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INDONESIA
ISM (Intisari Sains Medis) : Jurnal Kedokteran
Published by Universitas Udayana
ISSN : 25033638     EISSN : -     DOI : -
Core Subject : Health, Science,
Intisari Sains Medis is published by Medical Scientific Community, Indonesia. Intisari Sains Medis is an international, multidisciplinary, peer-reviewed, open access journal accepts papers for publication in all aspects of Science Digest, Medical Research Development, Research Medical Field and Theory. We also publish cases from third world country, that is considered very rare and special cases.
Arjuna Subject : -
Articles 1,063 Documents
Faktor yang berhubungan dengan perilaku tes HIV pada ibu hamil di Puskesmas Abiansemal I Ni Luh Putu Suci Hary Purwani; Yuliana Yuliana; I Nyoman Gede Wardana
Intisari Sains Medis Vol. 11 No. 3 (2020): (Available online: 1 December 2020)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (306.272 KB) | DOI: 10.15562/ism.v11i3.696

Abstract

Background: HIV transmission vertically within children or infants become essential point of view for reducing HIV cases. Aim: The study aims to find out the related factors of HIV test behavior among pregnant women in public primary healthcare Abiansemal I.Method: This study used analytical cross-sectional design and consecutive sampling among pregnant women who have routine examination in public primary healthcare Abiansemal I Badung, Bali. Respondents asked to fill a self-administered questionnaire from Health Belief Model to asses of respondent’s perception about HIV screening test.Result and conclusion: There are 43 pregnant women as respondents with mean age 27 years. Of 49 respondents, 71.4% is pregnant women with equal or below of high school education. 16.3% of respondents did not work and 51% have a good knowledge about HIV. Through bivariate analysis have found gestational age, education level, knowledge, and risk perception have significant associations that can included into multivariate analysis (p<0.25). From multivariate analysis, we found that risk perception have independent association to HIV test among pregnant women (p<0.05; OR 0.121; 95%CI 0.021 – 0.690). Penularan HIV kepada anak-anak atau bayi menjadi fokus permasalahan penting dalam program reduksi kasus HIV. Tujuan: Untuk mengetahui faktor yang berhubungan dengan perilaku tes HIV (human immunodeficiency virus) pada ibu hamil di Puskesmas Abiansemal I.Metode: Penelitian ini menggunakan desain cross-sectional analitik dengan purposive sampling pada sampel ibu hamil yang rutin melakukan pemeriksaan kehamilan di Wilayah Pelayanan Puskesmas Abiansemal I, Badung. Seluruh responden mengisi kuesioner adaptasi health belief model untuk menilai persepsi responden mengenai tes skrining HIV.Hasil dan simpulan: Total responden pada penelitian ini adalah 49 orang dengan rerata usia 27 tahun. Dari 49 responden tersebut, 71,4% memiliki riwayat pendidikan terakhir, yaitu di bawah atau sama dengan sekolah menengah atas (SMA). Terdapat 16,3% responden yang tidak bekerja dan 51% responden memiliki pengetahuan yang baik mengenai HIV. Melalui analisis bivariat, ditemukan bahwa usia kehamilan, tingkat pendidikan, pengetahuan, dan persepsi risiko memiliki hubungan yang dapat diinklusi dalam analisis multivariat (p<0,25).  Pada analisis multivariat, ditemukan bahwa persepsi risiko memiliki hubungan independen terhadap perilaku tes HIV ibu hamil (p<0,05; OR 0,121; 95%IK 0,021 - 0,690).
Faktor – faktor yang berhubungan dengan luaran klinis pasien tetanus di RSUP Sanglah pada bulan Januari 2018 – Oktober 2019 Tu Bagus Adnan Angga Prawira; Ni Putu Witari; Kumara Tini
Intisari Sains Medis Vol. 11 No. 3 (2020): (Available online: 1 December 2020)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (305.281 KB) | DOI: 10.15562/ism.v11i3.697

