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Hubungan Usia Dengan Estrogen Receptor Pada Penderita Kanker Payudara di RSUD Dr. Pirngadi Medan Tahun 2018
Jumikha Tamara Sahmaulyana Sidauruk
Nommensen Journal of Medicine Vol 6 No 1 (2020): Nommensen Journal of Medicine: Edisi Agustus
Publisher : Universitas HKBP Nommensen
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DOI: 10.36655/njm.v6i1.229
Background: Breast cancer is a malignancy in breast tissue that can be originated from ductal epithelium and lobules. It is the main cause of death from cancer suffered by women in the world. Age and hormonal are important risk factors for breast cancer where the longer a person is exposed to estrogen, the higher is the risk for breast cancer. The estrogen receptor is one of the main prognostic and predictive factors examined in breast cancer and can be determinant for hormonal therapy. Objectives: This study aimed to discover the relation between age and estrogen receptor in breast cancer patients of RSUD Dr.Pirngadi Medan in 2018. Methods: This research was an analytical study with a cross-sectional design. The research sample was 96 breast cancer patients by medical records of RSUD Dr.Pirngadi Medan in 2018 collected by a consecutive sampling method. Analysis of the data in this study was done by univariate to describe the characteristics of research subjects, while bivariate analysis used the chi-square test method to analyze the relationship between age and estrogen receptor. Results: The patients with breast cancer in RSUD Dr.Pirngadi Medan 2018 was mostly >40 years old (79.2%), with negative estrogen receptor hormonal status (53%), status was married (99%), and the highest level of education was high school (54.2%). The results of the study showed that there was a relationship between age and estrogen receptor in breast cancer patients with p-value =0.007 (p value<0,05). Conclusion: There was a significant relationship between age and estrogen receptors and estrogen receptors in breast cancer patients in RSUD Dr.Pirngadi Medan 2018.
Korelasi Antara Panjang Tulang Humerus Dengan Tinggi Badan Suku Batak di Universitas HKBP Nommensen Medan
Roy Abednego Purba;
Saharnauli Janna Verawaty Simorangkir;
Rebecca Rumesty Lamtiar
Nommensen Journal of Medicine Vol 6 No 1 (2020): Nommensen Journal of Medicine: Edisi Agustus
Publisher : Universitas HKBP Nommensen
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DOI: 10.36655/njm.v6i1.232
Background: Height is one of the data in the forensic identification process. The process of measuring height will be difficult if the bones or body parts found are not intact. Estimation of height can be facilitated by measuring the dimensions of long bones, one of which is the humerus. Analysis of the correlation of humerus bone length with height can support in determining the formula for estimating height based on humerus bone length. This study aims to determine the correlation between humerus bone length and Batak tribe height at HKBP Nommensen University, Medan. Method: This research was a descriptive analytic study with cross sectional design. The research sample was 72 students, lecturers, and employees consisting of 27 men and 45 Batak tribe women who met the inclusion and exclusion criteria at HKBP Nommensen University, Medan. Sampling is done by purposive sampling. Data analysis in this study was carried out by means of univariate and bivariate analysis using the Pearson and Spearman test methods to determine the correlation between humerus bone length variables and height variables. Result: The results obtained there is a strong correlation between humerus bone length and height in the Batak tribe with a correlation coefficient value r = 0.784 (p <0.05). Based on gender, men have weak and insignificant correlation strength with correlation coefficient r = 0.449 (p> 0.05) while women have strong and significant correlation r = 0.771 (p <0.05). Conclusion: There is a strong correlation between humerus bone length and Batak tribal height at HKBP Nommensen University, Medan.
Uji Aktivitas Antibakteri Dari Air Perasan Bawang Putih Terhadap Bakteri Salmonella Typhi
Olivia Yolanda Pasaribu;
Ade Pryta Simaremare;
Joseph Partogi Sibarani
Nommensen Journal of Medicine Vol 6 No 1 (2020): Nommensen Journal of Medicine: Edisi Agustus
Publisher : Universitas HKBP Nommensen
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DOI: 10.36655/njm.v6i1.233
Background : Garlic is a plant which is used to treat various types of diseases, especially the ones caused by bacterial infection. Allicin in garlic is one of the active compounds which has an antibacterial effect. Some studies found that garlic has an inhibitory effect on Salmonella typhi. Objective : This study aimed to determine the antibacterial effect of garlic juice against Salmonella typhi. Methods : This study was an experimental-laboratory research using disc diffusion method on MHA media. This study used five concentrations, namely 12.5%, 25%, 50%, 75%, and 100%. Amoxicillin and aquadest were used as positive and negative controls. The inhibition zone was determined by observing the clear zone around the disc then the results of the study were compared with positive control with CLSI 2017 guidance table where Salmonella typhi was susceptible when the amoxicillin inhibitory diameter zone was ≥ 17 mm, intermediate was 14-16 mm, and resistant was ≤ 13 mm. Results : The results showed that garlic juice has an antibacterial effect on various consentration. The minimum concentration of garlic juice to inhibit the growth of Salmonella typhi is on 50% with 19.25 mm diameters. Conclusion : There was an antibacterial effect of garlic juice on Salmonella typhi.
