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Proceedings of the International Conference on Applied Science and Health
Published by Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)
ISSN : 25794434     EISSN : -     DOI : -
Core Subject : Health, Education,
Education Health Professions Medicine & Pharmacology Nursing Public Health
Proceedings of the International Conference on Applied Science and Health is a conference collection of technical papers freely accessible to scholars over the world. Articles featured vary areas of efforts to develop health and well-being for better society such as factors of illness, epidemiology, health promotion, health policy, nutrition, environmental health and safety, nursing and midwifery, and other sciences related to health development.
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Search results for , issue "No. 4 (2019)" : 269 Documents clear
THE EFFECT OF ORALLY ADMINISTERED CATFISH (Clarias gariepinus) SKIN AND MEAT ON EPITHELIALIZATION THICKNESS AND COLLAGEN DENSITY IN INCISION WOUND OF WISTAR RAT (Rattus norvegicus) Muhammad Irsyad Baihaqi; Muhammad Duddy Satrianugraha; Tiar M Pratamawati; Donny Nauphar
Proceedings of the International Conference on Applied Science and Health No. 4 (2019)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

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Background: Alternative medicine using animal is still rare whereas Indonesia have a lot of potential natural resources. Catfish is easily found animal in Indonesia and is common consumed as nutriment sources contains albumin, amino acid and fatty acids which plays an essential role of wound healing process. This study will determine effect of orally administered catfish (Clarias gariepinus) skin and meat on epithelialization thickness and collagen density in incision wound of white male rat (Rattus norvegicus).Methods: This experimental post-test only group design used 30 white male rat (Rattus norvegicus), that randomly divided into 4 tratment goup and one control group. The treatment group was given 12,5 mg/g W, 25 mg/g W, 37,5 mg/g W and 50 mg/g W dose of catfish (Clarias gariepinus) skin and meat flour, in the other hand the contol group were given aquades. Non-parametric analyses using Kruscall-Wallis and Mann Whitney test were used to compare epithelization thickness and collagen density.Result: The comparison results of epithelialization thickness between group C with TGI, C with TG2, C with TG3 and C with TG4 showed significant differences (p<0.05). TG4 was the thickest of all groups. Significant differences were also observed in collagen density result between C with TGI, C with TG2, C with TG3 and C with TG4 (p <0,05) TG4 showed the highest density of all groups.Conclusion: Catfish (Clarias gariepinus) skin and meat flour with 50 mg/200g W dose is effective for wound healing and increasing epithelial thickness and collagen density in Wistar rat (Rattus norvegicus) incision wounds.
CORRELATION BETWEEN ANXIETY LEVEL AND SELF DIRECTED LEARNING READINESS (SDLR) WITH STUDENT PEFORMANCE IN PROBLEM BASED LEARNING (PBL) Nita Safitri; Uswatun Khasanah; Ruri Eka Maryam Mulyaningsih
Proceedings of the International Conference on Applied Science and Health No. 4 (2019)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

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Background: The pattern of medical education in Indonesia has changed from teacher-centered learning to student-centered learning. This change has an impact on methods, learning activities, and learning achievements of medical students. Problem Based Learning (PBL) is one of the main learning methods used in the faculty of medicine. PBL is a learning method that requires students to play an active role and facilitate collaborative learning. Due to the change of learning method, new medical students experience a lot of stress from in doing Problem Based Learning such as anxiety and may affect their PBL results as can be evaluated using Self-Directed Learning Readiness (SDLR). There are very few studies found to date investigating this phenomenon.Aims: This research aims to see the correlation between anxiety level and SDLR with student’s performance participating in first-year PBL in the Musculoskeletal and Locomotory System block in the faculty of medicine Universitas Swadaya Gunung Jati Cirebon.Methods: This is a cross-sectional observational study with total sampling. The samples were recruited from 167 first-year 2018 intake students of the faculty of medicine Universitas Swadaya Gunung Jati. Zung Self Rating Anxiety Scale questionnaire is used to measure anxiety levels and the SDLR questionnaire is used to measure Self Directed Learning Readiness (SDLR).Results: The Spearman test showed a medium negative correlation value of -0.49 (p>0.05) for the level of anxiety. It means that there is no significant effect of anxiety on the PBL performance. In addition, it shows a weak positive correlation value of 0.196 (p <0.05) for SDLR (self-directed learning readiness) showing a significant influence on PBL performance.Conclusions: The level of anxiety does not significantly influence PBL performance while SDLR has a significant effect on PBL performance.
THE EFFECT OF SELF DIRECTED LEARNING READINESS (SDLR) AND LEARNING APPROACH TOWARD MEDICAL STUDENT ACHIEVEMENT Nurul Amaliah Lestari; Uswatun Hasanah; Ricardi Witjaksono Alibasjah
Proceedings of the International Conference on Applied Science and Health No. 4 (2019)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