Abstract

Introduction: Tetanuseis anwacute diseasedthat attacks thewperipheral nervousgsystem, causedebyfthe tetanospamin toxinvproducedbbymthe bacterium Clostridiumbtetani. Tetanusfcan be lifecthreatening andgis stillra healthgproblem forxdevelopingvcountries, includingvIndonesia. Thisfstudy aimsbto determinekthe characteristicskand relationships of age, incubation period, tetanus degree, and complications of the clinical outcome of tetanus patients in Sanglah Hospital Denpasar in January 2018 - October22019.Method: Thissstudy is accross-sectionall studyeof 333samples thatfwere takenxfrom secondaryddata infthe formvof medicalbrecords atvSanglah HospitalcDenpasar.rDatalwerekanalyzeduusing SPSS software version 23.Result: Tetanusfpatients with age <60 years found in 19 people, >60 years found in 14 people. The incubation period <7 days was found in 7 people, >7 days was found in 26 people. TetanussAblett I / mild scores was found in 1 person, II/moderate in 18 people, III/severe in 9 people, IV/very severe in 5 people. Cardiovascular complications was found in 16 people, respiratory system in 11 people, no complications in 6 people. Good clinical outcomes (survive) in 19 people, death in 14 people.Conclusion: There is no relationship between age and incubation period on clinical outcomes Theregis afstrong relationshiptbetween thebdegree of tetanusvand complicationsvwith clinicalboutcomes with significantgvalues respectively of p=0.008i (correlationbcoefficient = 0.443) and p=0.004 (correlationfcoefficient = 0.487).  Latar Belakang: Tetanusrrmerupakant tpenyakit akutr yangr menyerangr susunany sarafhtepi, disebabkanlloleh toxin tetanospamin yangfdihasilkan oleh bakteri Clostridiummtetani. Penyakitrtetanus dapatbmengancam nyawabdan masihbmerupakan masalahxkesehatan bagiz negara-negara berkembang, termasukkkIndonesia. Penelitiannnini bertujuanf funtuktt mengetahui karakteristike dan hubunganefaktorrusia, masa inkubasi, derajat tetanus, dan komplikasi terhadap luaran klinis pasien tetanus di RSUP Sanglah Denpasar pada bulan januari 2018 – Oktoberr2019.Metode: Penelitiangini merupakanvpenelitian potongslintang pada233 sampeltyang diambilhdari datacsekunder berupazrekam medisddi RSUPCSanglahcDenpasar.wData dianalisisjmenggunakanrsoftware SPSSsversi 23.Hasil: Pasien tetanus dengan usia < 60 tahun dijumpai 19 orang, > 60 tahun sebanyak 14 orang. Masa inkubasi < 7 hari dijumpai pada 7 orang, > 7 hari dijumpai pada 26 orang. Tetanus skoreAblett I/ringan dijumpai 1 orang, II/sedang sebanyak 18 orang, III/berat sebanyak 9 orang, IV/sangat berat sebanyak 5 orang. Komplikasi kardiovaskular dijumpai 16 orang, sistem pernafasan 11 orang, tidak ada komplikasi pada 6 orang. Luaran klinis yang bertahan hidup = 19 orang, meninggal = 14 orang.Simpulan: Tidak terdapat hubungan antara faktor usia dan masa inkubasi terhadap luaran klinis. Terdapat hubungan yang kuat antara derajat tetanus dan komplikasi dengan luaran klinis dengan nilai signifikan berturut-turut sebesar p=0,008 (koefisienckorelasi 0,443) dan p=0,004 (koefisientkorelasi 0,487).
Cochlear implantation in a child with cystic cochleovestibular malformation: a case report Komang Andi Dwi Saputra; Adriyani Hartayanti
Intisari Sains Medis Vol. 11 No. 3 (2020): (Available online: 1 December 2020)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (711.928 KB) | DOI: 10.15562/ism.v11i3.699

Abstract

Background: The inner ear and internal auditory canal (IAC) malformations account for 20% of congenital sensorineural hearing loss in children. The cystic cochleovestibular malformation is one of the congenital malformations in the cochlea, in which the cochlea is empty, unpartitioned, and cystic. The dimension of the cochlea is normal. This presents a significant challenge even to the most experienced clinicians because of difficulty in the surgery with facial nerve anomaly and gusher, choice and placement of electrode, and increased risk of meningitis after the procedure. This study aims to report the procedure of cochlear implantation in one case of cystic cochleovestibular (IP type I) malformation, which still became a challenge in the otology field.Case Presentation: We reported one case of 5 years old boy with bilateral cystic vestibular malformation who underwent cochlear implantation on the left ear. The patient was diagnosed with bilateral profound congenital sensorineural hearing loss. He already used hearing aids on both ears but gained limited improvements. Peri-operative perilymph gusher was happened and was stopped by plugging the cochleostomy hole using fascia. The patient showed good condition after the procedure. Although facial nerve lesion occurred after the operation, it was improved by giving steroids. There is no sign of cerebrospinal fluid leaks such as rhinorrhea, otorrhea, or meningitis.Conclusion: This report showed good outcomes following cochlear implantation in cystic cochleovestibular malformation.
Hubungan konsumsi kopi hitam terhadap tekanan darah pada perokok dewasa Ni Made Sarah Manacika Naraswari; I Wayan Gde Sutadarma; Ni Nyoman Ayu Dewi
Intisari Sains Medis Vol. 11 No. 3 (2020): (Available online: 1 December 2020)
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Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (300.356 KB) | DOI: 10.15562/ism.v%vi%i.700

