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INDONESIA
ISM (Intisari Sains Medis) : Jurnal Kedokteran
Published by Universitas Udayana
ISSN : 25033638     EISSN : -     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology
Intisari Sains Medis is published by Medical Scientific Community, Indonesia. Intisari Sains Medis is an international, multidisciplinary, peer-reviewed, open access journal accepts papers for publication in all aspects of Science Digest, Medical Research Development, Research Medical Field and Theory. We also publish cases from third world country, that is considered very rare and special cases.
Arjuna Subject : -
Articles 1,063 Documents
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Korelasi negatif kuat kadar prolaktin plasma yang rendah terhadap derajat keparahan melasma Angela Sandi Tagaroi Rahasia; Anak Agung Gde Putra Wiraguna; Luh Made Mas Rusyati
Intisari Sains Medis Vol. 10 No. 1 (2019): (Available online 1 April 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (608.557 KB) | DOI: 10.15562/ism.v10i1.309

Abstract

Background: Melasma is a chronic cutaneous hypermelanosis in areas exposed to sunlight. Hormonal factors are known to influence melanogenesis processes such as prolactin as a neuroendocrine modulator in skin epithelial growth and immune system. This study aims to prove the inverse relationship between plasma prolactin levels and the severity of melasma.Methods: A cross-sectional study was carried out on 59 patients in the skin and genital olyclinic at Sanglah Hospital in Denpasar involving 46 subjects of melasma and 13 subjects who were not melasma who met the inclusion and exclusion criteria. Plasma prolactin levels were assessed by the Chemiluminescent microparticle immunoassay (CMIA) method. Data analysis was performed using SPSS ver. 23 software with a P-value <0.05 was considered statistically significant.Results: Plasma prolactin levels in patients with melasma were significantly lower than non-melasma patients (p <0.05). Patients with moderate and severe degrees of melasma had significantly lower plasma prolactin levels compared with mild degree of melasma (p <0.05). Low plasma prolactin levels can increase the likelihood of melasma by 4.79 times (PR 4.79; 95% CI = 0.94-24.27; p <0.05). Low plasma prolactin levels were significantly strong negative correlated with melasma severity (r = -0.820; p <0.05).Conclusion: There is a strong negative correlation of low plasma prolactin levels with the severity of melasma in patients with skin disorders at Sanglah General Hospital
Intranasal premedication: special consideration in children I Wayan Eka Arnawa
Intisari Sains Medis Vol. 9 No. 3 (2018): (Available online: 1 December 2018)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (485.286 KB) | DOI: 10.15562/ism.v9i3.310

Abstract

Introduction: Surgery in special population such as children may lead to emotional and physical stress. Premedication use may be beneficial in children anesthesia to reduce emotional stress and anxiety but still to be used in special consideration with adjustment dose. Intranasal premedication provides a broad effect of sedation and anti-anxiety and maybe produce a beneficial effect in child anesthesia.Aim: This study aimed to provide an overview regarding intranasal drugs and also intranasal premedication function in childrenConclusion: The intranasal application of pre-anesthetic drugs is the preferred route of administration and is an effective way to provide sedatives to children.
The characteristic of neonatal hyperbilirubinemia before and after phototherapy at Sanglah Hospital, Denpasar, Bali in 2017 Wayan Sulaksmana Sandhi Parwata; Putu Junara Putra; Made Kardana; Wayan Dharma Artana; Made Sukmawati
Intisari Sains Medis Vol. 10 No. 2 (2019): (Available online: 1 August 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (223.866 KB) | DOI: 10.15562/ism.v10i2.312

