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INDONESIA
Indian Journal of Forensic Medicine & Toxicology
Published by Official Organ of Indian Association of Medico-Legal Expert
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Public Health
Arjuna Subject : Kedokteran - Epidemilogi
Articles 5,497 Documents
 150   151   152   153   154 
Impact of Local Anesthesia on Wound Healing Maha T. Al-Saffar1 , Abdulsattar Salim Mahmood2 , Mohammed Salih Sulaiman3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.11817

Abstract

Different local anesthetics produce multiple effects on wound healing, although this effect did notdemonestrated clearly in experimental study. This study aimedto evaluate the effects of several localanesthetics (lidocaine, articaine, mepivacaine) on healing of oral mucosal wound healing in experimentalrabbits by histological examination.The study was conducted on eight healthy adult male New Zealandwhite rabbits which divided into four group(n=2) control group which received no treatment group two(received lidocaine 2% with adrenalin) group three (received mepivacaine) and group four (receivedarticaine 4%). oral mucosal wound were initiated experimentally in all group and each group received theirtreatment by local application one time daily for six day(except control group) in the third day half of theanimal were sacrificed in each group and histological examination for the wound area were conducted , theremaining animal were sacrificed in the sixth day of treatment and histological examination were made forthe wound area to compare the result between the four group. The mepivacaine group produce better result(enhance healing of the oral mucosal wound) followed by atricaine and lidocaine group compared withcontrol one. This study showed that different type of local anesthesia produces different effects on woundhealing manufisted histologically and clinically.
Pharmacological Study of Weight Losing of Liraglutide Loaded within Layered Double Hydroxide Carrier Sevan A. Dushan1 , Ashuor H. Dawood 2, Mustafa G. Alabassi3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.11818

Abstract

The anti-diabetic drug liraglutide was loaded within LDH nanoparticles using the Fe+3, Al+3, Fe+2 and Ni+2ions, the preparation of LDH was carried out via the titration of 2M of NaOH with trivalent and divalent ionsin presence 0.5M HCl, the prepared compounds of liraglutide with LDH were tasted with selective groupsof rats.The compounds were characterized with Fourier transform infra-red (FTIR), X-ray diffraction (XRD),Atomic force microscopy (AFM), Zeta potential and Scanning electron microscopy (SEM).The animals that injected with weekly dose of the prepared compounds shows the weight reductioncomparative with that of the animals injected daily dose of pure liraglutide.
Synthesis and Study the Biological Activity of New Heterocyclic Compounds Derived From Hydrazide Derivatives Wasan M. Abd-AL Hameed1 , Jumbad H. Tomma2, Rajaa K. Baker3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.11819

Abstract

The work involves synthesis of new compounds derived from 2-substituted-3-thio- acetohydrazide1,2,4-triazin. The subsituted hydrazine thiocarbothioamide [IV] was obtained via reaction of hydrazidecompound [III] with ammonium thiocyanate and HCl. The cyclization of compound [IV] in 4% NaOH ledto formation 1,2,4-triazoles [V], which were refluxed with chloro-ethylacetate in ethanol and sodium acetateto give compound [VI]. Condensation of ester-compound [VI] with hydrazine (80%) led to formation newhydrazide compounds [VII]. Ring closure reaction of compound [VII] with 4-aminbenzoic acid in POCl3give 1,3,4-oxadiazoles [VIII]. Compound [VIII] wasreacted with sub. benzaldehyde to form compounds ofSchiff bases [IX]a-d. The synthesized compounds were diagnosed via IR, Mass and 1HNMR spectral data.Many of synthesized compounds were examined against activity of antibacterial: gram (+) (Bacillus subtitis,staphylococcus aureus) and gram (-): (E.coli bacteria) and candida tropicalis fungial. To ensure the safety ofthe synthesis compounds the toxicity was examined.
Role of Selective Cytokines in the Pathophysiology of Patients with Celiac Disease Murtadha M. Jawad1 , Ahmed Abbas Hasan1 , Hassan A. Farman2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.11820

