p-Index From 2021 - 2026
8.786
P-Index
This Author published in this journals
All Journal Jurnal Kependidikan: Penelitian Inovasi Pembelajaran Jurnal Penelitian Saintek Jurnal Ilmu Dasar Jurnal Matematika & Sains WIDYATAMA Biomedika Pharmacon Jurnal Penelitian Kesehatan Suara Forikes Journal of Community Services and Engagement Journal of Nutraceuticals and Herbal Medicine PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Kreativitas PKM Journal Health & Science : Gorontalo Journal Health and Science Community JURNAL FARMASIMED (JFM) Jurnal Penyuluhan Perikanan dan Kelautan Abdi: Jurnal Pengabdian dan Pemberdayaan Masyarakat INTEGRITAS : Jurnal Pengabdian Jurnal Ners Jurnal Layanan Masyarakat (Journal of Public Service) Yumary: Jurnal Pengabdian kepada Masyarakat IJECS: Indonesian Journal of Empowerment and Community Services Jurnal Farmasi dan Sains Indonesia (JFSI) Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Farmasi Sains dan Praktis Proceeding ISETH (International Summit on Science, Technology, and Humanity) Urecol Journal. Part C: Health Sciences Urecol Journal. Part D: Applied Sciences Prosiding University Research Colloquium Proceeding of International Conference Health, Science And Technology (ICOHETECH) Cakrawala: Jurnal Pengabdian Masyarakat Global Journal of Pharmaceutical and Sciences. Jurnal Ilmiah Kesehatan Jurnal Pengabdian Kesehatan Masyarakat Mulawarman CERATA Usadha Journal of Pharmacy Borneo Journal of Pharmacy Journal of Community Services and Engagement: Voice of Community (VOC) Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Kefarmasian Indonesia Journal of Nutraceuticals and Herbal Medicine Jurnal Sains dan Kesehatan Altifani Journal: International Journal of Community Engagement Journal of World Future Medicine, Health and Nursing
Claim Missing Document
Check
Articles

Senyawa-senyawa Oligomer Resveratrol dari Kulit Batang Shorea brunnescens (Dipterocarpaceae) Haryoto Haryoto; Yana Maolana Syah; Lia Dewi Juliawaty; Sjamsul Arifin Achmad; Jalifah Latip; Euis Holisotan Hakim
Jurnal Matematika & Sains Vol 11, No 3 (2006)
Publisher : Institut Teknologi Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Six resveratrol oligomers, namely (-)- ε-viniferin (1), (-)-laevifonol (2), (-)-vaticanol B (3), (-)-hemsleyanol D (4), (+)-isohopeaphenol (5), and (-)-hopeaphenol (6) have been isolated from the acetone extract of the stem bark of Shorea brunnescens. The structure determination of these compounds were based on spectroscopic data (UV, IR, 1H NMR), and compared with literature data. The cytotoxicity of isolated compounds against murine leukemia P-388 cells showed the IC50 values as 18.1, 23.2, 41.9, 12.3, 39.7, and 5.5 µM, respectively.
Pengelolaan Pembelajaran Lesson Study Mata Pelajaran Ipa Di SMA Negeri 1 Nogosari Kabupaten Boyolali Haryoto, Haryoto; Lestari, Marlupi Dwi; Suseno, Nugroho Adi
WIDYATAMA Vol 19, No 1 (2010)
Publisher : WIDYATAMA