Abstract

Background: Unhealthy lifestyles such as smoking and consuming coffee can affect blood pressure.Aim: The study aims to evaluate the association between black coffee consumption and hypertension.Method: This study design was cross-sectional with 93 participants. Data taken from questionnaire measurements and blood pressure measurements at a time.Results and conclusion: The results showed 79.6% had abnormal blood pressure and 20.4% had normal blood pressure. In this study male smoker workers who consumed black coffee were statistically related to blood pressure (p <0.05). Pola hidup yang tidak sehat seperti merokok dan mengkonsumsi kopi dapat mempengaruhi tekanan idarah.Tujuan: Untuk mengevaluasi hubungan konsumsi kopi hitam dan tekanan darah.Metode: Desain penelitian ini cross-sectional dengan 93 peserta sampel. Data yang diambil berasal dari pengukuran kuisioner dan pengukuran tekanan darah sewaktu.Hasil dan simpulan: Terdapat 79,6% sampel memiliki tekanan idarah tidak normal dan 20,4% memiliki tekanan darah normal. Dalam penelitian ini pekerja laki-laki perokok yang mengkonsumsi kopi hitam berhubungan secara statistik dengan tekanani darah (p < 0,05). 
Prevalensi dan faktor penentu prediabetes pada wanita muda obesitas di Kota Denpasar tahun 2019 Dinda Anggita Meiwita Sari; Desak Ketut Ernawati; Agung Nova Mahendra; I Wayan Weta
Intisari Sains Medis Vol. 11 No. 3 (2020): (Available online: 1 December 2020)
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Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (288.884 KB) | DOI: 10.15562/ism.v11i3.701

Abstract

Background: The prevalence of prediabetic state in population is such a hard project to be confirmed within an increased number of obese population.Aim: The study aims to define the prevalence of prediabetes among obese young women (body mass index, BMI >25 kg/m2) in Denpasar.Methods: Research variables namely physical activity, food pattern, anthropometric values for identify level of obesity (light BMI 25-30, severe BMI >30 kg/m2), tipe of obesity (perifer obesity waist circumference <80 cm,  and central obesity waist circumference ≥80 cm), as well as fasting blood glucose (normal <100 mg/dL, prediabetes -125 mg/dL).Results: the prediabetes prevalence of subjects is 38,1%. All subjects 42 (100%) have light daily physical activity, with high mean of cholesterol intake (more than 200mg) and low of PUFA intake (less than 10% of fat intake). Pre-diabetic subjects have higher waist circumference (visceral fat) than subjects with normal blood glucose (p=0.023). In contrary, that was no relationship between subcutaneous fat (bicep and tricep skinfold) to prediabetic state(p >0,05). Central obesity was significant OR 1,76 (1,33-2,33) risk of prediabetes compared to peripheral obesity (p= 0,023). However, there was not significant risk (OR 2,67 (0,738-9,63) (p= 0,130)) of severe obesity to be prediabetes compared to light obesity. Latar Belakang: Peningkatan prevalensi obesitas bersamaan dengan prevalensi diabetes melitus tipe 2. Prevalensi prediabetes sangat susah dideteksi pada suatu populasi.Tujuan: untuk mengetahui prevalensi dan faktor penentu prediabetes pada wanita muda obese (indeks massa tubuh, IMT >25) di Denpasar.Metode: Penelitian ini termasuk studi cross-sectional dengan variabel penelitian, meliputi aktivitas fisik, pola makan, antropometri pada tingkat obesitas (obesitas ringan IMT 25-30 kg/m2, obesitas berat IMT>30 kg/m2) dan jenis obesitas (obesitas perifer lingkar perut <80 cm, obesitas sentral lingkar perut >80 cm), serta kadar glukosa darah puasa (normal <100 mg/dL, prediabetes -125 mg/dL).Hasil dan Simpulan: prevalensi prediabetes dari subjek adalah 38,1%. Semua subjek 42 (100%) memiliki aktivitas fisik harian yang ringan, dengan rata-rata asupan kolesterol yang tinggi (>200mg) dan asupan PUFA (pure unsaturated fatty-acid) yang rendah (<10% dari asupan lemak). Subjek dengan prediabetes mempunyai lingkar perut (lemak visceral) lebih besar dibandingkan dengan subjek dengan kadar gua darah normal (p=0,023). Sebaliknya, tidak didapat hubungan antara lemak subkutan (lipatan kulit bisep dan trisep) dengan kejadian prediabetes (p>0,05). Obesitas sentral bermakna berisiko menderita prediabetes OR 1,76 (1,33-2,33) dibandingkan dengan obesitas perifer (p= 0,023). Namun, tidak ada risiko yang signifikan [OR 2,67; (0,738-9,63) (p= 0,130)] obesitas berat menjadi prediabetes dibandingkan dengan obesitas ringan. 
Penanganan pasien status hiperglikemik hiperosmoler yang disertai pankreatitis akut Ni Nyoman Trisna Yuliharti Tersinanda; Ketut Suastika
Intisari Sains Medis Vol. 11 No. 3 (2020): (Available online: 1 December 2020)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (688.846 KB) | DOI: 10.15562/ism.v11i3.702

