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INDONESIA
Global Health Management Journal
Published by Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)
ISSN : -     EISSN : 25809296     DOI : 10.35898/ghmj
Core Subject : Health, Education,
Education Health Professions Medicine & Pharmacology Nursing Public Health
GLOBAL HEALTH MANAGEMENT JOURNAL (GHMJ) focuses on health field with strong preference (but not limited) on public health in general, maternal and child health, nursing, midwifery, sexual and reproductive health, public health nutrition, environmental health, occupational health and safety, health promotion, health economics in South East Asia and other regions. Applied science in health also becomes one of our priority, especially in the field of health information and technology, innovation in health, and development of devices, medicines, vaccines, procedures and systems developed to solve a health problem and improve quality of lives.
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Articles 282 Documents
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Correlation between Duration of Antiretroviral Therapy and Glomerular Filtration Rate in People Living with HIV/AIDS: A Cross-sectional Study in Cirebon, West Java, Indonesia Ayudhipasha, Tiara Sekar; Herdwiyanti, Menik; Sedayu, Sedayu
GHMJ (Global Health Management Journal) Vol. 8 No. 1s (2025): Special Issues
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35898/ghmj-81s1182

Abstract

Background: West Java ranks the highest Province with Human Immunodeficiency Virus (HIV) case in 2023. An estimated 1.648 patients estimated receive antiretroviral therapy (ART). Kidney disease contributes mortality amongst people living with HIV/AIDS (PLWH). Tenofovir disoproxil fumarate (TDF)-based ART was associated as risk factor of kidney disorders, indicate by declining glomerular filtration rate (GFR). However, there is limited study whether kidney disease among PLWH were related to ART use in Indonesia. Aims: To determine correlation between duration of antiretroviral therapy and glomerular filtration rate (GFR) in people living with HIV/AIDS. Methods: This is an observational study with cross-sectional design. Eighty-nine HIV patients on antiretroviral therapy for at least three months with normal baseline GFR were studied. Estimated GFR calculated using the Cockcroft-Gault equation. Data obtained were analyzed with spearman correlation test. Results: Among 89 subjects, as many as 38 patients (42.7%) on therapy less than 12 months, 29 patients (32.6%) were on ART more than 24 months, and 22 patients (24.7%) 12-24 months. ART with normal kidney function were 62 patients (69.7%). Whereas 29.2% were mildly decrease GFR, and only 1.1% were mild to moderate decrease GFR. The analytical statistic showed a no significant between duration of antiretroviral therapy and GFR in PLWH with a p-value of 0.199 and Spearman’s r of 0.137. Conclusion: There was no significant correlation between duration of antiretroviral therapy and glomerular filtration rate in PLWH.
Effectivity Test of n-Hexane, Ethyl Acetate, and Butanol Fractions of Mango Peel (Mangifera indica L.) Gedong Gincu Variety on the Growth of Escherichia coli Siskanti, Alvina; Brajawikalpa, Rama Samara; Apriyanto, Dadan Ramadhan
GHMJ (Global Health Management Journal) Vol. 8 No. 1s (2025): Special Issues
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35898/ghmj-81s1186

Abstract

Background: Escherichia coli was the most common cause of diarrhea. Diarrhea reached a high prevalent in West Java. The cause of antibiotic resistance to Escherichia coli was noncompliance medication. Mango peel (Mangifera indica L.) of the Gedong Gincu variety had secondary metabolites compound which act as antibacterial that can be used as alternative medication. Aims: To analyze phytochemicals and determine effectiveness of n-hexane, ethyl acetate, and butanol fractions of mango peel Gedong Gincu variety in the growth of Escherichia coli. Methods: This study used laboratory true experimental research with post-test only control group design. This research consisted 14 groups, divided into 2 control groups, namely control (+) given ciprofloxacin and control (-) given 10% DMSO, and 12 treatment groups given n-hexane, ethyl acetate, and butanol fractions concentration of Gedong Gincu 6.25%v/v, 12.5% v/v, 25% v/v, and 50% v/v. The test used well diffusion method on Mueller-Hinton Agar media. Results: The secondary metabolites in the n-hexane fraction included alkaloids, steroids, and saponins, while ethyl acetate and butanol fractions contained flavonoids, phenols, alkaloids, triterpenoids, and tannins. The results of the oneway ANOVA test obtained p<0.001 which indicated n-hexane, ethyl acetate, and butanol fractions were significantly inhibit the growth of Escherichia coli with the greatest mean inhibitory zones of 6.86 mm, 12.08 mm, and 9.35 mm, respectively. Conclusion: The most effective fraction of mango peel (Mangifera indica L.) Gedong Gincu variety in inhibit the growth of Escherichia coli was ethyl acetate fraction at a 50% concentration (12.08 mm).
Reviewer Acknowledgements and Introduction of New Numbering Format: Special Edition from the Cirebon International Health Symposium - GHMJ (Global Health Management Journal), Volume 8, Number 1s, 2025 GHMJ (Global Health Management Journal)
GHMJ (Global Health Management Journal) Vol. 8 No. 1s (2025): Special Issues
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35898/ghmj-81s1217

