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Contact Name
Solikhatun
Contact Email
solikhatun@ugm.ac.id
Phone
+62331334293
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jid@unej.ac.id
Editorial Address
Jl. Kalimantan 37 Kampus Tegalboto Jember 68121 Telp. 62 331 334293 Fax. 62 331 330225
Location
Kab. jember,
Jawa timur
INDONESIA
Jurnal Ilmu Dasar
Published by Universitas Jember
ISSN : 24425613     EISSN : -     DOI : https://doi.org/10.19184/jid.v24i2.36657
Jurnal ILMU DASAR (JID) is a national peer-reviewed and open access journal that publishes research papers encompasses all aspects of natural sciences including Mathematics, Physics, Chemistry and Biology. JID publishes 2 issues in 1 volume per year. First published, volume 1 issue 1, in January 2000 and avalaible in electronically since 2012 with ISSN 1411-5735 (Print) and avalaible in electronically since 2012 with ISSN 2442-5613 (online). Jurnal ILMU DASAR is accredited SINTA 3 by the Ministry of Education, Culture, Research, and Technology of the Republic of Indonesia (Kemendibukristek) No. 152/E/KPT/2023 (September 25, 2023), Ministry of Research, Technology and Higher Education of the Republic of Indonesia (RISTEKDIKTI), No. 200/M/KPT/2020 (December. 23, 2020). All accepted manuscripts will be published worldwide JID has been indexed in DOAJ, Dimension, OCLC WorldCat, PKP Index, Crossref, Google Scholar, Base, Garuda, and OneSearch. JID have been collaborated in KOBI-ID (Konsorsium Biologi Indonesia) and HKI (Himpunan Kimia Indonesia) since 2017.
Articles 415 Documents
The Effect of Synthetic Estrogen on Hepar Stucture And Level of SGOT and SGPT of Balb’C Female Mice (UMus musculus) Susantin Fajariyah; Eva Tyas Utami; Yunita Arisandi
Jurnal ILMU DASAR Vol 11 No 1 (2010)
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Jember

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Abstract

The objectives of this study were to observe the effect of synthetic estrogen (diethylstilbestrol/DES) on hepar structure and level of SGOT as well as SGPT of female mice (Mus musculus). Mice were gavage by DES dose 0.084 μg/g bb, 0.168 μg/g bb, 0.336 μg/g body weight, sesame oil and control. DES was treated by gavage for 15 days. Observation were performed liver structure contain of number of normal hepatocyte, and hepatocyte disruption (picnosis, vacuole cell, and necrosis), also SGOT-SGPT level. The result showed that DES effected to the disruption of hepatocyte particularly necrosis was relativity high in 0,168 μg/g bb DES treatment. SGOT and SGPT level on blood increased after DES treatment. 
Screening and Identification of Alkaloid Compounds in Kayu Kuning Stem (Arcangelisia Flava Merr) Restu Kartiko Widi; Titin Indriati
Jurnal ILMU DASAR Vol 8 No 1 (2007)
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Jember

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Abstract

Extraction of kayu kuning stem (Arcangelisia flava Merr) with petroleum ether, chloroform and methanol 80% to screen of alkaloid compound has been carried out. Extract of chloroform was added by 10% of NH3 solution and Al2O3, then put into column chromatography and flowed by chloroform. Eluat was tested by dragendorf reagant to know the present of the alkaloid compound. This eluat was identified by thin layer chromatography with chloroform-methanol (1:4 v/v) as a mobile phase. It gave four spots that had the Rf value of 0.78; 0.64; 0.41; 0.18. After these spots were added by dragendorf reagant, only the first spot gave positive result. Then the chloroform fraction was separated by column chromatography to take the fraction which had Rf value of about 0.78 and thenit was analyzed by spectroscopic method (uv-vis and infra red). The data suggested that the alkaloid compound was the pyridin alkaloids group.
Analysis of Quantitative Structure and Solubility Relationship for Organophospate Active Compounds Linear Model and Cluster Model Approach Is Fatimah; Jaka Nugraha
Jurnal ILMU DASAR Vol 8 No 1 (2007)
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Jember

