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Contact Name
Amin Fatoni
Contact Email
aminfatoni@unsoed.ac.id
Phone
-
Journal Mail Official
j.molekul@gmail.com
Editorial Address
Jl. Dr. Soeparno No.61 Karangwangkal, Purwokerto, Jawa Tengah 53
Location
Kab. banyumas,
Jawa tengah
INDONESIA
Molekul: Jurnal Ilmiah Kimia
ISSN : 19079761     EISSN : 25030310     DOI : -
MOLEKUL is a peer-reviewed journal of chemistry published by the Department of Chemistry, Faculty of Mathematics and Natural Sciences, Jenderal Soedirman University, Indonesia. Publishing frequency 2 issues per year, on May and November. This Journal encompasses all branches of chemistry and its sub-disciplines including Pharmaceutical, Biological activities of Synthetic Drugs, Environmental Chemistry, Biochemistry, Polymer Chemistry, Petroleum Chemistry, and Agricultural Chemistry.
Arjuna Subject : -
Articles 14 Documents
Search results for , issue "Vol 12, No 1 (2017)" : 14 Documents clear
The Effect of Iron Ion to the Removal of Nickel Ion From Electroplating Wastewater Using Double Chamber Electrodeposition Cell (DCEC) Reactor Djaenudin Djaenudin; Dani Permana
Molekul Vol 12, No 1 (2017)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (715.636 KB) | DOI: 10.20884/1.jm.2017.12.1.232

Abstract

Modern society demands industrial technology advances to produce products that have high durability and long utilization lives. Materials made from ferrous metal become a solution to meet these industry needs. Ferrous metal is corrosive and it requires more care to support the performance. Electroplating or metal coating applied to iron or nickel solves this problem. In the production process, the usage of nickel is only 30%-40% and the remaining 60-70% is wasted through effluent. Nickel is a toxic heavy metal that can cause cancer. The purpose of this study is to evaluate the effect of iron concentration on nickel metal removal in electroplating wastewater using an insulated electrolytic reactor double chamber electrodeposition cell (DCEC). The result of this study shows that any ratio variation of iron concentration to nickel gives varying impacts on nickel removal efficiency, electric current efficiency, and specific energy. On the fourth variation, the iron ratio of 1.29% removed 83.1% nickel (the highest removal efficiency) at the cost of 20.687 kWh / kg specific energy. The number is extremely high for energy needs. On the other hand, the variation of iron ratio of 1.73% consumpting only 15.067 kWh / kg, the lowest specific energy needs, resulted in the lowest removal efficiency of 63.6%.
Subchronic Toxicity of Methanol Extract From Erythrina Variegata (Leguminosae) Leaves on Male Wistar Rats (Rattus Norvegicus) Tati Herlina; Madihah Madihah; Deden Deni; Suseno Amien
Molekul Vol 12, No 1 (2017)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (576.948 KB) | DOI: 10.20884/1.jm.2017.12.1.349

Abstract

Erythrina variegata is a herbal plant commonly used in Indonesia traditional medicine for treatment malaria disease. Acute toxicity test results showed that the methanol extract of E. variegata leaves categorized as practically nontoxic. In this study, we investigated sub chronic toxicity of the extract on male Wistar rats and the procedure based on guidelines of OECD 408 (1998) and EPA OPPTS 870.3100 (1998) for 90 constitutive days. The rats are classified into four dose groups were 0 (control), 250, 500, and 1000 mg/kg body weight with each group consist of five test animals. The results do not show toxic signs either behavior or body weight changed. Hematological analysis and clinical blood chemistry revealed slightly changes but were within the normal limits, except for BUN and SGPT values. Histopathological examination showed an increased damage of liver and kidney cells in form hydropic degeneration, fatty degeneration, as well as necrosis along with increased of extract doses that significantly different with control (p<0.05). However, the damage is reversible and was assumed had not has relations with the treatment. Thus, orally administration of E. variegata extract by dosage 250, 500, and 1000 mg/kg BW did not cause subchronic toxicity on male Wistar rats.
The Hydrophobicity and the Antibacterial Activity of Polyester Modified With Silver Nanoparticle and Hexadecyltrimethoxysilane Eli Rohaeti; Anna Rakhmawati
Molekul Vol 12, No 1 (2017)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (750.974 KB) | DOI: 10.20884/1.jm.2017.12.1.295

Abstract

The objective of this research were to study hydrophobicity and antibacterial activity of polyester fibers before and after modification by using silver nanoparticles as antibacterial agent and hexadecyltrimethoxysilane (HDTMS) as self cleaning agent. The research was conducted in stages, chemical preparation of silver nanoparticles, deposit of silver nanoparticles on polyester fiber, modification of polyester fiber through the addition HDTMS, and characterization. Modification of polyester fibers with silver nanoparticles and HDTMS was conducted through dipping method, followed by curing. Characterization was conducted by testing the contact angle and antibacterial activity against Staphylococcus aureus ATCC 25923 and Escherichia coli ATCC 35218. Silver nanoparticles has been prepared by adding sodium citrate and polyvinylalcohol as stabilizer. The addition of silver nanoparticles decreased hydrophobicity of polyester fibers without and with modification. Modification with HDTMS increased hydrophobicity of polyester fibers. Modification with silver nanoparticles and HDTMS increased antibacterial activity of polyester fabrics. Statistic analysis showed that there were significant differences in the antibacterial activity of polyester fibers against Staphylococcus aureus ATCC 25923 and Escherichia coli ATCC 35218
Cytotoxic Steroids from The Stem Bark of Chisocheton cumingianus (Meliaceae) Dewa Gede Katja; Kindi Farabi; Nurlelasari Nurlelasari; Desi Harneti; Euis Julaeha; Ace Tatang Hidayat; Tri Mayanti; Rani Maharani; Unang Supratman; Khalijah Awang
Molekul Vol 12, No 1 (2017)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (373.58 KB) | DOI: 10.20884/1.jm.2017.12.1.257

Abstract

Three cytotoxic steroids, stigmasterol (1), stigmast-5-en-3b-ol (2) and b-sitosterol-3-O-acetate (3) were isolated from the stem bark of Chisocheton cumingianus. The chemical structures of those compounds were identified based on spectroscopic data and by comparison with those data previously reported. All of the compounds isolated were evaluated for their cytotoxic effects against P-388 murine leukemia cells in vitro. Compounds 1-3 showed cytotoxicity activity against P-388 murine leukemia cells with IC50values of 12.4, 60.8, and ˃ 100 mg/mL, respectively.

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