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ISM (Intisari Sains Medis) : Jurnal Kedokteran

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Published by Universitas Udayana

ISSN : 25033638 EISSN : - DOI : -

Core Subject : Health, Science,

Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology

Intisari Sains Medis is published by Medical Scientific Community, Indonesia. Intisari Sains Medis is an international, multidisciplinary, peer-reviewed, open access journal accepts papers for publication in all aspects of Science Digest, Medical Research Development, Research Medical Field and Theory. We also publish cases from third world country, that is considered very rare and special cases.

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Articles 1,063 Documents

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Korelasi volume prostat terhadap derajat lower urinary tract symptoms Jufriady Ismy; Sarah Safira; Iskandar Zakaria
Intisari Sains Medis Vol. 11 No. 1 (2020): (Available online: 1 April 2020)
Publisher : DiscoverSys Inc.

Introduction: Benign prostatic hyperplasia is a health problem whose incidence ranks second highest in the field of urology. One of the cause is the more severe the complaint that arises is the heavier prostat volume which can cause the iritative and obstructive symptoms or better known as lower urinary tract symptoms(LUTS) which will be assessed based of international prostate symptoms score (IPSS). This study aims to determine prostate volume correlation with lower urinary tract symptoms severity in RSUD dr. Zainoel Abidin Banda Aceh. Knowledge of the volume of the prostate is important in management of patients with benign prostatic hyperplasia.Method: This study uses the Cross Sectional design by selecting respondents in accidental sampling with a total of 31 patient. The data obtained were then analyzed by the Spearman test.Result: The univariat data shows that 18 patient (58.1%)Â are in Grade III (31-50 cc) and the most coming patient have LUTS scoring symptoms level on moderate (8-19) are 12 patient (38.7%) and severe symptoms (20-35) are 17 patient (54.8%). The results of prostate volume with lower urinary tract symptoms data analysis show that the p-value = 0.323 (p>0.05).Conclusion: The results of this study indicate that the prostate volume doesnâ€™t have correlation with lower urinary tract symptoms severity in patient with benign prostatic hyperplasia in RSUD dr. Zainoel Abidin Banda Aceh.Â Latar Belakang: Benign prostatic hyperplasia (BPH) merupakan masalah kesehatan yang insidensinya menempati urutan kedua tertinggi di bidang urologi. Salah satu penyebab semakin beratnya keluhan yang muncul adalah semakin besarnya volume prostat dan dapat menyebabkan gejala klinis berupa gejala iritatif dan obstruktif atau lebih dikenal dengan lower urinary tract symptoms (LUTS) yang akan dinilai berdasarkan international prostate symptoms score (IPSS). Metode: Penelitian ini bertujuan untuk mengetahui korelasi volume prostat dengan derajat lower urinary tract symptoms di RSUD dr. Zainoel Abidin Banda Aceh. Pengetahuan tentang volume prostat sangat penting dalam menangani pasien-pasien dengan benign prostatic hyperplasia. Studi ini menggunakan desain Cross Sectional dengan memilih responden secara accidental sampling dengan jumlah sebanyak 31 pasien.Hasil: Data yang didapat kemudian dianalisis dengan uji Spearman. Hasil analisis data univariat menunjukkan bahwa 18 orang pasien (58,1%) memiliki volume prostat Grade III (31-50 cc) dan paling banyak pasien yang memiliki skor derajat LUTS sedang (8-19) yaitu sebanyak 12 pasien (38,7%) dan derajat LUTS berat (20-35) sebanyak 17 pasien (54,8%). Hasil analisis data volume prostat dengan derajat LUTS menunjukkan bahwa nilai p-value = 0,323 (p>0,05).Simpulan: Hasil penelitian ini menunjukkan bahwa volume prostat tidak memiliki korelasi dengan derajat LUTS pasien BPH di RSUD dr. Zainoel Abidin Banda Aceh.

Kenpaullone (CDK2 Inhibitor dan GSK-3? Inhibitor) sebagai agen otoprotektif pada pasien kemoterapi berbasis cisplatin: tinjauan pustaka Ida Bagus Wisnu Widiarta; Anbiya Khairul Umam; I Putu Santhi Dewantara
Intisari Sains Medis Vol. 11 No. 3 (2020): (Available online: 1 December 2020)
Publisher : DiscoverSys Inc.

