Claim Missing Document
Check
Articles

Found 12 Documents
Search

Seorang Pria 21 Tahun dengan Urin Berwarna Gelap Joseph Partogi Sibarani
Nommensen Journal of Medicine Vol 5 No 1 (2019): Nommensen Journal of Medicine
Publisher : Universitas HKBP Nommensen

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (191.955 KB) | DOI: 10.36655/njm.v5i1.82

Abstract

First published by Strubing in 1882, Paroxysmal Nocturnal Hemoglobinuria (PNH) is a chronic acquired disorder characterized by the occurrence of intravascular hemolysis and hemoglobinuria which commonly occurs when patients sleep at night, caused by cellular abnormalities due to somatic mutations that cause intrinsic damage on the red blood cell membrane, making it more susceptible to complement lysis. The incidence of PNH varies greatly in various populations and is more common in Southeast Asia. In general, the incidence is estimated to be 1 -1.5 cases / million population. This case is more common in young adults, but can also be found in children and parents. In general the clinical picture of PNH includes symptoms of anemia, hemoglobinia, signs of bleeding, and gastrointestinal complaints. Diagnosis can be determined through blood, urine, bone marrow and cytogenetic examination. We reported the case of a 21-year-old man with complaints of pale face, easy fatigue and tea colored urine in the morning. After several laboratory tests and aspiration of the bone marrow, PNH diagnosis is made. Glucocorticoids used as therapy, and patients are discharged with clinical improvement.
Uji Aktivitas Antibakteri Dari Air Perasan Bawang Putih Terhadap Bakteri Salmonella Typhi Olivia Yolanda Pasaribu; Ade Pryta Simaremare; Joseph Partogi Sibarani
Nommensen Journal of Medicine Vol 6 No 1 (2020): Nommensen Journal of Medicine: Edisi Agustus
Publisher : Universitas HKBP Nommensen

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (242.231 KB) | DOI: 10.36655/njm.v6i1.233

Abstract

Background : Garlic is a plant which is used to treat various types of diseases, especially the ones caused by bacterial infection. Allicin in garlic is one of the active compounds which has an antibacterial effect. Some studies found that garlic has an inhibitory effect on Salmonella typhi. Objective : This study aimed to determine the antibacterial effect of garlic juice against Salmonella typhi. Methods : This study was an experimental-laboratory research using disc diffusion method on MHA media. This study used five concentrations, namely 12.5%, 25%, 50%, 75%, and 100%. Amoxicillin and aquadest were used as positive and negative controls. The inhibition zone was determined by observing the clear zone around the disc then the results of the study were compared with positive control with CLSI 2017 guidance table where Salmonella typhi was susceptible when the amoxicillin inhibitory diameter zone was ≥ 17 mm, intermediate was 14-16 mm, and resistant was ≤ 13 mm. Results : The results showed that garlic juice has an antibacterial effect on various consentration. The minimum concentration of garlic juice to inhibit the growth of Salmonella typhi is on 50% with 19.25 mm diameters. Conclusion : There was an antibacterial effect of garlic juice on Salmonella typhi.
Pengaruh Pemberian Alpukat terhadap Kadar Kolesterol LDL Darah pada Mahasiswa/i Obesitas di Fakultas Kedokteran Universitas HKBP Nommensen Medan Komandaniel Simanullang; Joseph Partogi Sibarani
Nommensen Journal of Medicine Vol 6 No 1 (2020): Nommensen Journal of Medicine: Edisi Agustus
Publisher : Universitas HKBP Nommensen

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (287.11 KB) | DOI: 10.36655/njm.v6i1.237