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Pengelolaan Pembelajaran Lesson Study Mata Pelajaran Ipa Di SMA Negeri 1 Nogosari Kabupaten Boyolali Haryoto1), Marlupi Dwi Lestari2), Nugroho Adi Suseno3) 1)Staf Pengajar Progdi Magister Manajemen Pendidikan Program Pascasarjana Universitas Muhammadiyah Surakarta2)Guru Sekolah Menengah Atas Negeri 1 Nogosari, Kabupaten Boyolali3)Guru Sekolah Menengah Pertama Negeri 1, Kaliwungu, Kabupaten Semarang Abstract Quality of education in Nogosari High School still lower because there is use to function educational production approach which too centripetal at education input, less is paying attention of learning process, to increase quality of education conducted by real stages there are learning process of pass with lesson study approach. Learning process of lesson study is conducted represent learning process collaboration by teachers through three activities there are planning, implementation, and reflection. Planning is started identified the problem, analysis of problem, determination of problem priority to be solved, election the lesson model, making lesson plan, cozening method, physic appliance and assessment conducted together by collaboration. The implementation of lesson is conducted together, someone become teacher model and other is observation of learning process; observer may not bother of learning process, observer duty note important problem in lesson. The reflection is conducted after ending lesson, its analyzing learning process, teachers’ model submit what experienced by learning moment, while observer submit result of observation, then analyzed and looked for the way out of the problem of faced at the moment of lesson  implementation. Learning Process of lesson study in Nogosari High School implemented by collaboration between ‘science teacher’ and ‘study teacher’ which start planning until implementation, as for reflection is implemented every saturday of meeting learn or Team Working of Teacher. Result of learning for lesson study in Nogosari High School can improve the quality of education.  Keywords: Lesson Study
PENGEMBANGAN POTENSI EKSTRAK KULIT BUAH RAMBUTAN SEBAGAI BAHAN OBAT HERBAL ANTIHIPERKOLESTEROL Muhtadi, .; Haryoto, .; Sujono, Tanti Azizah; Indaryudha, Peni; Suhendi, Andi
Biomedika Vol 5, No 2 (2013): Biomedika Agustus 2013
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The rind of rambutan fruit (Nephelium lappaceum L.) has been reported to have a very strong antioxidant activity with IC50 value of 7.74 μg / mL. The fruit contains  avonoids and phenolic . This compounds are potentially as hypolipidemic effect. This study aims to determine the hypolipidemic effect of 96% of ethanolic extract of rind of rambutan fruit in wistar strain male rats. This research method is the pre- and post-control group design. 25 rats were divided into 5 groups. Group I (negative control) were treated by a solution of 0.5% CMC-Na, group II (positive control) were treatedby cholestyramine 0.8 kg / kg, whereas group III, IV and V treated by 96% of ethanolic extract of rind of rambutan with a dose of 125 , 250, and 500 mg / kg respectively. hiperkolesterlemia induction is done by giving a high cholesterol diet and feed for 4 weeks. High-cholesterol diet consists of cooking oil, quail egg yolk, water, PTU and feed high cholesterol consisting of margarine and standard feed. Treatment of mice was conducted for 2 weeks. The results showed that the 96% of ethanolic extract of rind of rambutan fruit with a dose of 125, 250, and 500 mg / kgbw have antihyperkolesterol activity 21.39 ± 6.61%, 31.15 ± 18.15%, and 60.75 ± 8, 26%.Keywords: Antihypercholestrol, Nephelium Lappaceum L., High-cholesterol diet
EFEK ANTIINFLAMASI EKSTRAK ETANOL KULIT KACANG TANAH (Arachis hypogaea L.) PADA TIKUS PUTIH JANTAN GALUR WISTAR YANG DIINDUKSI KARAGENIN Haryoto, Haryoto
Pharmacon Vol 11, No 1 (2010)
Publisher : Pharmacon

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (109.03 KB)