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Abstract

Study on quantitative solubility and structure relationship of organophospate pesticide has been conducted. Aim of this research is to analyze relationship between characteristic physical properties (water solubility) of pesticide with molecular structure by a model that can be used to predict physical properties of new compound proposed to be pesticide compound. Analysis was done for 52 organopospate compounds and its water solubility data. The model predicted by 39 fagmental descriptor based on spesific structure of organophospate compound. Analysis used in modeling are cluster analysis, one way analysis of variance (ANOVA) and regression analysis. Result show water solubility of the pesticide compound positive effect by functional group of P=O, N-primer and C=O in the structure. Functional group of S (sulphur), fen (phenil) , C-aromatic, C1-C2, C3-C4, C5-C6, Ortho Aromatic, P=S, C-Cl and log(Mr) decrease water solubility. The model resulted by regression analysis using stepwise and best subset method is : Ln(1+watsol) = 11.0 - 0.352 n C (aromatic) - 5.41 n (P=S) - 1.55 n (C-Cl), F-value = 32.43 (sign. 0,000) , R2 = 0.67 dan S=2.643. The model can be used to predict the organoposphate water solubility.Keywords : QSPR, ANOVA, regression analysis, organophospate pesticide
The Synthesis Study of Sulfanilamide Analogue from Natural Substances Papaverine Alkaloid I Made Sudarma; Mulyanto Mulyanto
Jurnal ILMU DASAR Vol 9 No 2 (2008)
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Jember

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Abstract

The aim of this research was to synthesize sulfanilamide analogue from natural products papaverine alkaloid. Sulfanilamide is known as an antibiotic which has been used for treatment of infection. Theoretically papaverine could be converted to be sulfanilamide analogue by two steps reactions, first sulfonation of papaverine by sulfonic acid to produce sulfonyl chloride and second reaction of with ammoniac to produce. The formation of this product was analyzed by analytical thin layer chromatography and FT-IR. This analysis showed the formation of product quite difficult since the compound was easily reacted with water to form compound. Infrared spectra supported the formation of which showed vibrations at 1153.4 and 1265.2 Cm-1 due to absorption of sulfonyl group and at 3433.1 Cm-1 due to absorption of –OH group.
Effect of Hyperglikemic Conditions on Ovarian Structure and Estrous Cycle of Mice (Mus musculus L) Eva Tyas Utami
Jurnal ILMU DASAR Vol 10 No 2 (2009)
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Jember

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Abstract

Streptozotocin cause hyperglycemic condition in mice. The objective of this study was to determine whether the hyperglycemic conditioned by streptozotocin (STZ) has an impact at folicullar atretic and estrous cycle prolonged. Mice were injected by STZ until hyperglycemic condition was reached. The vaginal smear was recorded daily for twice estrous cycle. Mice were sacrificed soon after the last vaginal smear observation. The ovary was removed, prepared by parafin method and stained by hematoxylin-eosin.The result showed that hyperglycemic causes increasing the number of atretic follicles, decreasing the number of corpus luteum and prolonged of estrous cycle.
Testing Normality and Bandwith Estimation Using Kernel Method For Small Sample Size Netti Herawati; Khoirin Nisa
Jurnal ILMU DASAR Vol 10 No 1 (2009)
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Jember

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Abstract

This article aimed to study kernel method for testing normality and to determine the density function based on curve fitting technique (density plot) for small sample sizes. To obtain optimal bandwith we used Kullback-Leibler cross validation method. We compared the result using goodness of fit test by Kolmogorof Smirnov test statistics. The result showed that kernel method gave the same performance as Kolmogorof Smirnov for testing normality but easier and more convinient than Kolmogorof Smirnov does.
Characterization of Edamame Indigenous Rhizobia as a Candidate of Biofertilizer Sattya Arimurti
Jurnal ILMU DASAR Vol 10 No 1 (2009)
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Jember

