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INDONESIA
Indonesian Journal of Medicine
Published by Universitas Sebelas Maret
ISSN : -     EISSN : 25490265     DOI : -
Core Subject : Health,
Medicine & Pharmacology Public Health
Indonesian Journal of Medicine (IJM) is an international, open-access, and double-blind peer-reviewed journal, focusing on the intersection of biomedical science, clinical medicine, and community medicine. The journal began its publication on August 20, 2015, and is published online three times yearly. It is academically designed for all physicians, health researchers, and health care professionals, regardless of their medical specialties, or type of employment.
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Articles 8 Documents
 1 
Search results for , issue " Vol 2, No 3 (2017)" : 8 Documents clear
Does HBA1C Correlate with Lipid Profile in Type 2 Diabetes Mellitus? A New Evidence from Medan, North Sumatera Julianto, Endy; Silitonga, Hendrika Andriana; Siahaan, Jekson Martiar
Indonesian Journal of Medicine Vol 2, No 3 (2017)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: Diabetes mellitus (type 2 DM) is now ranked first in health problems and its prevalence tends to increase worldwide. The Diabetes Control and Complication Trial (DCCT) study showed that lowering HbA1c rates may delay or prevent chronic complications. One of the risk factors for CHD in type 2 DM is dyslipidemia, i.e lipid metabolism disorders in the form of elevated total cholesterol, triglyceride (TG), low-density lipoprotein (LDL), and decreased levels of high-density lipoprotein (HDL). This study aimed to determine the correlation between HBA1C and blood sugar, as well as the lipid profile in patients with type 2 DM.Subject and Methods: This was an analytic observational study with a cross-sectional design. The study was conducted at the Endocrinology and Metabolic polyclinic Pirngadi Hospital, Medan, North Sumatera, from January to February 2018. A total sample of 10 patients diagnosed with type 2 diabetes mellitus with obesity was selected for this study. The independent variables were blood sugar, lipid profile including total cholesterol, high-density lipoprotein (HDL), low-density lipoprotein (LDL), and triglyceride. The dependent variable was the HbA1c level. Lipid profile was measured by blood serum examination. HbA1c level was measured by blood serum examination. The data were analyzed by Pearson correlation.Results: Hba1c was positively correlated with blood sugar levels and was statistically significant (r= 0.81; p= 0.005). HbA1c correlated weakly and was statistically non-significant with total cholesterol (r= 0.14, p= 0.702), LDL (r= 0.15; p= 0.683), HDL (r= 0.04; p= 0.922), and triglycerides (r= 0.06; p= 0.860).Conclusion: HbA1c correlates with blood sugar levels but does not show a correlation with lipid profiles.Keywords: HBA1C, lipid profile, blood sugar, type 2 diabetes mellitusCorrespondence:Endy Julianto. Department of Parasitology, Faculty of Medicine, Methodist University, Medan.Indonesian Journal of Medicine (2017), 2(3): 207-212https://doi.org/10.26911/theijmed.2017.02.03.08
The Effect of Complementary Vitamin D on Sputum Conversion in Pulmonary TB Patients Lubis, Nita Andriani
Indonesian Journal of Medicine Vol 2, No 3 (2017)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: Pulmonary TB is one of the most important health problems in Indonesia. The number of pulmonary TB patients ranked second after India. Vitamin D has a complex effect in the immune system. One of the effects of vitamin D is to stimulate the production of Cathelicidin which increases macrophage phagocytosis. This study aimed to analyze the effect of complementary vitamin D on sputum conversion in pulmonary tuberculosis patients.Subjects and Method: This study was a randomized controlled trial conducted at several health centers in Deli Serdang, North Sumatera, from November 2015 to June 2016. A total sample of 80 patients with positive acid-resistant bacilli (BTA) was selected for this study by consecutive sampling. The sample was allocated