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Erina Yatmasari
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Oceana Biomedicina Journal
Published by Universitas Hang Tuah
ISSN : -     EISSN : 26140519     DOI : https://doi.org/10.30649/obj.v5i1.67
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Dentistry Medicine & Pharmacology Nursing Public Health
Oceana Biomedicina Journal is an open access journal of health and medicine.Specifically, the journal focuses on marine medicine, hyperbaric medicine and health, medicine on ships, harbor health, maritime and coastal health, medicolegal studies related to ships, ports and districts, maritime/coastal communities and fishermen, epidemiological aspects of diseases, disabilities and disorders that occur on ships and affect boat workers, ports and maritime zones, coastal areas, fishermen communities and their families, including pharmacological and non-pharmacological prevention and treatment management policies; and miscellanous.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 110 Documents
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IDENTIFIKASI DAN PENETAPAN KADAR SENYAWA SAPONIN EKSTRAK ETANOL BUNGA SENGGANI (MELASTOMA MALABATHRICUM L) METODE GRAVIMETRI Dewi, Berliana Rosita; Noviyanty, Yuska; Hepiyansori, Hepiyansori
Oceana Biomedicina Journal Vol 3, No 1 (2020): Oceana Biomedicina Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (372.537 KB) | DOI: 10.30649/obj.v3i1.46

Abstract

Traditional medicine is an ancestral cultural heritage derived from natural materials and to this day continue to be used by the general public. One of the plants that can be used as a traditional medicine is a plant Senggani (Melastoma malabathricum L). The purpose of this study was to determine the saponins contained from flower extracts Senggani (Melastoma malabathricum L) and percent saponin levels of Senggani flower extract (Melastoma malabathricum L).Extraction is done by maceration using ethanol 96% for 5 days. Extraction obtained is then concentrated by means of a rotary evaporator. The results were qualitative identification of the foam test and color test and quantitative assay with gravimetric method.Based on research conducted Senggani ethanol extracts of flowers (Melastoma malabathricum L) contains saponins types of triterpenoids seen from the ring in maroon and obtained the average level of interest saponin Senggani (Melastoma malabathricum L) is 11.46%.Keywords: Flowers Senggani, saponin, Gravimetry
STUDI FORMULASI SABUN CUCI DARI MINYAK JELANTAH DENGAN PENAMBAHAN AIR ASAM SUNTI Adriani, Azmalina; Rinaldi, Rinaldi; Hardiana, Hardiana; Suci, Suci; Mustafa, Irfan
Oceana Biomedicina Journal Vol 3, No 1 (2020): Oceana Biomedicina Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (462.001 KB) | DOI: 10.30649/obj.v3i1.38

Abstract

Soap is a cleaning agent made from oil. Coconut oil that has been used is usually discarded as waste (minyak jelantah), with the additionof syringe acid water. Sunti acid water is one of the spices that contains quite high acidic compounds. The purpose of this study was to determine the characteristics of soaps containing Sunti acid water. This research is experimental to formulate laundry soap containing Sunti acid water, with used cooking oil. Soap formulation with Sunti acid water concentration 1.25% (F1), 1.50% (F2) and 1.75% (F3). The formula was evaluated with organoleptic parameters, moisture content, pH, homogeneity, high foam and clean power of soap. The results showed that soap (F1, F2, F3) was solid, brown in color and distinctively smelled of lemon, and the water content was 20.34%; 14.21% and 14.8%, pH ranges from 8-10, not homogeneous, foam height 48-78 cm and can be as a cleaner. So it can be concluded that Sunti acid water and used cooking oil can be formulated in the form of soap and formula 3 is a good formula.            Keywords: Sunti acid water, used cooking oil, soap
ETHANOLIC EXTRACT OITMENT OF THE GRAPTOPHYLUM PICTUM L GRIFF LEAVES AS ANALGESIC AGENT TO MALE WHITE RAT Rikomah, Setya Enti; Fitri, Ninsi
Oceana Biomedicina Journal Vol 3, No 1 (2020): Oceana Biomedicina Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (435.505 KB) | DOI: 10.30649/obj.v3i1.45

