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Andalas obstetrics and gynecology journal
Published by Universitas Andalas
ISSN : 25798324     EISSN : 25798413     DOI : https://doi.org/10.25077/aogj
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Nursing Public Health
Andalas Obstetrics And Gynecology Journal (AOJ) (e-ISSN: 2579-8324) is a peer-reviewed, open-access national journal published by Universitas Andalas and is dedicated to publish and disseminate research articles, literature reviews, and case reports, in the field of obstetrics, gynecology, and other related disciplines.
Arjuna Subject : Kedokteran - Obstetrics and Gynaecology
Articles 469 Documents
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Urologic Morbidity in Surgery of Placenta Accreta Spectrum in Universitas Andalas Hospital Zulfiqar Yevri
Andalas Obstetrics And Gynecology Journal Vol. 8 No. 2 (2024)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.8.2.823-828.2024

Abstract

Background: Hysterectomy for placenta accreta spectrum disorders is known to be associated with urologic morbidity, including intentional or unintentional cystostomy, ureteral injury, and bladder fistula. Case: A 32year old woman with urine retention post total hysterectomy on indications placenta accreta spectrum Grade 3 type 4 S2 segment- 9 days ago, referred to Universitas Andalas Hospital. The patient complained difficulty to urinate, hematuria and supra pubic pain. Physical examination sign of acute abdomen unclear. A Pelvic abdominal ultrasound was performed, the result were Acites and complex acites, left renal hydronefrosis, cystitis and sludge gallblader. From the laboratory result found anemia, leucocytosis, trombositosis, ureum, creatinine and albumin were in normal limit, hyponatremia, hypokalemia, hypocalsemia. The patient were given antibiotics, blood transfusion and natrium, kalium and calcium correction. Cystoscopy was performed to explore the bladder, the result were found adhesion and ruptured at the posterior wall of the bladder a long 3 cm then proceed with laparotomy to repair the bladder and adhesiolisis. During hospitalization, the patient’s condition was good, hemodynamics was stable with sufficient diuresis. The patient was discharged on day 4 after laparotomy of bladder repair with temporary urine catheter installed. Discussion: This patient diagnose previously is placenta accreta spectrum with percreta graded so had a high risk of urologic morbidity. The bladder ruptured occurred after 9th day of hysterectomy. This can occur because the injury during dissection of the uterine vesicular fold undergoes necrosis and then become opens on the 9th day after hysterectomy. A multidisciplinary team should be made in management of placenta accreta spectrum. A team comprising a consultant maternal fetal medicine with pelvic surgery experienced, a blood bank team, an anesthesiologist, a urologist skilled, an interventional radiologist and an experienced neonatologist is advised. Keywords: urologic complication, placenta accreta, urologic morbidity
Unilateral Renal Cystic Disease Zulfiqar Yevri
Andalas Obstetrics And Gynecology Journal Vol. 8 No. 2 (2024)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.8.2.829-833.2024

Abstract

Background: Unilateral renal cystic disease of kidney is a non familial and non progressive disorder, characterized by replacement of the renal parenchyma by a cluster of multiple cysts with a normal contralateral kidney. Case: A 2-day-old newborn baby came to the Urology Department of the Perinatology Department of Andalas University Hospital. The baby with prenatal ultrasound results showed unilateral hydronephrosis and multicystic kidneys. From the postnatal ultrasound, it was found: The right kidney was normal in shape and size; clear differentiation of the cortex and medulla; the pelvic calyx system was not dilated; No stones were seen; There were multiple cystic lesions with regular borders in the renal cortex, the largest cyst size was 5.5x4 cm. The left kidney was normal in shape and size; clear differentiation of the cortex and medulla; The pelvic calyx system was not dilated; No stones or sludge were seen. The impression of multiple renal cysts. The patient was followed up for renal function and cyst development. Conclusion : This case highlights the importance of early diagnosis and follow-up in infants with unilateral renal cystic lesions. Differentiating URCD from other cystic renal diseases is essential for appropriate management and counseling. Further studies are needed to elucidate the pathogenesis and long-term outcomes of URCD.    
Analisis Beberapa Faktor Risiko Perdarahan Pasca Persalinan Di RSUD K.R.M.T. Wongsonegoro Kota Semarang Purnamasari, Intan; Handaria, Diana; Anggraheny, Hema Dewi
Andalas Obstetrics And Gynecology Journal Vol. 8 No. 1 (2024)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.8.1.599-609.2024