Korelasi Antara Panjang Tulang Radius Dengan Tinggi Badan Pada Suku Batak di Universitas HKBP Nommensen Medan
Genta Suci Anggitya Tobing;
Saharnauli Janna Verawaty Simorangkir;
Jenny Ria Sihombing
Nommensen Journal of Medicine Vol 6 No 2 (2021): Nommensen Journal of Medicine: Edisi Februari
Publisher : Universitas HKBP Nommensen
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DOI: 10.36655/njm.v6i2.234
Background: Dead victim and/ or found in unregocnized condition need to be identified. The identification of the unrecognized victim is carried out to prove that the skeleton is a human skeleton with ethnicity, race, sex, estimated age, height and special characteristics. Body height is a main characteristic which used as an identification process for various interests. Estimated body height can be measured based on long bones, which one of them is radius bone. Objective: This study aimed to determine the correlation between the length of the radius bone with body height of Bataknese student, lecturer, and staff at Universitas HKBP Nommensen Medan. Method: This research was an analytic study with cross-sectional design. The sample of this study was 72 students and employees of Universitas HKBP Nommensen Medan, consist of 27 Bataknese men and 45 Bataknese women who met the inclusion and exclusion criteria. Sampling technique was done by purposive sampling. Data analysis was done by univariate method to describe the characteristics of the subjects, normality test used the Kolmogorov-Smirnov test and bivariate analysis used the Pearson and Spearman tests to obtain the correlation between the radius bone length and body height. Results: The results of the study by sex, both men and women have a strong correlation value. Men have a correlation strength with r = 0.746 (p>0.05) and women have a correlation strength with r = 0.789 (p<0.05). Conclusion: There is a strong correlation between the length of the radius bone with body height of Bataknese students at Universitas HKBP Nommensen Medan.
Pengaruh Pemberian Alpukat terhadap Kadar Kolesterol LDL Darah pada Mahasiswa/i Obesitas di Fakultas Kedokteran Universitas HKBP Nommensen Medan
Komandaniel Simanullang;
Joseph Partogi Sibarani
Nommensen Journal of Medicine Vol 6 No 1 (2020): Nommensen Journal of Medicine: Edisi Agustus
Publisher : Universitas HKBP Nommensen
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DOI: 10.36655/njm.v6i1.237
Background: Low Density Lipoprotein (LDL) is a lipoprotein that contains more cholesterol. High levels of blood LDL cholesterol are associated with obesity and increased of risk factor of cardiovascular disease. Avocado (Persea americana) is a well known and popular fruit in society. The active ingredient (omega 9-oleic acid) of avocados can be use to decrease LDL cholesterol levels and increase HDL (High Density Lipoprotein) cholesterol levels in blood in order to reduce the risk factor of cardiovascular disease. Objective: This study aims to determine the effect of avocado consumption on blood LDL cholesterol levels in obese students in Medical Faculty of Universitas HKBP Nommensen. Method: This study used a pre-experimental design one group pretest and posttest study. Subjects were 20 obese students of Medical Faculty of Universitas HKBP Nommensen and selected by simple random sampling technique. For the first 14 days, samples are given dietary intervention and the next 14 days given dietary intervention and avocado juice. Measurement of LDL cholesterol levels was done before and after 14 days given avocado juice. Data analysis used paired T test to analyze differences in blood LDL cholesterol levels before and after being given avocado juice. Results: The results are average value of blood LDL cholesterol levels on pretest was 137.1 mg / dL and posttest was 128.25 mg / dL with mean reduction was 8.85 mg / dL. Paired T test analysis shows that the avocados effect to blood LDL cholesterol is significantly influenced with value of p = 0.036 (p <0.05). Conclusion: There is an effect of avocado consumption on blood LDL cholesterol levels.