Abstract

Starting from this edition, GHMJ (Global Health Management Journal) designates Special Editions with an “s” in the numbering (e.g., Vol. 8, No. 1s) to indicate their inclusion as a section within the ongoing issue, with all articles undergoing rigorous double-blind peer review to uphold the journal’s commitment to academic excellence. This issue of the Global Health Management Journal (Vol. 8, No. 1s, 2025) presents a diverse selection of articles reflecting the depth and breadth of current health research. From applied sciences, two studies examine the antimicrobial potential of mango peel extracts in inhibiting Staphylococcus aureus and Escherichia coli (‘Adawiyah et al., 2025; Siskanti et al., 2025), highlighting the value of natural resources in public health innovation. In the field of epidemiology and public health, important clinical insights are offered through studies on the relationship between antiretroviral therapy duration and kidney function in HIV/AIDS patients, as well as a retrospective review of psoriasis cases in Cirebon (Ayudhipasha et al., 2025; Putra et al., 2025). Medical education is addressed through an exploration of students' perceptions of ideal lecturer qualities in problem-based learning environments (Erlangga et al., 2025). Meanwhile, research in medical technology includes analyses of gene polymorphisms related to tuberculosis and diabetes, along with clinical evaluations of corneal curvature changes following cataract surgery (Oktaviyati et al., 2025; Putri et al., 2025; Nuruzzahrah et al., 2025). Finally, a study on mental health investigates the factors influencing the quality of life among patients with type 2 diabetes (Hidayat et al., 2025), emphasizing the ongoing need to consider psychosocial dimensions in chronic disease management. Together, these articles contribute to a growing body of evidence that supports more holistic and innovative approaches to global and community health.   Link to download: https://publications.inschool.id/index.php/ghmj/issue/view/CIHES01s   We extend our heartfelt appreciation to the reviewers who have played a crucial role in refining and enhancing these works.   Editor-in-chief Prof. Andrew John Macnab Managing Editors Doni Marisi Sinaga, M.Sc. Kukuh Madyaningrana, M.Biotech. Ph.D. Journal Managers Suyitno, M.PHM Maretalinia, M.A  Internal Reviewers from Faculty of Medicine, Universitas Swadaya Gunung Jati, Indonesia Donny Nauphar, M.Si.Med Ahmad Fariz Malvi Zamzam Zein, Sp.PD, FINASIM, MM, FACP Bambang Wibisono, MH Tiar M. Pratamawati, MM, M.Biomed Tissa Octavira Permatasari, M.MedEd Witri Pratiwi, M.Kes. Vivi Meidianawaty, M.MedEd  External Reviewers Supim Wongtongtair, Ph.D. (Srinakharinwirot University, Thailand) Eligible reviewers may be considered for future roles on our Editorial Board, and receive Exclusive Publishing Opportunity and the chance to publish Guest Editorial Papers at no cost. Simply register on our website and select the "Reviewer" option during sign-up.   Acceptance Rate                            : 30 % Days to First Editorial Decision : 28 days Days to accept                                : 27 days   Published: 02 May 2025.
Comparing Chest Radiograph Lesion Areas in Pulmonary Tuberculosis Patients with and without Diabetes Mellitus: A 2023 Study at Waled Hospital, Cirebon, Indonesia Fatihah, Hapsari Bunga; Latief, Muhammad Amar; Herdwiyanti, Menik
GHMJ (Global Health Management Journal) Vol. 8 No. 2 (2025)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35898/ghmj-821161

