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Medicinus : Jurnal Kedokteran
  • Medicinus : Jurnal Kedokteran
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Published by Universitas Pelita Harapan
ISSN : 19783094     EISSN : 26226995     DOI : -
Core Subject : Health,
Medicine & Pharmacology Public Health
Medicinus: Jurnal Kedokteran is an official journal of the Faculty of Medicine, Universitas Pelita Harapan launched in the year 2007. Medicinus is a peer-reviewed and open-access journal that covers basic, translational, or clinical aspects of health and medical science. Medicinus accepts original research articles, review articles, and also interesting case reports. Medicinus: Jurnal Kedokteran is published three times a year in February, June, and October.
Arjuna Subject : -
Articles 429 Documents
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Prevalence and Risk Factors of Occupational Contact Dermatitis in Healthcare Workers Enggalhardjo, Muljani; Setiawan, Alan Dwi; Christianto, Putra Niko Laksamana Oceano
Medicinus Vol. 13 No. 3 (2024): June
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v13i3.8886

Abstract

Background: Occupational contact dermatitis (OCD) is prevalent among healthcare workers, especially during the COVID-19 pandemic. Symptoms include dryness, itchiness, and redness, with hands being the most affected. Risk factors include frequent hand washing, increased glove use, allergies, and lack of health and safety training. This review emphasizes the need for targeted prevention strategies and awareness programs.Methods: We conducted a systematic review using PubMed, focusing on studies involving healthcare workers and OCD. Keywords included "occupational contact dermatitis," "contact dermatitis," "healthcare workers," and "risk factors for OCD." Data were collected using a structured, interviewer-administered questionnaire, including the Nordic Occupational Skin Questionnaire (NOSQ-2002).Result: The review included 2,706 healthcare workers. Hand dermatitis was the most common, affecting 22% of participants. Key risk factors were a personal history of allergies, frequent hand washing, high glove usage, and insufficient health and safety training.Conclusions: This review identifies significant risk factors for OCD among healthcare workers, highlighting the need for interventions focused on reducing hand washing frequency, managing glove use, and improving health and safety training.
Sudden Onset of Diabetic Ketoacidosis in a Patient with Discordant HbA1C: A Unique Case of Fulminant Type 1 Diabetes Mellitus (FT1DM) in a Middle-aged Man Nadine, I Gusti Ayu; Siregar, Jeremia Immanuel; Prasetya, Yonesha Rahmania
Medicinus Vol. 13 No. 3 (2024): June
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v13i3.8887

Abstract

Introduction: Diabetic Ketoacidosis (DKA) is an acute complication of diabetes mellitus (DM) which present as the first manifestation in fulminant type 1 diabetes mellitus (FT1DM) without significant elevation of HbA1C. We present a unique case of a 52-years-old male with DKA without previous history of DM and HbA1c of 6.6.Case Illustration: A 52-years-old male was brought to hospital due to persistent vomiting. He experienced polyuria and unexplained weight loss but denied previous history of DM. He was diagnosed with DKA due to his blood glucose of 1107 mg/dL along with elevated blood ketone and metabolic acidosis. However, his HbA1c was a mere 6.6. His serum lipase was increased, consistent with pancreatic damage. He was then discharged with basal-bolus insulin.  Discussion: Although the symptoms of this patient was consistent with hyperglycemic crisis, the presentation of DKA is usually associated with elevated HbA1c, approximately 10.4 - 16.9%. This unusual HbA1c points to the diagnosis of FT1DM. It is caused by sudden beta-cell destruction triggered by viral infections, alongside genetic disposition, leading to sudden depletion of insulin occurred less than a week and presents with ketoacidosis. It is characterized by low HbA1c (< 8.7%) yet extremely high blood glucose (‰¥ 288 mg/dl) and elevated pancreatic enzymes (depicting pancreatic damage). A diagnosis of FT1DM can be ascertained in this patient as his presentations matches its characteristics.Conclusion: FT1DM is a sub-type of T1DM which can suddenly occur in patients and associated with discordant HbA1c. It is important to recognize and treat it accordingly to avoid fatal outcomes.
Uncommon Presentation of Perianal Condyloma Acuminata in a Young Male: A Case Report Christina, Natalia Maria; Prasetyo, Patricia Diana; Cendikiawan, Albert; Wijaya, Jeremiah Hilkiah
Medicinus Vol. 13 No. 3 (2024): June
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v13i3.8888