randomly into two groups: (1) TB drug group + 2.5 mg vitamin D; (2) TB drug group + placebo. The dependent variable was sputum conversion. The independent variable was complementary vitamin D. Pre and post vitamin D levels were examined by ELISA technique. Sputum conversion was examined by TB laboratory worker at the health center where patients received TB drug treatment. Difference in percent of sputum conversion between the two groups was tested by chi-square test. Difference in mean of sputum conversion time between the two groups was tested by t-test.Results: The mean serum vitamin D level in the intervention group (62.05±22.08) was higher than the control group (28.56±7.48) after the intervention, and it was statistically significant (p<0.001). After 56 days, all subjects in the vitamin D group experienced sputum conversion (100%) with a median sputum conversion time of 28 days, whereas 90% of subjects in the placebo group experienced sputum conversion with a median sputum conversion time of 48 days (p= 0.002).Conclusion: Adding vitamin D to anti-TB drug treatment effectively improves and accelerates sputum conversion of patients with tuberculosis acid-fast bacilli smear positive.Keywords: Vitamin D, sputum conversion, pulmonary tuberculosisCorrespondence: Nita Andriani Lubis. Department of Health Analysis, School of Health Polytechnics Medan, North Sumatera. Jl. William Iskandar Pasar V Barat No. 6 Medan 20137, North Sumatera, Indonesia. Email: taufik.abay.mumtaz@gmail.com.Indonesian Journal of Medicine (2017), 2(3): 169-174https://doi.org/10.26911/theijmed.2017.02.03.04
Clinical and Functional Outcomes of Patients Undertaking Posterior Cruciate Ligament (PCL) Reconstruction Using Standard and Posteromedial Portal Fixation Paramita, Dyah; Solahudin, Rhatomy
Indonesian Journal of Medicine Vol 2, No 3 (2017)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: Currently handling patients with posterior cruciate ligament (PCL) injury is still controversial. Arthroscopic techniques can reduce surgical morbidity and allow for an earlier and aggressive rehabilitation program. This study aimed to evaluate the clinical and functional outcomes of patients with isolated PCL ruptures undergoing PCL reconstruction with PCL residual, tendon hamstring autopsies, standard portable interference fixation, and posteromedial.Subjects and Method: This was a retrospective cohort study conducted at Dr. Soeradji Tirtonegoro Hospital, Klaten, Central Java. A total sample of 6 patients with isolated PCL rupture was selected for this study. The independent variables were PCL reconstruction with PCL residual, autologous tendon hamstring, standard portal interference fixation, and posteromedial for 9 months (range 5-17 months). The dependent variable was clinical and functional outcomes, which were measured by the International Knee Documentation Committee (IKDC), Knee Society Score, Tigner Lysholm Knee rating scale, and a modified Cincinnati Assessment System Questionnaire. Scores of clinical and functional outcomes before and after surgery were tested by t-test.Results: The Tigner score after surgery (mean = 94.50; SD = 4.18) was higher than before surgery (mean = 63.17; SD = 12.48) with p = 0.001. The IKDC score after surgery (mean = 81.48; SD = 10.12) was higher than before surgery (mean = 55.73; SD = 18.72) with p = 0.014. Cincinnati modification score after operation (mean = 92.83; SD = 8.11) higher than before surgery (mean = 66.17; SD = 13.23) with p = 0.002. The Knee Society Score after surgery (mean= 82.16; SD= 4.91) was higher than before surgery (mean= 60.83; SD= 10.51) with p= 0.001. The percentage of patients with knee stability according to Lysholm score after surgery (6 patients, 100%) was higher than before surgery (3 patients, 50%).Conclusion: PCL reconstruction with PCL residual, autologous tendon hamstring, standard portal interference fixation, and posteromedial for 9 months can improve clinical and functional outcomes in patients with isolated PCL ruptureKeywords: posterior cruciate ligament, portal posteromedial, reconstructionCorrespondence: Paramita Dyah Lasmana. Department of Orthopedics and Traumatology, Dr. Sardjito General Hospital/Faculty of Medicine, Universitas Gadjah Mada, Yogyakarta, Indonesia. Email: meetha_dyah@yahoo.com. Mobile: +6282137543690.Indonesian Journal of Medicine (2017), 2(3): 175-183https://doi.org/10.26911/theijmed.2017.02.03.05
