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JCPS (Journal of Current Pharmaceutical Sciences)
Published by Universitas Muhammadiyah Banjarmasin
ISSN : 25982087     EISSN : 25982095     DOI : -
Core Subject : Health,
Medicine & Pharmacology
Journal of Current Pharmaceutical Sciences is a scholarly journal and expects to Publish articles related to the science of pharmaceutical science became the main focus of the problem at this time. This journal may publish research results as well as the results of theoretical studies and reviews. JCPS has had an ISSN print version 2598-2087 and has an online version 2598-2095 since Vo. 1 No.1 year 2017.
Arjuna Subject : -
Articles 13 Documents
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Search results for , issue "Vol 4 No 2 (2021): March 2021" : 13 Documents clear
Formula Optimization Of Orally Disintegrating Tablet Piroxicam with Superdisintegrant Pregelatinized Cassava Starch and Kollidon® CL prayoga fery yuniarto
JCPS (Journal of Current Pharmaceutical Sciences) Vol 4 No 2 (2021): March 2021
Publisher : LPPM - Universitas Muhammadiyah Banjarmasin

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Abstract

Piroxicam is a non steroidal anti inflammatory drug (NSAID) has poor solubility with delayed onset of action. This can be overcome by created drug delivery systems capable of accelerating the disintegration and dissolution of the tablet piroxicam as Orally Disintegrating Tablets (ODT). The combined of pregelatinized cassava starch and Kollidon® CL as superdisintegrant is expected to generate ODT piroxicam with good physical properties. Optimization by simplex lattice design method was applied to optimize ODT piroxicam. The optimum area was determined using superimposed contour plot of hardness, friability, wetting time, disintegration time, and dissolution at 3 minute used Design Expert software. The result showed that optimum of ODT piroxicam with optimum physical properties was pregelatinized cassava starch 12,13 mg Kollidon® CL 5,87 mg.
STUDI DESKRIPTIF SKRINING RESEP DI APOTEK X BANJARMASIN TAHUN 2019 Saftia Aryzki
JCPS (Journal of Current Pharmaceutical Sciences) Vol 4 No 2 (2021): March 2021
Publisher : LPPM - Universitas Muhammadiyah Banjarmasin

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Abstract

A prescription is a written request from a physician or dentist, to a pharmacist, both in paper and electronic form to provide and deliver medicine for patients, based on the regulation of the Minister of Health RI number 73 of 2016 concerning the standards of pharmacy services in pharmacies that in the service of prescriptions must perform administrative services that include the patient's name, age of the patient, patient's gender, weight of the patient, doctor's name, doctor's SIP number, doctor's addres, doctor’s phone number, doctor’s signature and recipe date. The purpose of this research is to know the percentage of the prescribed parameters of the administrative completeness in Banjarmasin X Pharmacy in 2019. Research conducted in Banjarmasin X pharmacy using non experimental design methods that are descriptive analytical. The population used in this study was 13,947 recipe sheets, with a sample of 389 prescription drugs at the Banjarmasin X Pharmacy in 2019. Sampling uses a randomized and propotional technique. The results showed from samples of 389 prescription sheets 0.26% that meet the administrative completeness of the recipe with the details of existing patient names 100%, doctor name 95.10%, doctor's address is 94.60%, doctor phone number 93.30%, recipe date 77.40%, doctor’s license number 66.80%, age patients 50.90%, doctor signature 31.40%, patient gender 7.50% and patient weight 2.80%.
STUDI LITERATUR EFEKTIFITAS PEMBERIAN KONSELING TERHADAP KEPATUHAN PASIEN HIPERTENSI DI BERBAGAI FASILITAS KESEHATAN Nida Anshofia Indriani; Herda Ariyani; Maria Ulfah
JCPS (Journal of Current Pharmaceutical Sciences) Vol 4 No 2 (2021): March 2021
Publisher : LPPM - Universitas Muhammadiyah Banjarmasin