Abstract

Background: The Global Tuberculosis Report emphasizes a significant number of TB cases, and Indonesia is the second country in Southeast Asia with the most TB cases. Prevalence of TB increases along with the increase of Diabetes Mellitus (DM) prevalence, which both are known to have a negative impact on each other. Clinical symptoms in TB with DM differ from those in TB without DM. However, whether there is any difference in radiology examinations is unknown. This can be a consideration for determining patient therapy based on differences in the chest radiographs. Aims: To determine the Lesion Area Difference on Chest Radiographs of Pulmonary Tuberculosis Patients with and without Diabetes Mellitus at Waled Hospital in 2023. Methods: There were 96 data points based on the first taken chest radiograph from both inpatient and outpatient data, which were obtained from medical records in 2023 at Waled Hospital, Cirebon. Statistical analysis was performed using the Chi-Squared comparative test in this observational study with a cross-sectional design. Results: There were 69 tuberculosis (TB) patients without diabetes mellitus (DM) and 27 TB patients with DM. Overall, patients had minimal lesions (14.6%), moderate lesions (26.0%), and far-advanced lesions (59.4%). The Chi-Square analysis from these samples showed a p-value of 0.870. Conclusion: There is no difference in lesion area on chest x-rays in pulmonary tuberculosis patients with or without diabetes mellitus. Further research is expected to include the type of TB and history of treatment for either TB or DM.
The Effectiveness of the Combination of Bay Leaf Extract (Syzygium polyanthum) and Celery Leaf Extract (Apium graveolans L.) on Lowering Blood Sugar Level in Wistar Rats (Rattus norvegicus) Laorenz, Diva Erita; Naldi, Yandri; Oktavrisa, Friska
GHMJ (Global Health Management Journal) Vol. 8 No. 2 (2025)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35898/ghmj-821174

Abstract

Background: Diabetes mellitus is a metabolic disorder marked by high blood glucose levels. According to the WHO, approximately 422 million people worldwide were living with diabetes in 2023, with 1.5 million diabetes-related deaths reported annually. Based on the RISKESDAS data, the prevalence of diabetes in Indonesia was 8.5% in 2018, affecting approximately 20.4 million individuals, and the increase is closely linked to rising obesity rates. Diabetes treatment involves both medication and lifestyle changes. Indonesia has many herbal plants, such as bay and celery leaves, which contain bioactive compounds like flavonoids, alkaloids, saponins, and tannins believed to have antihyperglycemic properties. Aims: This study aimed to evaluate the effectiveness of the combination of bay leaf extract (Syzygium polyanthum) and celery leaf extracts (Apium graveolans L.) against lowering blood sugar levels in white male Wistar rats (Rattus norvegicus). Methods: This research is an experimental study using a pre- and post-test control group design. A total of 25 male Wistar white rats (Rattus norvegicus) were induced with alloxan and then divided into five groups: Group 1 (G1) as the negative control; Group 2 (G2) as the positive control, treated with the drug glibenclamide; Group 3 (G3) received bay leaf extract at a dose of 300 mg/kgBW; Group 4 (G4) received celery leaf extract at a dose of 300 mg/kgBW; and Group 5 (G5) received a combination of bay leaf and celery leaf extracts at a dose of 300 mg/kgBW. The post-test was conducted twice : Post-test 1 was carried out 60th minutes after treatment, and Post-test 2 was conducted 120th minutes after treatment. Blood glucose levels were measured using a glucometer. Results: At 60th minutes post-treatment, blood sugar levels decreased by 40 mg/dL in G1, 100 mg/dL in G2, 44 mg/dL in G3, 57.4 mg/dL in G4, and 70.8 mg/dL in G5. At 120th minutes, the decreases were 45 mg/dL (G1), 104.6 mg/dL (G2), 49.2 mg/dL (G3), 62 mg/dL (G4), and 77.6 mg/dL (G5). The Post Hoc LSD test showed a statistically significant average decrease of 5 mg/dL between post-test 1 and post-test 2 (p < 0.001). Conclusion: The combination of bay leaf extract and celery leaf extract at a dose of 300 mg/kgBW is most effective in reducing blood glucose levels in hyperglycemic Wistar rats.
Inhibition Test of Cassava Leaves (Manihot Esculenta Crantz) Flavonoid Nicotiflorin on Replication of Dengue Virus Serotype 1 in Vitro Yulianti, Selsa; Apriyanto, Dadan Ramadhan; Brajawikalpa, Rama Samara; Dewi, Beti Ernawati
GHMJ (Global Health Management Journal) Vol. 8 No. 2 (2025)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35898/ghmj-821192