Pengaruh Pemberian Alpukat Terhadap Kadar Kolesterol Total Darah Pada Mahasiswa/i Obesitas Di Fakultas Kedokteran Universitas HKBP Nommensen Medan Tahun 2019
Syupiarni Putri Waruwu;
Joseph Partogi Sibarani;
Saharnauli Janna Verawaty Simorangkir
Nommensen Journal of Medicine Vol 6 No 2 (2021): Nommensen Journal of Medicine: Edisi Februari
Publisher : Universitas HKBP Nommensen
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DOI: 10.36655/njm.v6i2.240
Background: Cholesterol is a fat that does not dissolve easily in the blood. Most of the cholesterol in the blood is attached to specific protein carriers in the plasma in the form of lipoprotein complexes, which are soluble in water. Lipoprotein which carries cholesterol throughout the body. namely LDL (Low Density Lipoprotein) and HDL (High Density Lipoprotein). An increase in LDL in the body tends to form atherosclerosis. In contrast HDL cholesterol inhibits LDL oxidation so that atherosclerotic plaque formation does not occur. Obesity is one of the risk factors for atherosclerosis with manifestations of coronary heart disease. Handling of obesity has been done by many researchers and implemented. One ingredient from nature that serves as an alternative ingredient to lower blood cholesterol levels is avocado. Objective: To determine the effect of avocado administration on total blood cholesterol levels in the obese college students at the Medical Faculty of Nommensen HKBP University in 2019. Methods :This research is a pre-experimental study with a pre-post test design in one group. The sample was selected by purposive sampling method and obtained 20 obese students. Subjects consumed avocado juice every day for 14 days. Total cholesterol levels were measured before (day 0) and after (day 14) treatment. Results: The mean total cholesterol level of the subject's blood on the pretest examination was 188.10 mg / dL and the posttest examination was 180.05 mg / dL. There was a decrease in the average total blood cholesterol level of 8.05 mg / dl. Paired T-test showed that there was a non-significant decrease in mean total blood cholesterol level with a value of p = 0.068 (p <0.05). Conclusion: In this study there was no effect of avocado administration on total blood cholesterol levels in obese students.
Hubungan Mekanisme Koping Dengan Kualitas Hidup Pasien Gagal Ginjal Kronik yang Menjalani Hemodialisis di Rumah Sakit Santa Elisabeth Medan
Meiling Siahaan;
Rosminta Girsang;
Ade Pryta Simaremare
Nommensen Journal of Medicine Vol 6 No 1 (2020): Nommensen Journal of Medicine: Edisi Agustus
Publisher : Universitas HKBP Nommensen
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DOI: 10.36655/njm.v6i1.241
Background: Chronic kidney failure is a state of progressive, irreversible destruction of kidney structure that requires permanent kidney replacement therapy. Global prevalence is 11.7% -15.1%. Chronic disease conditions and prolonged treatment can affect the patient's mental health and quality of life. The process by which a person attains physical and mental readiness in dealing with stressful situations is called coping. Quality of life is an individual's perception of their position in life. The aim of this study was to determine the relationship between coping mechanisms and quality of life in patients with chronic renal failure undergoing hemodialysis. Method: This research was analytical correlative with cross sectional research design. Sampling with consecutive sampling technique and obtained as many as 35 respondents. The criteria for patients in this study were patients diagnosed with chronic renal failure and undergoing hemodialysis with an age limit of 18 - 65 years, compos mentis awareness status and willingness to become respondents. The study was conducted in November 2019- January 2020. Patient data were obtained through medical records and questionnaires kidney disease quality of life short form (KDQOL-SF) and a brief cope scale. Results: The results of statistical tests obtained p value = 0.007 and r = 0.413 (p <0.05; r> 0.05). These results indicate that there is a relationship between coping mechanisms and quality of life in patients with chronic renal failure undergoing hemodialysis. More male respondents than women with 56-65 years age group, the highest education status is college; working as a civil servant, long undergoing HD 1-12 months. Based on statistical analysis it is known that the coping mechanism of poor respondents (57.1%), poor quality of life (54.3%). Conclusion: There was significant relationship between coping mechanisms with the quality of life of patients with chronic renal failure undergoing hemodialysis with moderate correlation strength and positive direction.