Epithelial Rate Difference on Donor Wound of Split Thickness Skin Graft in the Thigh Area by Applying Leukocrepe® and Medicrepe® Rinaldi, Ivan; Sungkar, Amru; Alifianto, Untung
Indonesian Journal of Medicine Vol 2, No 3 (2017)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: applying split thickness graft (STSG) is as one of the reconstruction techniques and it is often conducted. Applying the technique creates superficial wound on the donor wound or it is known by donor site. The elastic bandage usage is one of the tools which is used in giving treatment to donor site as a standard operational procedure treatment at Dr. Moewardi hospital (RSDM) Surakarta. RSDM Surakarta has not had clinic test yet to compare between applying elastic bandage Leukocrepe® and Medicrepe® on wound care STSG on the thigh area.Subject and Method: The study used post-test only control group design with the total of the sample was 18 patients. The study was conducted in intermediate STSG donor wound with 0.018 inches thickness on the lateral thighs. By dividing two donor wounds, a half-sided of upper part was bandaged by applying Leukocrepe® and the other half of the lower part was bandaged by Medicrepe®. After that, epithelialization score was conducted on the seventh day. All the data then were collected and after that the data were tested by applying Wilcoxon rank test.Result: according to the study conducted to 18 patients of plastic surgery section at RSUD Dr. Moewardi during November 2016-Juni 2017, the result showed that the epithelialization chart was approximately 61.39 ± 30.05% for STSG donor wound on the lateral thighs part and it was done on the seventh day by applying Leukocrepe, meanwhile applying Medicrepe, the result was approximately 43.67 ± 30.69 %. The mean score of epithelialization applying Medicrepe® was more significant than applying Leukocrepe® and it showed that there was significantly different statistically with the score (p<0.001).Conclusion: According to the result above, it can be seen that the STSG donor wound care on the thighs using Medicrepe® is more effective in accelerating epithelialization process than the one which is applied by Leukocrepe®.Key Word: Epithelization, Elastic Bandage, Medicrepe®, Leukocrepe®Correspondence: Ivan Rinaldi. Public Surgery Resident of Medical Faculty of UNS. Email: ivanmudfin@gmail.com.Indonesian Journal of Medicine (2017), 2(3): 146-153https://doi.org/10.26911/theijmed.2017.02.03.01
Survival Predictors of People Living with HIV/ AIDS in Wamena, Papua Kogoya, Tena; Demartoto, Argyo; Murti, Bhisma
Indonesian Journal of Medicine Vol 2, No 3 (2017)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: Quality of life (QoL) is an important component in the evaluation of the well-being of people living with HIV and AIDS (PLWHA), especially with the appreciable rise in the longevity of PLWHA. The analysis of the quality of life is essential for the healthcare policies and services directed toward PLWHA, since this indicator values the perception of people about their own life and health. However, little is known about the determinant of QoL in PLWHA in Papua. The aim of this study was to analyze survival predictors of people living with HIV/ AIDS in Wamena, Papua, Indonesia.Subjects and Method: This was a retrospective cohort study conducted in Wamena Hospital, Papua, from December 2017 to February 2018. A cohort of 304 PLWHA was selected for this study from the medical record at Wamena Hospital. The dependent variable was survival. The independent variables were adherence to ART, nutritional status, age, and coinfection. The data were collected from medical record and questionnaire. The data were analyzed by Cox regression model.Results: The risk of dying of PLWHA if adherent to take the ART was lower than