cover
Contact Name
Dr. Nuri Nurlaila Setiawan
Contact Email
editor3bio@sith.itb.ac.id
Phone
+62222511575
Journal Mail Official
support3bio@sith.itb.ac.id
Editorial Address
Sekolah Ilmu dan Teknologi Hayati, Institut Teknologi Bandung Labtek XI, Jl. Ganesha 10 Bandung 40132 West Java - Indonesia
Location
Kota bandung,
Jawa barat
INDONESIA
3BIO: Journal of Biological Science, Technology and Management
ISSN : -     EISSN : 26558777     DOI : http://dx.doi.org/10.5614%2F3bio.2020.2.1
3Bio: Journal of Biological Science, Technology and Management is an interdisciplinary peer-reviewed journal in a wide aspect related to the field of life sciences and other related fields of study. The journal aims to promote scientific discourse and disseminate research on various branches and applications of bio-science, biotechnology and bio-based management. This journal invites original empirical research, literature reviews, theoretical or methodological contributions, or short communications on, but not limited to, the following topics: - Ecology and Biosystematics - Microbiology - Genetics and Molecular Biology - Animal Development and Physiology - Plant Development and Physiology - Entomology - Biomedical science - Biochemistry - Agronomy - Forestry - Bioengineering - Bioethics - Management of Biological Resources The journal also invites contributions from other associated disciplines. This journal is an open-access journal. Readers may read, download, copy, distribute, print, search, or link to the full texts of these articles without any charge, provided that readers acknowledge the Creative Commons attached to the articles. All submitted papers are reviewed by at least two referees before being accepted for publication, following a double-blind review process. This journal is delivered in an academic English and rigorously edited to provide a quality standard of a scientific journal. This journal is managed by the School of Life Sciences and Technology, Institut Teknologi Bandung, Indonesia.
Articles 74 Documents
In Vitro Bacterial Activity of Seaweed (Kappaphycus alvarezii) Against Vibrio harveyi Rukisah, Rukisah; Rahmawati, Rahmawati; Simanjuntak, Ricky Febrinaldy
3BIO: Journal of Biological Science, Technology and Management Vol. 8 No. 1 (2026): Vol 8 No 1 (2026)
Publisher : School of Life Sciences and Technology, Institut Teknologi Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/3bio.2026.8.1.5

Abstract

Tiger shrimp (Penaeus monodon) is one of the featured products in Kalimantan Utara that still apply organic or traditional pond methods. Currently, production tiger shrimp has decreased due to a disease caused by Vibrio harveyi bacteria, which causes luminescent Vibrio disease or Vibriosis. Antibiotics are commonly used to treat this disease, but prolonged administration can lead to bacterial resistance The use of natural ingredients is an alternative solution to replace antibiotics, one of which is seaweed (Kappaphycus alvarezii). This study aims to determine the in-vitro inhibitory effect of seaweed extract against the growth of V. harveyi. This study using quantitative descriptive wih Kappaphycus alvarezii seeds from traditional farmers in Tarakan, Indonesia. Methods that were used in this research consisted of K. alvarezii extract preparation, bacteria preparation, phytochemical assay, and antibacterial assay of the extract followed by data analysis. The phytochemical assay consisted of alkaloid, phenol, flavonoid, saponin, and steroid assay. The antibacterial activity was evaluated using the paper disc diffusion method with seaweed extract concentrations of 5%, 10%, 15%, and 20%, while tetracycline served as the positive control and a solvent-only disc as the negative control. The results of phytochemical assay showed that the K. alvarezii extract contained alkaloid, phenol, flavonoid, saponin, and steroid. The antibacterial test showed that the seaweed extract with a concentration of 5% had an inhibition zone of 7 mm, 10% of 7.1 mm, 15% of 7.3 mm and at a concentration of 20% had the largest zone of inhibition with an inhibiton diameter of 13.3 mm. Based on these results, it can be concluded that the provision of Kappaphycus alvarezii is potentially inhibit the growth of V. harveyi in vitro but not significantly different when compared to the positive control. This activity is likely attributed to the natural compounds present in K. alvarezii, such as alkaloids, phenols, flavonoid, saponin, and steroids, which are known to possess antibacterial properties.
Strategic Alliances in the Biotechnology Industry: A Systematic Literature Review of Drivers, Outcomes, and Future Research Directions Cikal Rambasae N; Ariska, Wiwik
3BIO: Journal of Biological Science, Technology and Management Vol. 8 No. 1 (2026): Vol 8 No 1 (2026)
Publisher : School of Life Sciences and Technology, Institut Teknologi Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/3bio.2026.8.1.6

