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INDONESIA
ISM (Intisari Sains Medis) : Jurnal Kedokteran
Published by Universitas Udayana
ISSN : 25033638     EISSN : -     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology
Intisari Sains Medis is published by Medical Scientific Community, Indonesia. Intisari Sains Medis is an international, multidisciplinary, peer-reviewed, open access journal accepts papers for publication in all aspects of Science Digest, Medical Research Development, Research Medical Field and Theory. We also publish cases from third world country, that is considered very rare and special cases.
Arjuna Subject : -
Articles 1,063 Documents
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Awareness of breast cancer risk factors and practice of breast self - examination among female students in Medical Faculty, Udayana University, Bali Shalini Kalithasan; Gede Eka Rusdi Antara
Intisari Sains Medis Vol. 10 No. 1 (2019): (Available online 1 April 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (205.522 KB) | DOI: 10.15562/ism.v10i1.320

Abstract

Background: Breast cancer patients generally have low rates of survival rates due to late-stage diagnosis as patients usually present at and late stage because of lack of awareness and ignorance of risk factors.Methods: The objectives of this study are to evaluate the knowledge of risk factor for breast cancers and the practice of breast self-examination among female students in medical faculty at Udayana University. A cross sectional study conducted over a period of one month. 100 female students were volunteered to take part in the survey. The data were analyzed descriptively.Results: A half of the students have moderate knowledge of breast cancer risk factors, and the majority of the students do not practice breast self-examination monthly.Conclusions: It was suggested to students have more concern about relevant education programs that are having around them. 
Pneumotoraks spontan primer berulang pada wanita hamil dengan hiperemesis gravidarum: laporan kasus Ni Putu Ayu Widiasari; Ni Luh Putu Eka Arisanti; Ida Bagus Ngurah Rai
Intisari Sains Medis Vol. 10 No. 1 (2019): (Available online 1 April 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1040.03 KB) | DOI: 10.15562/ism.v10i1.321

Abstract

Background: Spontaneous pneumothorax is a rare case during pregnancy. However, the condition of Hyperemesis Gravidarum during pregnancy is one of the risk factors for recurrent primary spontaneous pneumothorax.Case Description: A 28-year-old woman with G5P3013 gestational age 12-13 weeks with Hyperemesis Gravidarum had complaints of tightness and recurrent acute pleuritic chest pain. After a clinical and supporting examination using ultrasound, patients were diagnosed with recurrent primary spontaneous pneumothorax, and observational and symptomatic treatments were performed. The rupture of the bleb or the subpleura bulla is thought to be a pathological mechanism. Patients given birth vaginally without complications and complete resolution of the pneumothorax occurred.Conclusion: Recurrent pneumothorax in pregnant women with a history of hyperemesis gravidarum is rare. Observational and symptomatic treatment is the initial treatment that can be done.
Hubungan antara derajat dehidrasi dengan penurunan berat badan pada anak diare usia 1 sampai 5 tahun di ruangan kaswari dan poliklinik anak RSUD Wangaya kota Denpasar William Grandinata Soeseno; I Wayan Bikin Suryawan; Kadek Suarca
Intisari Sains Medis Vol. 10 No. 1 (2019): (Available online 1 April 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (207.992 KB) | DOI: 10.15562/ism.v10i1.322

Abstract

Background: Children with diarrhea occurrences at ages 1 to 5 years had a prevalence of 16,7% in developing countries. Children suffer from diarrhea more than 12 times per year, and this is also the cause of death by 15 – 34 % of all causes of death. Most of the death from diarrhea due to dehydration begin with dehydration symptoms and decreased body weight. Diarrheal disease cannot be underestimated. Comprehensive, holistic and rational handling is required.Methods: This study was observational analytic research with cross sectional study design. This study aimed to investigate the correlation between the degree of dehydration with a weight loss of diarrhea children aged 1 - 5 year. The sample is 55 diarrhea children aged 1 to 5 years with dehydration and without dehydration in Kaswari and Clinic pediatric at Wangaya Hospital Denpasar from May until August 2018. The data was analyzed by Chi-Square testResult: 24 of 30 children aged 1 to 5 years with mild-moderate dehydration diarrhea lose weight (80%), while the other 6 did not lose weight (20%) with p-value = 0,001.Conclusion: There is a relation between degrees of dehydration with weight loss in diarrhea children at Kaswari and clinic pediatric room Wangaya Hospital, Denpasar.
Status kesehatan ginggiva pengguna alat ortodontik cekat pada mahasiswa Fakultas Kedokteran Universitas Udayana, Denpasar, Bali Ni Made Yeni Septianing Diah; Putu Ika Anggaraeni; Louise Cinthia Hutomo
Intisari Sains Medis Vol. 10 No. 1 (2019): (Available online 1 April 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (224.097 KB) | DOI: 10.15562/ism.v10i1.323