Abstract

Introduction. The hyperosmolar hyperglycemic state is a dangerous complication that can arise with diabetes mellitus. The emergent treatment is necessary to reinstate hemodynamic stability, as mortality rates for the hyperosmolar hyperglycemic state are exceptionally high and can have multiple complications.Case. A 40-year-old male presented unresponsive to the emergency department. Upon arrival, the patient examination was consistent with dehydration and tachycardia. Review of systems included a one-week history of epigastrial pain, nausea and vomiting without a history of diabetes. The presenting blood sugar level was 1099 mg/dl with high osmolarity. Abdominal ultrasound revealed peripancreatic fluid suspicious for acute pancreatitis. Following successful treatment of acute pancreatitis and hyperglycemia with fluid and insulin, his serum glucose and pancreatic enzyme level decreased to normal range. The patient recovered and was discharged in stable condition.Conclusion. This case study postulates that the correlation between hyperosmolar hyperglycemic state and pancreatitis may be explained by two causal relationships, one of them is the hyperosmolar hyperglycemic state can be induced by ischemic pancreatitis. This is important because hyperglycemia superimposed on any ischemic insult can increase the risk of multiorgan failure, as with our patient. Thus, recognition and management of resulting complications need to be emergent. Pandahuluan. Status hiperglikemik hiperosmoler merupakan komplikasi berbahaya dari diabetes melitus. Terapi yang cepat sangat penting untuk mengembalikan stabilitas hemodinamik, dimana angka mortalitas untuk status hiperglikemik hiperosmoler sangat tinggi dan memiliki banyak komplikasi.Kasus. Seorang pria usia 40 tahun datang dalam keadaan penurunan kesadaran ke unit gawat darurat. Saat datang, pasien didapatkan dehidrasi dan takikardia dari pemeriksaan tanda vital. Didapatkan riwayat nyeri ulu hati sejak satu minggu, mual dan muntah tanpa riwayat diabetes sebelumnya. Kadar glukosa darah sewaktu saat itu 1099 mg/dl dengan osmolaritas yang tinggi. Dari pencitraan ultrasound abdomen didapatkan cairan peripankreatik yang mengarah ke pankreatitis akut. Dengan berhasilnya terapi cairan dan insulin untuk penanganan pankreatitis akut dan hiperglikemia, kadar glukosa darah dan enzim pankreas pasien ini membaik ke rentang normal. Kondisi pasien membaik dan dipulangkan dalam keadaan yang stabil.Kesimpulan. Laporan kasus ini menggambarkan korelasi antara status hiperglikemik hiperosmoler dan pankreatitis yang dapat dijelaskan dengan hubungan dua arah, dimana salah satunya bahwa status hiperglikemik hiperosmoler dapat dicetuskan oleh pankreatitis iskemik. Hal ini penting karena hiperglikemia yang dicetuskan oleh kondisi iskemik dapat meningkatkan risiko gagal multiorgan, seperti pada kasus ini. Sehingga, deteksi dan penanganan dari komplikasi ini harus dilakukan dengan segera.
Analisis rasio BUN/kreatinin pada pasien infark miokard akut di RSUP Dr. Wahidin Sudirohusodo, Makassar, Indonesia Andi Ahmad Tarau; Sulina Yanti Wibawa; Tenri Esa; Darmawati E. Rauf
Intisari Sains Medis Vol. 11 No. 3 (2020): (Available online: 1 December 2020)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (394.716 KB) | DOI: 10.15562/ism.v11i3.704