Abstract

Kulit kacang tanah mengandung luteolin yang berpotensi sebagai antiinflamasi secara in vitro dan in vivo. Penelitian ini bertujuan untuk mengetahui efek antiinflamasi ekstrak etanol kulit kacang tanah (Arachis hypogaea L.) pada tikus jantan galur Wistar yang diinduksi karagenin Penelitian menggunakan rancangan acak lengkap pola searah. Dua puluh lima ekor tikus putih jantan galur Wistar dibagi menjadi 5 kelompok. Kontrol negatif menggunakan CMC-Na 0,5% 2,5 mL/200 gBB, kontrol positif menggunakan Na-diklofenak 6,75 mg/kgBB. Ekstrak etanol kulit kacang tanah yang diujikan yaitu dosis 50, 100 dan 200 mg/kgBB. Larutan uji diberikan secara peroral dengan volume pemberian 2,5 mL/200 gBB 1 jam sebelum kaki hewan uji diradangkan dengan karagenin 1% secara subplantar. Pengukuran volume kaki tikus dilakukan tiap 0,5 jam selama 6 jam. Data volume udem dihitung nilai AUC (Area Under the Curve) rata-rata volume udem terhadap waktu dan persen daya antiinflamasi. Data dianalisis dengan anava satu jalan dan dilanjutkan uji LSD (Least Significant Difference) dengan taraf kepercayaan 95%.  Hasil penelitian menunjukkan bahwa ekstrak etanol etanol kulit kacang tanah (Arachis hypogae L.) dengan dosis 50, 100 dan 200 mg/kgBB mempunyai persen daya antiinflamasi berturut-turut sebesar 16,33%; 26,39% dan 31,70%, sedangkan Na-diklofenak 6,75 mg/kgBB sebesar 32,24%.Kata kunci: kulit kacang tanah (Arachis hypogaea L.), ekstrak etanol, antiinflamasi
Cytotoxicity of Methanol Leaf Extract of Artocarpus Altilis, Artocarpus Heterophyllus, and Artocarpus Camansi Against MCF-7 Breast Cancer Cells Haryoto, H.; Widowati, Pratiwi
Journal of Nutraceuticals and Herbal Medicine Volume 1, No. 1, Februari 2018
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (181.187 KB) | DOI: 10.23917/jnhm.v1i1.5737

Abstract

Artocarpus had been used as traditional medicine for cancer, cirrhosis, malaria, hypertension, and diabetes. This research aimed to evaluate the cytotoxic activity of methanol leaf extract of Artocarpus altilis, Artocarpus heterophyllus, and Artocarpus camansi against MCF-7 breast cancer cell. The leaf extracts of Artocarpus altilis, Artocarpus heterophyllus, and Artocarpus camansi were obtained by the method of maceration with methanol. Phytochemical screening wasperformed by Thin Layer Chromatography with the use of silica GF-254 for stationary phase and ethyl acetate: n-hexane (2:8) for mobile phase. The cytotoxic test was conducted by MTT with diverse concentrations of extract, namely 500, 250, 125, 62.5, and 31.25 μg/mL. The results of cytotoxic test were measured by ELISA reader. Based on phytochemical screening, tannin, and alkaloids were found in three extracts. Cytotoxic test demonstrated that those extracts had low cytotoxic activity against MCF-7 breast cancer cells, with IC50 of 120.85; 339.46 and 530.88 μg/mL, respectively, for Artocarpus altilis, Artocarpus heterophyllus, and Artocarpus camansi.
PENGEMBANGAN POTENSI EKSTRAK KULIT BUAH RAMBUTAN SEBAGAI BAHAN OBAT HERBAL ANTIHIPERKOLESTEROL Muhtadi, .; Haryoto, .; Sujono, Tanti Azizah; Indaryudha, Peni; Suhendi, Andi
Biomedika Vol 5, No 2 (2013): Biomedika Agustus 2013
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v5i2.266

Abstract

The rind of rambutan fruit (Nephelium lappaceum L.) has been reported to have a very strong antioxidant activity with IC50 value of 7.74 ?g / mL. The fruit contains ? avonoids and phenolic . This compounds are potentially as hypolipidemic effect. This study aims to determine the hypolipidemic effect of 96% of ethanolic extract of rind of rambutan fruit in wistar strain male rats. This research method is the pre- and post-control group design. 25 rats were divided into 5 groups. Group I (negative control) were treated by a solution of 0.5% CMC-Na, group II (positive control) were treatedby cholestyramine 0.8 kg / kg, whereas group III, IV and V treated by 96% of ethanolic extract of rind of rambutan with a dose of 125 , 250, and 500 mg / kg respectively. hiperkolesterlemia induction is done by giving a high cholesterol diet and feed for 4 weeks. High-cholesterol diet consists of cooking oil, quail egg yolk, water, PTU and feed high cholesterol consisting of margarine and standard feed. Treatment of mice was conducted for 2 weeks. The results showed that the 96% of ethanolic extract of rind of rambutan fruit with a dose of 125, 250, and 500 mg / kgbw have antihyperkolesterol activity 21.39 ± 6.61%, 31.15 ± 18.15%, and 60.75 ± 8, 26%.Keywords: Antihypercholestrol, Nephelium Lappaceum L., High-cholesterol diet
EFEK ANTIINFLAMASI EKSTRAK ETANOL KULIT KACANG TANAH (Arachis hypogaea L.) PADA TIKUS PUTIH JANTAN GALUR WISTAR YANG DIINDUKSI KARAGENIN Haryoto, Haryoto
Pharmacon: Jurnal Farmasi Indonesia Vol 11, No 1 (2010)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v11i1.63

