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Journal of Pharmaceutical and Health Research
Published by Forum Kerjasama Pendidikan TInggi
ISSN : -     EISSN : 27210715     DOI : https://doi.org/10.47065/jharma.v3i1.1322
Core Subject : Health,
Health Professions Medicine & Pharmacology Nursing Public Health
Journal of Pharmaceutical and Health Research memiliki bidang kajian, yaitu: 1. Bidang Gizi Klinis 2. Bidang Gizi Masyarakat 3. Pangan dan Gizi 4. Inovasi Pangan 5. Hematologi 6. Parasitologi 7. Biokimia 8. Laboratorium Kesehatan 9. Teknologi Laboratorium 10. Farmakologi 11. Farmasi 12. Keperawatan Jiwa 13. Keperawatan Anak 14. Keperawatan Maternitas 15. Keperawatan Medikal Bedah 16. Keperawatan Keluarga 17. Keperawatan Komunitas 18. Kesehatan Masyarakat 19. Teknologi Kesehatan
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 31 Documents
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Search results for , issue "Vol 4 No 1 (2023): February 2023" : 31 Documents clear
Formulasi dan Evaluasi Emulgel Ekstrak Rimpang Jeringau (Acorus calamus L.) sebagai anti-acne Rusdiati Helmidanora; Yullia Sukawaty; Husnul Warnida
Journal of Pharmaceutical and Health Research Vol 4 No 1 (2023): February 2023
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v4i1.2894

Abstract

Dermatology studies in Indonesia show an increase in acne vulgaris incidents with the highest prevalence in adolescents. Acne topical therapy generally contains retinoids. However, this therapeutic option has drawbacks, namely burning sensation, dry skin, erythema, and itching of the skin. Along with people's interest in using natural products, alternative therapies with natural products are increasingly having economic value. One of the natural ingredients that have the potential to be anti-acne is Acorus calamus L. Sweet pea (Acorus calamus L.) is a plant whose leaves and rhizomes are used empirically by the Dayak tribe in Borneo to treat skin diseases. Acorus calamus rhizome ethanol extract can inhibit the growth of Propionibacterium acnes bacteria that predominate in acne inflammation. Acorus calamus rhizome extract in this study was formulated in the form of an emulgel because it effectively delivers hydrophobic active substances. Emulgel is also not greasy but moisturizes the skin. The research aimed to produce an anti-acne emulgel formulation from Acorus calamus extract as a natural raw material that meets the physical stability requirements. The research was conducted at the Phytochemical Laboratory, Pharmaceutical Technology Laboratory, and Microbiology Laboratory of Samarinda School of Health Sciences. The research stages are the preparation of plant extract, phytochemical analysis, preparation of emulgel, evaluation of emulgel, and antibacterial activity assay. The Emulgel formulation was carried out with variations in the concentration of the gelling agent, namely Carbomer 940 0.5% (Formula A), 0.75% (Formula B0, and 1% (Formula C). The results of the physical evaluation showed all formulas met the requirements of the organoleptic test, homogeneity test, pH test, spreadability test, and viscosity test. All formulas have non-Newtonian flow types with plastic properties. The antibacterial test results show that all formulas can inhibit the growth of Propionibacterium acnes bacteria.
Persepsi Kepuasan Pasien BPJS Kesehatan dan Dimensi Kualitas Pelayanan Rumah Sakit Umum Daerah Momen Amalia; Christa Bernadeth Ina Tulit; Nursapriani Nursapriani
Journal of Pharmaceutical and Health Research Vol 4 No 1 (2023): February 2023
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v4i1.3028