not adherent to take the ART (HR=0.45; 95% CI= 0.06 to 0.33; p= 0.002).The risk of dying of PLWHA with poor nutritional status was higher than good nutritional status (HR= 12.78; 95% CI= 6.81 to 23.98; p< 0.001). The risk of dying of PLWHA aged ?35 years was slightly higher than <35 years (HR= 1.47; 95% CI= 1.00 to 2.17; p= 0.050). The risk of dying of PLWHA with coinfected was higher than without coinfected (HR= 1.59; 95% CI= 1.15 to 2.23; p= 0.006).Conclusion: The risk of dying of PLWHA decreases if adherent to take the ART, but increases with poor nutritional status, age ?35 years, and coinfection.Keywords: survival, adherence to treatment, people living with HIV/ AIDS.Correspondence:Tena Kogoya. Masters Program in Public Health, Universitas Sebelas Maret, Jl. Ir. Sutami No. 36 A, 57126, Surakarta, Central Java. Email: tena.kogoya76@gmail.com. Phone: +628198869665.Indonesian Journal of Medicine (2017), 3(2): 184-191https://doi.org/10.26911/theijmed.2017.02.03.06
Serum Ferritin as a Predictor of Shock in Children with Dengue Infection Evalda, Putri; Soebagyo, Bambang; Riza, Muhammad
Indonesian Journal of Medicine Vol 2, No 3 (2017)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: Dengue shock syndrome causes high morbidity and mortality among children worldwide. Several laboratory monitoring can be used to evaluate the progressivity of dengue virus infection. This study aimed to analyze ferritin serum as a predictor of shock in children with dengue infection, and to determine the cut off point that can be used to diagnose dengue shock.Subjects and Method: This was a cross sectional study conducted at pediatric ward, Dr. Moewardi hospital Surakarta Dr. Soetrasno hospital Rembang, Central Java. Study population was children aged less than 18 years old with dengue infection. Study subjects were selected by consecutive sampling. Tha dependent variable was dengue shock. The independent variable was serum ferritin concentration. Mann Whitney test was used to compare mean ferritin concentration between children with and without dengue shock. Cut off point of serum ferritin concentration was determined by ROC curve.Results: Mean serum ferritin concentration in children with dengue shock (mean= 3628.8; SD= 1582.4) was higher than in children without dengue shock (mean= 717.8; SD= 695.8), with p<0.001. Therefore, there was a statistically significant asssociation between serum ferritin concentration and dengue shock .  The cut off point of serum ferritin concentration that could be used to show dengue shock with high sensitivity (0.92) and specificity (0.97) was 2304.5.Conclusion: High serum ferritin concentration is a predictor of dengue shock.Keywords: ferritin, dengue shock syndrome, childrenCorrespondence: Putri Evalda. Dr. Moewardi Hospital, Jl. Kolonel Sutarto No.132 Jebres, Surakarta, Central Java 57126. Email: dr. putri.evalda@gmail.com. Mobile: 081227970440Indonesian Journal of Medicine (2017), 2(3): 154-160https://doi.org/10.26911/theijmed.2017.02.03.02
Association between Left Ventricular Global Longitudinal Strain and Functional Capacity Measured with Six-Minutes Walk Test in Patients after Acute Myocardial Infarction. Wasyanto, Trisulo; Wulandari, Pipiet; Purwaningtyas, Niniek; Murti, Bhisma
Indonesian Journal of Medicine Vol 2, No 3 (2017)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: The ischemia resulting from critical coronary narrowing or total occlusion first affects the subendocardialmyofibers. Thus, abnormalities in longitudinal function can be detected before reductions in LVEF and reflects infarct size. The 6MWT provides information that may be a better index of the patients ability to perform daily activities. This study was to assess the relationship between left ventricular (LV) global longitudinal strain (GLS) and functional capacity measured with 6 minute walk test (6MWT) after AMI.Subjects and Method: This is a cross sectional study of patients with STEMI and NSTEMI, at Moewardi Hospital, Surakarta. Eligible patients underwent echocardiography global longitudinal 2D-STE that performed within 48 hour of admission and 