Abstract

Background: Perianal warts, also known as anogenital warts or condyloma acuminata, represent a significant health concern in the young male population. Here, we present a unique case of a large perianal wart in a 26-year-old male patient.Case Description: The patient came to the surgical clinic with complaints of an anal lump for 7 months ago. The lump first appeared in February 2019 as big as a green bean, it increased in size, bled easily and painful to be touched. The patient had a history of anal intercourse 1 month before the lump appeared. The lump size was about 8 x 5 cm and resembled “cauliflower”. Diagnosis of suspected anal papilloma was made.  In July 2019, an incisional biopsy was performed, and the result showed papilloma squamosa with condyloma acuminata as a differential diagnosis. In September 2019, perianal soft tissue tumor excision with advancement flap was performed and the result showed condyloma acuminata. Discussions: The case highlights the importance of careful evaluation and diagnosis in such clinical scenarios, as the initial diagnosis of anal papilloma was later refined to condyloma acuminata based on the biopsy and surgical findings. Early detection and appropriate management are crucial in cases like this to ensure the best possible patient outcomes.
Age, Onset, and Tumor Size Differences in Newly Diagnosed Breast Cancer Patients Before and During the SARS-CoV-2 Pandemic at Siloam Hospital Lippo Village (April 2019 - December 2020) Halim, Freda Susana
Medicinus Vol. 13 No. 3 (2024): June
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v13i3.8889

Abstract

Background: The current pandemic condition has caused delays in cancer treatment therefore surveillance should be increased.Methods: By total sampling, this retrospective cross-sectional study enrolled 108 samples, who were newly diagnosed breast cancer patients at the outpatient department of Siloam Hospital Lippo Village (April 2019 - December 2020). Data obtained from medical records and interviews from December 2020 - February 2021.Result: From the total of 108 samples which consisted of 54 samples before the pandemic (April 2019 - February 2020) and 54 samples during the pandemic (March 2020 - December 2020), accompanied by an increasing trend. The age during pandemic was younger than before pandemic (51,167 years old ± 11,255 vs 47,537 years old ± 9,824, p value=0,038), the tumor size during pandemic was bigger than before pandemic (3,403 cm ± 3,024 vs 4,262cm ± 4,212, p value=0,046) but the onset of patient during pandemic was not longer than before pandemic (281,69 days ± 401,387 vs 178,09 days ± 292,563, p value=0,036).Conclusions: Newly diagnosed patients have younger age and larger tumor size during pandemic when we compare to before pandemic period, but no difference in onset term. Surveillance to society is needed to ensure older people with smaller tumor size to seek medical attention.
Intracranial Solitary Fibrous Tumor in a 25-Year-Old Woman Prasetyo, Patricia Diana; Marisca, Stephanie; Wahjoepramono, Eka J.
Medicinus Vol. 13 No. 3 (2024): June
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v13i3.8890

Abstract

Introduction: Intracranial solitary fibrous tumors (ISFTs) are extremely rare spindle cell tumors originating from dendritic mesenchymal cells expressing CD34 antigens that are usually benign, although malignant transformation had been reported. The knowledge of natural course and prognostic factors of ISFTs is still limited and the tumor is easily misdiagnosed.Case Presentation: An intra-cranial extra-axial tumor tissue resection from a 25-year-old woman was evaluated in the Surgical Pathology Laboratory. Histologic findings (cellular spindle cell tumor with ”˜patternless’ pattern, staghorn blood vessels and <5 mitoses per 10 hpf) and immunophenotype (positive for CD34, weakly and focally positive for STAT6) suggested a diagnosis of intracranial solitary fibrous tumor WHO Grade II.Discussion: ISFTs have very low incidence in the CNS and are difficult to distinguish radiologically from meningiomas, thus post operative pathological examination and immunohistochemistry markers evaluations are the mainstay for diagnosis. ISFT is associated with NAB2-STAT6 gene fusion and may exhibits a wide spectrum of histological features. STAT6 immunohistochemistry is considered as one of the most sensitive diagnostic methods, while the evaluation of CD34 expression can be used as alternative diagnostic method despite having lower sensitivity.
The Relationship of Body Mass Index with Length of Stay in Acute Appendicitis Patients Who Have Undergoing Open Appendectomy at RSUS Lippo Village Karawaci Hospital Christianto, Putra Niko Laksamana Oceano; Sudirman, Taufik
Medicinus Vol. 14 No. 1 (2024): October
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v14i1.9194