Abstract

Background: Hyperbilirubinemia is the most clinical problem in newborn babies.  Hyperbilirubinemia occurs 60% in aterm babies and 80% in premature babies. This study aims to know the incidence of hyperbilirubinemia, characteristics of hyperbilirubinemia and effect of phototherapies to bilirubin levels.Methods: A cross-sectional retrospective study was conducted using medical records among 94 neonates with hyperbilirubinemia who treated with phototherapies at Sanglah hospital during 2017. Data regarding gender, gestational weeks, type of delivery, size for gestational age, the onset of hyperbilirubinemia, etiology, birth weight, maternal gravid status, and bilirubin levels were collected and analyzed using SPSS version 20 software descriptively.Results: From 94 neonatal hyperbilirubinemia that meet the inclusion criteria, 51 (54.3%)  males and 43 (45.7%) females based on gender. Mean gestational ages were 36.35±2.921 weeks. The major etiology of neonatal hyperbilirubinemia were breastfeeding jaundice 33 (25.8%), Prematurity 23 (18.7%), ABO incompatibility 13 (10.6%), Breast milk jaundice 11 (8.9%), gastrointestinal malformation 6 (4.9%), G6PD deficiency 5 (4.1%), and sepsis 3 (2.4%). The mean total bilirubin prior to phototherapy was 15.6±4.11 mg/dL whereas the indirect bilirubin was 14.56± 3.55 mg/dL. The duration of phototherapy in this study was 2.8±0.65 days.Conclusions: The incidence of neonatal hyperbilirubinemia during 2017 at Sanglah Hospital were predominantly caused by breastfeeding jaundice, prematurity, and ABO incompatibility. There were decreased bilirubin levels following phototherapies.
Perbedaan pemberian cairan isotonis dan hipotonis terhadap osmolalitas plasma pada penderita gangguan intrakranial akut di RSUP Sanglah, Denpasar, Bali Wayan Sulaksmana Sandhi Parwata; I Nyoman Budi Hartawan; I Gusti Ngurah Suwarba; Ida Bagus Suparyatha; Dyah Kanya Wati
Intisari Sains Medis Vol. 10 No. 1 (2019): (Available online 1 April 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (237.617 KB) | DOI: 10.15562/ism.v10i1.313

Abstract

Background: Acute intracranial disturbance can lead to increased occurrence of cardiovascular activity that will lead to a decrease of sodium reabsorption in the kidney. The proper selection of liquid on acute intracranial disorders can help reduce damage to brain tissue. This study aims to determine differences in plasma osmolality levels in patients with acute intracranial disorders who get isotonic or hypotonic fluid.Methods: A cross-sectional observational study was carried out among 60 patients aged 1 month-12 years who experienced acute intracranial disturbance in Sanglah General Hospital during 2017. The difference in plasma osmolality in each group was tested using Mann-Whitney due to the data were not normally distributed. There was a significant difference in osmolality levels in the group receiving isotonic fluid compared with hypotonic (p <0.001)Results: Males were predominant in the isotonic group (66.7%) and hypotonic (70%). Good nutritional status was found in both groups (90%; 83.33%). Encephalitis is the most common cause of acute intracranial disturbance, namely 14 (46.67%) cases of istononic groups and 12 (40%) cases of hypotonic groups. The median value (IQR) of plasma and sodium osmolality levels that obtained isotonic fluid showed a difference in values of 139(6) mEq/L and 287(20) mOsm/kg H2O in isotonic and 132 (7) mEq/ L and 273(16) mOsm/kg H2O in hypotonic. There was a significant difference in osmolality levels in the group receiving isotonic fluid compared to hypotonic (p<0.001)Conclusion: There are differences in levels of osmolality in patients with acute intracranial disorders who get isotonic fluid compared to groups that get hypotonic fluid.
Gambaran umum berbagai faktor keterlambatan pemberian nutrisi enteral pada pasien anak di Ruang Rawat Intensif Anak, RSUP Sanglah, Denpasar, Bali Ni Luh Sri Apsari; I Gusti Lanang Sidiartha; I Nyoman Budi Hartawan; Dyah Kanya Wati; Ida Bagus Gede Suparyatha
Intisari Sains Medis Vol. 10 No. 2 (2019): (Available online: 1 August 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (230.525 KB) | DOI: 10.15562/ism.v10i2.314

Abstract

Background: Enteral nutrition is the primary choice in pediatric patients who do not experience gastrointestinal disorders. Many factors inhibit the achievement of enteral nutrition in pediatric patients treated in intensive care. This study aims to determine the overview of various factors that may result in delays enteral nutrition administration in critically ill pediatric patientsMethods: An observational cross-sectional analytic study was carried out on secondary data of medical records among children who were treated in pediatric intensive care unit at Sanglah Hospital throughout 2016. Delay in enteral nutrition was assessed if there was enteral nutrition administration more than 2x24 hours since first admission. Factors assessed include gender, age, PELOD, diagnosis, invasive breathing aids, impaired motility, gastrointestinal bleeding, and hemodynamic instability. Data were analyzed using the SPSS version 20 software program whereas P value <0.05 was considered statistically significant.Results: From the 115 samples, there were 69 (60%) males and 46 (40%) females. About 50 samples (43,5%) experienced delayed enteral nutrition. Significant variables related to the delay in enteral nutrition after multivariate analysis were gastrointestinal motility disorders (p = 0,004, OR 9,082, 95% IK 2,827 – 29,171), and gastrointestinal bleeding (p = 0,0001; OR 14,317; IK 95 % 4,087 – 50,155).Conclusion Intestinal motility disorders and gastrointestinal bleeding are known as a contributing factor in the delay of enteral nutrition administration in PICU Sanglah Hospital, Denpasar, Bali.
Prevalensi infeksi soil transmitted helmith di Sekolah Dasar Negeri 1 Padangbulia Kecamatan Sukasada Kabupaten Buleleng, Bali-Indonesia Ni Putu Akopita Devi; I Made Sudarmaja; Kadek Swastika
Intisari Sains Medis Vol. 9 No. 3 (2018): (Available online: 1 December 2018)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (497.285 KB) | DOI: 10.15562/ism.v9i3.315

