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All Journal Medicina E-Jurnal Medika Udayana Berkala Ilmu Kesehatan Kulit dan Kelamin ISM (Intisari Sains Medis) : Jurnal Kedokteran Bali Dermatology and Venereology Journal
I Gusti Ayu Agung Dwi Karmila
Departemen Dermatologi Dan Venereologi FK Udayana / RSUP Prof. Dr. IGNG Ngoerah Denpasar, Bali, Indonesia
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Profile of onychomycosis in dermatology outpatient department at Sanglah General Hospital Denpasar, Bali-Indonesia periods 2016-2017 Karmila, IGAA Dwi; Santoso, Adeline
Bali Dermatology and Venereology Journal Vol 1, No 1 (2018)
Publisher : DiscoverSys Inc

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (192.215 KB) | DOI: 10.15562/bdv.v1i1.5

Abstract

Introduction: Onychomycosis is a fungal infection of the nails that causes discoloration, thickening, and separation from the nail bed. Onychomycosis is caused by various organisms, most often dermatophytes of the genus Trichophyton. Other organisms include Candida, which is more common in fingernail infections and patients with chronic mucocutaneous candidiasis. Nondermatophyte molds are a less common cause in the general population. This study aimed to identify sex, age, classification, fungal culture, treatment, and incident of secondary infection in onychomycosis at Dermatology Outpatient Department at Sanglah General Hospital Denpasar Periods January 2016 – December 2017.Methods: Study design using descriptive retrospective model done by taking data from medical record in Dermatology Outpatient Department at Sanglah General Hospital Denpasar Periods 2016-2017.Result: There were 268 patients in Dermatovenereology Outpatient Department at Sanglah General Hospital Denpasar, 29 (10,82%) of whom were diagnosed with onychomycosis in Periods 2016-2017. According to age group, the most cases occur in 26-65 year age groups. Females were more frequently affected than males. The most classification finding is distal and lateral subungual onychomycosis and the most commonly isolated fungi were yeasts from the Candida species. The most commonly given therapy is a combination therapy of systemic antifungal with topical. Fluconazole is the most common drug that uses orally and ciclopirox as topical agent.Conclusions: Onychomycosis is one of the common fungal infection observed in patient attending dermatology outpatient department with the most classification finding is distal and lateral subungual onychomycosis. The most commonly isolated fungi were Candida sp.Keywords: onychomycosis, fungal, nail
SUBACUTE CUTANEOUS LUPUS ERYTHEMATOSUS PADA PENDERITA LUPUS ERITEMATOSUS SISTEMIK Widiawati, Sayu; Karmila, IGAA. Dwi
Medicina Vol 46 No 2 (2015): Mei 2015
Publisher : Medicina

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (225.018 KB)

Abstract

Lupus eritematosus (LE) merupakan penyakit autoimun dengan variasi klinis luas dari manifestasiterbatas pada kulit hingga sistemik. Cutaneous lupus erythematosus yang spesifik dibedakan menjadiacute cutaneous lupus eryhtematosus, subacute cutaneous lupus eryhematosus (SCLE), dan discoid lupuserythematosus. Deteksi dini penyakit masih merupakan tantangan, karena LE dikenal sebagai “thegreat imitators”. Kasus, perempuan, usia 8 tahun dengan riwayat bercak merah pada wajah, danpunggung, disertai demam berulang. Lesi kulit berupa makula dan papul yang berkembang menjadilesi papuloskuamosa dan beberapa lesi anular. Pemeriksaan histopatologi menunjukkan pola reaksilikenoid sesuai SCLE. Pada kasus juga memenuhi kriteria sebagai lupus eritematosus sistemik.Penatalaksanaan meliputi terapi definitif berupa kortikosteroid sistemik dan topikal, terapi suportif,simtomatis, dan pada kasus didapatkan respon terapi yang baik. [MEDICINA 2015;46:130-4].Lupus erythematosus (LE) is an autoimmune disease that has wide range clinical variation, fromlimited to the skin until systemic manifestation.There are three form of spesific cutaneous lupuserythematosus; acute cutaneous lupus eryhtematosus, subacute cutaneous lupus eryhematosus (SCLE),and discoid lupus erythematosus. Early detection of LE is still challenging consider LE known as”thegreat imitators”. Case, 8 years old girl, with a red patch on her face, back and extremities, accompaniedby recurring fever. Skin lesion present as erythematous maculae and papule, that evolve intopapulosquamous lesion and few with anular shape. Histopathology examination show lichenoid reactionreveal SCLE. The patient also meet the ACR’s criteria for the classification of SLE. Therapy givenweredefinitive therapy including systemic and topical corticosteroid, suportif and symptomatic therapyalso. The case show good response to these therapy. [MEDICINA 2015;46:130-4].
Dermoscopy in superficial fungal infection Sawitri, Putu Dyah; Karmila, I Gusti Ayu Agung Dwi; Sadeli, Marrietta Sugiarti
Bali Dermatology and Venereology Journal Vol 4, No 2 (2021)
Publisher : DiscoverSys Inc