Abstract

Background: Low Density Lipoprotein (LDL) is a lipoprotein that contains more cholesterol. High levels of blood LDL cholesterol are associated with obesity and increased of risk factor of cardiovascular disease. Avocado (Persea americana) is a well known and popular fruit in society. The active ingredient (omega 9-oleic acid) of avocados can be use to decrease LDL cholesterol levels and increase HDL (High Density Lipoprotein) cholesterol levels in blood in order to reduce the risk factor of cardiovascular disease. Objective: This study aims to determine the effect of avocado consumption on blood LDL cholesterol levels in obese students in Medical Faculty of Universitas HKBP Nommensen. Method: This study used a pre-experimental design one group pretest and posttest study. Subjects were 20 obese students of Medical Faculty of Universitas HKBP Nommensen and selected by simple random sampling technique. For the first 14 days, samples are given dietary intervention and the next 14 days given dietary intervention and avocado juice. Measurement of LDL cholesterol levels was done before and after 14 days given avocado juice. Data analysis used paired T test to analyze differences in blood LDL cholesterol levels before and after being given avocado juice. Results: The results are average value of blood LDL cholesterol levels on pretest was 137.1 mg / dL and posttest was 128.25 mg / dL with mean reduction was 8.85 mg / dL. Paired T test analysis shows that the avocados effect to blood LDL cholesterol is significantly influenced with value of p = 0.036 (p <0.05). Conclusion: There is an effect of avocado consumption on blood LDL cholesterol levels.
Pengaruh Pemberian Alpukat Terhadap Kadar Kolesterol Total Darah Pada Mahasiswa/i Obesitas Di Fakultas Kedokteran Universitas HKBP Nommensen Medan Tahun 2019 Syupiarni Putri Waruwu; Joseph Partogi Sibarani; Saharnauli Janna Verawaty Simorangkir
Nommensen Journal of Medicine Vol 6 No 2 (2021): Nommensen Journal of Medicine: Edisi Februari
Publisher : Universitas HKBP Nommensen

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (220.113 KB) | DOI: 10.36655/njm.v6i2.240

Abstract

Background: Cholesterol is a fat that does not dissolve easily in the blood. Most of the cholesterol in the blood is attached to specific protein carriers in the plasma in the form of lipoprotein complexes, which are soluble in water. Lipoprotein which carries cholesterol throughout the body. namely LDL (Low Density Lipoprotein) and HDL (High Density Lipoprotein). An increase in LDL in the body tends to form atherosclerosis. In contrast HDL cholesterol inhibits LDL oxidation so that atherosclerotic plaque formation does not occur. Obesity is one of the risk factors for atherosclerosis with manifestations of coronary heart disease. Handling of obesity has been done by many researchers and implemented. One ingredient from nature that serves as an alternative ingredient to lower blood cholesterol levels is avocado. Objective: To determine the effect of avocado administration on total blood cholesterol levels in the obese college students at the Medical Faculty of Nommensen HKBP University in 2019. Methods :This research is a pre-experimental study with a pre-post test design in one group. The sample was selected by purposive sampling method and obtained 20 obese students. Subjects consumed avocado juice every day for 14 days. Total cholesterol levels were measured before (day 0) and after (day 14) treatment. Results: The mean total cholesterol level of the subject's blood on the pretest examination was 188.10 mg / dL and the posttest examination was 180.05 mg / dL. There was a decrease in the average total blood cholesterol level of 8.05 mg / dl. Paired T-test showed that there was a non-significant decrease in mean total blood cholesterol level with a value of p = 0.068 (p <0.05). Conclusion: In this study there was no effect of avocado administration on total blood cholesterol levels in obese students.
Manifestasi Penyakit Kulit pada Pasien Diabetes Melitus Tipe 2 di Rumah Sakit Dr. Pirngadi Medan Dione Larissa Simanjuntak; Kristo Nababan; Joseph Sibarani
Nommensen Journal of Medicine Vol 6 No 2 (2021): Nommensen Journal of Medicine: Edisi Februari
Publisher : Universitas HKBP Nommensen

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (185.571 KB) | DOI: 10.36655/njm.v6i2.242