Abstract

Background: Postpartum haemorrhage is cumulative blood loss more than 1,000 ml after cesarean section or more than 500 ml after the fetus is born vaginally after the 3rd stage of labor is completed accompanied by signs of hypovolemia. Based on data from the Directorate of Maternal Health in 2010-2013, the biggest cause of maternal death is bleeding.Methods: This study used a quantitative analytic observational approach to case control. The cases in this study were mothers who were diagnosed with postpartum hemorrhage in 2021. While the controls in this study were mothers who were not diagnosed with postpartum hemorrhage in 2021. The sample used consecutive sampling technique.Results: Total sample of 306 people, namely 153 cases and 153 controls. In the chi square test and logistic regression analysis, namely age (p=0.234, OR1=1.495), parity (p=0.005, OR1=2.233, OR2=2.261), pregnancy interval (p=0.034, OR1=1.760), labor induction (p=0.268, OR1=1.356), cesarean section (p=0.001, OR1=0.014), retained placenta (p=0.001, OR1=15.457, OR2=7.245), and preeclampsia (p=0.012, OR1=0.329) .Conclusion: There is a relationship between parity, gestational spacing, cesarean section, retained placenta, and preeclampsia with postpartum hemorrhage. Variable retained placenta has the highest risk for postpartum hemorrhage, continued parity, preeclampsia, and cesarean section. Caesarean section and preeclampsia variables are protective factors.
Differences In Serum IL-6 Levels Between First-Trimester Normal Pregnancy and Spontaneous Abortion Vella Amalia; Utama, Bobby Indra; Dessy Arisanty; Nelmi Silvia
Andalas Obstetrics And Gynecology Journal Vol. 9 No. 1 (2025)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.9.1.115-123.2025

Abstract

Objectives: In spontaneous abortion cases without previously known predisposing factors, an increase proinflammatory cytokines, especially interleukin 6 (IL-6), found in local and systemic specimens compared to normal 1st -trimester pregnancies. Therefore, IL-6 is thought to have a role in implantation failure in early pregnancy resulting in spontaneous abortion. However, research on serum IL-6 levels in spontaneous abortion patients is still limited in Indonesia. This study aims to determine the difference in serum IL-6 levels in normal pregnancy 1 st - trimester and spontaneous abortion in hospitals in Padang City; Method: This study is an analytical study with a cross-sectional design using secondary data of 21 blood serum samples from each research group at the Biomedical Laboratory of FK Unand. Samples were collected using a consecutive sampling technique. A serum examination was performed with the ELISA technique. Bivariate data analysis using Mann-Whitney statistical test based on data type and distribution; Result: The results showed that the mean value of serum IL-6 levels was 280,56 ng/L in the normal pregnancy group in the 1st -trimester and the median value of the spontaneous abortion group was 279,78 ng/L. There was no significant difference in serum IL-6 levels in normal pregnancy in the 1st -trimester and spontaneous abortion (p = 0,980); Conclusion: This study concluded that there was no difference in serum IL-6 levels between patients with normal pregnancy in the 1st -trimester and spontaneous abortion in hospitals in Padang City. Keywords: Spontaneous abortion, first trimester, serum interleukin 6, cytokines, ELISA
Relationship Between Risk Factors and The Incidence of Gestational Trophoblastic Neoplasia at RSUP Dr. M. Djamil Padang Year 2019-2021 Almujahid, Aldi; Syamel Muhammad; Asterina
Andalas Obstetrics And Gynecology Journal Vol. 8 No. 2 (2024)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.8.2.746-753.2024