Abstract

Kulit kacang tanah mengandung luteolin yang berpotensi sebagai antiinflamasi secara in vitro dan in vivo. Penelitian ini bertujuan untuk mengetahui efek antiinflamasi ekstrak etanol kulit kacang tanah (Arachis hypogaea L.) pada tikus jantan galur Wistar yang diinduksi karagenin Penelitian menggunakan rancangan acak lengkap pola searah. Dua puluh lima ekor tikus putih jantan galur Wistar dibagi menjadi 5 kelompok. Kontrol negatif menggunakan CMC-Na 0,5% 2,5 mL/200 gBB, kontrol positif menggunakan Na-diklofenak 6,75 mg/kgBB. Ekstrak etanol kulit kacang tanah yang diujikan yaitu dosis 50, 100 dan 200 mg/kgBB. Larutan uji diberikan secara peroral dengan volume pemberian 2,5 mL/200 gBB 1 jam sebelum kaki hewan uji diradangkan dengan karagenin 1% secara subplantar. Pengukuran volume kaki tikus dilakukan tiap 0,5 jam selama 6 jam. Data volume udem dihitung nilai AUC (Area Under the Curve) rata-rata volume udem terhadap waktu dan persen daya antiinflamasi. Data dianalisis dengan anava satu jalan dan dilanjutkan uji LSD (Least Significant Difference) dengan taraf kepercayaan 95%.  Hasil penelitian menunjukkan bahwa ekstrak etanol etanol kulit kacang tanah (Arachis hypogae L.) dengan dosis 50, 100 dan 200 mg/kgBB mempunyai persen daya antiinflamasi berturut-turut sebesar 16,33%; 26,39% dan 31,70%, sedangkan Na-diklofenak 6,75 mg/kgBB sebesar 32,24%.Kata kunci: kulit kacang tanah (Arachis hypogaea L.), ekstrak etanol, antiinflamasi
Cytotoxic Activities of Ethanol Extract, Nonpolar Semipolar, and Polar Fractions of Dioscorea esculenta L.) on MCF7 Cancer Cell Haryoto, H
Journal of Nutraceuticals and Herbal Medicine Vol 1, No 1 (2019): JNHM 2019
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (546.39 KB) | DOI: 10.23917/jnhm.v2i1.7853

Abstract

One of the disease that have a high contribution to the death of women in the world is breast cancer. It leads to the research and exploration to find its cure. This study is conducted to know the anti-cancer activity onethanol extract, nonpolar, semipolar, and polar fractions of lesser yam (Dioscorea esculenta L.) herbs. It also aims to find out the content of compound on semipolar fraction Dioscorea esculenta L. herbs. The extraction was carried out using maceration technique with 96% ethanol as solvent. Then, the fractination was done using vacuum liquid chromatography method with n-hexane and acetone as mobile phase with the ratio of 9:1, 8:2, 7:3, 6:4, and 5:5. After that, the phytochemical test was undertaken using the thin layer chromatographywith n-hexane and acetone as mobile phase with proportion 7:3. Meanwhile, the cytotoxic test was conducted using MTT assay method with IC50calculation was counted using linear regression between the log concentration and the percentage of living cells. The semipolar fraction of Dioscorea esculenta L. herbs has IC50value of 632,42 µg/mL, whereas the ethanol extract, nonpolar and polar fractions have the IC50 value 1000 µg/mL. Furthermore, the compound of the semipolar fraction of Dioscorea esculenta L. herbs are saponins, terpenoids, alkaloids, and phenolics.
Cytotoxic Assay of Semipolar Fraction Of Ethanolic Extract From Sugar Apple (Annona Squamosa L.) Stem Bark on T47D Cells Muflihah, Cita Hanif; Haryoto, Haryoto; Indrayudha, Peni
Pharmacon: Jurnal Farmasi Indonesia Vol 17, No 2 (2020)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v17i2.12268