Abstract

Background : Appendicitis is an inflammation that occurs in the veriform appendix. The Indonesian Ministry of Health announced that the number of inpatients with appendicitis is the fourth most common disease in Indonesia. Open appendectomy is a procedure for treating appendicitis. Patients who have an open appendectomy procedure require hospitalization for the wound to heal. Various studies have been conducted to find a relationship between body mass index and length of stay in patients with appendicitis but have different results, besides that research on this topic is still minimal in Indonesia. Therefore, this study was conducted to analyze the relationship between body mass index and length of stay in acute appendicitis patients who had undergone open appendectomy. Methods : This study used a cross-sectional study design with a sample population of acute appendicitis patients at Lippo Village Hospital Karawaci. 182 samples were selected using a purposive sampling technique. The research sample data was taken from the patient's medical records and will be tested for analysis using SPSS 25 with the Kruskal Wallis ANOVA method. Result : From 182 research samples, it was found that the median length of stay of patients with different body mass indexes was 3 days. Based on the Kruskal Wallis ANOVA test, there was no significant elationship between gender and length of stay (p > 0.05). Conclusions : This study shows that there is no relationship between body mass index and length of stay in acute appendicitis patients who have undergone open appendectomy.
The Relationship Between Big Five Personality Traits and Academic Performance of Asian Medical Students Lauren, Stefani; Nathania, Jocelyn; Wijayanto, Rhendy; Wijaya, Ratna Sari
Medicinus Vol. 14 No. 1 (2024): October
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v14i1.9198

Abstract

Introduction : Personality traits have been shown to influence the individual’s critical thinking, learning strategies, and motivation, resulting in the overall student’s academic performance. Academic performance is an important factor among medical students to ensure their success in long-term medical education, training and work performance as medical doctors. This study aims to evaluate the relationship between personality traits and academic performance among medical students. Methods : The study was conducted among preclinical medical students from the Medical Schools of Pelita Harapan University, Indonesia. The personality traits were assessed using the NEO Five-Factor Inventory-3 (NEO-FFI-3), which consists of 60 items assessing the five personality traits (neuroticism, extraversion, openness, agreeableness, and conscientiousness). The academic performance was evaluated using the cumulative grade point average (CGPA) score. Results : A total of 224 participants were included in this study. The mean age of the participants was 19.8 years old (SD±1.3). Neuroticism was the predominant personality trait among medical students and was found to be negatively associated with CGPA in univariable and multivariable analyses (p<0.05). Conclusion : This study reveals that neuroticism personality traits are prevalent among preclinical medical students and adversely affect their academic performance. Understanding the general personality traits present among medical students and its relationship with academic performance can provide valuable input for further medical education programme development.
Pap Smear Practices among Female Healthcare Professionals in Indonesia and Their Associated Factors Ramli, Richelle; Angelina
Medicinus Vol. 14 No. 1 (2024): October
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v14i1.9226