Abstract

Background and Aims: Inflammatory cytokines levels may be elevated in patients with celiac disease(CD). But little known about the association of these cytokines and some immunological parameters usedfor diagnosis of celiac disease. This study aimed to evaluate the levels of some inflammatory cytokines inpatients with celiac disease and compare it with healthy individuals and then their association with someimmunological markers used for diagnosis of celiac disease.Methods: A total of 60 patients with celiac disease and 40 healthy persons were enrolled in 2019. Thelevels of Anti-tissue transglutaminase levels were measured for patients and healthy groups, also Tumornecrosis factor Alpha (TNF-?), Interleukin-6 (IL-6) and Interleukin-8 (IL-8) were measured using enzymelinked immunosorbent assay techniques. Then compare these parameters between groups and the correlationbetween these parameters were assessed.Results: The mean levels of Tumor necrosis factor Alpha (TNF-?), Interleukin-6 (IL-6) and Interleukin-8(IL-8) give a highly significant difference between patients and healthy groups. Anti-tissue transglutaminaselevels correlated and were show statistically significant with these cytokines.Conclusions: TNF-?, IL-6 and IL-8 play a role in the pathophysiology of celiac disease.
Association between Vitamin D Receptor Gene Foki Polymorphism and Gestational Diabetes Mellitus among Iraqi Pregnant Women Raya Hatem Al-Mawla1 , Hameed Hussein Ali2 , Wajeeh Younis Al-Ani2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.11821

Abstract

This study was conducted to evaluate the association between vitamin D receptor gene FokI polymorphismand gestational diabetes Mellitus (GDM) among Iraqi pregnant women.This study included 40 women with GDM, 30 pregnant women without GDM, and 30 non-pregnant womenas a negative control. Age (years), body mass index (BMI), Fasting Blood Glucose (FBG), total cholesterol,triglycerides (TG), and lipid profile of the patients and control groups were compared (Table 1). DNAsampling was purified and amplified by using PCR. The FokI genotype was evaluated using restrictionfragment length polymorphism (RFLP).The results revealed that the age, BMI, FBG, HbAIc, insulin hormone, insulin resistance, and lipid profileexcept HDL-C were significantly increased with an increased GDM risk compared to women with normalpregnancies. In contrast, no significant alterations were observed in concentrations of IGF1 hormone,vitamin D and FokI (F and f) alleles frequency between GDM and control groups.This study suggests that there was no significant correlation between the VDR FokI polymorphism andGDM patients among Iraqi pregnant women.
Using Paper Waste and Local Bacterial Isolates to Produce Biomass and Cellulase Enzyme- A Study Waste Recycling Suhad Dali Abd –Al Hussien1 , Dhafer Fakri Alrawi2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.11822

Abstract

The study aims to isolate the cellulose-degradation bacteria that produce the cellulase enzyme as well as theproduction of SCP protein from Ramadi city soils and to obtain efficient local bacterial isolates in productionand efficient isolation was selected in the production of cellulase enzyme and single cell protein which isBacillus subtillis bacteria tested the efficiency of the isolated isolation to produce the enzyme and single cellprotein. The cell using local media contains the paper waste available in the environment and contaminatedwith it. Initial transactions were made for this paper waste and these factors included (heating to boilingpoint, dilute sulfuric acid and dilute sodium hydroxide). The paper waste used included the white cardboard,yellow cardboard and white paper Which was used as a single source of carbon and energy, after testingthe waste paper used, it was found that the white cardboard treated with heating gave the best production ofthe cellulase enzyme and single-cell protein. The bacterial isolation used showed the best growth and gavethe highest production of the enzyme and the single cell protein at pH 7, while the best temperature for theproduction of the enzyme was 45 ° C. The optimum temperature for the production of the single cell proteinwas 40 ° C. As for the carbon concentration, which is the white cardboard treated with heating, it was betterto produce than Concentration is 2%. As for the production of single cell protein, the highest output atconcentration was 4%. The best bacterial vaccine size for enzyme production was 3 ml / 100 ml medium. Asfor the production of single cell protein, the size of the inoculum gave 1.5 ml / 100 ml the best production.The addition of the organic nitrogen source (urea) gave a clear increase in enzyme production and singlecell protein, and when adding 0.5 g urea / 100 mL medium. Finally, the results showed that the best periodduration to obtain the highest cellulase enzyme production was after 96 hours, while it was found that thebest production of single-cell protein was after 24 hours incubation.
Effect of Foliar Application with Nano-Organic Fertilizer and Proline Acid and their Interaction in Leaf Content of Antioxidants and Vitamin D3 for Moringa oleifera Faten Khalifa Kareem1 , Mahmood A. Al Shaheen2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.11823

