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Bali Dermatology and Venereology Journal
Published by Universitas Udayana
ISSN : 26225417     EISSN : 2715694X     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology
Bali Journal of dermatology and venereology is published by Department of dermatology and venereology, Udayana University, Bali, Indonesia. Bali Journal of dermatology and venereology is an open access, peer reviewed journal aiming to communicate high quality research articles, reviews and general articles in the field of dermatology and venereology. Bali Journal of dermatology and venereology publishers articles which encompass all aspects of basic research/clinical studies related to the field of dermatology and venereology and allied science fileds. The Journal aims to bridge and integrate the intellectual, methodological, and substantive diversity of medical scholarship, and to encourage a vigorous dialogue between medical scholars and practitioners. The Journal welcomes contributions which promote the exchange of ideas and rational discourse between practicing educators and medical researchers all over the world.
Arjuna Subject : Kedokteran - Dematologi
Articles 80 Documents
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A retrospective study of condyloma acuminata profile in outpatient clinic of dermato-venereology Sanglah General Hospital Denpasar, Bali-Indonesia period 2015-2017 Ni Made Dwi Puspawati; Sissy Sissy; Dewi Gotama
Bali Dermatology and Venereology Journal Vol. 1 No. 1 (2018)
Publisher : DiscoverSys Inc

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/bdv.v1i1.1

Abstract

Introduction: Condylomata acuminata (CA) is human papillomavirus (HPV) infection, and one of the most common sexually transmitted disease, characterized with papul or papillomatous nodule in genital, perineum and anal, this disease can be asymptomatic as well. Some study proved sexually transmitted infection increases the incidence of Human immunodeficiency virus (HIV)/ acquired immunodeficiency syndrome (AIDS), and vice versa. Management of CA is Trichloroacetic acid (TCA), Tincture Podophyllin, and Electrocautery. This study aims to determine profile of condyloma acuminata in Dermatovenereology Outpatient Polyclinic Sanglah General Hospital Denpasar Bali period 2015-2017. A retrospective study during three years (2015-2017).Method: Data was obtained from medical record in Dermatovenereology Outpatient Polyclinic Sanglah General Hospital Denpasar Bali period 2015- 2017.Result: Total patient condyloma acuminata is 260 patients (5.48%), male is dominant 70 patients (67.31%), range age 12-35 years old (123%), there was 59 patient who infected with HIV (22.31%), with five pregnancy (1.92%). Most therapy is given trichloroacetic acid (TCA) (79.62%).Conclusion: Men suffered from condyloma acuminata more commonly than women, the most common treatment for this condition is trichloroacetic acid (TCA) 
Profile of pyoderma in dermatology outpatient departement at Sanglah General Hospital Denpasar, Bali-Indonesia period January 2016 until December 2017 Ni Luh Putu Ratih Vibriyanti Karna; Dewi Gotama; Sissy Sissy
Bali Dermatology and Venereology Journal Vol. 1 No. 1 (2018)
Publisher : DiscoverSys Inc

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/bdv.v1i1.2

Abstract

Introduction: Pyodermas are infections in the epidermis, just below the stratum corneum or in hair follicles. It is most common in children, although it can also affect adults. Pyoderma often found in tropic areas. Pyoderma is caused by Staphylococcus, Streptococcus, or both. This study aimed to identify the profile of pyoderma in Dermatology Outpatient Department at Sanglah General Hospital Denpasar Periods January 2016 – December 2017.Method: Study design using descriptive retrospective model, done by taking data from daily visit record in Dermatology Outpatient Department at Sanglah General Hospital Denpasar Periods January 2016 – December 2017.Result: Pyodermas is one of the common skin problems observed in patients attending dermatology OPD. The number of new cases in pyoderma is 202 cases (7,32%), often found in males and 0-5 years age group (35,64%). The diagnosis of furuncle is the most finding type of pyoderma and the most commonly given therapy is a combination therapy of systemic antibiotics with topical. Co-amoxiclav is the most common drug that uses orally and fusidic acid as topical ointment.Conclusion: pyoderma remains as the most common skin infection in dermatology outpatient department at Sanglah General Hospital, Bali-Indonesia.
Necrotic lower extremities ulcers caused by calciphylaxis in chronic renal failure patient Nyoman Suryawati; Herman Saputra
Bali Dermatology and Venereology Journal Vol. 1 No. 1 (2018)
Publisher : DiscoverSys Inc