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Background: Learning approach and Self Directed Learning Readiness (SDLR) are important factors that influence student learning achievement. The world of medical education has experienced a paradigm shift from Teacher-Centered Learning (TCL) to Student-Centered Learning (SCL) that is applied through the Problem Based Learning (PBL) methods that expected the student to have the ability to learn independently or what is called Self Directed Learning (SDL). This study aimed to analyzed the effect of SDLR and learning approach on medical student achievement.Methods : this study uses a cross-sectional design. The sample was students of the Faculty of Medicine, Swadaya Gunung Jati University, 2016, 2017 and 2018 as many as 181 people. The sampling technique uses stratified random sampling. Spearman test, chi-square test and linear regression test were used to analysed the effect of  the age, SLDR and learning approach on medical student achievementResults : The chi square test result in this study showed that age (P = 0.001; rs = 0.359), SDLR (P = 0.001; rs = 0.516) and the learning approach (P = 0.001; rs = 0.308) had a significant effect on medical students' learning achievement. However, there was no significant difference in the learning approach between 2016, 2017 and 2018 classes. The linear regression test results showed that SDLR was the most influential variable in the learning achievements of medical students.Conclusions : Self Directed Learning Readiness (SDLR) and learning approach could be the effective learning methods. SDLR as the most effective method to increase the learning achievements of medical student could be applied on many medical schools.
INHIBITORY OF SOURSOP LEAVES (Annona muricata L.) EXTRACT AGAINST Malassezia furfur GROWTH Rike Rizqilah; Dadan Ramadhan Apriyanto; Ruri Eka Maryam Mulyaningsih
Proceedings of the International Conference on Applied Science and Health No. 4 (2019)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

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Background: Malassezia furfur in certain conditions can turn into a pathological phase, from the yeast phase to the mycelia phase that attacks the stratum corneum. Malassezia furfur is one of the causes of Pityriasis versicolor. The prevalence of pityriasis versicolor in Indonesia is quite high at around 40-50%.  Several studies suggested that soursop leaves (Annona muricata L.)  contains active substances with anti-fungal properties.  This study aims to determine the inhibition of soursop leaves (Annona muricata L.) extract against the growth of Malassezia furfur.Methods: This study was an experimental study with Post-test Only Control Group Design.  Malassezia furfur fungi is used as subject in this study and ethanol extract of soursop leaves as a natural antifungal against Malassezia furfur. The concentrations of extract tested were 100%, 80%, 60%, 30%. Miconazole 2% was used as a positive control while DMSO 10% was used a negative one. The result of the study was analyzed by descriptive analysis which showed by increasing average diameter of antifungal.Results: The results showed that soursop leaves (Annona muricata L.)  extract had inhibitory effect on the growth of Malassezia furfur fungi  at 100% concentration of 2.50 mm, 80% at 1.50 mm, 60% at 0.47 mm, 30%  concentration at 0.25 mm and positive control of 14.50 mm. While as negative control, no inhibition zones were formed on SDA media.Conclusion: Soursop leaves (Annona muricata L.)  extract can inhibit the growth of Malassezia furfur, but the formed inhibition zone is weak. Further research is needed to found the best type of antifungal metabolites to maximize antifungal effects.
EFFECTIVENESS OF ORALLY USE TILAPIA (Oreochromis niloticus) ON WOUND LENGTH AND FIBROBLAST DENSITY ON INCISION WOUND OF WISTAR RAT (Rattus norvegicus) Sayyidah Vina Syauqia; A Fariz Malvi Zamzam Zein; Tiar M Pratamawati; Donny Nauphar
Proceedings of the International Conference on Applied Science and Health No. 4 (2019)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