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Various evidence states that counseling carried out by pharmacists can improve adherence to taking medication in hypertensive patients and even improve the outcome of therapy. This study aims to determine the effectiveness of counseling on the compliance of hypertensive patients in various health facilities. The research method used is the literature study method which is carried out by searching for scientific evidence and collecting literature from various trusted databases, namely Scince Direct, Scopus Google Scholar, Elsavier, SINTA. There are 12 literatures used in this study, consisting of 8 national journals indexed by SINTA 1-4, 2 international journals indexed by SCOPUS and 2 Proceedings of the research. The results showed that counseling provided by pharmacists were significant in increasing adherence, controlling sodium, fat intake and lowering blood pressure also improving the quality of life of patients. This research is expected to be material for further research on counseling to increase the effectiveness of therapy and can be an input for future government policies in overcoming hypertension emergencies so as to add strategies in providing effective pharmaceutical care counseling.
Formulasi Gel Hand Sanitizer dari Ekstrak Rimpang Kumala Tawar (Costus speciosus) sebagai Antiseptik Nur Mahdi; Deni Setiawan
JCPS (Journal of Current Pharmaceutical Sciences) Vol 4 No 2 (2021): March 2021
Publisher : LPPM - Universitas Muhammadiyah Banjarmasin

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Abstract

Saponin yang ada pada ekstrak kumala tawar (costus speciosus) berefek sebagai antibakteri. Sediaan gel di masyarakat lebih disukai karena penggunaannya yang praktik dan efisien. Tujuan penelitian ini adalah untuk memformulasikan gel hand sanitizer ekstrak kumala tawar serta potensinya sebagai antibakteri. Ekstrak Kumala Tawar terbagi pada 4 konsentrasi yang berbeda (F0 0%, FI 1%, FII 2% dan FIII 3%) diformulasikan dalam sediaan gel hand sanitizer menggunakan basis Carbopol. Evaluasi dari gel hand sanitizer meliputi karakteristik fisik (organoleptik, homogenitas, uji daya lekat dan uji daya sebar), karakteristik kimia (pH) dan karakteristik mikrobiologi (uji antibakteri). Hasil organoleptic menunjukkan semua formula berwarna cokelat dengan tekstur semi padat dan aroma khas Kumala Tawar. semua formula homogen. Pada Uji daya lekat Formula F0, FI, FII dan FIII menunjukkan hasil (3,18; 1,05; 1,24; dan 0,86 detik), uji daya sebar (3,64; 4,68; 6,44; dan 7,02 cm), pH (7,4; 7,1; 7,2 dan 6,4), uji antibakteri Ekstrak Kumala Tawar, FI, FII dan FIII hasil daya hambat menunjukkan ( 2,7; 1,33; 1,73 dan 2,06 mm). Tidak ada perbedaan signifikan pada uji pH, daya lekat, daya sebar dan uji antibakteri. Ekstrak Kumala Tawar hingga konsentrasi 3% dapat diformulasikan dalam sediaan gel hand sanitizer menggunakan basis Carbopol. Pada formula FII dan FIII menunjukkan stabilitas, karakteristik dan mempunyai efek antibakteri yang baik
AKTIVITAS ANTIBAKTER EKSTRAK ETANOLIK BIJI PEPAYA (Carica papaya L.): Narative Review emelda Emelda
JCPS (Journal of Current Pharmaceutical Sciences) Vol 4 No 2 (2021): March 2021
Publisher : LPPM - Universitas Muhammadiyah Banjarmasin