Abstract

Latar Belakang: Pada perkembangan global yang sudah modern ternyata masih banyak kejadian infeksi cacing pada anak-anak. Infeksi cacing ini juga berhubungan dengan status gizi anak-anak. Beberapa penelitian juga menyebutkan bahwa kebersihan diri pada anak-anak sangat berpengaruh dengan terjadi nya infeksi cacing seperti perilaku mencuci tangan, memotong kuku, kebersihan yang dikonsumsi, dan masih banyak lagi. Penelitian ini bertujuan untuk mengetahui prevalensi infeksi cacing, dan juga hubungan status gizi serta kebersihan diri pada anak sekolah dasar di SD Negeri 1 Padangbulia Kecamatan Sukasada Kabupaten Buleleng.Metode: Penelitian ini adalah penelitian deskriptif dengan studi total sampling dengan jumlah sampel 127 orang. Instrumen yang digunakan adalah kuesioner tentang kebersihan diri untuk mendapatkan katagori baik dan buruk, serta perhitungan berat badan dan tinggi badan menggunakan timbangan dan microtoise.Hasil: Dari 127 siswa, 20 siswa dikatagorikan kurus, 84 siswa dikatagorikan normal dan 11 orang dikatagorikan gemuk. Hampir sebagian besar kebersihan siswa sangat baik dengan rajin mencuci tangan, memotong kuku, makan makananan yang bersih, dan bermain dengan menggunakan alas kaki. Selain itu ditemukan 6 kasus dengan infeksi askariasis dan trikuriasis.Simpulan: Pada penelitian ini kebersihan pada siswa sekolah dasar sudah baik begitu pula status gizinya. Kedepannya diharapkan adanya penelitian lebih lanjut dengan design penelitian yang lebih baik tentang infeksi cacing, status gizi, dan kebersihan diri. Prevalensi cacingan pada penelitian ini adalah 0,04%.
Trigger finger management, comparison of conservative and surgical treatment approach in hospital decision making: a case report Anak Agung Ngurah Bayu Putra; Anak Agung Ngurah Ronny Kesuma
Intisari Sains Medis Vol. 10 No. 1 (2019): (Available online 1 April 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (361.983 KB) | DOI: 10.15562/ism.v10i1.316

Abstract

Introduction: Trigger fingers are conditioned as the inability of the digit to move flex and extend caused by inflammation in the proximal edge of the flexor tendon pulley, such condition will have an impact on daily living activity and functional activity of person. Aim of this report is to give an overview regarding trigger finger clinical presentation with approach management in clinical setting.Case Presentation: A 39-old male come to the policlinic with complaint stiffness in right middle finger, on physical examination finding the middle finger on the right hand is locking in flexed position, tenderness palpation over the A1 pulley.Conclusion: Trigger finger is condition inability the digit can’t move smoothly in flexed and extended. The management of trigger finger is based on Quinnell classification, after grading the treatment divided with conservative treatment or surgical treatment and both of treatment have success rate and complication rate.
Proporsi kejadian depresi pada lansia di wilayah kerja Puskesmas Karangasem I, Bali-Indonesia I Gst. Agung Yudha Prasetya; Ni Luh Putu Aryastuti
Intisari Sains Medis Vol. 10 No. 1 (2019): (Available online 1 April 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (247.861 KB) | DOI: 10.15562/ism.v10i1.317