Abstract

Background: Maintaining the cleanliness of the oral cavity in users of fixed orthodontic devices is a difficult thing to do, due to the form of a complicated fixed orthodontic device. Therefore this initial study aimed to determine the health status of university students of Faculty of Medicine, Udayana University, using fixed orthodontic devicesMethod: An observational cross-sectional study was conducted among 67 students using fixed orthodontic devices at the Medical Faculty of Udayana University. Several questions regarding the use of fixed orthodontic devices and oral examination using the Modified Gingival Index (MGI) were carried out. Descriptive data is displayed in percentage using SPSS version 25 software.Result: Of the 67 samples, the majority were female (79.1%), 21 years old (32.83%), more than 2 years used fixed orthodontic devices (41.8%), and had a control schedule on follow up (67,16%). The healthy status of gingiva with fixed orthodontic appliance users was found as many as 52 people (77.6%) and had ginggival health status on the mild inflammation criteria of 15 people (22.4%). The healthy status of gingiva with fixed orthodontic appliance users was found as many as 52 people (77.6%) and had ginggival health status on the mild inflammation criteria of 15 people (22.4%). Based on gingival status, it was found that more healthy criteria were found in women (59.70%), age 21 years (23.9%), use of orthodontic devices more than 2 years (31.34%), and regularity of controls (50.75%).Conclusion: Most of the students of the Medical Faculty of Udayana University as users of fixed orthodontic devices have good health status.
Persentase remaja pengguna rokok pada klien klinik napza di Rumah Sakit Umum Pusat Sanglah Denpasar Ade Purnamasari; Ni Ketut Sri Diniari; Anak Ayu Sri Wahyuni
Intisari Sains Medis Vol. 10 No. 1 (2019): (Available online 1 April 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (205.461 KB) | DOI: 10.15562/ism.v10i1.325

Abstract

Introduction: Smoking is a major cause of preventable death worldwide, and is a major risk factor for six of the eight leading causes of death, namely ischemic heart disease, cerebrovascular disease, lower respiratory infections, chronic pulmonary obstructive disease, tuberculosis and lung cancer. This study aims to determine the percentage of cigarette use, the characteristics of age for the first time smoking, and the percentage of use of cigarettes, alcohol, and other substances in PTRM Sandat clients Sanglah Hospital.Method: This study was conducted at PTRM Sandat Sanglah Hospital in August to October 2015 using a descriptive cross-sectional design.Results: The results of this study showed 100% of respondents smoked at a young age with 76% of respondents having a daily smoking status. The data obtained showed that the majority of smoking clients in the age of 13-15 years were 56% and 42% smoked at 16-19 years old. Judging from alcohol consumption, all study respondents consumed alcohol and 74% of respondents consumed marijuana. Of the total respondents, 60% consumed benzodiazepine and 62% of respondents took amphetamines. As many as 66% of respondents took halucinogen drugs and were responsive who consumed opioids by 36%.Conclusion: Percentage of cigarette use in PTRM Sandat clients Sanglah Hospital one hundred percent positive using cigarettes with most having daily smoking status and all starting smoking in their teens. Smoking on PTRM Sandat clients at Sanglah General Hospital when teenagers become gateways for other drug use.
Deteksi molekuler mecA pada isolat klinis methycilin resistant Staphylococcus aureus (MRSA) dengan menggunakan teknik polymerase chain reaction (PCR) di RSUP Sanglah Denpasar Putu Ayu Utami Prajawaty; Ni Nengah Dwi Fatmawati
Intisari Sains Medis Vol. 9 No. 3 (2018): (Available online: 1 December 2018)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (526.958 KB) | DOI: 10.15562/ism.v9i3.327