Background: Malignancies are one of the diseases with the most sufferers, almost all country in the world has a number of these diseases. Cisplatin-based chemotherapy regimens have long been the gold standard in the treatment of various soft tissue malignancies. Despite many beneficial cisplatin features, it also has serious side effects, which are nephrotoxicity, neurotoxicity, and ototoxicity. This literature study aims to theoretically review the role of kenpaullone (CDK2 Inhibitor and GSK-3? Inhibitor) as an autoprotective agent in cisplatin-based chemotherapy patients.Methods: The literature review approach is used in this study. Sources of reading come from relevant and appropriate journals and books from PubMed and Google Scholar.Results: Cisplatin is thought to selectively damages the outer hair cells within the organ of Corti, spiral ganglion cells, and cells within the stria vascularis. It is reducing the formation of free radicals as otoprotective strategies by maintaining glutathione levels and antioxidant activity. Kenpaullone provided significant protection against cisplatin-induced ototoxicity when delivered by tran tympanic injection in zebrafish, mice, and rats. Kenpaullone has proven to directly inhibit cyclin-dependent kinase 2 (CDK2) and Glycogen synthesis kinase-3, thereby attenuating cisplatin-induced mitochondrial ROS production caspase 3/7-mediated cell death. Cisplatin can cause ototoxicity in the manifestation of hearing loss; thus, an otoprotector is needed to prevent this side effect. Kenpaullone is a CDK2 inhibitor and GSK-3 inhibitor that can reduce damage to outer hair cells induced by cisplatin to prevent ototoxic hearing loss.Conclusion: The results of this study indicate that various literature studies show that kenpaullone (CDK2 Inhibitor and GSK-3? Inhibitor) can be used as an autoprotective agent in cisplatin-based chemotherapy patients. Latar Belakang: Keganasan merupakan salah satu penyakit yang memiliki jumlah pasien terbanyak, hampir seluruh negara di dunia memiliki jumlah penderita penyakit tersebut. Kemoterapi berbasis cisplatin telah lama menjadi baku emas untuk terapi pada beberapa keganasan jaringan lunak. Selain memberikan banyak keuntungan, cisplatin juga menimbulkan efek samping yang berat seperti nefrotoksik, neurotoksik, dan ototoksik. Studi tinjauan pustaka ini bertujuan untuk meninjau secara teoritis peran kenpaullone (CDK2 Inhibitor dan GSK-3? Inhibitor) sebagai agen otoprotektif pada pasien kemoterapi berbasis cisplatin.Metode: Dalam penulisan ini digunakan metode tinjauan pustaka. Sumber bacaan berasal jurnal-jurnal dan buku-buku yang relevan dan sesuai dari PubMed maupun Google Scholar.Hasil: Diduga bahwa cisplatin secara selektif merusak bagian sel luar disertai organ korti, sel ganglia spiral, dan sel dengan stria vaskularis. Strategi otoprotektif termasuk menurunkan pembentukan radikal bebas dengan menjaga level gluthione dan aktivitas antioksidan. Kenpaullone memberikan efek protektif signifikan terhadap ototoksisitas akibat terapi cisplatin ketika dinjeksikan secara transtimpani pada ikan zebra, dan tikus. Kenpaullone terbukti secara langsung menginhibisi Cyclin-Dependent Kinase 2 (CDK-2) dan Glycogen Synthesis Kinase-3 (GSK-3), menurukan produksi ROS mitokondria yang diinduksi oleh cisplatin serta caspase 3/7 yang memediasi kematian sel. Sehingga hal tersebut dapat mencegah terjadinya gangguan pendengaran akibat ototoksik.Kesimpulan: Hasil tinjauan pustaka ini menunjukkan bahwa berbagai studi literatur menunjukkan bahwa kenpaullone (CDK2 Inhibitor dan GSK-3? Inhibitor) dapat dipergunakan sebagai agen otoprotektif pada pasien kemoterapi berbasis cisplatin.

A case of secondary syphilis with stage four HIV infection accompanied with tuberculous lymphadenitis in bisexual man Ni Made Dwi Puspawati; Ni Nyoman Suryawati; Prima Sanjiwani S. Sudarsa
Intisari Sains Medis Vol. 11 No. 3 (2020): (Available online: 1 December 2020)
Publisher : DiscoverSys Inc.