Abstract

Background: Diabetes mellitus (DM) is a metabolic group with characteristic hyperglycemia that occurs due toabnormal insulin secretion, insulin action, or both. DM is often called the silent killer because the patients knowthey has DM only after the patient experiencing complications and manifestations. It is estimated that 30-70% of DM patients experience skin manifestations during the disease process. The relationship between the appearance of skin manifestations with diabetes mellitus is not yet known, but it is suspected due to chronic hyperglycemia and abnormalities of the immune system.Objective: To determine skin diseases in patients with type 2 diabetes at General Hospital Dr. Pirngadi Medan.Methods: This research was a descriptive study with a cross-sectional study design conducted at Dr. GeneralHospital Pirngadi Medan. Data collection was carried out through 29 medical records of patients with diabetesmellitus from January 2018 to December 2018. Samples were selected by total sampling.Results: From 29 samples studied, there were six types of skin manifestations. The most common skinmanifestations are Diabetic Ulcer (62.07%), followed by Steven Johnson Syndrome and diabetic gangrene, which both are equally 13.80%. The other skin manifestations are herpes zoster, gluteal abscess, and bullous pemphigoid (3.44%).Conclusion: The most common manifestation of the skin in patients with type 2 DM is Diabetic Ulcer.
MENINGKATKAN KEMAMPUAN KETRAMPILAN BERNYANYI GENERASI MUDA DI GEREJA HKBP BERASTAGI KABUPATEN KARO Junita Batubara; Jubilezer Sihite; Ken Steven; Ronald Heriko Saragih; Kamaluddin Galingging; Emmi Simangunsong; Ance J. Panggabean; Joseph Sibarani
Community Development Journal : Jurnal Pengabdian Masyarakat Vol. 4 No. 1 (2023): Volume 4 Nomor 1 Tahun 2023
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/cdj.v4i2.12034

Abstract

Huria Kristen Batak Protestan atau yang biasa disebut dengan HKBP, sebagian besar jemaatnya adalah orang Nasrani yang bersuku Batak. Sampai Sekarang gereja HKBP sudah menyebar luas hingga ke luar negeri. Pada Kesempatan ini, Pengabdian Masyarakat dilaksanakan di Gereja HKBP Berastagi, dimana gereja ini berdiri pada tahun 1940, dengan jumlah anggota jemaatnya sekitar 1424 orang (156 KK). Gereja ini melakukan kebaktian ibadah setiap Minggunya sebanyak dua kali yaitu pada pukul 08.00wib dan pukul 10.00wib. Dilihat dari jumlah jemaatnya, lebih banyak orangtua (lansia) sebagai anggota gereja daripada naposobulung atau disebut muda-mudi gereja. Kemampuan bernyanyi muda-mudinya, bisa dikatakan kurang mampu dikarenakan kurangnya pelatihan bernyanyi khususnya nyanyian dari Buku Ende. Dengan adanya fakta tersebut maka dilakukanlah pelatihan bernyanyi untuk menambah ketrampilan muda-mudi gereja sebagao songlieder. Adapun metode yang digunakan adalah dengan melakukan ceramah dan pelatihan langsung terhadap mereka dengan cara pengenalan frasering, artikulasi, vibrasi, dan intonasi. Berdasarkan uraian latar belakang di atas maka pelatih menerapkan bagaimana teknik vokal yang benar dari lagu Buku Ende Nomor 716 “Di Na Mamolus Sandok Ngoluon”di gereja HKBP Berastagi khususnya sebagai seorang song lieder, sehingga mereka mampu menyanyikan lagu tersebut ketika saat ibadah di gereja HKBP Berastagi.
Hubungan Merokok Dengan Terbentuknya Lesi Kavitas Paru Pada Pasien Tuberkulosis RSUP H Adam Malik Elisa Rinaldo Perdamenta; Henny Erina Saurmauli Ompusunggu; Joseph Partogi Sibarani
Jurnal Ilmu Kedokteran Vol 17, No 2 (2023): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26891/JIK.v17i2.2023.111-116

Abstract

In 2022, 10,6 million people in the world were infected with tuberculosis and Indonesia ranks second. As many as 8 million of the world’s population died from tobacco smoking in 2021. Cavitary lung lesions are cavities filled with air in the lungs and smoking can directly damage lung parenchyma due its contents so tuberculosis patients who smoke are more risk of developing lung cavities. This study aims to determine association between smoking and formation of lung cavity. This study was an observational analytic study with case-control design using 80 samples consisting of 40 smoking and 40 non-smoker patients. Sample selection used purposive sampling technique and samples were collected from medical records in 2021. Data analysis used chi-square test. It was found that patients with lung cavity were 46,3% and patients who smoked and had lung cavity were 30%. Based on the result of data analysis, it can be concluded that there is a significant relationship between smoking and the formation of lung cavity lesions in tuberculosis patients at RSUP H Adam Malik with p = 0,014 (p < 0,05) and tuberculosis patients who smoke have a risk of 3,115 times to have lung cavity lesions (OR = 3,115).
DOES THE NIAS TRIBE'S HEAD CIRCUMFERENCE CORRELATE WITH BODY HEIGHT? Windy Juwita Lumbanraja; Saharnauli Janna Verawaty Simorangkir; Joseph Partogi Sibarani
Majalah Biomorfologi Vol. 34 No. 2 (2024): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v34i2.2024.93-101