Abstract

Introduction: MRSA is a bacteria that has experienced resistance to antibiotics, which generally has a function in killing Staphylococcus aureus, for the example Methicillin. In the worldwide MRSA prevalence is increasing, while the factors that cause the increase of the prevalence of MRSA is increasing the length of time of treatment in hospital, the misuse of antibiotics and poor infection control in the hospital. Laboratory tests were good and accurate were needed to identify MRSA as soon as possible so as to enable to conduct appropriate infection control. The aim of this study was to determine that the PCR can be used to confirm MRSA isolates.Methods: This study used a cross sectional design on all isolated Staphylococcus aureus isolates from all clinical specimens examined at the Laboratory of Clinical Microbiology, Sanglah General Hospital, Denpasar from 2011 until 2012.Results: A total of 38 samples were used, 32 (84.2%) positive S. aureus confirmed mecA genes using PCR technique. However, there are still 15.8% who are misidentified, where the possibility of the bacteria is not MRSA or the retrieval technique from the bacteria itself when conducting the research.Conclusion: MecA gene examination using PCR method is an examination that can be used to detect MRSA bacteria. 
Peran sitokin dalam kerusakan saraf pada penyakit kusta: Tinjuan Pustaka I Gusti Nyoman Darmaputra; Putu Ayu Dewita Ganeswari
Intisari Sains Medis Vol. 9 No. 3 (2018): (Available online: 1 December 2018)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1318.117 KB) | DOI: 10.15562/ism.v9i3.328

Abstract

Latar belakang: Kusta adalah penyakit infeksi yang menyebabkan masalah yang sangat kompleks baik dalam segi kesehatan, sosial, maupun ekonomi. Berdasarkan data WHO, jumlah kasus kusta baru pada tahun 2016 adalah sebesar 216.108 kasus (0,21 per 10.000 penduduk) dari 145 negara di dunia. Tujuan: Mengatahui peran sitokin dalam patogenesis kerusakan saraf pada penyakit kusta sehingga mempermudah proses klasifikasi kasus borderline dan memungkinkan pengobatan dini berdasarkan tipe kusta. Hasil:  Kusta adalah penyakit yang disebabkan oleh bakteri Mycobacterium leprae dan terutama menyerang saraf perifer. Manifestasi kusta dipengaruhi oleh respon imun, terutama respon imun yang diperantarain sel. Terdapat keterlibatan sitokin yang berbeda dalam kerusakan saraf pada kusta tipe pausibasiler dan multibasiler. Simpulan: Manifestasi klinis kusta dipengaruhi oleh keseimbangan sitokin-sitokin dari Th1 dan Th2.
Hubungan profil lipid dan C-reactive protein (CRP) dengan derajat stenosis koroner pada penyakit jantung koroner stabil Katarina Noviyanti; Edward Kurnia Setiawan L
Intisari Sains Medis Vol. 10 No. 1 (2019): (Available online 1 April 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (279.833 KB) | DOI: 10.15562/ism.v10i1.332