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/bdv.v4i2.52

Abstract

 Superficial fungal infections are one of the most common skin infection infections. It is caused by fungal pathogens and are limited to the outer layer of the skin, hair, and nails. Superficial fungal infections include dermatophytosis, superficial candidiasis, and diseases caused by Malassezia spp. Most physicians diagnose and treat superficial fungal infections based solely on clinical appearance. But unfortunately, there are many other infectious and non-infectious diseases that have similar clinical appearance.Dermoscopy is a practical and noninvasive imaging method that allows magnifying clinical surface images that are normally invisible under a magnifying lens. In diagnosing superficial mycosis, dermoscopy was found to have a higher sensitivity and specifity compared to pottasium chloride (KOH) and fungal culture.More understanding is needed about the use of dermoscopy in diagnosing superficial fungal infections in the hope of being able to provide an overview of superficial fungal infections and dermoscopy, as well as dermoscopy features in some superficial fungal infections. In this article, the author describe dermoscopic findings in various superficial fungal infections on the skin, hair, and nails.
PREVALENSI DAN PROFIL HERPES ZOSTER DI RUMAH SAKIT UMUM PUSAT SANGLAH DENPASAR PERIODE APRIL 2015 SAMPAI MARET 2016 Rania Ayu Permata Putri Kornia; I Gusti Ayu Agung Dwi Karmila
E-Jurnal Medika Udayana Vol 9 No 8 (2020): Vol 9 No 08(2020): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

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Abstract

Herpes zoster atau yang juga sering disebut shingles merupakan penyakit yang disebabkan reaktivasi virus varisela zoster laten di akar sensoris dorsal atau ganglia saraf kranialis, dan biasanya bermanifestasi sebagai ruam vesikuler yang nyeri di sepanjang distribusi dermatom. Beberapa faktor risiko terjadinya herpes zoster adalah usia tua, orang yang imunokompromais, dan jenis kelamin wanita. Tujuan dari penelitian ini adalah untuk mengetahui prevalensi dan profil herpes zoster di RSUP Sanglah Denpasar periode April 2015 sampai Maret 2016. Penelitian ini bersifat deskriptif retrospektif. Sampel penelitian ini adalah seluruh pasien yang terdiagnosis herpes zoster pada rekam medis di Rumah Sakit Umum Pusat Sanglah Denpasar periode April 2015 sampai Maret 2016. Data penelitian diambil dari rekam medis di RSUP Sanglah Denpasar periode April 2015 sampai Maret 2016. Hasil penelitian didapatkan prevalensi herpes zoster di RSUP Sanglah Denpasar periode April 2015 sampai Maret 2016 sebanyak 28 penderita. Laki-laki 60,7% dan perempuan 39,3%, usia terbanyak adalah 45-64 tahun (50%), pekerjaan terbanyak adalah pekerja swasta dan ibu rumah tangga (masing-masing 21,4%), lokasi lesi tersering adalah torakalis (32,1%), penyakit penyerta terbanyak adalah DM dan hipertensi (masing-masing 10,7%), komplikasi terbanyak adalah PHN (14,3%), antivirus yang paling banyak diberikan adalah asiklovir (82,1%), dan lebih banyak penderita yang diberikan pengobatan antivirus lebih dari 72 jam sejak munculnya gejala (57,1%). Dapat disimpulkan bahwa kejadian herpes zoster masih banyak terjadi di masyarakat dan cenderung meningkat. Kata Kunci: herpes zoster, prevalensi, profil
PROPORSI DAN KARAKTERISTIK AKNE VULGARIS PADA MAHASISWA PROGRAM STUDI SARJANA KEDOKTERAN DAN PROFESI DOKTER FAKULTAS KEDOKTERAN UNIVERSITAS UDAYANA TAHUN 2019 Joanne Roxanne; I Gusti Ayu Agung Elis Indira; Made Swastika Adiguna; I Gusti Ayu Agung Dwi Karmila
E-Jurnal Medika Udayana Vol 10 No 4 (2021): Vol 10 No 04(2021): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2021.V10.i4.P15