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Abstract

Bagian dari tanaman papaya yang juga tenyata memiliki kemampuan sebagai obat adalah bagian biji. Papaya memiliki banyak manfaat yang besar antara lain untuk melancarkan pencernaan, sebagai sumber antioksidan, bahkan mampu berfungsi sebagai antijamur dan bakteri. Tujuan dari review ini adalah memberikan ringkasan informasi mengenai ekstrak etanolik biji papaya terhadap aktivitas antibakteri. Informasi diperoleh dari systematic data base (Google schoolar, Pubmed, NCBI, Chimical database, dan proquest) yang terbit dalam 5 tahun terakhir. Berdasarkan pencarian diperoleh 13 artikel yang relevan. Hasil artikel yang didapatkan ekstrak etanolik biji papaya terbukti memiliki aktivitas antibakteri diantaranya terhadap bakteri Pseudomonas aeruginosa, Staphylococcus aureus, Bacillus cereus, Pasteurella multocida, Klebsiella pneumonia, Escherichia coli, Shigella dysentriae, dan Propionibacterium acnes dengan senyawa kimia serta derivatnya yang berperan yaitu Alkaloid (karpain), flavonoid, triterpenoid, fenol, dan steroid.
STUDI LITERATUR ANALISIS EFEK SAMPING OBAT PADA PASIEN TUBERKULOSIS Siti Rahmah; Herda Ariyani; Dedi Hartanto
JCPS (Journal of Current Pharmaceutical Sciences) Vol 4 No 2 (2021): March 2021
Publisher : LPPM - Universitas Muhammadiyah Banjarmasin

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Tuberculosis is a contagious disease caused by the bacteria Mycobacterium tuberculosis. The cause of tuberculosis treatment is often unsuccessful due to the emergence of drug side effects, which makes patients who experience drug side effects not adhering to treatment. This study aims to determine and identify any side effects that occur during treatment with OAT in tuberculosis patients. The research method used is literature study. The results showed that on average women who experienced drug side effects were women than men. The largest percentage of the body's organ systems that experience drug side effects are gastrointestinal, and the skin is the most common cause of adverse reactions. Common and dominant types of manifestations of drug side effects are nausea, itching, and lethargy. The majority of the score categories in this study obtained were in the "Maybe" category, and with the lowest "Certain" category. The side effects that you get depend on each individual, and not all individuals experience side effects due to the use of OAT. Keywords: Drugs side effects, Antituberculosis drugs, Naranjo scale, tuberculosis.
UJI AKTIFITAS SABUN CAIR KEWANITAAN EKSTRAK DAUN TABAT BARITO (Ficus deltoideus Jack) TERHADAP JAMUR Candida albicans SRI RAHAYU
JCPS (Journal of Current Pharmaceutical Sciences) Vol 4 No 2 (2021): March 2021
Publisher : LPPM - Universitas Muhammadiyah Banjarmasin

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Abstract

Ekstrak dibuat dengan cara maserasi
Hubungan HUBUNGAN MEDICATION BELIEFS TERHADAP KEPATUHAN MINUM OBAT ANTIHIPERTENSI PADA PASIEN DIABETES MELLITUS TIPE II Andrey Wahyudi
JCPS (Journal of Current Pharmaceutical Sciences) Vol 4 No 2 (2021): March 2021
Publisher : LPPM - Universitas Muhammadiyah Banjarmasin