Abstract

Background: Inflammation and dyslipidemia play an important role in the formation of atherosclerotic plaques in stable coronary artery disease (SCAD). The stenosis degree indicates a visual evaluation of the percentage reduction of coronary diameter compare to normal coronary. This study aims to determine the correlation of lipid profiles, CRP with the stenosis degree in SCAD.Methods: Cross sectional study was carried in 31 patients with SCAD who had coronary angiography at Dr. Kariadi. The study used secondary data from February - March 2018 at Dr. Kariadi Semarang. Secondary data included levels of total cholesterol, LDL, HDL, triglycerides and CRP. The stenosis degree was obtained from coronary angiography in percentage units. Statistical analysis used Spearman Correlation test, p < 0,05 was considered significant.Result: Median (min-max) levels of total cholesterol, HDL, LDL, triglycerides, CRP and stenosis degrees respectively are 156 (104-283), 41 (13-67), 102 (60-190), 116 (60- 216), 1.50 (0.50-6.54), 70 (20-100). Correlation of total cholesterol, HDL, LDL, triglycerides and CRP levels with a degree of coronary stenosis are (r = 0.123; p = 0.511), (r = -0.132; p = 0.479), (r = 0.073; p = 0.697), (r = 0.117; p = 0.531), (r = 0.026; p = 0.891).Conclusion: There are no significant correlation between lipid profiles, CRP with stenosis degree in SCAD. The effect of statin drugs has an effect on dyslipidemia and as an anti-inflammatory.
Sistem skoring faktor risiko sebagai model prediktor kejadian cedera sfingter ani obstetrik Arufiadi Anityo Mochtar; Surahman Hakim; Tyas Priyatini; Shirley Anggraini Tunggadewi; Erwinanto Erwinanto; M Thohar Arifin
Intisari Sains Medis Vol. 9 No. 3 (2018): (Available online: 1 December 2018)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (462.52 KB) | DOI: 10.15562/ism.v9i3.333

Abstract

ABSTRACTIntroduction: anal sphincter injury is one of the complications that often occur in vaginal delivery. The impact of anal sphincter injury after vaginal delivery can reduce quality of life by causing various complaints such fecal incontinence, voiding disorders, sexual dysfunction, perineal pain and rectovaginal fistula. Assessment of risk factors is important to watch out for patients who are more prone to injury to the anal sphincter. This study aims to obtain a scoring system of various antenatal risk factors that can be used to predict the incidence of obstetric anal sphincter injury.Methods: This study is a diagnostic test that uses predictive factors for various risk factors for anal sphincter injury in vaginal delivery. The research was carried out in maternity service at Dr. Cipto Mangunkusumo General Hospital and Fatmawati General Hospital in the period February - July 2016. Analysis of the data in this study uses SPSS version 21.0. The analysis test used in this study is the calculation of odds ratio, logistic regression test, ROC curve analysis test to assess sensitivity and specificity of the scoring system.Results: Nulliparous, estimated fetal weight ≥ 3,500 gr, perineum length ≤ 25 mm, estimated head circumference ≥33.5 were risk factors for obstetric anal sphincter injury (OR> 1; p <0.05). Through the scoring modeling system all risk factors can be converted into scores 1. The probability values of scores 1, 2, 3, 4 are 7%, 30%, 70% and 90% respectively. The sensitivity and specificity of the scoring system developed were 61.3% and 91.3% with a cut-off score of 2.Conclusion: By knowing the prediction score before delivery, action can be taken to prevent the possibility of sphincter injury in obstetrics.
Korelasi kadar leptin serum terhadap derajat penyakit dermatitis atopik Gde Ngurah Arya Ariwangsa; Made Wardhana; Luh Made Mas Rusyati
Intisari Sains Medis Vol. 10 No. 1 (2019): (Available online 1 April 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (537.647 KB) | DOI: 10.15562/ism.v10i1.334

Abstract

Background: Atopic dermatitis (AD) is a chronic and residual skin inflammatory disease in which the symptoms include intense itching, chronic exacerbations and remissions, with multifactorial etiologies. The role of leptin in DA is closely related to polarization of T cells towards Th1 cells resulting in the release of pro-inflammatory cytokines.Methods: A cross-sectional study was conducted among 30 atopic dermatitis patients at Sanglah General Hospital in the period of July-August 2018. The leptin examination was carried out using the ELISA method. Data analysis were performed using SPSS version 25.0 software with the Spearman correlation test to determine the relationship between levels of serum leptin and the severity of atopic dermatitis based on SCORAD.Results: Most of the respondents were females (66.7%) with an average leptin level was 25.75 + 18.21 pg/dL. The results showed a significant negative correlation between the level of serum leptin and the severity of DA (SCORAD) (r: -0.127; p: 0.043). However, there was a significant positive correlation between pH of the skin and SCORAD (r: 0.810 and p: <0.001).Conclusions: There is a negative correlation between level of serum leptin and SCORAD but it has a strong positive correlation between the pH of the skin and SCORAD.

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