Abstract

Highlights A significant correlation was found between head circumference and height among Nias tribe students. This study was conducted to obtain formulations on weight determination based on headbands in the Nias tribe.   Abstract Background:  Anthropometric measures are one of the protocols frequently employed to identify deceased bodies. Height, age, and gender are a few anthropometric traits that might be utilized to identify the victim from the corpse. If body components are absent, head circumference can be used to determine body height. Objective: The goal of the study was to ascertain whether there is a correlation between head circumference and body height by gender and to create formulas for estimating weight based on head circumference in the Nias tribe at the University of HKBP Nommensen Medan, Indonesia. Material and Method: The study was conducted from September to October 2023 at the University of HKBP Nommensen using an observational cross-sectional design. Of the 100 students who met the inclusion criteria, 50 were men, and the remaining 50 were women. The study's dependent variable was micro-toise-measured height. The head circumference, expressed in meters of tape, served as the study variable. Result: Statistical analysis of the study results from a significant correlation between the head circumference and the height (r = 0.655, p<0.01). The linear regression equation obtained was y = 3200 x - 2.672 in men and y = 10970 + 2.728 times in women, where y was height and x was head circumference. Conclusion: A substantial height-head circumference association was found among the Nias tribe at the University of HKBP Nommensen Medan, Indonesia. The identification method of the forensic field may benefit from this research. 
Hubungan Rasio Neutrofil-Limfosit (RNL) dengan Derajat Keparahan Pasien COVID-19 di Rumah Sakit Martha Friska Medan Tahun 2021 Sipahutar, Nathalia Elizabeth Rouli; Dairi, Leonardo Basa; Sibarani, Joseph Partogi; Sihombing, Jenny Ria
Nommensen Journal of Medicine Vol 9 No 1 (2023): Nommensen Journal of Medicine: Edisi Agustus
Publisher : Universitas HKBP Nommensen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36655/njm.v9i1.688

