal death: gestation age
Bcl-2 dan Indeks Apoptosis pada Hiperplasia Endometrium non-atipik simpleks dan kompleks CAHYANTI, R.D.
Indonesian Journal of Obstetrics and Gynecology Volume. 33, No. 1, January 2009
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (170.456 KB)

Abstract

Tujuan: Untuk menilai perbedaan dan hubungan ekspresi Bcl-2 dan indeks apoptosis pada hiperplasia endometrium non-atipik simpleks dan kompleks. Bahan dan cara kerja: Blok parafin jaringan hiperplasia endometrium non-atipik dari hasil kuretase bertingkat sebanyak masingmasing 28 kasus hiperplasia simpleks dan kompleks. Ekspresi protein Bcl-2 dinilai dengan pengecatan imunohistokimia dan ditentukan persentase immuno-staining Bcl-2 pada kelenjar endometrium serta intensitas staining. Penilaian apoptosis pada potongan jaringan yang sama dengan menggunakan metode terminal deoxynucleotidyl transferasemediated deoxy-uridine triphosphate nick end labeling (TUNEL) assay. Persentase jumlah positif sel dan sel yang mengalami apoptosis dihitung dalam 10 lapangan pandang (dengan pembesaran 40 x). Analisis data untuk uji beda 2 kelompok tidak berpasangan dan korelasi dengan derajat kemaknaan p ≤ 0,05 serta dilakukan perhitungan rasio prevalensi. Hasil: Karakteristik subjek pada kedua kelompok sama. Tidak terdapat perbedaan intensitas staining positif kuat pada epitel kelenjar hiperplasia simpleks 85,7% pada hiperplasia kompleks 96,4% (p = 0,176). Ekspresi Bcl-2 pada hiperplasia endometrium kompleks lebih tinggi dibandingkan yang simpleks (p = 0,013). Nilai ekspresi Bcl-2 dengan cut off point 0,92 didapatkan bahwa endometrium dengan Bcl-2 ≥ 0,92 mempunyai risiko 2,6 kali untuk terjadinya hiperplasia non-atipik kompleks (p = 0,001; Rasio Prevalensi 2,6; 95%, CI = 1,3 - 5,1). Indeks apoptosis pada hiperplasia endometrium simpleks lebih tinggi dibandingkan yang kompleks (p = 0,014). Nilai indeks apoptosis dengan cut off point 9 menunjukkan bahwa pada endometrium dengan indeks apoptosis ≥ 9 mempunyai risiko 3,8 kali terjadinya hiperplasia non-atipik simpleks (p = 0,002; Rasio Prevalensi 3,8; 95%, CI = 1,4 - 9,9). Pada hiperplasia yang simpleks terdapat korelasi negatif derajat sedang antara ekspresi Bcl-2 dan indeks apoptosisnya (r = -0,664; p = 0,000), sedangkan pada yang kompleks tidak adanya suatu korelasi negatif (r = -0,208; p = 0,85). Kesimpulan: Ekspresi Bcl-2 pada hiperplasia endometrium nonatipik kompleks lebih tinggi dibanding yang simpleks dan nilai indeks apoptosis lebih rendah pada hiperplasia kompleks dibandingkan yang simpleks. Korelasi negatif antara ekspresi Bcl-2 dan indeks apoptosis hanya didapatkan pada kasus hiperplasia non-atipik simpleks. [Maj Obstet Ginekol Indones 2009; 33-1: 48-55] Kata kunci: Bcl-2, indeks apoptosis, hiperplasia endometrium nonatipik simpleks dan kompleks
Impact of Uterine Prolapse Surgery on Improvement of Bowel Symptoms Fauzi, Amir
Indonesian Journal of Obstetrics and Gynecology Volume. 2, No. 3, July 2014
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To find the effectiveness of uterine prolapse surgery in patients with bowel symptoms. Method: Clinical trial without comparison study of 32 consecutive women who underwent surgery for grade III and IV uterine prolapse with bowel symptoms. Bowel symptoms score was evaluated before and three months after surgery by using the Australian Pelvic Floor Questionnaire. Data was analyzed using SPSS version 20. Result: There were significant mean differences between bowel symptoms score three months after surgery for grade III and IV uterine prolapse and before surgery although there were patients with persistent symptoms. Bowel symptoms scores include constipation, flatus incontinence, fecal incontinence, fecal urgency, defecation frequency, defecation consistency, incomplete bowel emptying, laxative use, and frequency of defecation disorder score, with p