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Background: The incidence of a wound in Indonesia has increased from 7.5 percent in 2007 to 8.2 percent in 2013 according to Riskesdas. Wound care that widely used is povidone-iodine, but in case, it has a toxic effect on healthy cells around the wound. The albumin, amino acids, and fatty acids in Tilapia  (Oreochromis niloticus) are the potential substances to accelerate the wound healing process. This study aims to investigate the efficacy of Tilapia (Oreochromis niloticus) on wound length and fibroblast density on the incision wound of Wistar rat (Rattus norvegicus).Methods: The study was conducted in the Food and Nutrition PAU Laboratory and Pathology Anatomy Laboratory of Universitas Gadjah Mada, Yogyakarta. This post-test only control group design experimental study used 30 male white rats that randomly divided into five groups, i.e. control group K, and treatment group P1, P2, P3 and P4 that were each given Tilapia with a dose of 12.5 mg/200gBW, 25 mg/200gBW, 37.5 mg/200gBW dan 50 mg/200gBW. The length of the wound was measured by a ruler each day. The rats were terminated on the 10th day to obtain wound tissue for H&E stained histopathological sections to observe fibroblast density. One Way ANOVA, Tamhane, Kruskal-Wallis and Mann Whitney tests were used to compare the wound length and fibroblasts density.Results: Incision wounds in this study showed the best wound healing on the 10th day. Based on the theory, on the 10th day, a proliferation and remodeling phase occurs. There is an effect of giving Tilapia (Oreochromis niloticus) orally at a different dose. Tilapia at dose 37.5mg/200gBW is more effective compared with the dose of 12.5mg/200gBW, 25mg/200gBW, and 50mg/200gBW to accelerate wound healing for wound length and fibroblast density in Wistar rat (Rattus norvegicus).Conclusion: Consuming Tilapia (Oreochromis niloticus) could be a new alternative for wound healing treatment. The antimicrobial ability of Tilapia should be analyzed.
EFFECTIVENESS OF ORALLY USE CATFISH (Clarias gariepinus) SKIN AND MEAT ON WOUND LENGTH AND FIBROBLAST DENSITY IN INCISION WOUND OF WISTAR RAT (Rattus norvegicus) Sri Utami Fauziah; Risnandya Primanagara; Tiar M Pratamawati; Donny Nauphar
Proceedings of the International Conference on Applied Science and Health No. 4 (2019)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

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Background: Treatment for wounds that are currently often given is use povidone-iodine. But, this antiseptics also kills fibroblast tissue which is useful for forming new tissue. One of the other ways to treatment for wounds is use catfish. The contents found in catfish (Clarias gariepinus) is albumin which is a globular protein that is useful in the formation of body tissues, such as postoperative wounds and burns. This study aims to determine the effect of skin and meat of catfish (Clarias gariepinus) on wound length and fibroblast density in incision wounds of Wistar rat (Rattus norvegicus).Methodology: This study is an experimental study with Post Test Only Control Group Design using Wistar rats which are divided into five groups. The control group (aquadest) and treatment groups 1, 2, 3 and 4 are given the skin and meat of catfish (Clarias gariepinus) orally at a dose of 12.5 mg / 200 g BW, 25 mg / 200 g BW, 37.5 mg / 200 g BW, and 50 mg / 200 g BW. After 10 days, the rats are killed to take the wound tissue for histological preparations to observe fibroblast density. Then, it is analyzed by ANOVA test or the alternative.Results: There is an effect of giving catfish skin and meat (Clarias gariepinus) orally at different dose. The administration of catfish skin and meat (Clarias gariepinus) at a dose of 37.5 mg / 200 g BW and 50 mg / 200 g BW is better than other doses assessed from wound length and fibroblast density in Wistar rat incision wounds (Rattus norvegicus).Conclusion: The use of catfish for wound healing can be applied. This method can reduce wound length and increase fibroblast density at certain doses.
INHIBITORY TEST OF DAYAK ONION (ELEUTHERINE BULBOSA MILL.) ESSENTIAL OIL TO THE GROWTH OF MALASSEZIA FURFUR Syahidatun Hayati; Amanah Amanah; Rose Indriyati
Proceedings of the International Conference on Applied Science and Health No. 4 (2019)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

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Background: Certain fungi are normal flora on human mucosa and skin, and they require lipids for growth. One of them is Malassezia furfur, which can develop into an opportunistic infection and will take a long time to treat. The fungus may cause pityriasis versicolor, which cause scaly and discoloration of the skin. It is estimated that 40-50% from population in the tropical country is infected. Dayak onion (Eleutherine bulbosa Mill.) essential oil have the potential to treat fungal infections. This research aims to see the inhibitory potential of dayak onion essential oil (Eleutherine bulbosa Mill.) in inhibiting the growth of Malassezia furfur.Methods: This is an experimental study with a post-test control group design. The samples grouped into 7 groups. The first five treatment (P1 to P5) was given dayak onion (Eleutherine bulbosa Mill.) essential oil with a concentration of 3.125%,6.25%, 12.5%, 25%, and 50%, P6 (positive control) was given ketoconazole, and P7 (negative control) was given 10% DMSO. The inhibitory effect is measured from the diameter of the inhibitory zone, then analyzed using Kruskal-Wallis and Mann-Whitney tests.Result: The result showed that average diameter on 50% concentration is 9.25mm, 25% concentration is 7.5mm, 12.5% concentration have diameter of 4.5mm, 6.25% concentration have diameter of 3mm, 3.125% concentration with diameter of 1.75mm, positive control group with diameter of 20mm, and negative control group with diameter 0mm.Conclusions: Essential oil of dayak onion (Eleutherine bulbosa Mill.) shows inhibition of the growth of Malassezia furfur. The smallest inhibition zone diameter was 1.75 mm with concentration of 3.125%. The largest inhibition zone at a concentration of 50% with diameter of 9.25 mm. This finding showed potential effects towards antifungi treatment.
THE INHIBITION TEST OF FLAVONOID AND TANNIN IN NONI FRUIT (Morinda citrifolia Linn) COMPARED TO CEFTRIAXONE TOWARDS Escherichia coli IN VITRO Tessa Swesty Islamia; Atik Sutisna; Hikmah Fitriani
Proceedings of the International Conference on Applied Science and Health No. 4 (2019)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