Abstract

Previous research has shown that some compounds in leaves and seeds of sugar apple have a cytotoxic activity. The aim of this research was to determine the cytotoxicity of semipolar fraction of ethanolic extract from sugar apple stem bark (Annona squamosa L.) on T47D cancer cells. The semipolar fraction of ethanolic extract from sugar apple stem bark was collected by fractionation using Vacuum Liquid Chromatography (VLC) with hexane:ethyl acetic (9:1, 8:2, 7:3, and  6:4)  as  mobile  phase.  Cytotoxicity from the fractions of five different concentration namely; 25, 50, 100, 150, and 250, µg/mL was measured by MTT assay. The potency of the cytotoxicity was defined by the ability of the fraction to inhibit the growth of T47D cells indicated by the value of IC50. Qualitative analysis of contained compounds in the fraction was done by Thin Layer Chromatography (TLC) method using silica gel F 254 as a stationary phase and hexane:ethyl acetic (7:3) as a mobile phase. UV 254 and 366 nm lamp also Dragendorff, citroboric, and FeCl3 spray reagents were used to visualize the spots of the secondary metabolites. The result proved that the semipolar fraction of ethanolic extract from sugar apple stem bark showed potential cytotoxicity on T47D cancer cells with IC50value of 70,77 µg/mL. Qualitative analysis showed that the fraction contained flavonoids and alkaloids which is presumably responsible for its cytotoxic activity. 
Business Development of Cumi-cumi Product Made from Sweet Potatoes in Karangbangun Village, Karanganyar Regency Rauf, Rusdin; Haryoto, Haryoto
Journal of Community Services and Engagement Vol 1, No 1 (2020): JCSE 2020
Publisher : Muhammadiyah University Press