Abstract

Background:  Dengue fever is a disease caused by the bite of Aedes aegypti mosquitoes infected with the dengue virus. Dengue virus infection can lead to hemorrhagic fever and even death. Currently, treatment for dengue infection is supportive, as there are no commercially available antiviral drugs. Nicotiflorin, a compound found in cassava leaves (Manihot esculenta Crantz), has shown potential as an antiviral agent against dengue. Aims: This study aimed to determine the inhibitory effect of the flavonoid nicotiflorin, derived from cassava (Manihot esculenta Crantz) leaves, as an antiviral agent against dengue virus serotype 1 (DENV-1) in vitro. Methods: A post-test-only control group design was utilized in this experimental research, comprising one control group alongside thirteen treatment groups. For the cytotoxicity assessment, the treatment groups were exposed to seven varying concentrations (1.25 µg/mL, 2.5 µg/mL, 5 µg/mL, 10 µg/mL, 20 µg/mL, 40 µg/mL, and 80 µg/mL), while six different concentration levels (1.5 µg/mL, 3.125 µg/mL, 6.25 µg/mL, 12.5 µg/mL, 25 µg/mL, and 50 µg/mL) were employed in the inhibition assay. The control group received 0.2% DMSO as a negative control. Antiviral inhibition was assessed using the Focus Forming Unit (FFU) Assay, while cytotoxicity was evaluated using the Microtiter Tetrazolium Assay (MTT Assay). Statistical analyses included the Shapiro-Wilk test for normality, the Kruskal-Wallis test for hypothesis testing, and post-hoc analysis to assess significant differences among treatment groups. Results: The CC₅₀ and IC₅₀ values of nicotiflorin from cassava leaves were determined to be 19.24 μg/mL and 0.9550 μg/mL, respectively, yielding a Selectivity Index (SI) of 20.14. These findings indicate that the flavonoid nicotiflorin from cassava leaves exhibits selective antiviral activity against DENV-1 replication. Statistical analysis revealed a non-normal data distribution (P < 0.05), a significant difference among groups based on the Kruskal-Wallis test (P < 0.05), and no statistically significant differences among specific concentrations in the post-hoc test. Conclusion: Nicotiflorin from cassava leaf (Manihot esculenta Crantz) has inhibitory activity on the replication of dengue virus serotype 1 strain in vitro.
Comparison of Healing Time in Closed Fractures of the Tibial Diaphysis and Tibial-Fibula after ORIF Plate and Screw at Waled Regional Public Hospital, Indonesia Sakinah, Dede Nurlaela; Putro, Widiyatmiko Arifin; Debyanti, Merliana
GHMJ (Global Health Management Journal) Vol. 8 No. 2 (2025)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35898/ghmj-821200

Abstract

Background: Fractures are projected to become the fourth leading cause of death by 2030. A fracture is a discontinuity in the bone that is often accompanied by damage to the surrounding tissues. The healing process of fractures is influenced by various factors, the greater the damage to the bone and surrounding tissues, the longer the healing time. In cases of tibia and fibula fractures, the most commonly used surgical procedure in Indonesia is Open Reduction and Internal Fixation (ORIF) using Plates and Screw. Aims: To compare of healing time in closed fractures of the tibial diaphysis and tibial-fibula after ORIF Plate and Screw at Waled regional public hospital. Methods: This research uses a cross sectional design. A total of 77 samples were obtained using total sampling. Statistical tests use Mann Whitney. Results: There were 37 patients with closed fractures of the tibia diaphysis and 40 patients with closed fractures of the tibia-fibula diaphysis. The healing time for closed tibial diaphyseal fractures was ≤ 24 weeks in 12 patients (32.4%), while > 24 weeks was 25 patients (67.6%). In patients with closed fractures of the tibia-fibula diaphysis within ≤ 24 weeks and > 24 weeks, the number was the same, namely 20 patients (50.0%). In the Mann-Whitney test, a significance value of 0.032 (p<0.05) was obtained, indicating a significant difference in the healing time between closed fractures of the tibial diaphysis and tibia-fibula after ORIF Plate and Screw at Waled Regional Hospital, with an average healing of 44.69 weeks for closed fractures of the tibial diaphysis, whereas for fractures closed tibia-fibula diaphysis 33.74 weeks.   Conclusion: The average healing time for closed tibial diaphyseal fractures is longer than for tibia-fibula.
Rethinking Educational Research Involving Students with Disabilities Muzite, Precious; Gasa, Velisiwe
GHMJ (Global Health Management Journal) Vol. 8 No. 2 (2025)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35898/ghmj-821212