Abstract

Health service satisfaction is determined by the perception or performance of services in meeting patient expectations. The purpose of this study was to determine the effect of BPJS Kesehatan patients perception on patient satisfaction based on the dimensions of service quality at Labuang Baji Hospital. This research uses quantitative methods with a Cross Sectional Study design. The sample of this study was BPJS Health Patients at Labuang Baji Hospital totaling 87 respondents. Data analysis using Chi-Square test. The results of this study indicate that there is an influence between BPJS Health patient perceptions of patient satisfaction based on the responsiveness dimension with p value 0.001< 0.05, reliability p value 0.002 < 0.05, assurance p value 0.008 < 0.05, empathy p value 0.002 < 0.05. On the tangible dimension thereis no significant effect on patient satisfaction with a p value of 0.064 > 0.05. The variable that has the greatest influence on patient satisfaction is the responsiveness dimension with a p value (sig) of 0.001 < 0.05. The results of this study are the dimensions of responsiveness, reliability, assurance, empathy are variable that have an influence on patient satisfaction while tangible have no effect on patient satisfaction at Labuang Baji Hospital. It is suggested to the RSUD Labuang Baji to improve the quality of service and get a good perception from the patient.
Hubungan Kualitas Tidur Dengan Kadar Glukosa Darah Sewaktu Pada Pasien Diabetes Melitus Tipe 2 Muhamad Sasiar Tajiwalar; I Gede Angga Adnyana; Made Rika Anastasia Pratiwi
Journal of Pharmaceutical and Health Research Vol 4 No 1 (2023): February 2023
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v4i1.3029

Abstract

Background: Disturbances in the quantity and quality of sleep will trigger impaired glucose tolerance and reduce insulin sensitivity, affecting blood glucose levels. This situation can worsen the condition of people with type 2 Diabetes Mellitus. Objective: To determine the relationship between sleep quality and blood glucose levels in patients with type 2 diabetes mellitus at the Praya Public Health Center. Research method: Analytical research uses an observational approach with a cross sectional research design. The sample used was type 2 Diabetes Mellitus patients totaling 181 people taken by purposive sampling technique by measuring blood sugar levels while using the glucotest and providing a Pittsburgh Sleep Quality Index (PSQI) sleep quality questionnaire in data collection. Data were analyzed using spearman's rho. Result: The results of the study of respondents based on blood glucose levels at <200 (89 people) consisted of good sleep quality 96.6% and bad 3.4% while >200 (92 people) with good sleep quality 17.4% and bad 82.6 %. This shows that respondents experience hyperglycemia if the quality of sleep is poor. The analysis using Spearman's rho showed a significant relationship between sleep quality and blood glucose levels (p-value = 0.01) in type 2 Diabetes Mellitus patients at the Praya Health Center. Conclusion: There is a relationship between sleep quality and blood glucose levels in patients with type 2 diabetes mellitus at the Praya Public Health Center.
Pengaruh Pelatihan P3K Terhadap Kemampuan Evakuasi Korban Kecelakaan pada Petugas Parkir Karyo Karyo; Suhartono Suhartono; Kusno Ferianto; Moh. Ubaidillah Faqih; Subianto Subianto
Journal of Pharmaceutical and Health Research Vol 4 No 1 (2023): February 2023
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v4i1.3152

Abstract

Evacuation is the transfer of a person or occupant from a dangerous place to a safer place. The purpose of the study was to determine the effect of First Aid Training on the Evacuation Ability of Accident Victims in Parking Officers in Tuban District. To find out the effect of first aid training on the possibility of accident victims at parking attendants in Tuban District. Metode dalam penelitian ini adalah Pra-Eksperimental (one-group pre-post test design). Cara pengambilan sampel menggunakan simple random sampling, dengan jumlah 19 responden. Instrumen yang digunakan SOP dan lembar observasi. Analisis data menggunakan uji statistik Wilcoxon. There is an Effect of First Aid Training on Victim Evacuation Ability Accident to Parking Officers in Tuban District.
Hubungan Pengetahuan Ibu tentang Keluarga Sadar Gizi dengan Status Gizi Anak Pra Sekolah Erna Rahmawati; Anggraini Dyah Setiyarini
Journal of Pharmaceutical and Health Research Vol 4 No 1 (2023): February 2023
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v4i1.3155