Introduction: Sexually transmitted infections (STIs) is still a major health issue nowadays. Several studies have shown an increased incidence of STIs in the group of man who has sex with man (MSM) and bisexuals when compared to heterosexual men or women. This is inseparable from risky sexual behaviour practiced by this population, so it is not impossible for individual in this population to be suffering from more than one STI.Case description: We report one case of secondary syphilis with fourth stage HIV infection accompanied with tuberculous lymphadenitis in a bisexual man.Conclusion: Management of each specific condition have to in accordance with treatment standards guideline. Long term evaluation regarding patient compliance, laboratory serology test, and further education regarding the disease and transmission are mandatory.

The understanding of using universal precaution in medical student, ca-assistant and resident in the Faculty of Medicine, Universitas Udayana, Bali-Indonesia Tham Hong Yuan; I Wayan Niryana; Putu Anda Tusta Adiputra; Made Agus Dwianthara Sueta
Intisari Sains Medis Vol. 11 No. 2 (2020): (Available online: 1 August 2020)
Publisher : DiscoverSys Inc.

Introduction: This study was reported that among medical students, Co-Assistant (Co-Ass) and resident, several factors such as the academic overload in addition to the studentsâ€™ non-school activities might contribute to this situation. There is a lack of universal precaution studies among Universitas Udayana students in Bali and in Sanglah Hospital. Thus, the aim of this descriptive study was to examine the understanding of using universal precaution among three categories of students as well as doctors in Universitas Udayana.Method: Study design using a cross sectional model. Data were obtained from 90 current university students and doctors.Result: The highest questionnaire overall scores were obtained was 83 and the lowest scores were 43. The understanding of PPE among medical students, Co-Ass, resident significantly differ in the understanding of PPE (p<0.001). Resident is significantly different (p<0.001) than the other two groups, but there is no significant difference between the Co-Ass and Medical students.Conclusion: This study provides an overall understanding of universal precautions among medical students, Co-Ass and resident in Universitas Udayana. Findings will serve as a basis for future researchers to conduct future intervention studies.

Dislipidemia pada penderita nefropati diabetik di Rumah Sakit Umum Pusat Sanglah Denpasar, Bali tahun 2018 I Nyoman Santa Wijaya; Desak Gde Diah Dharma Santhi; Anak Agung Wiradewi Lestari
Intisari Sains Medis Vol. 11 No. 2 (2020): (Available online: 1 August 2020)
Publisher : DiscoverSys Inc.

Background: Diabeticcnephropathy isaa commonacomplication of diabetes and the main cause of chronic kidney disease in developed countries. Diabetics develop toward nephropathy in about 40% of cases. This condition is characterized by increased albuminuria or decreased glomerular filtration levels. Patient with diabetic nephropathy and dyslipidemia have higher renal parameters such as blood ureum and serum creatinine.Aim: Â The study aims to determine gender, age, blood pressure, smoking habit, and lipid profile, ureum and creatinine characteristic in patients with diabetic nephropathy.Method: This research was descriptive cross-sectional approach applying 40 patient with diabetic nephropaty who visited Sanglah General Hospital Denpasar in Januari-Desember 2018. The sampling technique used consecutive sampling techniques and used secondary data in the form of medical records.Â Results and Conclusion: Most of diabetic nephropathy patients was male (55%), belong to age range of 51 to 60 years (50%), had hypertension (55%) and smoking history (15%).Â Lipid profile parameter found that diabetic nephropathy patients had 52% increase in triglycerides and 62.5% decrease in HDL levels.Â Results for urea levels found that 57.5% samples had urea levels >23 mg/dL and 80% had creatinine levels >0.90 mg/dL.Â Â Latar Belakang: Nefropati diabetik adalahh komplikasi umum dari diabetes dan penyebab utama penyakit ginjal kronis di negara maju. Sekitar 40% penderita diabetes berkembang ke arah nefropati, dimana kondisi ini ditandai dengan peningkatan albuminuria atau penurunan tingkat filtrasi glomerulus. Penderita nefropati diabetik dengan dislipidemia memiliki parameter ginjal seperti ureum darah dan serum kreatinin yang lebih tinggi.Tujuan: Untuk mengetahui untuk mengetahui gambaran jenis kelamin, usia, tekanan darah dan riwayat merokok serta profil lipid, ureum dan keratinin padaapenderitaadiabetes mellitusstipe 2 (DMT2)ddengan nefropatii diabetik.Metodee: PenelitianNini bersifat deskritif dengann metode crosss-sectional. Sampel penelitiann adalah 40 orang penderita nefropati diabetik yang mmelakukan perawatann di RumahSSakit UmumPPusat (RSUP) SanglahDDenpasar pada bulan jJanuari â€“ Desember 2018. Teknik pengambilan sampel dalam penelitian ini menggunakan teknik consecutive samplingg dann menggunakann dataasekunder berupaarekam medis.Hasil dan Simpulan: Mayoritas pasien nefropati diabetik adalah berjenis kelamin laki-laki (55%), dengan umur bekisar 51 â€“ 60 tahun (50%), mengalami hipertensi (55%) dan memiliki riwayat merokok (15%). Gambaran profil lipid pasien nefropati diabetik didapatkan peningkatan trigliserida (52%) dan penurunan kadar HDL (62,5%). Hasil untuk parameter kadar ureum mendapatkan sebanyak 57,5% pasien memiliki kadar ureum >23 mg/dL dan sebanyak 80% memiliki kadar keratinin >0,90 mg/dL.

