Andalas obstetrics and gynecology journal
Andalas Obstetrics And Gynecology Journal (AOJ) (e-ISSN: 2579-8324) is a peer-reviewed, open-access national journal published by Universitas Andalas and is dedicated to publish and disseminate research articles, literature reviews, and case reports, in the field of obstetrics, gynecology, and other related disciplines.
Articles
35 Documents
Search results for
, issue
"Vol. 8 No. 1 (2024)"
:
35 Documents
clear
<![CDATA[From Molar Pregnancy, Thyrotoxicosis, to Pulmonary Hypertension: A Case Report ]]>
<![CDATA[Saputra, Rudi]]>;
<![CDATA[Azra, Dieni]]>;
<![CDATA[Aswad, Fidya Mayastri]]>;
<![CDATA[Nurtanio, Setyawan]]>
<![CDATA[ Andalas Obstetrics And Gynecology Journal Vol. 8 No. 1 (2024) ]]>
Publisher : <![CDATA[Fakultas Kedokteran Universitas Andalas ]]>
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
DOI: 10.25077/aoj.8.1.661-666.2024
<![CDATA[Background: Molar pregnancy is a benign condition with the dominant symptom being dark brown to bright red bleeding from the vagina. This disease can induce hyperthyroidism and result in pulmonary hypertension. This case report describes a patient who had molar pregnancy with thyrotoxicosis and pulmonary hypertension.Case: A 30-year-old woman presented with complaints of lower abdominal pain for the last month. The patient feels that her stomach has enlarged in the last 3 months. Other complaints include bleeding and observed bubbles from the birth canal, shortness of breath, and chest pain. The serum cobas β-hCG level of 7954.00 mIU/mL. On abdominal ultrasound examination, vesicles formed a honeycomb appearance, measuring 7.4 cm×5.3 cm. Hematologic laboratory tests revealed low TSH levels (<0.01 μIU/mL), T3 levels of 2.35 ng/ml, and FT4 levels of 2.62 ng/dL. The results of the echocardiography examination showed there is a high probability of pulmonary hypertension.Conclusion: Molar pregnancy can exacerbate thyrotoxicosis through hCG activity. Smoking and breastfeeding also have similar effects. Consequently, increased thyroid hormone levels can worsen or cause pulmonary hypertension.]]>
<![CDATA[THE ROLE OF MAGNESIUM SUPPLEMENTS ON HYPERTENSION IN PREGNANCY AND PREECLAMPSIA ]]>
<![CDATA[Nurwany, Raissa]]>;
<![CDATA[Ramadhina, Shafira Fitri]]>;
<![CDATA[Pariyana, Pariyana]]>
<![CDATA[ Andalas Obstetrics And Gynecology Journal Vol. 8 No. 1 (2024) ]]>
Publisher : <![CDATA[Fakultas Kedokteran Universitas Andalas ]]>
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
DOI: 10.25077/aoj.8.1.511-518.2024
<![CDATA[Objective:This article aims to discuss the effects of magnesium supplementation on clinical outcomes of pregnancy and highlights the benefits of magnesium supplementation in reducing the risk of hypertension in pregnancy and preeclampsia. Method: In this systematic review article, the author conducted a literature search using certain keywords and selected articles that were published from 2013-2023, can be accessed in full-text in pdf format, and are in Indonesian or English. The methods used were in accordance with the reporting guidelines provided in the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA-P). Results: After carefully searching the database and eliminating articles that were not related to the topic, 6 articles were obtained for review. Hypertension in pregnancy and preeclampsia are serious health problems that can harm both mother and baby. Magnesium supplements have been studied as a way to reduce the risk of hypertension in pregnancy and preeclampsia. Conclusion: Magnesium supplements may help reduce the risk of hypertension in pregnancy and preeclampsia.]]>
<![CDATA[Long-Term Risks of Early Initiation of Breastfeeding to Mothers and Infants in Asia: a Systematic Review ]]>
<![CDATA[Raisa Nurwany]]>;
<![CDATA[Syifa Alkaf]]>;
<![CDATA[Jeyaseelan, Ajay Varmaa]]>
<![CDATA[ Andalas Obstetrics And Gynecology Journal Vol. 8 No. 1 (2024) ]]>
Publisher : <![CDATA[Fakultas Kedokteran Universitas Andalas ]]>
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
DOI: 10.25077/aoj.8.1.502-510.2024