Abstract

Background: Heart disease is one of the highest mortality diseases and 30% is caused by acute myocardial infarction (AMI). Kidney disease is one of the complications that occurred in patients with acute myocardial infarction.  Several previous studies have reported a high incidence of Acute Kidney Injury (AKI) in patients with AMI (10-27%); the incidence is more elevated when accompanied by cardiogenic shock (50%). Serum BUN and creatinine tests are used to monitor the course and prognosis of renal disorder. This study aims to analyze the BUN/creatinine ratio in IMA patients.Methods: A retrospective cohort study by taking secondary data from medical records in 80 AMI patients (STEMI and NSTEMI) at Dr. Wahidin Sudirohusodo Hospital, Makassar, for January 2017-December 2018. The variables assessed in this study were age, gender, diagnosis, history of the disease, BUN, creatinine, and BUN/creatinine ratio. Data were analyzed using SPSS version 17 for Windows.Results: There was a significant difference between the first examination of ureum (p<0.001), creatinine (p=0.047), and the ratio of BUN/creatinine (p<0.001) with the second examination during treatment in IMA patients, which was higher at the second examination, but there was no association between BUN/creatinine ratio of IMA patients at the first examination with the incidence of renal disorder during treatment (p=0.757).Conclusion: A significant increase of urea and creatinine levels, as well as BUN/creatinine ratio, was found in AMI patients treated at Dr. Wahidin Sudirohusodo Hospital, Makassar. However, no association was found between an increase in the BUN/creatinine ratio and the patient's renal impairment.  Latar Belakang: Penyakit jantung merupakan salah satu penyebab kematian tertinggi dan sebanyak 30% disebabkan oleh infark miokard akut (IMA). Penyakit ginjal merupakan salah satu komplikasi yang dapat terjadi pada pasien infark miokard akut. Beberapa penelitian sebelumnya telah melaporkan tingginya insiden AKI pada pasien IMA (10-27%), insidennya semakin tinggi bila disertai syok kardiogenik (50%). Tes serial BUN dan Kreatinin serum digunakan untuk memantau perjalanan dan prognosis penyakit ginjal. Penelitian ini bertujuan untuk menganalisis hubungan rasio BUN/kreatinin pada pasien IMA.Metode: Penelitian ini bersifat kohort retrospektif dengan mengambil data sekunder dari rekam medis pada 80 pasien IMA (STEMI dan NSTEMI) yang dirawat di RSUP DR. Wahidin Sudirohusodo, Makassar periode Januari 2017-Desember 2018. Variabel yang dinilai pada penelitian ini meliputi usia, jenis kelamin, BUN, kreatinin, maupun rasio BUN/kreatinin serum. Data dianalisis dengan piranti lunak SPSS versi 17 untuk Windows. Hasil: Penelitian ini menunjukkan terdapat perbedaan bermakna pemeriksaan pertama ureum (p<0,001), kreatinin (p=0,047), dan rasio BUN/kreatinin (p<0,001) dengan pemeriksaan kedua selama perawatan pada pasien IMA, yaitu lebih tinggi pada pemeriksaan kedua, akan tetapi tidak terdapat hubungan rasio BUN/kreatinin pasien IMA pada pemeriksaan pertama dengan kejadian gangguan fungsi ginjal selama perawatan (p=0,757).Simpulan: Berdasarkan hasil penelitian, ditemukan peningkatan yang signifikan dari kadar ureum, kreatinin, dan rasio BUN/kreatinin pasien IMA yang dirawat di RSUP Dr. Wahidin Sudirohusodo, Makassar. Akan tetapi, rasio BUN/kreatinin tidak dapat dijadikan sebagai prediktor terhadap gangguan fungsi ginjal pasien IMA.
Hubungan Bayi Berat Lahir Rendah (BBLR) dengan kejadian hiperbilirubinemia pada neonatus di RSUD Wangaya, Bali, Indonesia Conchita Christal Yasadipura; I Wayan Bikin Suryawan; Anak Agung Made Sucipta
Intisari Sains Medis Vol. 11 No. 3 (2020): (Available online: 1 December 2020)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (278.144 KB) | DOI: 10.15562/ism.v11i3.706