Profil pemberian nifedipine kombinasi metildopa dan MgSO4 pada pasien pre-eklamsi berat di Rumah Sakit Daerah Mangusada Badung Diana Putri; Agung Nova Mahendra; Agung Wiwiek Indrayanti; Gede Wirata
Intisari Sains Medis Vol. 11 No. 3 (2020): (Available online: 1 December 2020)
Publisher : DiscoverSys Inc.

Background: Nifedipine are recommended as first line drug choice for gestational hypertensior or severe pre-eclampsia to reduce coroner insufisiency (pectoral angina ofter cardiac infark). Aim: The study aims to determine the usage pattern of nifedipine combined with methyldopa and MgSO4 for patients with severe pre-eclampsia in RSD Mangusada Badung.Method: This study is a descriptive study with crossectional method for using the data of patient who seek treatment for severe pre-eclampsia at RSD Mangusada Badung in 2019. Nifedipine with some kind of combination aspecially anticonvulsant MgSO4 are given in the range of 2-4 days which is nifedipine are given orally and the MgSO4 are given by using IV line as a loading dose for the first step and maintenance treathment by infusion drip with appropriate monitoring. There were no monotherapy of nifedipine are found but using MgSO4 as a protocol for all the patient (100%) with severe pre-eclampsia as a convulsion prophylaxis.Results: The condision of severe pre-eclmpsia at RSD Mangusada Badung Tahun 2019 are followed by some patient’s characteristic are most prevalent in the age group of > 35 years as many as 9 people (56.25%), characteristic of pre-eclmpsia’s history as many as 5 people (55.56%), characteristic of deases history as many as 14 people (87.5%), characteristic of BMI (body mass index) are obesity degree I and II there are 11 people (68.8%) dan 4 people (25,0%) for each obesity’s character, characteristic of gestational age are most prevalent in the age group of 20-< 37 weeks as many as 10 people (62,5%) and all of them are without multiple pregnancy.Conclusion: The profile of nifedipine therapy for severe hypertension are given by using nifedipine orally combine with MgSO4 for convultion prophylaxis as a dominan result which is about 15 cases (93.75%) and all of them are showing there are no complication symptom. Nifedipine secara umum digunakan bagi pengobatan dan pencegahan insufisiensi koroner (terutama angina pektoris setelah infark jantung) dan sebagai terapi lini-1 pada hipertensi dalam kehamilan khususnya pada kejadian preeklampsia berat.Tujuan: Tujuan penelitian ini adalah untuk mengetahui profil pemberian nifedipine kombinasi metildopa dan MgSO4 pada pasien PEB (pre-eklamsi berat) di Rumah Sakit Daerah (RSD) Mangusada Badung.Metode: Penelitian ini merupakan penelitian deskriptif dengan metode crossestional pada pasien preeklamsia berat yang berobat di RSD Mangusada Badung tahun 2019. Profil pemberian nifedipine pada pasien preeklamsia berat di RSD Mangusada Badung tahun 2019 dengan pemberian terapi nifedipine dilakukan per oral dan antikonvulsan dalam hal ini MgSO4 dengan cara injeksi IV bolus dan drip. Tidak ada pemberian nifedipine monoterapi, melainkan pemberian anti konvulsan MgSO4 kepada semua pasien (100%) yang terdiagnose PEB.Hasil: Karakteristik pasien preeklamsia berat berdasarkan umur paling banyak pada kelompok usia > 35 tahun sebanyak 9 orang (56,25%) dengan pengulangan riwayat PEB/eklamsia berjumlah 5 orang (55,56%) dan paling banyak tanpa riwayat penyakit sebelumnya sejumlah 14 orang (87,5%), dengan kondisi IMT (index massa tubuh) didapatkan dominan obesitas I dan II yaitu masing-masing 11 orang (68,8%) dan 4 orang (25,0%) serta ditemukan paling banyak pada usia 20 minggu - <37 minggu yaitu 10 orang (62,5%) serta tidak ada yang memiliki kehamilan multiple.Simpulan: Profile pemberian nifedipine kombinasi dengan anti konvulsan sebanyak 15 orang (93,75%) dengan seluruhnya tidak ditemukan efek samping dan lama pengobatan di rumah sakit dengan kurun waktu 2-4 hari perawatan.