<![CDATA[Objective: This systematic review aims to determine the long-term risks of early initiation of breastfeeding in mothers and babies in Asia. Method: The method used in writing this literature review is systematization using keywords, namely "Early Initiation of Breastfeeding", "Breastfeeding", "ASI", "Asia", "Risk", "Baby and Mother", "Long Term Risk" , and "Benefits".A literature search was conducted using Google Scholar, Pubmed and NCBI databases. Results: From the results of a literature search based on keywords, 25 journals were obtained, of which seven journals met the criteria for long-term risk of IMD for mothers and babies in Asia. One study in this study used a systematic review, five studies used a retrospective cohort study, and one study used a cross-sectional study. The study found many positive risks and benefits of early initiation of breastfeeding for mothers and babies in the long term in Asia. Conclusion: Positive risks for babies include increasing immunity, reducing the risk of death, and preventing obesity. Meanwhile, long-term risks for mothers include accelerating uterine involution, preventing breast cancer, and reducing the risk of diabetes and prediabetes in mothers who have experienced gestational diabetes.]]>
<![CDATA[Differences of Fibronectin Levels in First Trimester Normal Pregnency and Miscarriage ]]>
<![CDATA[Fadhilah, Maisarah]]>;
<![CDATA[Utama, Bobby Indra]]>;
<![CDATA[Tofrizal, Tofrizal]]>
<![CDATA[ Andalas Obstetrics And Gynecology Journal Vol. 8 No. 1 (2024) ]]>
Publisher : <![CDATA[Fakultas Kedokteran Universitas Andalas ]]>
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
DOI: 10.25077/aoj.8.1.648-653.2024
<![CDATA[Introduction: Miscarriage is a reflection of the low quality of health in pregnant women. The incidence of miscarriage in the world accounts for 23 million (15%) of the 130 million births per year and up to 80% of miscarriages occur in the first trimester of pregnancy. Miscarriage will affect a woman's social, physical, and psychological. The complexity of the negative impact of miscarriage makes it necessary to pay special attention. Biomarker examination is needed to more accurately identify pregnancies at risk of miscarriage before the appearance of clinical symptoms. The use of fetal fibronectin (fFN) levels have been used as a marker of unexpected labor and as evidence of premature rupture of the fetal membranes. Normally fFN can be detected in cervical and vaginal secretions at <20 weeks gestation. The presence of fFN at >22 weeks gestation indicates disruption of the uteroplacental surface. Therefore, if screening for fibronectin levels using the Enzyme-Linked Immunosorbent Assay (ELISA) test can be carried out in the first trimester of pregnancy, there is a high possibility that miscarriage can be prevented.Method: The type of research is analytical observational research with a cross-sectional research design. The stored samples were examined for fibronectin levels using the ELISA test, which included 21 blood serum samples from normal pregnancy patients in the first trimester and 21 miscarriage samples.Results: The results of the ELISA test produced an average first-trimester normal pregnancy fibronectin level of 118.8 ± 18.4 ng/mL while the miscarriage fibronectin level was 208.2 ± 152.0 ng/mL. Data analysis using the Mann-Whitney test obtained a p-value = 0.138, which means there was no significant difference in fibronectin levels between normal pregnancy in the first trimester and miscarriage.Conclusion: This study concludes that fibronectin levels are not specific biomarkers in detecting miscarriage in the first trimester of pregnancy.]]>
<![CDATA[Management of Hyperprolactinemia Caused by Pituitary Microadenoma ]]>
<![CDATA[Muttaqin, Ibnu]]>;
<![CDATA[Yuad, Haviz]]>
<![CDATA[ Andalas Obstetrics And Gynecology Journal Vol. 8 No. 1 (2024) ]]>
Publisher : <![CDATA[Fakultas Kedokteran Universitas Andalas ]]>
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
DOI: 10.25077/aoj.8.1.642-647.2024