Abstract

Graptophyllum pictum L Griff Leaves in the community are used as medicinal ingredients, one of which is for analgesics. Black pudding leaves contain secondary metabolite compounds that act as suspected analgesics, namely flavonoids. The ethanolic extract of black pudding leaves has been formulated into cream and ointment preparations. The purpose of this study was to determine the effectiveness of analgesic preparations of black pudding leaves (Graptophyllum pictum L. Griff) ethanol extract in white male mice. The effectiveness of analgesics was tested using the hotplate method. The test animals used were 25 white male mice which were divided into 5 groups: negative control (F0), positive control (Ichtiol® ointment), and black pudding leaf F1 (10%), F2 (15%) ethanol extract treatment group, and F3 (20%). Observation of stretching of mice was done after the feet of mice were induced and immediately given treatment. Observation of analgesic percentage in each mouse was carried out every 5 minutes for 60 minutes. The data obtained were processed and analyzed using one-way ANOVA and Duncan test with a 95% confidence level. One-way ANOVA test results showed that there were significant differences between treatment groups (0.003 <0.05). The results of the average percentage of analgesic effectiveness of formula 2 have a good effect that is equal to 77.969%. Duncan's test results showed that the group that gave the best analgesic effectiveness was formula 2 (15%) comparable to positive control.Keywords: Graptophyllum pictum,  Analgesics, ointment, Hotplate.
PENGARUH TERAPI OKSIGEN HIPERBARIK 2,4 ATA 3X30 MENIT 5 SESI TERHADAP KADAR TESTOSTERON PADA TIKUS MODEL SINDROMA OVARIUM POLIKISTIK DENGAN RESISTENSI INSULIN Sudiono, Fajar; Susanto, Lunardhi; Kurnia, Wachjudi
Oceana Biomedicina Journal Vol 3, No 1 (2020): Oceana Biomedicina Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/obj.v3i1.25

Abstract

ABSTRAKLatar Belakang:Sindroma ovarium polikistik (SOPK) adalah suatu kelainan endokrin yang mempunyai spektrum gambaran yang luas dan paling sering timbul pada wanita usia reproduktif. Faktor yang mendasari terjadinya SOPK adalah androgen yang berlebih, resistensi insulin, dan gangguan dinamika gonadotropin. Androgen yang berlebih menyebabkan ketidak seimbangan LH dan FSH. Terapi oksigen hiperbarik menurut teori dapat meningkatkan sensitivitas jaringan terhadap insulin. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh terapi okssigen hiperbarik 2,4 ATA 3x30 menit selama 5 sesi terhadap kadar testosterone pada tikus model Sindroma Ovarium Polikistik dengan resistensi insulin.Metode:Penelitian ini merupakan penelitian eksperimental sejati dengan post test only control group design. Besar sampel yang digunakan sebanyak 12 ekor yang terbagi menjadi 2 kelompok. Variabel bebas pada penelitian adalah terapi oksigen hiperbarik, variabel terikatnya yaitu kadar testosteron pada sampel darah tikus putih dan variabel controlnya suhu ruang dan pakan standart serta variabel kendalinya injeksi androgen, jenis dan spesifikasi hewan coba, ukuran kandang dan perawatan hewan. Analisis data penelitian ini diolah menggunakan uji Uji Mann Whitney U.Hasil:Hasil data menggunakan Uji Mann Whitney U menunjukkan tidak ada perbedaan antara Kadar testosteron kelompok hewan coba yang diberi injeksi androgen dengan kelompok hewan coba yang diberi injeksi androgen dan terapi oksigen hiperbarik.Kesimpulan:Pemberian terapi oksigen hiperbarik tidak berpengaruh terhadap Kadar testosterone pada kelompok tikus putih (Rattus Norvegicus) model Sindrom ovarium polikistik dengan resistensi insulin. Kata kunci: Terapi oksigen hiperbarik, Kadar testoteron, Sindroma ovarium polikistik, Resistensi insulin
SEORANG PENDERITA SLE DENGAN EMBOLI PARU AKUT DAN HIPERTENSI PULMONAL (STUDI KASUS) Andisari, Hendrata Erry; Kambayana, Gede; Suega, Ketut
Oceana Biomedicina Journal Vol 3, No 1 (2020): Oceana Biomedicina Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (662.233 KB) | DOI: 10.30649/obj.v3i1.31