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Abstract

Five isolates, named R1, R3, R4, R6 and R7, were successfully isolated from leguminous edamame nodules, and characterized as indigenous rhizobia bacteria. All isolates were grown in a YEMA medium containing antibiotics ampicillin, streptomycin, rifampicin, tetracycline, chloramphenicol or penicillin. Cultivation revealed that R3 can grow in a medium containing all antibiotics, but not for R1 when they grow in a medium containing rifampicin. R7 could not grow when the medium contain streptomycin and rifampicin. Furthermore, R4 and R6 only grow at medium containing tetracycline. it seemed that R1 and R3 are more resistant against some antibiotics comparing with others. When YEMA containing bromthymol blue 1% medium was used, R1 produced the yellowish acid and R3 produced blue alkali. R1 also utilized dulcitol and Lhistidin as carbon and nitrogen source. R3 utilize the carbon source from dulcitol but cannot utilize the nitrogen source from L-histidin. Base on these results above, it can be suggested that R1 and R3 identified as Rhizobium leguminosarum and Bradyrhizobium japonicum.
Chromatogram and Spectram Profiles Antimalarial Isolate from Dichloromethane Extract of Artocarpus champeden Spreng. Stem Bark Nuri Nuri
Jurnal ILMU DASAR Vol 8 No 2 (2007)
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Jember

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Abstract

The isolate which possessed antimalarial activity had been isolated from dichloromethane extract of Artocarpus champeden Spreng. Stem bark. The isolate inhibited Plasmodium falciparum growth in vitro by IC 0.024±0.011 μg/ml. Chromatogram and spectram of isolate analysis showed that it contained flavonol as a  major compound.
Effect of Substituting Pure Sucrose by Sugarcane Juice as Carbon Source on the Fermentation of Dextran Production Triantarti Triantarti; Hendro Santoso M
Jurnal ILMU DASAR Vol 8 No 2 (2007)
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Jember

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Abstract

Sucrose is a carbon source for dextran fermentation and it is also used as a substrate of dextransucrase enzyme for producing dextran.  Sugar cane juice containing sucrose as a main sugar, hence it is potential to be used as a cheap medium for dextran fermentation.  This research was conducted to study the dextran fermentation using sugar cane juice as a medium. Two main experiments were done in this research. The first experiment has been carried out to determine the optimum medium composition for dextran fermentation using pure sucrose as a carbon source by variations on type and concentrations of yeast extract and buffering minerals.  The second experiment was conducted to determine the effect of substituting pure sucrose in the fermentation medium by sugar cane juice. Fermentation was conducted at static condition, room temperature and 16-20 h fermentation time. The results showed that the optimum conditions for dextran fermentation using pure sucrose were sucrose 20%, yeast extract 0.75% (technical grade yeast extract was able to be used) and K2HPO4 minerals for buffering medium. Dextran production was able to reach 51 mg/g medium. The optimum medium composition and fermentation conditions were used as a control medium.  In the second experiment, pure sucrose in the control medium was substituted by sugar cane juice with variations of 0; 50, 75 and 100%. Technical grade yeast extract was still added at 0.75%.  The result showed that the higher sugar cane juice concentration the lower dextran production in the fermentation.  On the other hand, medium fermentation containing 100% sugar cane juice without yeast extract was able to produce 45 mg dextran/g medium, which was not significantly different to dextran production from control medium.  This experiment showed that sugar cane juice was a potential material as a cheap carbon source for dextran fermentation
Determination of Subsurface Structure of Landslide Area According to Interpretation of Resistivity Data Supeno Supeno; Nurul Priyantari; Gusfan Halik
Jurnal ILMU DASAR Vol 9 No 1 (2008)
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Jember

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Abstract

Resistivity method is a useful geophysical tool for investigating landslides. It can be used to estimate the subsurface structure of a landslide mass, the depth of the failure surface, and the lateral extent of a landslide. High resolution of resistivity data were obtained by applying Schlumberger configuration, while penetrating deepness was obtained by applying Vertical Electrical Sounding (VES) configuration. Interpretation of subsurface condition showed there was soil layer in survey area which was indicated as slip surface triggering the landslide.