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/bdv.v1i1.3

Abstract

Introduction: Lower extremity ulcers often create diagnostic challenges and influence patient morbidity and mortality. The most common causes are venous insufficiency, arterial insufficiency, and neuropathic. Ulcers associated with systemic condition often face diagnostic and therapeutic challenge. We report a necrotic lower extremity ulcer caused by calciphylaxis in a patient with chronic renal failure. Case: We reported a 48-year-old Javanese woman, complained of painful lower extremities ulcers since 1.5 months ago. The patient had a history of renal failure and hypertension, undergone routine hemodialysis since 13 years ago, and used Continuous Ambulatory Peritoneal Dialysis (CAPD) since one year ago. Dermatology status on dorsum pedis sinister as well as cruris dexter and sinister showed multiple ulcers on livid skin covered by black eschar, accompanied by tenderness. Laboratory results showed anemia (Hb 7.6), hypoalbuminemia (2.7), increased serum urea level (170.4 mg/dl), increased serum creatinine (11.23 mg/dl), increased calcium (10.4 mg/dl), high inorganic phosphorus (8.5 mg/dl) and high parathyroid hormone (2,164). BOF examination showed abdominal calcification, while radiographic examination on cruris dexter et sinister showed soft tissue calcification and osteoporosis. Histopathology result supported the presence of calciphylaxis. The patient was diagnosed with stage V chronic renal failure, hypertension, and calciphylaxis caused by secondary hyperparathyroidism. She was managed by low calcium and phosphate diet, lanthanum, paracetamol, folic acid, adalat oros, captopril and wound debridement. Conclusion: Calciphylaxis is a rare phenomenon of cutaneous necrosis associated with end-stage renal disease. Control of end-stage renal disease may be an important factor for treatment of calciphylaxis and patient with calciphylaxis usually had a poor prognosis.Keywords: necrotic lower extremity ulcer, chronic renal failure, calciphylaxis
Interaction between leprosy and HIV infection Prima Sudarsa; Ratih Vibriyanti Karna; Luh Mas Rusyati
Bali Dermatology and Venereology Journal Vol. 1 No. 1 (2018)
Publisher : DiscoverSys Inc

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/bdv.v1i1.4

Abstract

Introduction: Leprosy and Human Immunodeficiency Virus (HIV) infections still count as major health issues worldwide. Starting with the HIV pandemic back in the eighties, leprosy was feared to re-emerge as the HIV cases arose. Co-infections between leprosy and HIV were worried to cause an increase in leprosy cases, with worse clinical manifestation, predominantly toward the lepromatous spectrum, decrease in therapy response, and prolonged therapy period. Unlike its interaction with tuberculosis, HIV infection was turned out to not increasing nor deteriorating the manifestation of leprosy infection. All clinical spectrum of leprosy was found in HIV infection patients without predomination of lepromatous type. Responses to leprosy Multi-Drug Therapy (MDT) regimen were also found similar between leprosy patients with or without HIV.Conclusion: It is recommended to treat co-infective patients both with leprosy MDT and antiretroviral therapy. Manifestation of leprosy as a part of immune reconstitution syndrome need more attention and investigation.Keywords: HIV infection, leprosy, interaction
Profile of onychomycosis in dermatology outpatient department at Sanglah General Hospital Denpasar, Bali-Indonesia periods 2016-2017 IGAA Dwi Karmila; Adeline Santoso
Bali Dermatology and Venereology Journal Vol. 1 No. 1 (2018)
Publisher : DiscoverSys Inc

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/bdv.v1i1.5

Abstract

Introduction: Onychomycosis is a fungal infection of the nails that causes discoloration, thickening, and separation from the nail bed. Onychomycosis is caused by various organisms, most often dermatophytes of the genus Trichophyton. Other organisms include Candida, which is more common in fingernail infections and patients with chronic mucocutaneous candidiasis. Nondermatophyte molds are a less common cause in the general population. This study aimed to identify sex, age, classification, fungal culture, treatment, and incident of secondary infection in onychomycosis at Dermatology Outpatient Department at Sanglah General Hospital Denpasar Periods January 2016 – December 2017.Methods: Study design using descriptive retrospective model done by taking data from medical record in Dermatology Outpatient Department at Sanglah General Hospital Denpasar Periods 2016-2017.Result: There were 268 patients in Dermatovenereology Outpatient Department at Sanglah General Hospital Denpasar, 29 (10,82%) of whom were diagnosed with onychomycosis in Periods 2016-2017. According to age group, the most cases occur in 26-65 year age groups. Females were more frequently affected than males. The most classification finding is distal and lateral subungual onychomycosis and the most commonly isolated fungi were yeasts from the Candida species. The most commonly given therapy is a combination therapy of systemic antifungal with topical. Fluconazole is the most common drug that uses orally and ciclopirox as topical agent.Conclusions: Onychomycosis is one of the common fungal infection observed in patient attending dermatology outpatient department with the most classification finding is distal and lateral subungual onychomycosis. The most commonly isolated fungi were Candida sp.Keywords: onychomycosis, fungal, nail
Bullous pemphigoid in 65 years old female: a case report I Dewa Made Rendy Sanjaya; Putu Artana; Embun Dini Hari
Bali Dermatology and Venereology Journal Vol. 1 No. 2 (2018)
Publisher : DiscoverSys Inc