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The program of community service began with the socialization of applications on the village government and partners. Furthermore, it introduced machinery/technology to create technology on partners. The purpose of the community service activity was to provide the skills in the production of cumi-cumi products from sweet potato to members of Aisyiyah, PKK, and Karang Taruna in Karangbangun Village - Karanganyar District. The community service program began with a socialization program by the village government and partners. Furthermore, machines and technology were introduced to partners. The training of cumi-cumi product making and packaging was given to the partners, as well as production assistance, to ensure that partners were skilled at processing the products independently. The results showed that the partners were skilled at producing cumi-cumi products and using the machines. Two new UMKMs were formed in the community service program. Partners have been packing the products with labeled, marketed the products locally, as well as getting income from these sales.
Co-Authors . MUHTADI A Anifatussaa'dah abdul, ahwan Aditya Naova Sofyan Ady Irawan Aflit Nuryulia Praswati Agustono Wibowo Agustono Wibowo Ahmad Fauzi Ahmad, Farhand Ahwanti Rukdiatma Nur’aini Alfa Frista Alvira Efendi Amalia Suci Medisusyanti Amalia, Dina Ayu Amaliyah Dina Anggraeni Andi Suhendi Andi Suhendi Ani Syafriati Anifatussaa'dah, A Anis Siyama Annisa Meyndra Komala Aprilianingtyas, Tri Ardalia Rinanda Oktaviani Ardiyani, Diah Siwi Arly Syahputri , Janies Auliya, Dhiyahul Azzahra, Hanifa Putri Bama, Samsun Ari Basusena, Rahardian Surya Bela Purnama Dewi Brillian Nur Diansari Broto Santoso Burhanudin Ichsan Cast Torizellia Chairunnisa, Alya Chandra Wisnu Utomo Cita Hanif Muflihah Citra, Tia Mella Danang Raharjo Danang Raharjo Danang Raharjo Dewi, Triana Ariska Diah Siwi Ardiyani Dina Ayu Amalia Dinda Nurochmah Mujiyati Dwi Bagus Pambudi Dwi Sarbini Dyah Rahmawatie Ratna Budi Utami Dyera Forestryana Dzafira, Laila Eka Lusia Erika Nuur Anisa Putri Erlinda Novita Sari Erna Herawati Erna Herawati, Erna Euis Holisotan Hakim Fahriza Mei Trihatmoko Fahrun Nur Rosyid Faridita khoirun Nisa' Fida' Husein Fida’ Husain Fidhia Nur Rifaini Firdaus, Gita Firstca Aulia Rachma Fitriani, Rizki Ainun Frida Rosenova Gita Firdaus Gita Firdaus Hafid Nugroho Hafiz Ramadhan Hafiz Ramadhan Haliza Arzeti Nurseptiria Hapsari, Atikah Haya Nabilah Utama Heng Yen Khong Henggar Prasetyo Wikan Saputro Herda Ariyani HI, Marsilia Rosa Sinensis Hidayah Karuniawati Ichsan, Burhanudin Ida Maesaroh Ida Maesaroh, Ida Jalifah Latip Joko Kristianto Keisya, Aulita Khusnul Khotimah khusnul khotimah Kosworo Kosworo Kusumastuti, Lina Ayu Laila Dzafira Leni Wijaya Lia Dewi Juliawaty Lina Ayu Kusumastuti Listiana Masyita Dewi Listyana Dewi Prastiwi Lusia, Eka Luthfiyyah Amalia Zahra Mariska Sri Harlianti Marlupi Dwi Lestari Marsilia Rosa Sinensis HI Marsya, Vitania Maryatun maryatun maryatun Maulida Nur Ikhsan Medisusyanti, Amalia Suci Muhammad Irfan Muhammad Irfan Muhammad Priyadi Muhtadi Muhtadi Muhtadi, M Munti Sarida Muslihah, Sayyidah Nurul Mustika, Yurnanda Ambar Niati Ambarsari Nisa', Faridita khoirun Nugroho Adi Suseno Nurany, Asfy Nursalinda Kusumawati Nurseptiria, Haliza Arzeti Nuryanti, Yulia Dwi Nur’aini, Ahwanti Rukdiatma Oktaviani, Ardalia Rinanda Peni Indaryudha, Peni Peni Indrayudha Pramudya Kurnia Pratiwi Widowati Puguh Ika Listyorini Putri Agustina Putri, Annisa Nur Lathifah Amanda Putri, Erika Nuur Anisa Putri, Sendy Pradila Raafika Studiviani Rahardian Surya Basusena Rasyid Abdul Retna Dewi Lestari Rifaini, Fidhia Nur Riska Rosita Rizki Ainun Fitriani Rosnah, Rosnah RR. Ella Evrita Hestiandari Rusdin Rauf Sabar Narimo Saputri, Luki Rahmadani Tulus Sayyidah Nurul Muslihah Sekarsari, Devina Sendy Pradila Putri Shofa, Ghoitsa Nabila Sjamsul Arifin Achmad Studiviani, Raafika Suranto Suranto Suranto Suranto, Choirun Nisa Sutama Syifa Aulia Paramitha Tanti Azizah Tanti Azizah Sujono Tanti Azizah Sujono Tanti Azizah Sujono Tia Mella Citra Tista Ayu Fortuna Tri Aprilianingtyas Triana Ariska Dewi Trihatmoko, Fahriza Mei Trinanda, Edtano Utama, Haya Nabilah Utomo, Chandra Wahyu Vitania Marsya Widowati, Pratiwi Wildan Firdaus, Muhammad Yana Maolana Syah Yulia Dwi Nuryanti Yuliana Dwi Jayanti Yurnanda Ambar Mustika Zahrah Luthfiatul Fadhilah