Manifestasi Penyakit Kulit pada Pasien Diabetes Melitus Tipe 2 di Rumah Sakit Dr. Pirngadi Medan
Dione Larissa Simanjuntak;
Kristo Nababan;
Joseph Sibarani
Nommensen Journal of Medicine Vol 6 No 2 (2021): Nommensen Journal of Medicine: Edisi Februari
Publisher : Universitas HKBP Nommensen
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DOI: 10.36655/njm.v6i2.242
Background: Diabetes mellitus (DM) is a metabolic group with characteristic hyperglycemia that occurs due toabnormal insulin secretion, insulin action, or both. DM is often called the silent killer because the patients knowthey has DM only after the patient experiencing complications and manifestations. It is estimated that 30-70% of DM patients experience skin manifestations during the disease process. The relationship between the appearance of skin manifestations with diabetes mellitus is not yet known, but it is suspected due to chronic hyperglycemia and abnormalities of the immune system.Objective: To determine skin diseases in patients with type 2 diabetes at General Hospital Dr. Pirngadi Medan.Methods: This research was a descriptive study with a cross-sectional study design conducted at Dr. GeneralHospital Pirngadi Medan. Data collection was carried out through 29 medical records of patients with diabetesmellitus from January 2018 to December 2018. Samples were selected by total sampling.Results: From 29 samples studied, there were six types of skin manifestations. The most common skinmanifestations are Diabetic Ulcer (62.07%), followed by Steven Johnson Syndrome and diabetic gangrene, which both are equally 13.80%. The other skin manifestations are herpes zoster, gluteal abscess, and bullous pemphigoid (3.44%).Conclusion: The most common manifestation of the skin in patients with type 2 DM is Diabetic Ulcer.
Gambaran Profil Hematologi Dalam 24 Jam Pertama Pada Pasien Sepsis Di Unit Neonatus RSUD Dr. Pirngadi Medan Tahun 2017-2018
Alpa Exaudi Siahaan;
Johan Christian Silaen;
Leo Simanjuntak
Nommensen Journal of Medicine Vol 6 No 2 (2021): Nommensen Journal of Medicine: Edisi Februari
Publisher : Universitas HKBP Nommensen
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DOI: 10.36655/njm.v6i2.243
Background: Neonatal sepsis is a clinical syndrome on infants aged 28 days or more. According to WHO data on 19th April 2018, estimated 3 million newborns and 1.2 million children suffer from sepsis globally every year. Hematological profile assessment can be used as a clinical guide to diagnose sepsis and early management of patients with early onset, especially in hospitals with limited facilities and the examination data can be obtained faster. Objective: This study was aimed to determine the hematological profile in sepsis patients in neonatal unit at RSUD Dr. Pirngadi Medan. Method: This research was a descriptive cross-sectional design. The research sample was selected by total sampling. Results: The results of the study were found from 74 neonates, 44 (59.5%) were male. Neonates with normal labor were 57 (78.1%) and survived 45 (60.8%). It was found that leukocytes (76.4%), neutrophils (60%), monocytes (87.9%), and hemoglobin (40.3%) were increased. Conclusion: The hematological profile can be used as a clinical assessment of sepsis at the first 24 hours on neonates. Hematological examination found an increased leukocytes, neutrophils, monocytes, and hemoglobin in neonatal sepsis patients at the first 24 hours.
Hubungan Antara Motivasi Belajar Dengan Prestasi Belajar Mahasiswa/i Fakultas Kedokteran Universitas HKBP Nommensen
Henny Erina Saurmauli Ompusunggu
Nommensen Journal of Medicine Vol 6 No 1 (2020): Nommensen Journal of Medicine: Edisi Agustus
Publisher : Universitas HKBP Nommensen
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DOI: 10.36655/njm.v6i1.247
Background : Quality human resource are needed by our country in order to compete with other countries. Indicator of quality human resources graduated from university are good academic achievements. Academic achievement is affected by several factors, such as learning motivation. The aim of this study is to determine the correlation between learning motivation and academic achievements in Medical Faculty of Universitas HKBP Nommensen students. Methods: This research was an analytic study. Respondents of this study were 148 active students of Universitas HKBP Nommensen. Learning motivation skor were obtained using an intrinsic motivation questionnaire and academic achievements were obtained from cumulative achievement index. Pearson test was used to analyzed the correlation between learning motivation and academic achievements of respondents. Results: Medical Faculty of Universitas HKBP Nommensen students majority had high learning motivation with academic achievments 3,19 ± 0,28. There was no correlation between learning motivation and academic achievements in Medical Faculty of Universitas HKBP Nommensen students (p = 0,227). Conclusion: There is no correlation between learning motivation and academic achievements in Medical Faculty of Universitas HKBP Nommensen students.