Abstract

Introduction : Cervical cancer is the fourth most frequent disease in women worldwide. However, pap smear coverage in Indonesia remains below the target. The purpose of this study was to describe pap smear practice among female healthcare professionals and its associated factors. Methods : This cross-sectional study was conducted from August 2022 to June 2023 among married female healthcare professionals of reproductive age who worked in Kelapa Dua district, Tangerang, Banten, Indonesia. Three general hospitals, two primary clinics, and one community health center were involved in this study. Data was collected using a self-administered questionnaire and analyzed using a chi-square test. Results : From 236 respondents, only 80 respondents (33.9%) had pap smear tests. The most common reasons for not doing the test were lack of time and having not experienced any of the symptoms. Those who were doing the pap smear tests were likely to be more than 40 years old (OR 29.900; 95% CI 9.595 – 93.172; p<0.001), married for more than 10 years (OR 28.737; 95% CI 9.955 – 82.955; p<0.001), multiparous (OR 6.941; 95% CI 2.706 – 17.805; p<0.001), and have higher economic income (OR 7.333; 95% CI 1.443 – 37.274; p=0.020). Female healthcare professionals other than medical practitioners, nurses, or midwives were less likely to do the pap smear tests (OR 0.370; 95% CI 0.167 – 0.823; p=0.02). Conclusion: Pap smear practice among female healthcare professionals in Indonesia was inadequate. Age, marriage duration, parity status, types of healthcare professionals, and socioeconomic status were significantly associated with pap smear practice.
Relationship Between the Level of Knowledge and Attitude Towards Maternal Behavior of Stunting Prevention at Bojong Nangka Community Health Center in Tangerang District Tanara, Arron; Rivami, Dwi Savitri
Medicinus Vol. 14 No. 1 (2024): October
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v14i1.9229

Abstract

Background: Stunting is one of the major health problems in Indonesia. In 2022, the prevalence of stunting in Indonesia was 21.6%, and there were still 9,200 cases of stunting in Tangerang District alone. Stunting prevention can be done since pregnancy. It is estimated that stunting prevention behaviors among pregnant women is related to their knowledge and attitudes. Puskesmas Bojong Nangka was a community health center in Tangerang that treated stunting but has no data on this matter. Methods: This study used a cross-sectional study design. Data on the level of knowledge, attitudes, and behaviors in stunting prevention was collected using questionnaires and further was analyzed using the Chi-square test. Result: From 96 respondents, it was found that the majority (63.5%) had a good level of knowledge on stunting prevention. Most respondents also had a good attitude towards stunting prevention (83.3%). There were 72 respondents (75%) who had recommended stunting prevention behaviors. Bivariate analysis showed that there was a significant relationship between knowledge level and stunting prevention behaviors (P value < 0.001; OR 7.29; 95% CI 2.6 – 20.39) but there was no significant relationship between attitudes and stunting prevention behaviors (P value = 1; OR 1; 95% CI 0.29 – 3.45). Conclusions: There was a significant relationship between the level of knowledge towards stunting prevention behaviors among pregnant women at Bojong Nangka Community Health Center, Tangerang District.
Characteristics of COVID-19 Therapy Based on Disease Severity at Siloam Kebon Jeruk Hospital Tjahyanto, Teddy; Herwanto, Velma
Medicinus Vol. 14 No. 1 (2024): October
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v14i1.9233

Abstract

Introduction : COVID-19 is an infectious disease that can cause acute respiratory syndrome by droplet transmission. Along with the very fast spread of the virus which occurs in almost all countries, it is necessary to have therapies that can reduce the morbidity and mortality of patients infected with COVID-19. Various factors affect the administration of therapy so a management guideline is needed for medical personnel so that the administration of therapy can be consistent and efficient in accordance with scientific evidence. This study aims to determine the characteristics and therapeutic options of COVID-19 patients based on the severity of the disease so it can be an evaluation for policymakers and health workers in providing COVID-19 therapy. Methods : This type of research is descriptive, and the research design is cross-sectional with a total population sampling. The study was conducted at Siloam Kebon Jeruk Hospital with a total of 135 respondents from secondary medical record data. Results : The observed data include the characteristics of the respondents and the therapies for COVID-19 patients, which consist of antiviral, anti-inflammatory, and anticoagulant treatments. Based on the collected data, COVID-19 patients were predominantly male (55.6%) with an average age of 55 years. Many patients presented with moderate severity without requiring oxygen (34.1%) and were classified as having referred outcomes (47.4%). Antiviral therapy using favipiravir was predominantly administered to patients with mild to moderate severity, while remdesivir was mostly given to those with moderate to severe severity. Corticosteroids, such as dexamethasone and methylprednisolone, were the preferred choice for anti-inflammatory therapy (72.2%). Heparin was the most commonly used anticoagulant therapy across all severity levels, and antibiotics were administered to the majority of patients infected with COVID-19 (73.3%). Conclusions : Evaluation of the low rate of use of corticosteroids and anticoagulants in COVID-19 patients is needed.

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