Abstract

Strategic alliances play a pivotal role in the innovation-driven and uncertain landscape of the biotechnology industry. This study consolidates fragmented insights through a systematic literature review (SLR) of 161 peer-reviewed articles (1985–2025), following the PRISMA framework and combining bibliometric and thematic analyses. The review maps intellectual structures, thematic clusters, and geographical trends. Findings show that the field is anchored in innovation, biotechnology, and strategic planning, with strong contributions from the United States, while areas such as agricultural biotechnology, sustainability, and human capital remain underexplored. Thematic mapping indicates mature versus emerging themes, highlighting the rising importance of digitalization, inclusive innovation, and dynamic capabilities. Beyond mapping intellectual evolution, this review contributes theoretically by clarifying the role of alliances as vehicles for capability building, risk sharing, and knowledge flows. Methodologically, it demonstrates the value of integrating bibliometric and thematic approaches in systematic reviews. Practically, it offers guidance for managers and policymakers seeking collaborative solutions to address global health, environmental, and technological challenges.
Diversity and Community Structure of Fish in Saguling Hydroelectric Power Plant (PLTA) Area, Bandung Barat Regency Hasbiyan Rosyadi; Muhammad Rahardian Adila Haqqi; Avandi Latrianto; Muhammad Ainur Rafiq; Ulinuha Dzulfi Nuryanda
3BIO: Journal of Biological Science, Technology and Management Vol. 8 No. 1 (2026): Vol 8 No 1 (2026)
Publisher : School of Life Sciences and Technology, Institut Teknologi Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/3bio.2026.8.1.1

Abstract

Aligning the sustainability effort of the Saguling Hydroelectric Power Plant (PLTA), Bandung Barat Regency, this study was conducted to understand the aquatic ecosystem balance through the diversity and community structure of the fish on those area. Data collection was conducted in July-September 2024 on 6 stations, which includes the environmental and fish diversity data through active method by direct capture and VES (Visual Encounter Survey), and also passive method through trapping and observation to the fish caught by fishermen or local residents. Data analysis was carried out through diversity, evenness, and species richness. Based on data collected, 570 fish from 22 species and 15 different families were found. The mostly found species were guppy (P. reticulata), pepetek (L. equulus), and red devil fish (a. labiatus). The environment of study area location in general has good circumstances of water quality to support fish lives and other fisheries activity (class 2 to 3) regarding to water quality standard. Based on ecological index calculation results, study area location has a medium diversity with a score of 2.548, high evenness with a score of 0.813, and medium species richness with a score od 3.464. While station 6 (Cicangkang Hilir) has the overall highest index compared to other stations.
The Effect of Acidity on the Growth and Chlorophyll a Content of Latoh (Caulerpa racemosa) Vidyaningrum, Caretta Trisari; Harwanto, Dicky; Windarto, Seto
3BIO: Journal of Biological Science, Technology and Management Vol. 8 No. 1 (2026): Vol 8 No 1 (2026)
Publisher : School of Life Sciences and Technology, Institut Teknologi Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/3bio.2026.8.1.3

Abstract

Caulerpa racemosa is an edible green macroalga rich in chlorophyll. pH is a key environmental factor influencing seaweed performance, including growth and chlorophyll content. This study tested how pH affects growth and chlorophyll a in C. racemosa and identified the optimal pH. Experiments were conducted from November 2024 to January 2025 at the Center for Brackish Water Aquaculture (BBPBAP), Jepara, Central Java, using a completely randomised design with four treatments and three replicates: P0 (ambient pH), P1 (pH 8.25), P2 (pH 8.00), and P3 (pH 7.75). The highest biomass gain occurred at pH 8.25 (P1: 133.47 g), with the greatest specific growth rate also at pH 8.25 (P1: 3.02 % day-¹). The highest chlorophyll a content was observed under ambient pH (P0: 303.61 ± 5.56 mg L-¹). pH significantly affected both growth and chlorophyll a of C. racemosa (ANOVA, P < 0.05). Water-quality variables (dissolved oxygen, temperature, salinity, light intensity, nitrate, and phosphate) remained within ranges suitable for C. racemosa throughout the study.