Abstract

Background: This paper investigates the decolonisation of educational research concerning students with disabilities. Aims: The primary aim was to validate and interpret these students' lived experiences, challenging established dominant epistemologies in disability studies. Methods: A radical near-experience methodology, which emphasises participant-driven storytelling within their contextual realities, was employed as a qualitative research design. Twenty youths, aged 16 to 24, with either physical or learning disabilities, enrolled at five TVET Colleges, or Technical and Vocational Education and Training Colleges, in Gauteng, South Africa, engaged in storytelling exercises tailored to their abilities. Results: The storytelling exercises revealed key themes, including identity affirmation, systemic challenges, and agency. Findings indicate that conventional disability research often marginalises students' voices, perpetuating stereotypes and failing to enact meaningful policy changes. For instance, participants expressed feelings of empowerment and recognition through their narratives. Conclusion: This research holds significant implications for policymakers, highlighting the need for inclusive education studies that genuinely reflect the experiences of students with disabilities. Disability advocates can utilise these narratives to promote redefined identities and rights. Scholars can incorporate decolonial methodologies into their work, fostering a nuanced understanding of disability relevant to the global South. Additionally, practitioners in human services can leverage these insights to design supportive programs that encourage self-advocacy and positive identity formation. By prioritising the voices and experiences of individuals with disabilities, this study underscores the transformative potential of inclusive educational practices.
Pregnancy Outcomes among Adolescents and Young Adults with Diabetes in Kumasi, Ghana Ameyaw, Emmanuel; Asafo-Agyei, Serwah Bonsu; Hammond, Charles Kumi; Nguah, Samuel Blay; Damalie, Francis Jojo Kwadzo; Senaya, Charles Mawunyo; Adutwum, Laila Matogah
GHMJ (Global Health Management Journal) Vol. 8 No. 2 (2025)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35898/ghmj-821213

Abstract

Background: Pregnancy in patients with diabetes is known to be associated with complications. Improving glycaemic control can improve pregnancy outcomes. Aims: This study assessed pregnancy outcomes among adolescents and young women with diabetes at Paediatric and Adolescent Diabetes Clinic, Komfo Anokye Teaching Hospital, Kumasi, Ghana. Methods: A clinical review involving eighteen children and young women with diabetes who became pregnant during follow-up care at Paediatric and Adolescent Diabetes Clinic in Ghana. Girls and young women suspected to be pregnant were referred to antenatal clinic for confirmation. Multidisciplinary care including comprehensive antenatal care was given to each participant throughout the pregnancy. Questionnaire was used to gather demographic and clinical information of participants including pregnancy outcomes.  Results: A total of eighteen adolescents and young women got pregnant and were included in the study. They were attending school when they got pregnant, 55.6% were in Senior High School, 33.3% were in Junior High School and 11.1% were in Teacher Training College. The mean age at pregnancy was 18.39 years (SD 2.97). Two pregnancies ended in abortion while 16 resulted in 18 live births (14 singleton and 2 twin deliveries). All deliveries were supervised, 56.3% delivered via cesarean section. Two births were preterm, occurring at 30 and 32 weeks of gestation. Neonatal outcomes were generally favorable: all babies were clinically well, 55.6% had 5-minute APGAR (Appearance, Pulse, Grimace, Activity, and Respiration) score between 8 and 10, while 44.4% had 5-minute APGAR score between 6 and 7. Only one infant (5.6%) had a congenital malformation. One baby died at one month due to septicemia. Conclusion: Structured multidisciplinary interventions led to positive pregnancy outcomes among young females with diabetes in Ghana.
Strengthening Laboratory Capabilities in Improving HIV/AIDS and Other Diseases Support in Zimbabwe Mayavo, Crossman
GHMJ (Global Health Management Journal) Vol. 8 No. 2 (2025)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35898/ghmj-82992

Abstract

Background: Laboratory services are always overlooked by the governments when it comes to funding, and they are mostly left behind in terms of newer testing technologies, however, in Zimbabwe, there has been a tremendous improvement in laboratory support through the partners and donors. Aims: The objective of the study was to review the progress made in strengthening laboratory capabilities in improving HIV/AIDS and other disease support in Zimbabwe. Methods: This study adopted a qualitative research method based on secondary data collected from laboratory documentation, including websites such as SADCAS. The study focused mainly on laboratories scattered around Zimbabwe, on the improvements made in support of HIV care in Zimbabwe. Results: The results show that there has been a great improvement in terms of laboratory performance and management through support from various donors interested in HIV/AIDS, TB and Malaria. Furthermore, the results show that there are currently 13 public health laboratories accredited to SADCAS, several improvements in employee support, and new technologies are being employed throughout the Zimbabwean laboratories for both HIV and TB care. Additionally, the laboratory information system is functional and now helps to send laboratory results to clinics and patients for patient management by all the clinics and hospitals. Conclusion: However, concerns regarding reliance on and the sustainability of these partnerships remain a challenge if they sever ties with the laboratory services, as the funding from the government is not adequate to support the laboratory’s full independence. As for the policy makers, they can help to improve the funding gaps to enable sustainability in the long run so that the gains acquired will not go to waste if the donors and partners decide otherwise, as is happening with USAID and PEPFAR funding. 

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