Abstract

A potted pot capacity 15 kg experiment was carried out during the agricultural season 2019 in one of theprivate nurseries of Al-Ramadi / Anbar Governorate, to study the effect of foliar application of nano-fertilizerand proline acid on the content of antioxidants and vitamin D3 for Moringa oleifera leaves using sandy mixsoil. The experiment was designed using Completely Randomized Design (CRD) with three replications. Thestudy included three concentrations of nano-organic fertilizer (0, 50, 100) mg-liter-1 and three concentrationsof the amino acid proline (0, 100, 200) mg-1 . after 150 days from the date of seed germination the leafcontent of vitamin C was measured and phenols using the least significant difference LSD at 0.05 probabilitylevel. Qurcetine flavonoids, Rutine flavonoids and vitamin D3 were measured according to the T test totest the differences between the averages of the treatments. The results showed that the nano-fertilizer atconcentration100 mg L1 achieved the highest antioxidant level that included vitamin C, phenol, flavonoidquercetin, flavonoid routine and achieved the highest average vitamin D3 content. And that treatment withproline acid at a concentration of 200 mg / L -1 achieved the highest antioxidant content (vitamin C, phenols,Qurcetine and Rutine flavonoids) in addition to vitamin D3. The interaction between the study two factorshad a positive effect on most of the rates of the studied traits. The plants which treated with (100 mg-liter-1nano organic fertilizer and 200 mg-liter-1-proline acid) gave the highest rate of leaf content of vitamin C,phenols, Qurcetine, and Rutine flavonoids, while treatment with ( 100 mg-liter-1 nano organic fertilizer and100 mg-1-proline acid) has achieved the highest leaf content level of vitamin D3 .
Factors Affecting Success of Corneal Grafting : An Observational Study Saif Al-Shamarti
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.11824

Abstract

This is an observational study of 32 corneal implantation cases performed by the researcher. It shows thatYounger patients (below 60 years) show more improvement. Female patients show more improvement.Corneal dystrophy cases show more improvement followed by Keratoconus followed lastly bullouskeratopathy. Donors aged below 60 years give results that are more positive. There are mild results that aremore positive if the time between death and transplant is less than 5 days. Trephine size more than 7.5MMshows more improvement. Punch size of 8.25MM shows most improvement. Using General anesthesiashows more improvement
Estimation of Some Hormones Levels and Insulin Resistance in Some Infertile Men in Samarra City Aseel Mokdad Hatam AbdulWahed1 , Mostafa Ali Abdulrahman2 , Mahmood I. M. Alkanaani1 , Atheer N. B.
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.11825

Abstract

The study aimed to evaluate levels of some hormones and insulin resistance in infertile men in Samarra city.The study group include 25 infertile men and control group of 10 healthy men. The hormonal and biochemicalassays include testosterone, E2, insulin, IR and fasting blood sugar (FBS). The results was a significantincrease at (P?0.05) in E2 and FBS concentrations, while testosterone show significant decrease at (P?0.05)in infertile men compared to control group. Insulin and IR didn’t show any significant difference betweenboth groups.
Evaluation the Relationship between Oral Contraceptives Containing Drospirenone with Dyslipidemia and Risk of Cardiovascular Diseases among Women in Al-kut City Haider Hafudh Humaish1 , Amer Alasadi2 ,Intithar Aldafae3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.11827

Abstract

Chronic and prolong use of oral contraceptives (OCs) may lead to appearance of undesirable effects inwomen who used these drugs. There are many types of contraceptives, some contain estrogen and the othercontain progesterone, or combination of them in the same drug. This work was performed in a population ofadult females to study the relationship between the chronic use of OCs with dyslipidemia and the threat ofcardiac diseases. A total 163 volunteers were participated in this study, and, their aged between 21-42 yearsold. In addition, all women were free of heart disease, dyslipidemia and any hormonal disturbance accordingto their health records. They were categorized into three differnt groups, the control group included 52unmarried women and does not use any OCs, group A: included 57 women took OCs (combination pillestrogen and progestin) for less than 6 months, and group B contained 54 women used OCs for more than oneyear. We meassued lipid profile, and blood indices of cardiovascular disease, like Creatine Kinase-MB (CKMB), insulin, Lactate Dehydrogenase (LDH) albumin, leptin and HbA1c test. In addition, we determined thecoronary risk index, atherogenic Coefficient, and an atherogenic index . Our results recorded a significantincrease in total cholesterol, LDL, coronary risk index (TC/HDL), LDH and HbA1c in group2 comparedto compared to control group. Furthermore, our data demonstrated no clear differences in Triglyceride,leptin hormone, TG, HDL, insulin, albumin and CK-MB in group2 compared to control. Moreover, thedata indicated a significant elevation in the concentration of leptin hormone, LDH, HbA1c, TC, TG, LDL,coronary risk index , atherogenic Coefficient and Atherogenic index, and significant decline in HDL andalbumin in group B compared with control group. Therefore, we concluded that oral contraceptive coulddeter the lipid profile status and some enzyme related to the cardiovascular system. These alterations conveya possible risk for the development of cardiac diseases. Routine screeing of lipid tests would be measured inwomen used OCs for long periods to avoid any potential risk of cardiac diseases.

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