Abstract

Family knowledge especially mothers about nutrition awareness with nutritional status in pre-school children is very important to improve nutritional status. Pre-school children are at an age that is vulnerable to nutritional problems. This study aims to find the relationship between mothers' knowledge about nutrition-aware families and the nutritional status of pre-school children in Karangrejo Village, Tulungagung District. This type of research is a correlational study and based on time it is categorized as cross-sectional. The variables in this study were knowledge as the independent variable and the nutritional status of pre-school children as the dependent variable. The population of all mothers and pre-school children in Karangrejo village, Tulungagung district, was 106 respondents. Using accidental sampling, the results obtained were a sample size of 42 respondents. The statistical test used in this study was Spearman's rho. The study was conducted on 42 respondents with the results (45.2%) having less knowledge and (21.4%) less nutritional status of pre-school children. Analysis of the relationship between the two variables obtained a p value <α = 0.000 <0.05, meaning that h1 was accepted, meaning that there was a relationship between maternal knowledge about nutrition-aware families and the nutritional status of pre-school children in Karangrejo Village, Tulungagung District. There is a relationship between maternal knowledge and the nutritional status of pre-school children. school. Suggestions in this study are that it is expected to routinely carry out weight checks every month at school in order to monitor the growth and development of pre-school children so that if there is a nutritional disorder they can immediately get the right treatment.
Hidrolisis Pati Kacang Kedelai (Glycine max (L.) Merril) dengan Pengaruh Jenis Katalis Asam Siska Futri Nasution; Lathipah Hannah Lubis; Susilawati Harahap; Azhari Umar Siregar
Journal of Pharmaceutical and Health Research Vol 4 No 1 (2023): February 2023
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v4i1.3187

Abstract

Soybean (Glycine max (L.) Merril) is beneficial for lowering blood sugar, relieving menopausal symptoms and preventing dementia. This study aims to determine the effect of the acid catalyst used on the hydrolysis process of soybean starch (Glycine max (L.) Merril) and to determine the effect of time on the process of hydrolysis process of soybean starch (Glycine max (L.) Merril). There are 3 types of acid catalysts used, namely 0.1 N HCl; H2SO4 0.1N; HNO3 0.1 N. Types of qualitative and quantitative research conducted in the pharmaceutical laboratory of the Institut Teknologi dan Kesehatan Sumatera Utara. The results obtained in this study with 0.1 N HCl acid catalyst type for 4 minutes, 5 minutes, 6 minutes, and 7 minutes obtained successive volumes of 15 mL, 21 mL, 18 mL, and 9 mL. 0.1 N H2SO4 catalyst for 4 minutes, 5 minutes, 6 minutes, and 7 minutes, the volumes obtained were 22 mL, 20 mL, 17 mL, and 14 mL, respectively. 0.1 N HNO3 catalyst for 4 minutes, 5 minutes, 6 minutes, and 7 minutes, the volumes obtained were 24 mL, 20 mL, 17 mL, and 13 mL, respectively. From the research results, we can find out the optimal volume produced in 7 minutes with 0.1 N HCl acid catalyst. The longer the time used for hydrolysis process in soybean starch (Glycine max (L.) Merril), the smaller the average volume produced.
Ekstrak Jeruk Nipis Sebagai Obat Terapi Penyembuhan Penyakit Gastritis dengan metode GC-MS Khairul Pahmi Rahmawati; Diah Miftahul Aini; Winda Harnianti
Journal of Pharmaceutical and Health Research Vol 4 No 1 (2023): February 2023
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v4i1.3253

Abstract

Gerd or comonly known as gastritis deseas occure due to inflamation of the gastric mucosa. Drug consumption is no longer safe for the reason of side effect for long term ingestion. Thus, herbal medicine is starting become an option, by employing lime juice for medication or theraphy. Previous study indicated positive response of lime extract for medication on mice. However, the mechanism is yet to be discovered. This study aims to determine the chemical compounds contained in lime extract that responsible for antiulcer activity. The research was carried out in laboratory experimental method, by phytochemical screening than continued by GC-MS. The result shows that lime juice containaing secondary metabolits, namely alkaloid, glycosides, triterpenoid, saponin, polyphenol, flavonoid and phenol that act as an anty-oxidants as well as inductors for formation of stemp cell. Furthermore, GC-MS analysis showed that the presence of citric acid derivatives in the form of citraconic anhindrat, itaconic anhindrat and Itaconic acid, last but not least palmitic acid as part of fatty acid. Citric acid is a compound that has a cappability to be a buffer solution. Therefore, consuming lime juice for gerd medication will help neutralised acidity of the gastric with the principle of buffer solution.
Hubungan Pekerjaan Orang Tua dan Asi Eksklusif dengan Kejadian Stunting Di Menawi Kabupaten Kepulauan Yapen Lindawati Lindawati; Alprida Harahap; Anto Anto
Journal of Pharmaceutical and Health Research Vol 4 No 1 (2023): February 2023
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v4i1.3254