Severe Complication of Uterine Perforation and Ileum Prolapse after Having Unsafe Abortion Pradana, Aryando
Indonesian Journal of Obstetrics and Gynecology Volume. 36, No. 3, July 2012
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: Discuss complication after unsafe abortion and management of uterine perforation after curettage. Methods: Case report. Conclusion: Uterine perforation and ileum prolapse in this patient was a complication from unsafe abortion from unregistered health practicioner, fortunately the outcome is good, although actually it could be prevent. [Indones J Obstet Gynecol 2012; 36-3:150-3] Keywords: hysteroraphy, ileum anastomose, ileum laceration, ileum prolapse, ileum resection, incomplete abortion, uterine perforation
Cytology of uterine cervix after one year use of Depo Provera and Cyclofem Kambu, Jan Pieter
Indonesian Journal of Obstetrics and Gynecology Volume. 33. No. 4, October 2009
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: The objective was to examine cervical cytology findings from conventional Pap smear examination in Depo-Provera® and Cyclofem® acceptor in one-year period. Method: The study design is descriptive observational involving 35 Depo-Provera® and 35 Cyclofem® acceptor. We follow up their cytology findings prospectively. This study was conduct in FER and gynecology clinics at Dr. Kariadi Hospital Semarang also at Halmahera and Ngesrep public health service. The subjects were women, aged 20 - 40 years old who chosen Depo-Provera® and Cyclofem® as their contraceptive methods. This study began on December 2006, all subjects who met inclusion criteria underwent initial cytology screening. On December 2007, and there were 70 subjects. They underwent cytology examination at month sixth (simultaneously with third Depo-Provera® injection and seventh Cyclofem® injection) and at month twelve (simultaneously with fifth Depo-Provera® injection and thirteenth Cyclofem® injection). Distribution frequency was analyzed using univariate analysis and data shown as mean and standard deviation whereas bivariate analysis was conduct with X2 and t-test. Cytology examination was conduct in anatomy pathology laboratory at Medicine Faculty, Diponegoro University/Dr. Kariadi Hospital, Semarang. Result: Inflammation rates tend to increase on Depo-Provera® group compare to Cyclofem® group. At first cytology result there is no difference between two groups, it suggest that both groups had same baseline characteristic. Thereafter, at second and third examination, Depo-Provera® group significantly showed higher inflammation and dysplasia rates compare to Cyclofem® group. Conclusion: After one-year period, there was difference on cervical cytology results that is inflammation rates which higher on Depo- Provera® acceptor compare to Cyclofem®. [Indones J Obstet Gynecol 2009; 33-4: 233-8] Keywords: pap smear, Depo-Provera®, Cyclofem®, Pap smear on hormonal contraception
A Simple Ultrasound Examination as Diagnostic Tool for Malignant Ovarian Tumor Wigin, Christin; Andrijono, Andrijono
Indonesian Journal of Obstetrics and Gynecology Volume 4, No. 4, October 2016
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (98.519 KB) | DOI: 10.32771/inajog.v4i4.452