Prevalensi dan komplikasi pada penderita gagal ginjal kronik yang menjalani hemodialisa di Rumah Sakit Umum Pusat Sanglah Denpasar tahun 2018 Ida Ayu Ari Utami; Desak Gede Diah Dharma Santhi; Anak Agung Wiradewi Lestari
Intisari Sains Medis Vol. 11 No. 3 (2020): (Available online: 1 December 2020)
Publisher : DiscoverSys Inc.

Background: The prevalence of chronic kidney failure in Australia, Japan and Europe is 6-11%, increased relatively about 5-8% per year. Meanwhile, in Indonesia, the prevalence of chronic kidney failure is 0.2% of total. Only 60% of patients with chronic kidney failure had dialysis therapy.Aim: This study aims to determine the prevalence of patients with chronic kidney failure who do hemodialysis at RSUP Sanglah and to determine the description of complications in patients with chronic kidney failure who do hemodialysis at RSUP Sanglah.Method: This was a categorical descriptive study looking at medical records of chronic renal failure patients do hemodialysis at RSUP Sanglah in 2018 with a sample of 45 patients who had met the inclusion and exclusion criteria. The study sample consisted of chronic kidney failure patients do hemodialysis and complications.Results and conclusion: There were 16 patients with chronic renal failure do hemodialysis at RSUP Sanglah and there were complications consisting of complications of hypertension, hyperuremia, hyperkalemia, metabolic acidosis and anemia. Prevalensi gagal ginjal kronik di negara Australia, Jepang dan Eropa adalah 6 – 11%, terjadi peningkatan 5 – 8% pertahun. Sedangkan, di Indonesia terdapat prevalensi gagal ginjal kronik 0,2% dari penduduk di Indonesia. Hanya 60% dari pasien gagal ginjal kronik yang menjalani terapi dialisis.Tujuan: untuk mengetahui prevalensi pasien gagal ginjal kronik yang melakukan hemodialisis di Rumah Sakit Umum Pusat (RSUP) Sanglah dan untuk mengetahui gambaran komplikasi pada pasien gagal ginjal kronik yang melakukan hemodialisis di RSUP Sanglah.Metode: Penelitian ini merupakan penelitian deskriptif kategorik melihat dari catatan rekam medis pasien gagal ginjal kronik yang menjalani hemodialisis di RSUP Sanglah pada tahun 2018 dengan sampel sebanyak 45 pasien yang telah memenuhi kriteria inklusi dan eksklusi. Sampel penelitian terdiri dari pasien gagal ginjal kronik yang menjalani hemodialisis dan terdapat komplikasi.Hasil dan simpulan: Terdapat 16 pasien gagal ginjal kronik yang menjalani hemodialisis di RSUP Sanglah dan terdapat komplikasi yang terdiri dari komplikasi hipertensi, hiperuremia, hiperkalemia, asidosis metabolik dan anemia.