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/bdv.v1i2.7

Abstract

Introduction: Bullous pemphigoid is an autoimmune disorder. The incidence of bullous pemphigoid has increased over time, current understanding regarding treatment and complication is an important issue considering the disease often occur in elderly resulting in high rates of morbidity to the patients. Aim of current case report is to describe the clinical relevance regarding symptom and treatment of bullous pemphigoid.Case presentation: A 65 years old female patient, came with chief complaints of bullae in abdominal region with itching and burning sensation in the ruptured bullae. Over time bullae spread in lower and upper extremity. Patient was admitted for four days with therapy intravenous steroids, oral antihistamine, and potent topical steroids. Patient was discharged from hospital in well condition.Conclusion: Bullous pemphigoid is an inflammatory autoimmune skin disease and usually result in good prognosis with adequate management.Keywords: autoimmune, bullous, pemphigoid, skin, disease. 
The high homeostatic model assessment of insulin resistance as risk factor for acne vulgaris I Gusti Ayu Agung Praharsini; Anak Agung Gde Putra Wiraguna; Stefani Nurhadi
Bali Dermatology and Venereology Journal Vol. 1 No. 2 (2018)
Publisher : DiscoverSys Inc

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/bdv.v1i2.8

Abstract

Background: Acne vulgaris (AV) is a common chronic skin disease involving blockage and or inflammation of pilosebaceous glands which usually affects teenagers and young adults. Elevated sebaceous gland secretion, Propionibacterium acne colonization and inflammation, high androgen effects, and follicular hyperproliferation are the main pathogenic factors of AV. IGF-1 and insulin were studied to stimulate sebaceous lipogenesis. In the skin, besides inducing lipid production in human sebocytes IGF-1 also induces keratinocyte proliferation in vitro and in vivo. HOMA-IR is an examination to determine insulin activity in the basal state.Objective: To prove that high HOMA-IR value is a risk factor for the occurrence of acne vulgaris.Methods: This study is a case control analytic study by comparing HOMA-IR in subjects with AV (case group) and non AV (control group). AV is diagnosed based on clinical predilection. Insulin testing was carried out by the immulite 2000 device through the immunochemiluminescent method.Results: Mean HOMA-IR of case group is 2.63 ± 0.29 meanwhile in the control group was 1.71 ± 0.26 (p <0.001). Subjects with high HOMA-IR had 4.8 times higher risk to experience AV compared to patients with normal HOMA-IR values (p <0.001; 95% IK 2,765-8,332). Conclusion: HOMA-IR values in acne patients were higher than controls. A high HOMA-IR value is an AV risk factor.
Positive correlation between psoriasis vulgaris severity degree with HbA1C level Made Swastika Adiguna; Made Wardhana; Fresa Nathania Rahardjo
Bali Dermatology and Venereology Journal Vol. 1 No. 2 (2018)
Publisher : DiscoverSys Inc