Abstract

Kondisi Pulmonary embolism (PE) merupakan bagian dari spektrum penyakit yang disebut Venous thromboembolism (VTE).  Seorang pasien dengan keluhan utama batuk yang mengeluarkan dahak berwarna keputihan datang ke RSUP Sanglah, Bali untuk mendapatkan terapi. Riwayat sebelumnya, pasien pernah dirawat inap di RSUP Sanglah tersebut.Saat ini diagnosis akhir pasien ini: SLE on treatment dengan moderate pulmonary hipertension dan suspek emboli paru, suspek pneumonia (HCAP) dengan severe sepsis dan syok sepsis, asidosis metabolik, observasi transaminitis ec reaktif dan hiponatremia kronik asimptomatik hipoosmoler euvolemic cb SIADH. Selanjutnya dilakukan tindakan terapi dan evaluasi terhadap terapi yang diberikan. Kata kunci: SLE, emboli paru akut, hipertensi, studi kasus
Effects of Morning’s Prayer Routines in The Congregation on Random Blood Sugar Levels of Elderly at Al Wahyu Mosque Rungkut Surabaya Indri Ngesti Rahayu; Lani Diana; R. Varidianto Yudo Tjahjono
Oceana Biomedicina Journal Vol 4 No 2 (2021): Oceana Biomedicina Journal Volume 4 Issue (No) 2
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/obj.v4i2.12

Abstract

Background: Increased health problems in the elderly occur because of the aging process that causes many changes in their body. One of the changes istheincrease in blood glucose more than normal and at risk of diabetes mellitus. Morning prayer can be a religious coping and regular physical activity that lowers blood sugar levels. Objective: to analyze the effect of the morning prayer routines in the congregation on random blood sugar levels of the elderly at Al-Wahyu Mosque Rungkut Surabaya. Method:This study was an observational analytic study with a cross-sectional design using 30 respondents. The group studied was the congregation of the morning prayers of the Al Wahyu MosqueRungkut Surabaya which was over 45-year-old which undergoes random blood sugar levels measurement. Results:The Independent t-testmethodshowedthat the value of signification was 0,000 (p<0,05) which means that there is the influence of the morning prayer’s routines in the congregation on random blood sugar levels of the elderly at Al-Wahyu Mosque Rungkut Surabaya. Conclusion:Elderly people who routinely carry out the morning prayer routines in the congregation have lower blood sugar levels than elderly people who are not routine.
UJI POTENSI ANTI KANKER EKTRAK ETANOL BIJI KEBIUL (Caesalpinia bonduc (L) Roxb) DENGAN METODE BRINE SHRIMP LETHALITY TEST (BSLT) Densi Selpia Sopianti; Aina Fathkil; Yesa Christine Sanuki
Oceana Biomedicina Journal Vol 4 No 2 (2021): Oceana Biomedicina Journal Volume 4 Issue (No) 2
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/obj.v4i2.13

Abstract

Cancer becomes a global health problem which is estimated to continue to increase in number. The prevalence of cancer in Indonesia is 1.4% or around 347,792 people. Cancer treatment is currently carried out with chemotherapy, radiotherapy, and surgery. At present many active compounds from herbal plants are believed to be one of the alternatives used by the community as an anticancer, shown by several studies and the availability of active compounds from a single herbal plant isolated from plants as anticancer easily found by the community and have minimal side effects. One of the potential plants in Bengkulu is Kebiul (Caesalpiniabonduc (L.) Roxb) which, according to the Bengkulu community, is used for various diseases. The purpose of this study is that the researchers wanted to test the potential of the active compound of whistle seeds (Caesalpiniabonduc (L.) Roxb) with the Brine Shrimp Lethality Test method. The stages of this research were by making dried simplicia from whistle seeds then extracted with 96% ethanol and evaporated on a rotary evaporator until thick ethanol extract was obtained. The extract was tested using the BSLT Method, calculated the number of larval deaths and measured LD50. The results of the probit value equation analysis showed the LC50 value of the ethanol extract of whistle seeds was 11,1943μg/mL, this shows that the ethanol extract of the whistle seeds was very toxic which was indicated by LC50 values ​​<30 μg / mL.
AKTIVITAS ANTIBAKTERI EKSTRAK KAYU SIWAK (Salvadora persica) TERHADAP BAKTERI Staphylococcus epidermidis Nugroho Eko W B
Oceana Biomedicina Journal Vol 4 No 2 (2021): Oceana Biomedicina Journal Volume 4 Issue (No) 2
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/obj.v4i2.14