Abstract

Indonesia has a fairly severe nutritional problem, which is marked by the many cases of stunting in children under five. This study aims to analyze social relations. Demographics and behavior of nutrition-aware families and the incidence of stunting in the working area of the Menawi Nursing Health Center, Yapen Islands District This is an observational study with a cross-sectional approach.The population is all families with 242 toddlers and a sample of 149 toddlers in the Menawi Nursing Health Center, Yapen Islands Regency, using purposive sampling and statistical tests using chi-square and logistic regression. The research results showed that occupation (p = 0.018), contact with other cultures (p = 0.001), exclusive breastfeeding (p = 0.001), consumption of diverse foods (p = 0.001), and family behavior aware of nutrition (p = 0.001) were variables related to stunting, while education (p = 0.394) and income (p = 0.646) were not related to stunting. In addition, the behavior of the family that is aware of nutrition has the most influence on the incidence of stunting, with a value of Exp (B) = 3.884. The conclusion obtained is that work, contact with other cultures, exclusive breastfeeding, consumption of a variety of foods, and family behavior that is aware of nutrition are factors that cause stunting. So that sustainable health interventions are needed in the form of family nutrition education.
Kandungan Fitokimia dan Aktivitas Antioksidan Tanaman Waru (Hibiscus tiliaceus L.) Farendina Suarantika; Vinda Maharani Patricia
Journal of Pharmaceutical and Health Research Vol 4 No 1 (2023): February 2023
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v4i1.3093

Abstract

The mangrove plant (Hibiscus tiliaceus L.) is widely cultivated in tropical regions such as Indonesia because almost all parts of plant are believed to provide many benefits. Som of the benefits of the mangrove plant include laxative, treating earache, antibacterial, and antioxidant. The aim of the research is to analyze the content of phytochemical compounds contained in the mangrove plant and its antioxidant activity. This research uses a journal review method based on data collection carried out by inclusion and exclusion obtained from the google scholar, science direct, taylor and francis, garuda, and sage publication data search engine, including textbooks and scientific articles published above year of 2013. The result of the research is the phytochemical compounds found in mangrove plant are anthocyanin compounds, amides, coumarins, phenols, organic acids and flavonoid compounds that identified in the leaves, stems, and bark in mangrove plants uses several of solvents, there are methanol water, chloroform, and ethanol. The part of the plant that has antioxidant activity is the leaves which has strong antioxidant activity (IC50 = 86,5 µg/mL).
Potensi Mikroenkapsulasi Ekstrak Daun Stevia Rebaudiana Terhadap Kadar Trigliserida Tikus Putih Jantan Galur Wistar Hiperlipidemia Mutmainah Mutmainah; I Kadek Bagiana; Ika Puspitaningrum; Lia Kusmita; Yani Kresnawati
Journal of Pharmaceutical and Health Research Vol 4 No 1 (2023): February 2023
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v4i1.3297

Abstract

Coronary heart disease is a cardiovascular disease caused by atherosclerosis. Hyperlipidemia is known as a risk factor for atherosclerosis. The Stevia rebaudiana Bertoni plant is a plant that is efficacious as a hypolipidemic. This study aims to determine the effect of microencapsulated preparations of Stevia rebaudiana Bertoni leaf extract on triglyceride levels in male Wistar rats. One way to improve the formulation is by using the encapsulation process. The encapsulants used are inulin and chitosan. This research was conducted with the aim of making hyperlipidemic rats induced by alloxan at a dose of 150 mg/KgBW rats intraperitoneally. Hyperlipidemic rats were given microencapsulated Stevia rebaudiana Bertoni leaf extract at different dose levels (100, 300, 700, and 1000 mg/kg BW) for 8 weeks; control mice were fed a basal diet during this period. The results of the study concluded that microencapsulation of Stevia rebaudiana Bertoni leaf extract had the potential to reduce triglyceride levels in hyperlipidemic male Wistar rats.

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