Abstract

Background: Hyperbilirubinemia is one of the clinical phenomena most often found in newborns and occurs in 60% of > 35 weeks neonates and 80% of < 35 weeks neonates.  Hyperbilirubinemia is one of the most common causes of infant death (2012, SDKI).  Prevalence and severity of hyperbilirubinemia are found to be higher in newborns with low birth weight (LBW). This study aims to determine the relationship between LBW and incidence of hyperbilirubinemia in neonates at Wangaya hospital.Methods: This study was an observational analytic study with cross sectional approach conducted in August – September 2019 at Wangaya hospital.  The study subjects were 98 infants aged 0-28 days admitted to Wangaya hospital from August-September 2019 and met the inclusion and exclusion criteria. The subjects were taken by consecutive sampling. Bivariate analysis was performed using the Chi-Square test and calculation of prevalence ratio. Data were analyzed by SPSS version 17 for Windows.Results: In this study, 98 samples were obtained, and from all of them, as much as 24.5% were found to be LBW, and 9 of them were experiencing hyperbilirubinemia. The result of hypothesis testing with the Chi-Square test obtained p-value=0.042 and PR-value=2.13.Conclusions: A significant correlation between LBW and incidence of hyperbilirubinemia in neonates at Wangaya hospital and LBW is a risk factor for the incidence of hyperbilirubinemia in neonates.  Latar Belakang: Hiperbilirubinemia merupakan salah satu fenomena klinis yang paling sering ditemukan pada bayi baru lahir dimana hiperbilirubinemia terjadi pada 60% dari neonatus > 35 minggu dan 80% dari neonatus < 35 minggu. Berdasarkan SDKI tahun 2012, hiperbilirubinemia merupakan salah satu penyebab kematian bayi tersering. Pravelensi dan tingkat keparahan hiperbilirubinemia ditemukan lebih tinggi pada bayi berat lahir rendah (BBLR). Penelitian ini bertujuan untuk mengetahui hubungan BBLR dengan kejadian hiperbilirubinemia pada neonatus di RSUD Wangaya.Metode: Penelitian ini merupakan penelitian observasional analitik dengan pendekatan potong lintang yang dilaksanakan pada bulan Agustus – September 2019 di RSUD Wangaya. Subjek penelitian adalah bayi usia 0-28 hari yang dirawat di RSUD Wangaya selama bulan Agustus – September 2019 yang memenuhi kriteria inklusi dan eksklusi. Pengambilan sampel penelitian dilakukan secara consecutive sampling. Dilakukan analisis bivariat menggunakan uji Chi-Square dan menggunakan perhitungan rasio prevalensi. Data dianalisis dengan SPSS versi 17 untuk Windows.Hasil: Pada penelitian ini didapatkan sampel sebanyak 98 sampel, dimana didapatkan sampel BBLR sebesar 24,5% dan 9 sampel diantaranya mengalami hiperbilirubinemia. Hasil uji hipotesis dengan uji Chi-Square diperoleh nilai p=0,042 dan nilai RP=2,13.Simpulan: Terdapat hubungan yang bermakna antara BBLR dengan hiperbilirubinemia pada nenonatus di RSUD Wangaya dan BBLR merupakan faktor resiko terhadap kejadian hiperbilirubinemia pada neonatus.
High ureum and creatinine level in 18-year-old male: first diagnosed with chronic kidney disease I Made Dwi Payana; Ni Nengah Tuti Arianthi; I Made Sila Darmana
Intisari Sains Medis Vol. 11 No. 1 (2020): (Available online: 1 April 2020)
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Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (551.423 KB) | DOI: 10.15562/ism.v11i1.708