Abstract

Background:Siwak is a plant that grows in the Arabian Peninsula which is used to clean teeth. Siwak has antibacterial properties because it contains flavonoids and alkaloids. This study aims to prove whether the extract of siwak stem powder can be used to inhibit the growth of Staphylococcus epidermidis bacteria Methods: In this study, using the Only Post Test Control Group Design method, namely pure experimental treatment and measuring the dependent variable. This study used 24 samples which were divided into four replications and six treatments. The study used extracts of siwak stems at concentrations of 25%, 50%, 75% and 100% and used clindamycin as a positive control and aquadest as a negative control. Research Results: The results showed that the average inhibition zones of siwak stem extract on the growth of Staphylococcus epidermidis from concentrations of 25%, 50%, 75%, and 100% were 0 mm, 0 mm, 10.01 mm and 14.65 mm. Conclusion: At a concentration of 75% ethanol extract of siwak stems, it was able to exert an inhibitory effect on the growth of Staphylococcus epidermidis bacteria but was still unable to match the inhibitory power of clindamycin.
KEGAWATAN PADA REAKSI TRANSFUSI Hendrata Erry Andisari
Oceana Biomedicina Journal Vol 4 No 2 (2021): Oceana Biomedicina Journal Volume 4 Issue (No) 2
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/obj.v4i2.15

Abstract

Reaksi tranfusi dapat dibedakan antara yang dimediasi imun dan tidak dimediasi imun. Keduanya dapat terjadi segera maupun reaksinya bisa lambat. Reaksi tranfusi yang dimediasi imun biasanya terjadi akibat aloantibodi setelah terekspose dengan antigen asing seperti kehamilan, tranfusi atau transplantasi. Kontaminan leukosit dapat menyebabkan aloimmunisasi, transmisi dari penyakit menular, TRALI dan imunomodulasi. Dengan pelatihan yang tepat untuk mengenali tanda dan gejala reaksi transfusi, komplikasi yang muncul akibat transfusi dapat dihindari. Diketahuinya penyebab sebagian besar reaksi transfusi bersifat klerikal sehingga dilakukan usaha untuk mencegah kesalahan klerikal sepanjang proses transfusi. Eksklusi kontaminan leukosit dari darah dan produk darah dapat mengurangi insiden FNHTR, aloimunisasi, dan imunosupresi. Filtrasi darah dan produk darah sebelum penyimpanan dapat menjadi cara yang efektif untuk mengatasi masalah tersebut terkait kontaminasi leukosit. Jika protokol transfusi yang tepat serta prosedur operasional standar diikuti, maka insiden reaksi transfusi dapat sangat menurun.
MIKROPENIS PADA ANAK DENGAN BERAT BADAN NORMAL Peter Gunawan Tandean
Oceana Biomedicina Journal Vol 4 No 2 (2021): Oceana Biomedicina Journal Volume 4 Issue (No) 2
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/obj.v4i2.16

Abstract

Latar Belakang: Mikropenis adalah diagnosis medis yang seringkali salah untuk ditegakkan. Mikropenis dapat terjadi sebagai kelainan tunggal dengan sendirinya maupun sebagai salah satu gejala dari suatu penyakit. Tujuan: Laporan kasus ini diperlukan untuk menegakkan diagnosis penyebab mikropenis pada anak laki-laki dengan berat badan normal. Metode: Metode yang digunakan adalah dengan melakukan penegakkan diagnosis secara lege artists berdasarkan referensi ilmiah mutakhir. Hasil: Laporan kasus ini memberikan hasil mengenai penegakkan diagnosis penyebab mikropenis pada anak laki-laki dengan berat badan normal. Kesimpulan: Kesimpulan dari laporan kasus ini adalah didapatkannya penyebab dari mikropenis dari anak laki-laki dengan berat badan normal.

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