Abstract

Objective: To know the diagnostic value of simple ultrasound examination to detect malignant ovarian tumor. Method: This study used cross-sectional design in gynecology outpatientclinic at Dr. Cipto Mangunkusumo Hospital. We recruited the patients with ovarian tumor undergoing surgery between March and July 2015. Samples were taken using consecutive sampling. Analysis was done using Chi-square test and logistic regression to find the relationship between ultrasound morphologic patterns with histopathologic findings, where the significant relationship was p value less than 0.05. Furthermore, a model derived from logistic regression was made to calculate the probability having ovarian malignancy. Result: There were 80 subjects which 58 subjects (72.5%) had benign tumor and 22 subjects (27.5%) had malignant tumor. Ultrasound examination result using  2 morphologic patterns gave malignant result in 53.8% subjects with the sensitivity of 100%, specificity of 82.8%, positive predictive value of 68.8%, and negative predictive value of 100%. The most important patterns were irregular internal cyst wall, multilocular, presence of papillary projection, and presence of solid component. The probability of subject having ovarian malignancy with  3 morphologic patterns was more than 88.9%. Conclusion: Simple ultrasound examination can be used to detect malignant ovarian tumor. [Indones J Obstet Gynecol 2016; 4-4: 222-226] Keywords: diagnostic, histopathology, morphology pattern; ovarian tumor; ultrasonography
Hubungan antara Derajat Perdarahan dan Ketebalan Endometrium dengan Kerapatan Reseptor Estrogen dan Progesteron pada Wanita Perimenopause dengan Perdarahan Uterus Disfungsi (PUD) NATAPRAWIRA, D. S.; ANWAR, R.; BIBEN, A.
Indonesian Journal of Obstetrics and Gynecology Volume. 30, No. 4, October 2006
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (329.703 KB)

Abstract

Tujuan: Mengetahui hubungan antara derajat perdarahan dan ketebalan endometrium dengan kerapatan reseptor estrogen (RE) dan progesteron (RP) pada kelenjar dan stroma endometrium wanita perimenopause dengan PUD. Metode: Penelitian observasional analitik dengan rancangan crosssectional dilakukan untuk mengetahui kerapatan RE dan RP dari jaringan kuretase dan hubungannya dengan derajat perdarahan dan ketebalan endometrium. Subjek penelitian adalah 30 wanita perimenopause berusia 40 - 51 tahun dan dilakukan pemeriksaan transvaginal ultrasound untuk mengukur ketebalan endometrium selanjutnya dilakukan pemeriksaan kerapatan RE dan RP dengan teknik histokimia. Analisis statistik untuk mengetahui hubungan ketebalan endometrium dengan kerapatan RE dan RP pada kelenjar dan stroma endometrium menggunakan uji Chi kuadrat. Untuk mencari hubungan antara ketebalan endometrium dan derajat perdarahan digunakan uji t. Kemaknaan ditentukan berdasarkan nilai p < 0,05. Hasil: Terdapat hubungan yang bermakna antara derajat perdarahan dengan ketebalan endometrium (p < 0,001). Tidak terdapat hubungan yang bermakna antara ketebalan endometrium dengan kerapatan RE baik pada kelenjar maupun stroma (p = 0,194; p = 0,748), juga pada hubungan antara ketebalan endometrium dengan kerapatan RP pada kelenjar endometrium (p = 0,375). Terdapat hubungan yang bermakna antara ketebalan endometrium dengan kerapatan RP di stroma endometrium yang makin rendah (p = 0,031). Tidak terdapat hubungan yang bermakna antara derajat perdarahan dengan kerapatan RE dan RP baik pada kelenjar (p = 0,189; p = 0,063) maupun stroma (p = 0,901; p = 0,071). Kesimpulan: Ketebalan endometrium mempengaruhi derajat perdarahan pada wanita perimenopause dengan PUD. Derajat perdarahan makin banyak pada endometrium yang makin tebal yang menunjukkan kerapatan RP yang sedikit. [Maj Obstet Ginekol Indones 2006; 30-4: 238-44] Kata kunci: derajat perdarahan, ketebalan endometrium, RE, RP, kelenjar endometrium, stroma endometrium, perimenopause, PUD

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