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/bdv.v1i2.11

Abstract

Introduction: Psoriasis is a skin abnormality based on chronic inflammation immune mediated. Inflammatory mediator roles (Th-1, TNF-α, IL-6,IL-7, IL-8, IL-17, and IL-23) in its pathogenesis proven to inhibit insulin receptor and glucose uptake from fat tissue and causing insulin resistance, then blood glucose level increased. Mean blood glucose level within 3 months can be represented by HbA1c (glycosylated haemoglobin) level. HbA1c is a bond between glucose and hemoglobin.           Objective: The aim of this study is to understanding correlation between psoriasis vulgaris severity degree with HbA1c.Material and methods: This study is using cross sectional method. HbA1c level examination done by drawing venous blood, then analyzed with chromatography method. Samples were selected by using inclusion and exclusion criteria and consecutive sampling method.Result: Study result shows subject consist of total 51 subjects consists of 33 subjects with psoriasis vulgaris (22 males and 11 females with youngest age of 15 and oldest age of 65 years old), and 18 subjects without psoriasis vulgaris. Psoriasis vulgaris severity degree measured with Psoriasis Area Severity Index (PASI), then grouped to 3 categories: mild PASI score <6, moderate PASI score  6 – 12, and severe PASI score> 12. Mostly  (15 subjects) including mild category. HbA1c level on this study subjects resulted minimum level of 4.6%, maximum 12.1 %, and median 5.4%.  Based on Perkeni consensus, normal HbA1c level is <5,7%, prediabetes 5,7-6,4%, and diabetes >6,5%. HbA1c level of psoriasis vulgaris subjects are higher than non psoriasis vulgaris subjects significantly (p=0,019). Psoriasis vulgaris causing increase of HbA1c level with Prevalence Ratio (PR) 6,55. Thus, Psoriasis vulgaris subjects have increased risk 6,5 times to increase HbA1c level compared with non psoriasis vulgaris subjects. Correlation between severity degree and HbA1c level found in positive course significantly with moderate strength of correlation (Spearman correlation; r = 0.580, p<0,001).Conclusion: HbA1c level on psoriasis vulgaris subjects are higher than non psoriasis vulgaris, and psoriasis vulgaris severity degree positively correlated with HbA1c increasing level. Every increase of  psoriasis vulgaris severity degree will cause increase level of  HbA1c.
Low plasma level of insulin-like growth factor-I (IGF-I) is a risk factor for multibacillary type of leprosy Luh Mas Rusyati; Made Swastika Adiguna; Indra Teguh Wiryo
Bali Dermatology and Venereology Journal Vol. 1 No. 2 (2018)
Publisher : DiscoverSys Inc

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/bdv.v1i2.12

Abstract

Introduction: Leprosy is one of infectious diseases with complex issues. Previous study showed poverty, malnutrition, lack of proper food and nutrient intake, as well as low income. Recently, many studies reported insulin-like growth factor-I (IGF-I) as excellent nutrient marker.Objective: This study aims to prove that low plasma level of insulin-like growth factor-I is a risk factor for multibacillary type of leprosy. Material and methods: This case-control study design involved 38 patients with leprosy subjects as cases and 38 control subjects. The sample collection is done by consecutive sampling and has fulfilled the inclusion and exclusion criteria which matched by age and gender in Dermatology and Venereology Outpatient clinic of Sanglah General Hosptital. The collected data was analyzed using SPSS version 23.0 with Pearson Chi square test to obtain Odds Ratio. Results: This study showed that IGF-I plasma levels in the case group were significantly lower than the control group (p<0.05) with Odds ratio for IGF-I plasma 34.61 (95% CI= 7.17-167.01, p<0.001)Conclusion: Low plasma level of insulin-like growth factor-I is a risk factor for multibacillary type of leprosy.
Bacterial vaginosis as a risk factor of preterm premature rupture of membrane (PPROM) Aanak Agung Gde Putra Wiraguna; Luh Made Mas Rusyati; I Dewa Ayu Vanessa Vijayamurthy
Bali Dermatology and Venereology Journal Vol. 1 No. 2 (2018)
Publisher : DiscoverSys Inc

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/bdv.v1i2.13

Abstract

Introduction: The pathogenesis of PPROM is complex and not fully understood. Recent studies showed that such role of genital tract infection as bacterial vaginosis in the pathogenesis of PPROM turned out to be present. They produce lipase enzymes in which they can form compounds with the fibrous tissue of amniotic membrane resulting in increased risk of rupture of the membrane.Objective This study aims to prove that bacterial vaginosis is a risk factor for preterm premature rupture of membrane.Material and methods: This research used case control method. Sampling was using the consecutive sampling method and had fulfilled inclusion and exclusion criteria with age-based matching, then vaginal swab sampling was conducted, painted with gram staining in the Dermalotogy and Venereology Laboratory of Sanglah Hospital, and Nugent score.Result: Total of 76 pregnant women with 24-36 weeks of gestation were investigated, 38 mothers with PPROM and 38 mothers with normal pregnancy. Average score of Nugent at preterm PROM was 7.18 and in normal pregnancy was 2.37. Bacterial vaginosis risking for PPROM 7 times (OR= 7.0, 95% CI= 1.21-17.68, p= 0.001).Conclusion: Bacterial vaginosis as a risk factor for the occurrence of PPROM.

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