Abstract

ABSTRACT Background: COVID-19 is a disease caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) which is rapidly transmitted in humans. Systemic inflammation will cause changes in leukocytes in the circulation which can lead to neutrophilia and lymphocytopenia. In COVID-19, the neutrophil-lymphocyte ratio (NLR) can be used as a predictor of disease severity in the early stages. An increase in NLR can reflect an increased inflammatory process and can predict severity. This study aims to determine relationship between NLR and the severity of COVID-19 patients at Martha Friska Hospital Medan in 2021. Methods: The design of this research is observational analytic with cross sectional method. Samples was taken from medical records of COVID-19 patients at Martha Friska Hospital Medan from January-March 2021 with consecutive sampling method and obtained 74 samples. This research was done in November 2021. The analysis of the data processed by the univariate frequency distribution table and the SPSS version 25 program was carried out bivariately using the Chi Square test. Results: From 74 COVID-19 patients, RNL <3.13 obtained 29 people (93%) with mild severity, 2 people (7%) moderate severity and no patients with severe-critical severity. COVID-19 patients with RNL 3.13 is 6 people (14%) with mild severity, 20 people (46%) with moderate severity, 17 people (40%) with severe-critical severity. This study showed there was a relationship between NLR and the severity of COVID-19 patients (p=0.000). Conclusion: There is a relationship between NLR and the severity of COVID-19 patients. Keywords : COVID-19 severity, neutrophil-lymphocyte ratio ABSTRAK Latar Belakang : COVID-19 adalah suatu penyakit yang disebabkan oleh Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) yang bersifat cepat menular sesama manusia. Peradangan yang terjadi secara sistemik dapat menyebabkan perubahan leukosit dalam sirkulasi yang dapat membuat perubahan pada neutrofilia dan limfositopenia. Rasio neutrofil-limfosit (RNL) pada pasien COVID-19 dapat digunakan sebagai prediktor keparahan penyakit pada fase awal infeksi penyakit. RNL yang meningkat dapat diartikan sebagai proses peningkatan inflamasi. Penelitian ini bertujuan untuk mengetahui hubungan antara RNL dengan derajat keparahan pasien COVID-19 di Rumah Sakit Martha Friska Medan tahun 2021. Metode : Penelitian ini memiliki desain analitik observasional dengan metode cross sectional. Sampel penelitian diambil dari data rekam medik pasien COVID-19 di Rumah Sakit Martha Friska Medan dari Januari-Maret 2021 dengan metode consecutive sampling dan didapatkan 74 sampel. Penelitian dilakukan pada bulan November 2021. Analisis data yang diolah dengan tabel distribusi frekuensi secara univariat dan dengan program SPSS versi 25 dilakukan secara bivariat menggunakan uji Chi Square. Hasil : Dari 74 pasien COVID-19, nilai RNL 3,13 didapatkan 29 orang (93%) dengan derajat keparahan ringan, 2 orang (7%) derajat keparahan sedang dan tidak didapatkan pasien dengan derajat keparahan berat-kritis. Pasien COVID-19 dengan RNL 3,13, sebanyak 6 orang (14%) derajat keparahan ringan, 20 orang (46%) dengan derajat keparahan sedang, 17 orang (40%) derajat keparahan berat-kritis. Penelitian ini menunjukkan terdapat hubungan antara RNL dengan derajat keparahan pasien COVID-19 (p=0,000). Kesimpulan : Terdapat hubungan antara RNL dengan derajat keparahan pasien COVID-19. Katakunci : Derajat keparahan COVID-19, rasio neutrofil-limfosit
Hubungan Kadar Hemoglobin Glikosilat (HbA1c) dengan Kandidiasis Kutis pada Pasien Diabetes Melitus Tipe 2 di Rumah Sakit Umum Daerah Dr. Pirngadi Medan Pada tahun 2019 Agatha, Theresia Christin; Marpaung, Okto; Sibarani, Joseph
Nommensen Journal of Medicine Vol 9 No 1 (2023): Nommensen Journal of Medicine: Edisi Agustus
Publisher : Universitas HKBP Nommensen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36655/njm.v9i1.1054

Abstract

Background: Cutaneous candidiasis is a fungal infection of the skin caused by yeast or microorganisms belonging to the genus Candida. It is known that diabetes mellitus is one of the predisposing factors for candidiasis cutis caused by changes in the body's defense system. Diabetes mellitus is a metabolic disease characterized by hyperglycemia resulting from defects in insulin secretion or insulin action. Starting from the autoimmune destruction of pancreatic cells resulting in insulin deficiency to abnormalities resulting in resistance to insulin action. To determine a person's level of glucose control, an HbA1c examination is needed. This test will show the average blood sugar level over the last 90 days and represent a percentage. This test can also be used to diagnose diabetes. Objective: To analyze the relationship between HbA1c levels and cutaneous candidiasis in type 2 diabetes mellitus patients. Methods: This study is an observational analytic study with a retrospective design. To determine the relationship between glycosylated hemoglobin (HbA1c) levels and cutaneous candidiasis in type 2 diabetes mellitus patients. On examination of HbA1c levels it can be said to be controlled < 6.5% and not controlled > 6.5%. Results: The results of this study were taken from 62 patient medical record data according to the inclusion and exclusion criteria, it was found that the majority of patients with type 2 diabetes mellitus were women aged ≥55 years. Based on HbA1c levels, the patients in this study were more dominantly uncontrolled with negative cutaneous candidiasis, 56 (90.3%). The results of Fisher's exact analysis showed p-value = 1.000 (p > 0.05) meaning that there was no significant relationship between HbA1c levels and cutaneous candidiasis. Conclusion: There is no significant relationship between HbA1c levels and the incidence of cutaneous candidiasis.