<![CDATA[Hyperprolactinemia is an increase in fasting levels of the hormone prolactin above 20 ng/ml in men and above 25 ng/ml in women. Hyperprolactinemia occurs more often in women of reproductive age, with a percentage of 9 – 17%. The etiology of hyperprolactinemia can occur due to abnormal pituitary secretions, systemic disease, use of drugs, damage to the hypothalamus-pituitary axis. A 33-year old female patient came to the FER Polyclinic at M. Djamil Hospital with complaints of not menstruating for the past 2 months. Irregular menstruation since 15 years ago, menstruation 2-3 times in 6 months, irregular cycle for 7-8 days. The patient also complained of a fluid like breast milk coming out of the breast for 5 years, initially the fluid came out in a trickle and then gradually reduced and now the fluid comes out occasionally if the breast is squeezed. From the supporting examinations carried out, it was found that the prolactin hormone level in this patient was 134.53, and the results of the MRI examination showed a mass measuring 1.05x1.12x0.5 mm, which was diagnosed as secondary amenorrhea, hyperprolactinemia, and suspected pituitary microadenoma. The patient will be monitored for general condition and vital signs, as well as consultations with colleagues involved, such as consultations to the Internal Medicine section, Endocrinology, Metabolic and Diabetes Subdivision.]]>
<![CDATA[Peritional Tuberculosis in Young Age Lady Miicking Gynecology Malignancy: a Case Report ]]>
<![CDATA[Sari, Lusi Jelita]]>;
<![CDATA[Antonius, Puja Agung]]>;
<![CDATA[Muhammad, Syamel]]>
<![CDATA[ Andalas Obstetrics And Gynecology Journal Vol. 8 No. 1 (2024) ]]>
Publisher : <![CDATA[Fakultas Kedokteran Universitas Andalas ]]>
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
DOI: 10.25077/aoj.8.1.654-660.2024
<![CDATA[Background : Peritoneal tuberculosis is one of the most challenging forms of extrapulmonary tuberculosis to diagnose. Extrapulmonary TB is very difficult to diagnose because of its non-specific signs and symptoms, thus it sometimes leads to a diagnosis of gynaecological malignancy such as advanced ovarian carcinoma. Case Report : A teenage girl, 12 years old, with a chief complaint of intermittent abdominal pain since the last 1 month. There was no history of an enlarged abdomen, fever and weight loss. Ultrasound examination revealed an irregular adnexal mass suggesting an ovarian malignancy with other possibilities of an infectious process. Diagnostic laparoscopy and peritoneal biopsy were performed on the patient. Intraoperatively, multiple friable nodular-mylar peritoneal masses with abdominopelvic attachments and fibrin fibres and white vesicles were found on the entire surface of the genitalia, peritoneum, and intestines. A mass biopsy was performed with histopathological results showing peritoneal tuberculosis. Currently, the patient is undergoing anti-tuberculosis drugs (OAT) treatment. Discussion : The diagnosis of this disease is difficult to establish. Symptoms are highly variable and non-specific and can lead to the wrong tumour pathology. The clinical characteristics are dominated by changes in general condition, abdominal pain and transit disorders, as well as masses (20 to 25%). The gold standard for definitive PTB diagnosis remains laparoscopy with peritoneal biopsy and subsequent pathological or microbiological confirmation. Yellow/white nodules in the peritoneum observed on the patient's laparoscopic images are the hallmark of wet peritoneal TB. Omental thickening and abdominal cocoon with matted small bowel are other classic laparoscopic findings for peritoneal TB. Conclusion: PTB has similar characteristics to peritoneal carcinoma, which makes diagnosis difficult for clinicians. Early and correct diagnosis of PT]]>
<![CDATA[PAPP-A Levels and IGF-1 Levels in Early-Onset Preeclampsia and Late-Onset Preeclampsia ]]>
<![CDATA[Soufal, Juan Habli]]>;
<![CDATA[Yusrawati, Yusrawati]]>;
<![CDATA[Basyir, Vaulinne]]>
<![CDATA[ Andalas Obstetrics And Gynecology Journal Vol. 8 No. 1 (2024) ]]>
Publisher : <![CDATA[Fakultas Kedokteran Universitas Andalas ]]>
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
DOI: 10.25077/aoj.8.1.519-524.2024