Abstract

Background : Gestational Trophoblastic Neoplasia (GTN) is a tumor originating from cytotrophoblast and syncytotrophoblast that invades myometrium, damages surrounding tissue and blood vessels, and causing bleeding. Purpose : This study aims to determine the relationship between age, history of previous pregnancies, β-hCG levels, parity, and interval with last pregnancy on the incidence of GTN. Method : This research is an observational analytic study with a cross sectional research design. Univariate analysis was carried out which described the frequency distribution of variables and bivariate analysis with the chi square statistical test . Result : The results of this study showed that there was a significant relationship between age, history of previous pregnancies, β-hCG levels and parity) and the incidence of GTN, while the interval with the last pregnancy did not have a significant relationship with the incidence of GTN . Conclusion: It was concluded that age, history of previous pregnancy, β-hCG levels, and parity are risk factors for GTN.
Efficacy of EMCO Therapy on Serum β-hCG Levels in Case of Gestational Trophoblastic Neoplasm (GTN) at Dr. M. Djamil Hospital Padang 2019-2021 Siregar, Attahhal Fikrian Syadiq; Syamel Muhammad; Elly Usman
Andalas Obstetrics And Gynecology Journal Vol. 8 No. 2 (2024)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.8.2.754-762.2024

Abstract

Backgrounds: Etoposide, Methotrexate, Cyclophosphamide, and Vincristine (EMCO) Chemotherapy is used as an alternative therapy for patients with a diagnosis of Gestational Trophoblastic Neoplasm (GTN) at Dr. M. Djamil Hospital Padang because Actinomycin D has not been included in the National Formulation (FORNAS). Purpose: To determine the efficacy of EMCO therapy with limited Actinomycin D on serum β-hCG levels in Gestational Trophoblastic Neoplasm (GTN) cases at Dr. M. Djamil Padang Hospital in 2019-2021. Methods: The type of research used is numerical comparative analytics with a cross sectional approach. The number of samples was 17 GTN patients who had done EMCO chemotherapy and checked β-hCG levels before and after chemotherapy. The research was conducted from April to October 2022 at Dr. M. Djamil Hospital Padang. Data processing using total sampling technique and tested using Wilcoxon Test. Results: Most GTN patients were found to be <40 years old (64,7%), history of molar hydatidiform pregnancy (47,1%), last pregnancy interval <4 months (58,8%), β-hCG level before chemotherapy ranged from 104-105 mIU/mL (52,9%), tumor size >5 cm (58,8%), metastasis location in the internal genital tract (35,5%), and patients who did not have metastasis (52,9%). Conclusion: There was a significant decrease in β-hCG levels after chemotherapy using EMCO for three cycles in patients with a diagnosis of GTN.
High Grade Appendiceal Mucinous Neoplasma Reviewing Primary Tube Malignancy : A Case Report Kurnia, Irfan; Antonius, Puja Agung; Muhammad, Syammel
Andalas Obstetrics And Gynecology Journal Vol. 7 No. 2 (2023)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.7.2.467-472.2023

Abstract

Appendiceal mucinous neoplasms (AMNs) are rare tumors accounting for less than 1% of all cancers. The clinical presentations of AMN vary significantly and the diagnosis of most patients is during surgery for suspected appendicitis, peritonitis or gynecological cancer. There were many case reports AMN mimicking an ovarian cancer. In this case, we reported a 64-year postmenopause woman with diagnosed peritonum carcinomatosis dd/ ovarian cancer and it actually AMN in RSUP dr. M. Djamil Padang, West Sumatera. The diagnosis is estimated by ultrasonography (USG), computed tomography (CT), magnetic resonance imaging (MRI) and diagnostic laparoscopy followed by histopathologic verification. The evaluation of the prognosis of appendix mucinous adenocarcinoma mainly depends on whether the tumour is in an advanced stage, the degree of malignancy, and whether an AMN is formed
Description of Post Anesthetic Shivering (PAS) in Post Spinal Anesthesia Caesarean Section Rafifa, Tuffahati Naura; Rinal Effendi; Aladin
Andalas Obstetrics And Gynecology Journal Vol. 8 No. 2 (2024)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.8.2.763-774.2024