The characteristic of anxiety disorder among medical students of Universitas Udayana, Bali, Indonesia in the 2019 period Kuganesh Ravichandran; Dewa Ayu Shintya Dewi; I Wayan Aryabiantara
Intisari Sains Medis Vol. 11 No. 3 (2020): (Available online: 1 December 2020)
Publisher : DiscoverSys Inc.

Background: Anxiety is a normal stress reaction and can be beneficial in some dangerous situations. The symptoms are individual, whereas most of them include restlessness, feeling keyed up on edge, being easily fatigued, difficulty concentrating, irritability, muscle tension, and sleep disturbance. This study aims to determine the characteristic of anxiety disorder among medical students of Universitas Udayana, Bali, Indonesia, in the 2019 periodMethods: A cross-sectional study was conducted among 75 medical students who met the inclusion criteria in this study. The characteristic of anxiety disorders depicted in this study was the prevalence, anxiety severity, characteristic of anxiety, and possible stressors. Depression Anxiety and Stress Scale- 21 (DASS-21) used to assess anxiety among medical students. Data were analyzed descriptively using SPSS version 21 for Windows and presented in percentages.Results: From 75 medical students, 11 (14.67%) students were batch 2016, 25 (33.33%) students were batch 2017, and 39 (52.0%) students were batch 2018. Based on the DASS-21 score, there were 53 students (70.7%) experienced anxiety. According to the severity of anxiety, we found that the vast majority of students (45.3%) belong to the extremely severe anxiety group, followed by severe anxiety (20.8%), moderate anxiety (15.1%) and mild anxiety (11.3%).Conclusion: The characteristic of anxiety disorder among medical students were predominant by the severe anxiety group based on the DASS-21 score.

Hubungan perilaku penggunaan gadget terhadap miopia pada anak sekolah dasar kelas 6 di Kota Denpasar Gede Anantha Restu Permana; Komang Ayu Kartika Sari; Putu Aryani
Intisari Sains Medis Vol. 11 No. 2 (2020): (Available online: 1 August 2020)
Publisher : DiscoverSys Inc.

Introduction: Myopia is a state of vision in which light fall in front of retina that causes blurred appearance of distant objects. The prevalence of myopia in Indonesia reaches 25% in adults and 10-12% in children.Method: This study aimed to identify the relationship of gadget usage behavior and myopia on sixth grade of elementary school children in Denpasar. This study was conducted by analytical method with cross-sectional design. Gadget usage behavior included position, visibility, and duration of gadget usage which were measured by questionnaire. Myopia was measured by snellen chart.Â Samples of this study were 100 sixth grade children of Saraswati 2 Elementary School in Denpasar which were selected by simple random sampling technique.Result: Results of this study showed that there was no relationship between position of gadget usage and myopia (p value=0.059).Â There was a relationship between eye to gadget distance and myopia (p value=0.000). Â Duration of gadget usage per day was not related to myopia with (p value=0.490).Conclusion: The results of this study are useful for early prevention to children about risk factors of the gadget usage behavior towards myopia.Â Researchers suggest to other researchers to examine using other research methods and besides examining factors related to myopia such as genes, light intensity, and outdoor or indoor activities.Â Â Latar Belakang: Miopia merupakan keadaan penglihatan dimana cahaya jatuh di depan retina yang menyebabkan objek jauh terlihat kabur. Prevalensi miopia di Indonesia mencapai 25% pada orang dewasa dan 10-12% pada anak-anak. Penelitian ini bertujuan untuk mengidentifikasi dan menguraikan hubungan perilaku penggunaan gadget terhadap miopia pada anak sekolah dasar kelas 6 di Denpasar.Metode: Penelitian ini dilakukan dengan metode analitik menggunakan desain potong-lintang. Perilaku penggunaan gadget meliputi posisi, jarak pandang, dan durasi penggunaan gadget dinilai dengan menggunkan kuisioner. Status miopia sendiri diukur menggunakan snellen chart. Sampel penelitian adalah 100 orang anak kelas 6 di SD Saraswati 2 Denpasar yang dipilih melalui teknik simple random sampling.Hasil: Hasil penelitian ini menunjukkan bahwa tidak terdapat hubungan antara posisi penggunaan gadget terhadap miopia dengan nilai p=0,059. Terdapat hubungan antara jarak pandang penggunaan gadget terhadap miopia dengan nilai p=0,000. Durasi penggunaan gadget perhari tidak berhubungan terhadap miopia dengan nilai p=0,490.Simpulan: Hasil dari penelitian ini bermanfaat untuk melakukan pencegahan sejak dini kepada anak-anak tentang faktor risiko dari perilaku penggunaan gadget terhadap miopia. Peneliti menyarankan agar penelitian selanjutnya dilakukan dengan menggunakan metode penelitian lain serta meneliti pula faktor yang berhubungan dengan miopia seperti gen, intensitas cahaya, aktivitas luar ruangan dan dalam ruangan.