6MWT pre- discharge or at the first follow-up visits (day 4-9). Patients were divided into 2 groups according to the LV GLS value, patients with substantial infarction (LV GLS > -13.8%) and non-substantial infarction (LV GLS < -13.8%).Results: There were 50 patients with 42 STEMI and 8 NSTEMI. Compared to patients in group LV GLS < -13.8% (n=18), patients in group LV GLS > -13.8% (n=32) were more likely to be older (57.6 y.ovs 55 y.o), less in functional capacity (10.17 1.3 ml/kg/min vs 11.04 0.98 ml/kg/min; p= 0.018) and less in 6 MWT distance (347.97 65.49 m vs392.39 49.44 m; p=0.016). Using ROC curves, the 6 MWT distance cutoff value of 375 m identified patients with LV GLS >-13.8%, sensitivity of 72.2% and specificity 65.6%, respectively with AUC= 0.70 (CI 95%; 0.559-0.852; p= 0.017). However, LV GLS >-13.8% and age >60 y.o remained the independent predictor in a multivariate logistic regression analysis to identify 6 MWT distance < 375 m in patients after AMI with GLS >-13.8%, (OR =7.967; CI 95%= 1.669-38.030; p=0.009) and age >60 y.o, (OR=10.898; CI95%= 2.201-53.971; p=0.003).Conclusions: In patients after AMI with substantial infarction (LV GLS >-13.8%) had less in functional capacity. The 6 MWT distance cutoff value of 375 m identified patients with LV GLS >-13.8% and could be used in rehabilitation program after AMI.Keywords: Acute Myocardial Infarction, LV Global longitudinal strain, functional capacity, 6 MWT.Correspondence:Trisulo Wasyanto. Department of Cardiology and Vascular Medicine, Faculty of Medicine, Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami No. 36 A, 57126, Surakarta, Central Java.Indonesian Journal of Medicine (2017), 2(3): 192-206https://doi.org/10.26911/theijmed.2017.02.03.07
The Effectiveness of Adding Probiotic to Antimicrobial Agents for the Treatment of Bacterial Vaginosis: A Systematic Review Darmayanti, Aquartuti Tri; Murti, Bhisma; Susilawati, Tri Nugraha
Indonesian Journal of Medicine Vol 2, No 3 (2017)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: Common antimicrobial regimens for treating bacterial vaginosis often cause recurrence and bacterial resistance. Previous studies have reported that a combination of antimicrobial and probiotic consisting of Lactobacillus spp. Is an effective treatment for recurrent bacterial vaginosis. Lactobacillus plays an important role in vaginal health by replacing the pathogenic colonies in vagina. This study aimed to determine the effectiveness of adding probiotic to antimicrobial therapeutic for the prevention of  bacterial vaginosis(BV) recurrence.Subjects and Method: A systematic review was conducted by searching the following databases: PubMed, Science Direct, Web of Science, Springer Link and the Cochrane. The review included randomized controlled trials (RCTs) conducted in primary hospitals and private clinics. The Amsel criteria and Nugent score were used for diagnosis appraisal of bacterial vaginosis. were included in this systematic review consisting of the two types of bacterial vaginosis treatment.  All pooled data analyses were based on random-effects models and intention to treat (ITT). Data were analyzed using Rev Man 5 software.Results: The review included 5 RCTs involving 692 women on reproductive age underwent treatment of BV for 5 days or more.The studies showed that combination of probiotic and antimicrobial treatment reduced the risk of bacterial vaginosis recurrence a half time compared to antimicrobial treatment alone(RR= 0.49; 95% CI= 0.17 to 1.44).Conclusion: Adding probiotic to antimicrobial regimens is more effective than antimicrobial regimens alone for treating bacterial vaginosis recurrence.Keywords: probiotic, antimicrobial, bacterial vaginosis recurrence, randomized controlled trialCorrespondence: Aquartuti Tri Darmayanti. Masters Program in Public Health, Sebelas Maret University, Jl. Ir. Sutami 36 A, Surakarta 57126, Central Java. Email: tutiaquar@gmail.com. Mobile: +6281329380114.Indonesian Journal of Medicine (2017), 2(3): 161-168https://doi.org/10.26911/theijmed.2017.02.03.03 

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