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Abstract

Diabetes Mellitus adalah penyakit kronis yang terjadi ketika pankreas tidak lagi dapat membuat insulin, atau ketika tubuh tidak dapat menggunakan insulin yang diproduksi dengan baik. Sebuah desain penelitian korelasional, untuk memungkinkan peneliti menentukan hubungan antara keyakinan pengobatan dan kepatuhan pengobatan pada pasien diabetes mellitus. Sebuah populasi total direkrut untuk penelitian, dimana semua terdaftar pasien dewasa diundang untuk bergabung dengan penelitian secara sukarela dan persetujuan lisan diperoleh, setelah menjelaskan manfaat penelitian. Sebanyak 93 pasien dengan diabetes berpartisipasi dalam penelitian ini. Menggunakan Beliefs about Medication Questionnaire (BMQ)-spesific dan Kuesioner Medication Adherence Report Scale (MARS). Penelitian dilakukan di dua provinsi Indonesia yaitu jawa tengah, desa Leyangan, kecamatan Ungaran Timur dan kalimantan timur, kabupaten tapin. Populasi dari semua pasien Diabetes Mellitus tipe 2 dengan perawatan dibiayai oleh Badan Penyelenggara Jaminan Sosial (BPJS) dan biaya pribadi. Hasil penelitian menyimpulkan bahwa hasil P = 0,321 dengan nilai signifikansi 0,004 < 0,05 artinya ada hubungan antara keyakinan pasien dan tingkat kepatuhan pengobatan mereka. Oleh karena itu, untuk memperbaiki tingkat kepatuhan pengobatan, keyakinan pasien juga harus ditingkatkan.
Activity of N-Hexane, Ethyl Acetate and Methanol Extracts from Passiflora foetida Leaves as α-Glucosidase Enzyme Inhibitor Nita Triadisti; Irfan Zamzani
JCPS (Journal of Current Pharmaceutical Sciences) Vol 4 No 2 (2021): March 2021
Publisher : LPPM - Universitas Muhammadiyah Banjarmasin

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Abstract

Diabetes mellitus is a major health problem characterized by an increase in postprandial blood glucose levels, where α-glucosidase enzyme inhibitors are an effective therapeutic option. The limited choice of α-glucosidase enzyme inhibitors has triggered a study to obtain new α-glucosidase inhibitor candidates. Kelubut (Passiflora foetida) has been used for generations in the treatment of diabetes in Kalimantan, usually the roots and leaves are part of the plant used in the treatment of diabetes. Scientific data regarding α-glucosidase inhibition have not been reported. The extraction was carried out using the multilevel maceration method, while the α-glucosidase inhibition test was carried out by the spectrophotometric method using a microplate reader. The assay results showed that all extracts had inhibitory activity against α-glucosidase, and the best activity was the methanol extract of Passiflora foetida leaves with IC50 580.04 µg / mL
AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL DAUN CEMPEDAK (Artocarpus integer), NANGKA (Artocarpus heterophyllus), dan TARAP (Artocarpus odoratissimus) ASAL KALIMANTAN SELATAN Muhammad Ikhwan Rizki
JCPS (Journal of Current Pharmaceutical Sciences) Vol 4 No 2 (2021): March 2021
Publisher : LPPM - Universitas Muhammadiyah Banjarmasin

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Abstract

Antioksidan memiliki kemampuan dalam melawan atau menetralkan dari radikal bebas. Nangka (A. heterophyllus), cempedak (A. integer), dan tarap (A. odoratissimus) adalah tanaman yang banyak terdapat di Kalimantan Selatan. Belum pernah diteliti aktivitas antioksidan dari ketiga daun dari genus tersebut. Penelitian ini bertujuan untuk mengetahui kemampuan antioksidan dari ekstrak etanol daun nangka (A. heterophyllus), cempedak (A. integer), dan tarap (A. odoratissimus). Prosedur penelitian dimulai dari proses ekstraksi secara maserasi. Pelarut yang dipakai untuk ekstraksi yaitu etanol. Ekstrak cair kemudian diuapkan hingga didapat ekstrak kental. Ekstrak diuji antivitas antioksidan menggunakan pereaksi DPPH dengan Spektrofotometer UV-Vis. Selanjutnya dilakukan perhitungan nilai IC50. Aktivitas antioksidan ekstrak etanol daun nangka (A. heterophyllus) termasuk kategori sedang dengan nilai IC50 yaitu 151,7856 ppm, ekstrak etanol daun cempedak (A. integer) termasuk kategori aktif dengan nilai IC50 yaitu 52,7706 ppm, dan ekstrak etanol daun tarap (A. odoratissimus) kategori aktif dengan nilai IC50 yaitu 87,9513 ppm

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