<![CDATA[Introduction: The pathophysiology of preeclampsy is not yet fully understood, but failure of tropoblast invasion and placentation, which is influenced by factors such as pregnancy-associated plasma protein A (PAPP-A) and insulin-like growth factor 1 (IGF-1), is thought to play a role. Aims: This study aimed to explore the difference in PAPP-A and IGF-1 levels between Early-Onset Preeclampsia (PEAD) and Late-Onset Preeclampsia (PEAL), assuming that the role of PAPP-A and IGF-1 is more significant in the pathogenesis of PEAD than PEAL. Methods: This is an analytical observational study with a cross-partition comparative study design. Clinical data were obtained at Dr. M. Djamil Padang Hospital, while PAPP-A and IGF-1 levels were measured at the Biomedical Laboratory of the Faculty of Medicine, Andalas University. Samples are tested according to reagent procedures and analyzed by experts.Results: Average PAPP-A levels were 2.45+0.35 pg/mL in the early onset preeclampsy group and 2.85+0.50 pg/mL in the late onset preeclampsy group. These two levels differed statistically significantly (p=0.006). That means that low levels of PAPP-A are associated with and play a role in the pathogenesis of early onset preeclampsy. Average IGF-1 levels were 4.66+0.91 pg/mL in the early onset preeclampsy group and 5.39+0.74 pg/mL in the late-onset preeclampsy group. These two levels differed statistically significantly (p=0.010). That means that low levels of IGF-1 are associated with and play a role in the pathogenesis of early onset preeclampsy. PAPP-A levels were significantly positively correlated with IGF-1 levels (p=0.000). Conclusion: PAPP-A levels are lower in PEAD than PEAL, as are IGF-1 levels. These findings confirm the role of PAPP-A and IGF-1 in preeclampsia. Both of these hormones have potential as indicators and markers for the prediction and management of preeclampsy in early and late onset periods.]]>
<![CDATA[The Relationship of The Incident o Metabolic Syndrome and Overactive Bladder in Female Patients at DR. M. Djamil Padang in 2023 ]]>
<![CDATA[Anggra Pramana]]>;
<![CDATA[Utama, Bobby Indra]]>;
<![CDATA[Yetti, Husna]]>
<![CDATA[ Andalas Obstetrics And Gynecology Journal Vol. 8 No. 1 (2024) ]]>
Publisher : <![CDATA[Fakultas Kedokteran Universitas Andalas ]]>
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
DOI: 10.25077/aoj.8.1.538-547.2024
<![CDATA[Overactive Bladder (OAB) is a chronic medical condition that has a negative impact on an individual's health and quality of life. Cardiovascular problems are considered to be one of the risks associated with OAB where one of the higher cardiovascular parameters is metabolik syndrome. Aim to determine the relationship between  metabolik syndrome and Overactive Bladder in female patients at Dr. M. Djamil Hospital Padang. Quantitative research with a case control design using a questionnaire according to the Overactive Bladder Symptom Score (OABSS) and examination based on metabolik syndrome symptoms. The research was conducted at Dr. M. Djamil Hospital Padang in November 2022 to September 2023. There were 60 respondents who were divided into the OAB (28/60) and no-OAB group (32/60). Most respondents were aged 50-59 years (45,0%), graduated from high school (53.3%), worked as housewives (76.7%) and had diabetes mellitus (78,3%). In this study it was also found that 48,3% of respondents suffered from hypertension and 45.0% suffered from obesity. A total of 46.7% of respondents experienced OAB symptoms with a higher percentage of OAB found in the metabolik syndrome group (76,7%) than no-metabolik syndrome group (16.7%). Bivariate analysis found a relationship between metabolik syndrome and overactive bladder symptoms (p = 0.000) with metabolik syndrome affected the incidence of overactive bladder by 16.4 times (OR 16.42, (CI 95% 4.56-59.07). There is a relationship between metabolik syndrome and the incidence of OAB.]]>
<![CDATA[Factors Affecting the Age of Menopause in Padang City in 2023 ]]>
<![CDATA[Bennovry, Rizky Rivonda]]>;
<![CDATA[SA, Syahredi]]>;
<![CDATA[Utama, Bobby Indra]]>
<![CDATA[ Andalas Obstetrics And Gynecology Journal Vol. 8 No. 1 (2024) ]]>
Publisher : <![CDATA[Fakultas Kedokteran Universitas Andalas ]]>
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
DOI: 10.25077/aoj.8.1.525-537.2024