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Background: Escherichia coli is one of the causatives of infection agents. Noni fruit that contains the antibacterial ingredients was predicted as an alternative medicine to reduce the resistance of antibiotics. Noni fruit extract can inhibit the growth of Escherichia coli. The absence of research on the active substances contained in this fruit which plays a role in inhibiting the growth of Escherichia coli encourages the researcher to conduct this research.Methodology: The research was an experimental laboratory with post-test only control group design. The Escherichia coli grown on Mac conkey agar. Flavonoid and tannin in noni fruit (Morinda citrifolia Linn.) diluted with 3 concentrations, 50%, 70%, 100% and 2 control groups, positive control with ceftriaxone and negative control with Dimethylsulfoxide 10% (DMSO). The treatment group were incubated for 24 hours, then the inhibitory zone formed was measured in mm. Results: The Kruskall-Wallis test showed significant difference in all concentration. The results obtained from this research showed that the average of inhibition towards Escherichia coli on positive control (22.83 mm) had the largest inhibition zone among flavonoid 100% (18.83mm), flavonoid 70% (14.67 mm), flavonoid 50% (6 mm), tannin 100% (17.33 mm), tannin 70% (10.83 mm), tannin 50% (7.50 mm), and negative control (2 mm).Conclusion:  Flavonoid and tannin in noni fruit (Morinda citrifolia Linn) were effective for inhibiting the growth of Escherichia coli. The 100% concentration is the most effective concentration that can be promoted as an alternative medicine.
IMPACT OF OBESITY AND DIABETES MELLITUS TYPE II WITH INCIDENCE OF HYPERTENSION IN AGE 45-65 YEARS OLD Tiara Syamsa Noor Wildania; Shofa Nur Fauzah; Dini Sapardini Warsodoedi
Proceedings of the International Conference on Applied Science and Health No. 4 (2019)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

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Background: Hypertension is one of the main causes of mortality and morbidity in Indonesia. Hypertension is also the third biggest risk factor for early deaths. Several previous researches have shown that obesity and diabetes mellitus type II (DM type II) are the factors in the occurrence of hypertension. Previous research did not include the stage of obesity and DM type II, by this reason the research was aimed to analyze the correlation between the stage of obesity and stage of DM type II with hypertension.Methodology: This research used observational analytic with cross-sectional design. This study involved 161 patients who were selected by consecutive sampling method. The inclusion criteria of the sample were aged 45-60 years old, obese, and have been diagnosed of DM type II and hypertension in Waled Regional General Hospital.Results: The result revealed that stage of obesity and stage of DM type II were significantly associated with hypertension (p<001, p<01, respectively). Other variables that also significantly associated with hypertension were age and gender. Conclusion: There was the strong correlation between stage of obesity and hypertension. Public health policy maker may promote to prevent the obesity in order to decrease the incidence of hypertension.
THE CORRELATION OF EDUCATION AND SOCIAL ECONOMIC LEVELS WITH ANTIBIOTIC SELF-MEDICATION IN THE COMMUNITY OF CIREBON Tridaya Putri Handayani; Muhammad Duddy Satrianugraha; Witri Pratiwi; Ruri Eka Maryam Mulyaningsih
Proceedings of the International Conference on Applied Science and Health No. 4 (2019)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

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Background: People in developing countries, like Indonesia, often conduct self-medication. One of the most common drugs used in self-medication is antibiotics. Antibiotics should be used with caution since it can cause antibiotic resistance and possible unwanted side effects of the drug. There are several factors that influence self-medication behavior such as education and socio-economic levels. This research aims to find the correlation between education and social economic levels with antibiotic self-medication in the community of Cirebon.Method: This study was an analytical survey with cross-sectional method. This study was conducted from December 2018 to February 2019. A total of 300 respondents were recruited as samples using consecutive sampling technique. The respondents were recruited from 5 different pharmacies from each sub-district in Cirebon City and a validated questionnaire were used to obtain data. The collected data are analyzed using the Spearman correlation test.Results: The results of this study show that there was a significant but weak positive correlation of education level (r=0.224, p=0.001) and socio-economic (r=0.210, p=0.001) with self-medication using antibiotics. Conclusion: There is a significant positive correlation between education and socio-economic levels with antibiotic self-medication.

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