Karakteristik klinikopatologi osteokondroma di Rumah Sakit Umum Pusat Sanglah Denpasar periode tahun 2013 - 2018 I Gusti Ngurah Pratama Yuda Atmaja; I Wayan Juli Sumadi; Ni Putu Sriwidyani
Intisari Sains Medis Vol. 11 No. 3 (2020): (Available online: 1 December 2020)
Publisher : DiscoverSys Inc.

Background: Osteochondroma is a benign cartilage tumor which is quite a number of events with a clinical picture and quite varied pathology. The cause of osteochondroma is still not known with certainty. Data from osteocondroma cases in Indonesia especially in Bali are still very rarely found, even histopathological data registered at hospitals in Bali are still very rare. Aim: The study aims to determine the clinicopathological characteristics of osteochondroma patients in the Sanglah Hospital Denpasar for 5 years.Method: This research is a cross-sectional descriptive study conducted at the Sanglah Hospital using the histological data archive for the period 2013 - 2018. The sampling technique used total sampling, with a total sample of 32 people.Results: Most of the osteochondroma sufferers in this study were 59.4% male, while female sufferers were around 40.6%, with the most age range being 10 - 20 years (62.5%) and at least those aged > 20 years (15.6%). The most tumor location is the distal femur bone (37.5%). Most tumor size is at the size of 1-5 cm (78.1%). Most cases of osteochondroma based on the thickness of the hyaline cartilage cap are 1-3 mm (59.4%).Conclusion: The clinicopathological characteristics of osteochondroma patients by using histopathological data in the Sanglah Hospital shows that osteochondroma is more common in men. Osteokondroma merupakan salah satu tumor tulang rawan jinak yang angka kejadiannya cukup banyak dengan gambaran klinis dan gambaran patologinya cukup bervariasi. Penyebab osteokondroma masih belum dapat diketahui dengan pasti. Data dari kasus osteokondroma di Indonesia khususnya di Bali masih sangat jarang ditemukan, bahkan data histopatologi yang teregristasi di rumah sakit di Bali masih sangat jarang terjadi. Tujuan: Untuk mengetahui karakteristik klinikopatologi pasien osteokondroma di Rumah Sakit Umum Pusat (RSUP) Sanglah Denpasar selama 5 tahun.Metode: Penelitian ini merupakan penelitian deskriptif cross-sectional yang dilaksanakan di RSUP Sanglah menggunakan arsip data histologi periode tahun 2013 – 2018. Teknik pengambilan sampel menggunakan total sampling, dengan total jumlah sampel sebanyak 32 orang.Hasil: Sebagian besar penderita osteokondroma pada penelitian ini adalah laki – laki selitar 59,4%, sedangkan penderita perempuan sekitar 40,6%, dengan rentang usia terbanyak adalah 10 – 20 tahun (62,5%) dan paling sedikit pada usia > 20 tahun (15,6%). Lokasi tumor paling banyak adalah tulang distal femur (37,5%). Ukuran tumor paling banyak adalah pada ukuran 1 – 5 cm (78,1%). Kasus osteokondroma berdasarkan ketebalan tutup tulang rawan hialin terbanyak adalah pada ukuran 1 – 3 mm (59,4%).Simpulan: Karakteristik klinikopatologi pasien osteokondroma dengan menggunakan data histopatologi di RSUP Sanglah menunjukkan osteokondroma lebih banyak diderita oleh laki – laki.

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Bali

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Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name -

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Phone -

Journal Mail Official -

Editorial Address -

Location Kota denpasar, Bali INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
-

Contact Email
-

Phone
-

Journal Mail Official
-

Editorial Address
-

Location
Kota denpasar,

Bali

INDONESIA