Abstract

ABSTRAK Latar Belakang: Akne vulgaris (AV) merupakan penyakit yang umum terjadi pada remaja dan merupakan penyakit multifaktorial. Tujuan: Penelitian ini bertujuan untuk mengetahui proporsi dan karakteristik (jenis, distribusi, dan klasifikasi tingkat keparahan) serta beberapa faktor pencetus yang menyertai kejadian AV pada mahasiswa kedokteran yang sebagian besar dalam usia remaja Metode: Penelitian ini merupakan penelitian potong lintang deskriptif. Pengambilan data dilakukan dengan menggunakan formulir pengambilan data dilanjutkan dengan pemeriksaan lesi oleh peneliti. Hasil: Terdapat 87 (70,2%) dari 124 peserta penelitian yang terdiagnosis AV pada Mahasiswa Program Studi Sarjana Kedokteran dan Pendidikan Dokter Fakultas Kedokteran Universitas Udayana tahun 2019. Laki-laki lebih banyak mengalami AV (51,7%) dibandingkan perempuan (48,7%). Jenis lesi yang paling banyak ditemukan adalah komedo dengan tingkat klasifikasi ringan dan distribusi lesi paling banyak pada wajah. Komplikasi yang paling banyak terjadi adalah hiperpigmentasi. Diagnosis AV lebih banyak ditegakan pada subjek yang tidak memiliki riwayat keluarga, jarang membersihkan wajah (<3 kali sehari). Tercatat penggunaan masker bahan alami dalam penanganan AV yaitu spirulina, tomat, madu dan teh hijau Kata Kunci: Akne vulgaris, Proporsi, Karakteristik, Faktor Pencetus
Profile of onychomycosis in dermatology outpatient department at Sanglah General Hospital Denpasar, Bali-Indonesia periods 2016-2017 IGAA Dwi Karmila; Adeline Santoso
Bali Dermatology and Venereology Journal Vol. 1 No. 1 (2018)
Publisher : DiscoverSys Inc

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/bdv.v1i1.5

Abstract

Introduction: Onychomycosis is a fungal infection of the nails that causes discoloration, thickening, and separation from the nail bed. Onychomycosis is caused by various organisms, most often dermatophytes of the genus Trichophyton. Other organisms include Candida, which is more common in fingernail infections and patients with chronic mucocutaneous candidiasis. Nondermatophyte molds are a less common cause in the general population. This study aimed to identify sex, age, classification, fungal culture, treatment, and incident of secondary infection in onychomycosis at Dermatology Outpatient Department at Sanglah General Hospital Denpasar Periods January 2016 – December 2017.Methods: Study design using descriptive retrospective model done by taking data from medical record in Dermatology Outpatient Department at Sanglah General Hospital Denpasar Periods 2016-2017.Result: There were 268 patients in Dermatovenereology Outpatient Department at Sanglah General Hospital Denpasar, 29 (10,82%) of whom were diagnosed with onychomycosis in Periods 2016-2017. According to age group, the most cases occur in 26-65 year age groups. Females were more frequently affected than males. The most classification finding is distal and lateral subungual onychomycosis and the most commonly isolated fungi were yeasts from the Candida species. The most commonly given therapy is a combination therapy of systemic antifungal with topical. Fluconazole is the most common drug that uses orally and ciclopirox as topical agent.Conclusions: Onychomycosis is one of the common fungal infection observed in patient attending dermatology outpatient department with the most classification finding is distal and lateral subungual onychomycosis. The most commonly isolated fungi were Candida sp.Keywords: onychomycosis, fungal, nail
Dermoscopy in superficial fungal infection Putu Dyah Sawitri; I Gusti Ayu Agung Dwi Karmila; Marrietta Sugiarti Sadeli
Bali Dermatology and Venereology Journal Vol. 4 No. 2 (2021)
Publisher : DiscoverSys Inc