<![CDATA[Menopause is characterized by a consecutive period of amenorrhea lasting 12 months without any underlying causes or surgical interventions. The age at which menopause occurs can be influenced by various factors, including menarche, number of childbirths, body mass index, and the utilization of hormonal contraceptives. This study aims to determine the factors that influence the incidence of menopause in Padang. This study is an analytical research with a cross-sectional study design. The research was conducted in the working areas of all primary public health centers in Padang from Januari 2023 to September 2023. The sample consisted of middle-aged women who visited the working areas of all primary public health centers during the study period. This study is using a questionnaire as the research instrument and employing the simple random sampling technique to obtain a sample size of 124 participants. The data analysis was conducted using the Chi- Square test, and utilize the statistical software SPSS. A significant relationship between variables was defined if the p-value < 0.05. The results of this study revealed that the majority of respondents experienced early menarche (36.3%), had multiparous pregnancies (33.9%), had underweight body mass index (33.1%), used hormonal contraceptives (52.4%), and experienced late menopause (40.3%). The analysis showed a significant relationship (p<0.05) between the age of menarche (p=0.036) and parity (p=0.002) with the occurrence of menopause. However, there was no significant relationship (p>0.05) between body mass index (p=0.141) and history of contraceptive use (p=0.069) with the occurrence of menopause. This study found a significant relationship between the age of menarche and parity with the occurrence of menopause, while there was no significant relationship between body mass index and history of contraceptive use with the occurrence of menopause among middle-aged women visiting the primary public health center areas in Padang.]]>
<![CDATA[The Relationship of Vitamin D Topolycystic Ovary Syndrome (PCOS) Teenagers at Koto Tangah Padang District High School in 2022 ]]>
<![CDATA[Utomo, Hardi Cahyo]]>;
<![CDATA[Yuad, Haviz]]>;
<![CDATA[Burhan, Ida Rahmah]]>
<![CDATA[ Andalas Obstetrics And Gynecology Journal Vol. 8 No. 1 (2024) ]]>
Publisher : <![CDATA[Fakultas Kedokteran Universitas Andalas ]]>
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
DOI: 10.25077/aoj.8.1.615-631.2024
<![CDATA[PCOS is characterized by increased ovarian and adrenal androgen secretion, hyperandrogenic symptoms such as hirsutism, acne and/or alopecia, menstrual irregularities, and polycystic ovaries. The prevalence of PCOS in 2016 was 6−21% of reproductive age worldwide. PCOS is the most common female endocrine disorder with a prevalence of around 4-6% in women of reproductive age in Indonesia. Vitamin D deficiency can increase PCOS symptoms. The research design was cross-sectional. The study was conducted at SMA N 7, SMA N 8 and SMA N 13 Padang in Koto Tangah District in May-August 2022. The research sample was high school students who experienced menstrual cycle disorders and were willing to agree to informed consent for the study with a sample size of 59 respondents. Vitamin D levels were examined using the 25-Hydroxyvitamin D ELISA Kit. Data were analyzed by chi-square test. The results showed that 86.4% of respondents experienced vitamin D deficiency. Statistically there was a relationship between PCOS in adolescents accompanied by hyperandrogens and vitamin D levels, there was a relationship between PCOS in adolescents accompanied by obesity and vitamin D levels, there was no relationship between PCOS in adolescents accompanied by acanthosis nigrican and vitamin D levels, and there was no relationship between PCOS in adolescents accompanied by hyperandrogens, obesity and acanthosis nigrican with vitamin D levels in SMA Koto Tangah District Padang in 2022. The conclusion of this study is that there is a relationship between PCOS in adolescents accompanied by hyperandrogens and vitamin D levels and there is a relationship between PCOS in adolescents accompanied by obesity and vitamin D levels.]]>