Abstract

Introduction: Chronic Kidney Disease (CKD) needs to be rapidly diagnosed and treated correctly. The classic patient characteristics were anaemia, hypertension, oedema, albuminuria and decrease of renal function.  In a few cases, CKD can occur in an atypical patient, such as in young age.Case report: We herein report a case of an 18-year-old male with Renal failure.  The patient noted to be anaemic, fatigue, oedema, hypertension which is consisted of features typical of Chronic kidney disease.  Laboratory examination revealed low haemoglobin level, high ureum and creatinin, and albuminuria. The patient underwent hemodialysis and was given Packed Red Cell (PRC) transfusions.Conclusion: CKD had to be suspected of all age so that it can be rapidly diagnosed and treated correctly.
Penyembuhan lesi periapikal melalui perawatan apeksifikasi dengan kalsium hidroksida pada gigi permanen muda Putu Ratna Kusumadewi Giri
Intisari Sains Medis Vol. 11 No. 3 (2020): (Available online: 1 December 2020)
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Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (440.3 KB) | DOI: 10.15562/ism.v11i3.709

Abstract

Background: Principle treatment of non-vital teeth with open apex is not different from the endodontic treatment of non-vital teeth, including cleaning and shaping root canals and obturation of root canals with filling materials. Chemomechanical cleansing of the root canal by administering intracanal drugs to help close the apex and formed the apex barrier. The treatment that can be done is Apexification. Apexification aims to stimulate further development or to continue the process of forming a tooth apex that has not yet fully grown but has already experienced pulp death by forming hard tissue in the apex area of the tooth. The material often used for apexification is Calcium hydroxide (Ca(OH)2) because of its ability to stimulate the hard tissue around the apex as an apical calcific barrier.Case report: A 15-year-old male patient had broken teeth five years ago, never experienced swelling, but often felt pain. The tooth was filled not long after it broke two months ago. It started to hurt when biting. The objective examination showed, on element 21, there was a composite fill in the mesial to distal region, vitality tests using CE (-), percussion (+) and palpation (-). The periapical radiographs showed a radiopaque area on the crown of tooth 21 in the 2/3 area of the crown. At the end of the apex, it appears not completely closed, and there is a radiolucent image of about 4mm. The action on tooth 21 was performed root canal treatment and calcium hydroxide application to the root canal and was controlled. Conclusion: The result of treatment after six months of control started to show the apical barrier at the apex area, and then the crown was fixed permanently. Latar belakang: Perawatan gigi non vital dengan apeks terbuka pada prinsipnya tidak berbeda dengan perawatan endodontik gigi non vital, yaitu meliputi pembersihan dan pembentukan saluran akar, disinfeksi saluran akar dan obturasi saluran akar dengan bahan pengisi. Pembersihan saluran akar secara kemomekanis dengan pemberian obat-obatan intrakanal untuk membantu penutupan apeks dan membentuk barrier apeks. Perawatan yang dapat dilakukan yaitu Apeksifikasi.  Apeksifikasi bertujuan untuk merangsang perkembangan lebih lanjut atau meneruskan proses pembentukan apeks gigi yang belum tumbuh sempurna tetapi sudah mengalami kematian pulpa dengan membentuk jaringan keras pada daerah apeks gigi. Bahan yang sering digunakan untuk apeksifikasi adalah Kalsium hidroksida (Ca(OH)2), karena kemampuannya merangsang jaringan keras di sekitar apeks, sebagai apical calcific barrier. Laporan kasus: Pasien laki-laki berusia 15 tahun giginya patah 5 tahun yang lalu, tidak pernah mengalami pembengkakan, tetapi sering terasa nyeri. Gigi tersebut sudah ditambal tidak lama setelah patah, dan sejak 2 bulan yang lalu mulai terasa sakit saat menggigit. Pemeriksaan objektif menunjukkan, pada elemen 21 nampak tumpatan komposit pada daerah mesial sampai distal, tes vitalitas menggunakan CE (-), perkusi (+) dan palpasi (-). Hasil pemeriksaan radiografi periapikal menunjukkan terdapat daerah radiopaque pada mahkota gigi 21 didaerah 2/3 mahkota yang mengenai mesial dan distal. Pada ujung apeks nampak belum tertutup sempurna dan terdapat gambaran radiolusen yang berbatas tidak jelas sekitar 4mm. Tindakan pada gigi 21 dilakukan perawatan saluran akar dan aplikasi kalsium hidroksida pada saluran akar dan dilakukan kontrol.Kesimpulan: Hasil perawatan setelah kontrol 6 bulan mulai nampak apical barrier pada daerah apeks kemudian dilakukan tumpatan permanen pada mahkota.

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