Abstract

Introduction: Indonesia entered an ageing population era because the geriatrics percentage was above 7%. In 2015, Karangasem I Community Health Centre served 3015 geriatrics. The escalation of chronic disease visits at geriatric polyclinic indicated an increasing geriatrics health burden. Depression was one of the most frequent psychiatric problems on geriatrics. In the preliminary survey were found that 3, out of 10 geriatrics had depressive mood. This study aimed to found the proportion of depression among geriatrics and the possible factors associated at Karangasem I Community Health Centre Region.Method: This was a descriptive cross sectional study. Pertima Village was randomly chosen and 73 samples were obtained using accidental sampling technique. Geriatric Depression Scale-15 was used to determine depression.Result: The result showed the proportion of depression was 67,1% with 57,1% was mild depression. The tendency of depression was found on several factors such as being female (67,4%), age category ≥80 years old (88,9%), unemployed (69,4%), uneducated (83,3%), widow/widower/single status (69,4%), living alone (76,9%), being the head of household (72,7%), having chronic disease (68%), and never participate on posyandu (100%).Conclusion: Prevalence of geriatric depression are quite high, sosial participation is needed to assist in preventing depression on geriatrics. Therefore, role of Community Health Centre was necessary on planning and holding more program and activities for elderly. Besides, it was necessary in improving the medical personnel skill on psychiatry for early detection and prompt treatment of depression among elderly.
Perbandingan efektivitas teknik modifikasi dan konvensional pada operasi open pyelolithotomy batu staghorn I Gede Hendra Sucipta; Anak Agung Gde Oka; I Gede Raka Widiana
Intisari Sains Medis Vol. 10 No. 1 (2019): (Available online 1 April 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (249.328 KB) | DOI: 10.15562/ism.v10i1.318

Abstract

Background: Open pyelolithotomy for staghorn stone patient management has a high stone-free rate. The disadvantages of open pyelolithotomy include aesthetics and postoperative complications, so a breakthrough to reduce these complications is needed, which can be achieved by doing modified open pyelolithotomy.Objective: To compare the modified and conventional open pyelolithotomy techniques according to the duration of operation, the volume of surgical bleeding, pain, and post-operative drop in hemoglobin (Hb).Method: A quasi-experimental study with twenty-two samples of staghorn stone patients was collected from October 2016 to October 2017. Parametric tests were used as data were normally distributed and homogeneous. The independent t-test was used to compare each measured parameter according to the type of operation. Analysis of covariance (ANCOVA) was used to control the variables of age, gender, and body mass index (BMI).Result: The modified technique had a shorter operating duration than the conventional method (p < .05). The volume of surgical bleeding in the modified technique was lower compared to the conventional technique (p < .05). Pain scores in the modified technique were lower than the conventional technique (p <  .05). The drop in Hb levels in the modified technique was lower than the conventional technique (p < .05). Analysis using ANCOVA found that the type of operation has a direct effect on the duration of operation, volume of surgical bleeding, and post-operative pain.Conclusion: The modified open pyelolithotomy technique was more effective than the conventional open pyelolithotomy technique based on the duration of operation, the volume of surgical bleeding, and post-operative pain scale. In this study, it was found that the drop in Hb levels was not directly affected by the type of surgery.
Hubungan prematuritas dengan kejadian sepsis neonatorum yang dirawat di ruang perinatologi dan neonatal intensive care unit (NICU) RSUD Wangaya kota Denpasar I Gusti Amanda Jaya; I Wayan Bikin Suryawan; Putu Pramitha Rahayu
Intisari Sains Medis Vol. 10 No. 1 (2019): (Available online 1 April 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (216.025 KB) | DOI: 10.15562/ism.v10i1.319

Abstract

Background: Premature neonates have an immature immune system due to the lack of IgG antibodies. These antibodies do not cross the placenta from mother to baby at last trimester that can increase the risk of neonatal sepsis. This study aims to determine the relationship between prematurity and the incidence of neonatal sepsis at Perinatology Ward and NICU Wangaya General Hospitals, Denpasar.Methods: This research used analytical observation with cross sectional study design from January-April 2018. The samples involved are 50 neonates, admitted at Perinatology Ward and NICU Wangaya Hospital and fulfilled the inclusion and exclusion criteria. Samples were obtained by using consecutive sampling method and using secondary data from the medical recordResult: 23 samples (46%) premature and 27 samples (54%) were not premature, out of 50 samples as many as 20 samples with neonatal sepsis. From the results of hypothesis testing using the chi-square test, the p-value is 0.005, and the prevalence risk was 2.73.Conclusion: Prematurity is significantly related with the incident of neonatal sepsis at Perinatology Ward and NICU Wangaya Hospital, Denpasar City.

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