Abstract

Background: Post anaesthetic shivering (PAS) is a fasciculation of the face, jaw, or head or the occurrence of muscle hyperactivity so that the body can produce heat after anesthesia. Multiple factors can influence the incidence of PAS including age, sex, ASA physical status, body mass index, type of anesthesia, duration of surgery, room temperature, preoperative body temperature (<36,5⁰C), and type of surgery.  Objective : The purpose of this study was to describe the incidence of PAS in post-spinal anesthesia caesarean section patients at RSIA Siti Hawa Padang Method: This research is a descriptive observational study using accidental sampling technique and obtained a total sample of 52 patients Result: The result showed that 25 of 52 patients (48,1%) experienced PAS. Most PAS events were experienced by moderate grade (25%), the age group >35 years (60%), underweight body mass index (62,5%), ASA II status (52,2%), preoperative temperature in the hypothermia group (51,4%), postoperative temperature in the normothermia group (66,7%), and operation duration >30 minutes (57,1%) Conclusion: Most of the patients did not experience PAS and most of PAS experience was moderate grade.
What to Expect in Primigravidae Adolescent Pregnancy with Malaria in Remote Area: A Case Report Murtani, Christian; Fiona Valerie Muskananfola; Jeffren Evander Bulan
Andalas Obstetrics And Gynecology Journal Vol. 8 No. 2 (2024)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.8.2.786-791.2024

Abstract

Background: Malaria is an infection transmitted by parasite-infected Anopheles mosquito. Pregnancy is one of the risk factors for infection and worse prognosisCase: Here we present a case of primigravidae adolescent pregnancy with malaria in a remote area. Patient presented with fever 10 days prior. Laboratory work-up showed microcytic hypochromic anemia, grade III thrombocytopenia, positive P. falciparum, and IUFD as disease outcome. The most common malaria-related hematological consequences are anemia and thrombocytopenia. Anemia in malaria is caused by the obligatory destruction of erythrocytes during the acute phase and might be related to bone marrow dyserythropoiesis. Several theories suggest mechanisms of thrombocytopenia in P. falciparum malaria such as increased platelet aggregation, bone marrow alteration, microvascular sequestration, and endothelial activation. Intrauterine Fetal Death (IUFD) might be related to microvasculature blockage or inflammation by the infected erythrocyte (IE). Inflammation in the intervillous regions of the placenta results in placental malaria (PM). PM may cause intrauterine growth restriction, premature delivery, and low birth weight, thus increasing newborn mortality.Conclusion: Malaria in pregnancy has a devastating impact on both mother and fetus. Patient’s characteristics and background greatly influence malaria outcomes and treatment continuity. Holistic treatment is recommended to enhance patient prognosis and health-seeking behavior
Collaborative Intervention Assistance Model In An Effort To Increase The Quality Of Pregnant Women Services To Reduce Maternal Mortality In Padang City Adnani, Syahredi; Rizanda Machmud; Dwiana Ocviyanti
Andalas Obstetrics And Gynecology Journal Vol. 8 No. 2 (2024)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.8.2.667-674.2024

Abstract

Background : Maternal death, as defined by WHO, includes deaths during pregnancy or within 42 days postpartum due to pregnancy-related causes. The Maternal Mortality Rate (MMR) quantifies maternal deaths per 100,000 live births. A key target of the Millennium Development Goals (MDGs) was reducing the MMR by three-quarters between 1990 and 2015, aiming for a global rate under 70 per 100,000 by 2030. In Indonesia, the 2012 Demographic and Health Survey reported an MMR of 359 per 100,000 live births, with West Sumatra at 212 per 100,000. Objective : This study employs a mixed-method approach, focusing on pregnant women visiting health centers in Padang City, to assess an intervention model. Result : Maternal mortality in Indonesia is mainly caused by bleeding, eclampsia, and infections, with contributing factors including delayed care access, socio-cultural, educational, and economic challenges. Significant health issues include hypertensive disorders, diabetes, acute kidney injury, jaundice, and thyroid disease. Low educational and economic levels in rural areas correlate with higher maternal morbidity and mortality. Government efforts, such as the Maternity Guarantee (Jampersal) and the Maternal and Child Health (KIA) Handbook, aim to improve maternal health but face challenges due to poor resource utilization. Conclusion : Indonesia struggles to meet maternal mortality reduction targets, with rates high compared to other Asian countries. Effective interventions must address both direct and indirect causes of maternal deaths, improve education and economic conditions, and enhance healthcare access. Government programs show promise but require better implementation and community engagement to reduce maternal mortality rates effectively.

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