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/bdv.v4i2.52

Abstract

 Superficial fungal infections are one of the most common skin infection infections. It is caused by fungal pathogens and are limited to the outer layer of the skin, hair, and nails. Superficial fungal infections include dermatophytosis, superficial candidiasis, and diseases caused by Malassezia spp. Most physicians diagnose and treat superficial fungal infections based solely on clinical appearance. But unfortunately, there are many other infectious and non-infectious diseases that have similar clinical appearance.Dermoscopy is a practical and noninvasive imaging method that allows magnifying clinical surface images that are normally invisible under a magnifying lens. In diagnosing superficial mycosis, dermoscopy was found to have a higher sensitivity and specifity compared to pottasium chloride (KOH) and fungal culture.More understanding is needed about the use of dermoscopy in diagnosing superficial fungal infections in the hope of being able to provide an overview of superficial fungal infections and dermoscopy, as well as dermoscopy features in some superficial fungal infections. In this article, the author describe dermoscopic findings in various superficial fungal infections on the skin, hair, and nails.
Karakteristik kanker kulit di Rumah Sakit Umum Pusat Sanglah Denpasar tahun 2015-2018 Made Wardhana; I Gusti Nyoman Darmaputra; I Gde Nengah Adhilaksman; Nyoman Yoga Maya Pramita; Ricky Fernando Maharis; Made Dwi Puspawati; I Gusti Ayu Agung Dwi Karmila; I Gusti Agung Ayu Praharsini; I Gusti Ayu Agung Elis Indira; Nyoman Suryawati
Intisari Sains Medis Vol. 10 No. 1 (2019): (Available online 1 April 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (287.084 KB) | DOI: 10.15562/ism.v10i1.438

Abstract

Latar belakang: Prevalesi kanker kulit semakin meningkat di seluruh dunia. Walaupun insiden tertinggi pada kelompok berkulit putih, namun mengetahui epidemiologi dan tren penyakit dari kanker kulit diperlukan agar dapat menentukan pencegahan dan penanganan yang tepat.Tujuan: Untuk mengetahui karakteristik kanker kulit pada pasien yang telah dilakukan skin flap di Departemen Dermatologi dan Venereologi RSUP Sanglah.Metode: Penelitian ini merupakan studi deskriptif retrospektif dari catatan medis semua penderita kanker kulit yang memperoleh tindakan skin flap sejak Januari 2015 sampai dengan Desember 2019. Sampel diambil melalui total sampling. Karakteristik yang tercatat meliputi jenis kanker, jenis kelamin, umur, tipe kulit, pekerjaan, dan jenis flap yang dilakukan. Data yang terkumpul dianalisis secara deskriptif dengan program SPSS Ver21.Hasil: Terdapat 41 pasien kanker kulit yang memperoleh tindakan skin flap, terdiri dari 43,9% (n=16) BCC, 54,6% (n=10) melanoma, 21,9% (n=9) SCC, 9,8% (n=4) jenis kanker lain. Jenis flap yang umum digunakan yaitu simple advancement. Lokasi kanker paling umum ditemukan pada wajah dan kejadian kanker paling tinggi terjadi pada usia ≥50 tahun dan bekerja di luar ruangan.Simpulan: Kasus kanker tertinggi yaitu BCC dengan usia lebih dari 50 tahun dan bekerja di luar ruangan sebagai karakteristik paling umum pada semua kasus kanker.
Karakteristik Penderita Kusta Multi Basiller (MB) dengan Reaksi Erythema Nodosum Leprosum (ENL) di Poliklinik Kulit dan Kelamin RSUP Sanglah selama Tahun 2016-2018 Putu Ayu Saraswati; Luh Made Mas Rusyati; IGAA Dwi Karmila
Intisari Sains Medis Vol. 10 No. 3 (2019): (Available online: 1 December 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (199.944 KB) | DOI: 10.15562/ism.v10i3.477

Abstract

Introduction: Leprosy is still a burden on endemic countries such as Indonesia. As well as leprosy reaction is a problem associated with the cessation of treatment from leprosy patients. The purpose of this study was to do a description of the characteristics of leprosy patients with ENL reactions in the Skin and Sex Polyclinic of Sanglah Hospital Denpasar.Method: This study used a descriptive design with a retrospective approach conducted at the Skin and Sex Polyclinic of Sanglah General Hospital. A search related to the characteristics of leprosy patients who experienced an ENL reaction, then the data was presented in descriptive form.Results: Female gender tend to have more severe leprosy reactions (50%) compared to men. High income (50%), non-endemic area origin (44.8%), elementary school education level (44.4%), and active working (31.0%) tended to experience more severe leprosy reactions. And in this study more severe leprosy reactions were found in the multi-bacillary leprosy group (65.7%), whereas mild leprosy reactions were higher in the pauci-bacillary leprosy group (34.2%).Conclusion: The high rate of severe leprosy reaction requires special attention from both the government and health practitioners, so that there is an integrated management of leprosy, so that the population in Indonesia becomes healthier.
Skin flap pattern in skin cancer at Sanglah General Hospital Denpasar, Bali-Indonesia Made Wardhana; IGN Darmaputra; I Gde Nengah Adhilaksman Sunyamurti Wirawan; Nyoman Yoga Maya Pramita; Rikcy Fernando Maharis; Ni Made Dwi Puspawati; IGAA Dwi Karmila; IGAA Praharsini
Intisari Sains Medis Vol. 10 No. 3 (2019): (Available online: 1 December 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (917.309 KB) | DOI: 10.15562/ism.v10i3.518

Abstract

Background: The prevalence of skin cancer is consistently increasing recently, an hence a more comprehensive management is necessary for patients’ satisfaction. Generally, skin cancer is categorized into several histological types, including melanoma, basalioma, squamous cell carcinoma (SCC), and several other less common types such as keratoacanthoma, pyogenic granuloma, and Bechet disease. In dermatology, the intervention is limited which only consists of infiltrative anesthesia, no involvement of other organs, and no attachment to the underlying tissue. Therefore, random skin flap frequently becomes the preferred option that involves advancement, rotation, transposition, and interpolation flap. This study aims to investigate the profile of skin cancer and flap pattern among patients undergoing skin flaps procedure at Dermatology and Venereology Department of Sanglah General Hospital, Denpasar. Method: This study included all skin cancer patients who underwent skin flap surgery. Samples collection was performed retrospectively using patients’ medical records from January 2015 - December 2018. Results: Over the study period, there were a total of 41 skin cancer patients who underwent skin flap surgery of whom 10 (54.6%) patients were diagnosed with melanoma, 16 patients with basalioma, 9 patients with SCC and the remaining included 3 cases of acanthoma and 1 Bechet disease. Regarding the flap types, simple advancement and its variances were performed in 6 melanoma, 11 basaliomas, 5 SCC and 4 keratoacanthoma cases. Transposition flap was performed in 2 melanoma, 3 basalioma, and 3 SCC cases; whereas rotation flap was performed in 2 melanoma and 2 basaliomas and SCC cases.Conclusion: From 41 skin cancer patients discovered, basalioma was the most frequent cases and advancement techniques were the most frequently performed flap surgery. Only 1 post-surgical infection was found after rotational flap procedure.   
Co-Authors Adeline Santoso ajisma, Seva Anak Agung Gde Putra Wiraguna Aurelia Stephanie Henny Wijaya I Gde Nengah Adhilaksman I Gde Nengah Adhilaksman Sunyamurti Wirawan I Gusti Ayu Agung Elis Indira I Gusti Ayu Agung Praharsini I Gusti Ayu Agung Praharsisni I Gusti Nyoman Darmaputra I Ketut Agus Somia Indira, I Gusti Ayu Agung Elis Joanne Roxanne Ketut Kwartantaya Winaya Ketut Wida Komalasari Laksmi, Hermina Laksmi, I Gusti Ayu Agung Mini Luh Made Mas Rusyati Made Hermina Laksmi Made Martina Windari Made Sanitca Indah Made Swastika Adiguna Made Wardhana Marrietta Sugiarti Sadeli Natih, Sintha Aprillia Gita Nevristia Pratama Ni Luh Putu Ratih Vibriyanti Karna Ni Made Dwi Puspawati Nyoman Suryawati Nyoman Yoga Maya Pramita Nyoman Yoga Maya Pramita Prima Saraswati Sanjiwani Sudarsa Putu Ayu Saraswati Putu Dyah Sawitri Putu Gde Hari Wangsa Rania Ayu Permata Putri Kornia Ratih Purnamasari Nukana Ricky Fernando Maharis Rikcy Fernando Maharis Sadeli, Marrietta Sugiarti Santoso, Adeline Sawitri, Putu Dyah Sayu Widiawati, Sayu Stella, Aurelia Stephanie, Aurelia Vibriyanti Karna, NLP Ratih Winaya, Ketut Kwartantaya Wiraguna, A.A.G.P