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INDONESIA
Indian Journal of Forensic Medicine & Toxicology
Published by Official Organ of Indian Association of Medico-Legal Expert
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Public Health
Arjuna Subject : Kedokteran - Epidemilogi
Articles 5,497 Documents
 148   149   150   151   152 
The Synergistic Effect of Combining Some Antibiotics with Powder of Silver NPs, Copper NPs and Titanium NPs Raghad N. Shihab1 , Ali M. Al-Dahbi2 , Saif Ali Mohammed Hussein3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.11795

Abstract

Routine antibiotics susceptibility testing still relies on standardized cultivation-based analyses, includingmeasurement of inhibition zones in conventional agar diffusion tests.The sensitivity of the bacterial isolatescausing Clinical isolatest results showed that all the isolates subjected to this study showed varying resistanceto the antibiotics used. The effect of nanoparticles combined with different antibiotics was investigatedagainst multi resistant Clinical isolates bacteria using disk diffusion method. The inhibition zones diameter(mm) around various antibiotic discs (Trimethoprim, sulphamethaxazol, Azithromycin, Aztreonam,Ceftriaxone, Gentamycin, Tetracyclin, Nitrofurantoin) with/without nanopatrticles against isolates weremeasured. The antibacterial activities of some antibiotics have been increased in the presence of nanoparticleagainst all isolates while others showed no effect. The highest antibacterial activities of antibiotics combinedwith nanoparticle were observed against E.coli isolates for Gentamycin, Trimethoprim-sulphamethaxazol,Azithromycin ,Tetracyclin ,Nitrofurantoin. while A. baumanii appeared sensitive to Gentamycin,Trimethoprim sulphamethaxazol and Azithromycin compared with antibiotics alone. K.pneumoniae becamesensitive to Gentamycin, Tetracyclin and P.aeruginosa to Ampicillin,Trimethoprim sulphamethaxazol,Azithromycin and Gentamycin. nanoparticle showed no effect on antibacterial activities of all antibioticsexcept Gentamycin against gram positive bacteria S.aureus.
Phylogenetic Tree Analysis of First Psychrobacter Sp. Strain From Blood of Iraqi Patient; A Case Report Nuha S. Jassim1 , Sameer Abdul Ameer Alash2 , Najwa Shihab Ahmed2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.11796

Abstract

Psychrobacter spp. are a Gram negative bacteria, aerobic, non-motile, small, with coccobacilli shape.Originally isolated from seaweed samples and marine environments. Recently considered as rareopportunistic human pathogens. Sixty –five years old women admitted to hospital with diabetic mellitusand stage 4 pressure ulcers (PU) with seizure and mild fever 37.9 °C. A gram staining of blood culturerevealed gram negative bacteria have a cocobacilli shape. The VITEK2 system (bioMérieux) misidentify theisolate as Acinetobacter bumannii complex with low discrimination. The submission of the bacterial isolateto the GenBank BLAST search tool revealed that the Iraqi isolate show 100% homology with Psychrobactersp. From china with accession number ID: MK205167.1, the next matches with Uncultured Psychrobactersp. ( ID: KF859544.1 China) Psychrobacter pulmonis(ID: KU364058.1, India), Psychrobacter pulmonis(ID: MH550129.1, China)with 99% similarity for each one. This Psychrobacter sp. was the first isolate frombacteremia patients in Iraq. The identification based on 16S rRNA gene sequence for precisely identify thisbacteria that misidentified by VITEK2 system
Analytical Evaluation Study of Some Characterization of Potable water for an Old Well in Baghdad City Analytical Evaluation Study of Some Characterization of Potable water for an Old Well in Baghdad Cit
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.11797

Abstract

This study involved measuring seventieth tests five of its physically ,temperature, color, turbidity, electricalconductivity and pH and remaining tests were chemical ten of them for heavy metals ,the chlorine and fluorinewere also investigated for water of old well in Baghdad city close to tiger river weekly for six months ,thisstudy showed validity of this well to drink and domestic use within the limit of the properties and elementsstudied only ,through the tests ,all the samples were found to be transparent and non-colored ,there wasnothing left after her leaving ,and the pH ranged from (7.655-7.920) , conductivity (821-908µsemens/cm)and temperature (19.68-23.36ºC) ,the concentrations of elements were (0.031-0.044), (0.038-0,053), (0.009-0.015), (0.019-0.025), (0.004-0.006), (0.009-0.011), (0.029-0.035), (0.108-0.112) ,(0.003-0.005), (95-111),and (0.424-0.571) µg/ml for lead ,cadmium, iron, copper, antimony, cobalt, chromium, zinc, manganese,chlorine and fluorine respectively ,as for nickel, it is not registered, all the tests have been subject to the localand international standards except lead and cadmium, according to international standard only
Prevalence of Hepatitis B, C and HIV Viruses among Hemophiliac Patients in Al-Anbar Governorate Hussein Ali AL-Enzy1 Fakhri Jamil Al-Dalla Ali2 , Adnan M Jasim3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.11798

Abstract

Background: People with hemophilia (factor VIII and IX deficiency) and those with other clotting factordeficiencies are particularly at risk of acquiring blood-borne hepatitis virus infections and HIV throughtransfusion with unscreened blood and blood products.Objective: To estimate the prevalence of hepatitis B, C, and HIV among hemophiliac patients in the AlAnbar governorate.Patients and methods: A cross-sectional study carried out between October 2014 and March 2015 wasdone to estimate the prevalence of hepatitis B, C, and HIV among hemophiliac patients. Forty hemophiliacpatients were recruited to this study, who were documented to have hemophilia A and B by factor assay.Patients’ surveillance for hepatitis B, C and HIV were done by the electrochemiluminescence immunoassay“ECLIA” by using Cobas e 411-immunoassay analyzer.Results: Forty hemophiliac patients with age ranged between 6 months and 22 years with mean age 9.9 ±5.4 years were recruited to this study, 5 patients were mild hemophilia, 6 patients moderate hemophilia and29 patients with severe hemophilia.The prevalence of hepatitis C among the 40 hemophiliac patients was 5%, while for hepatitis B and HIV was0%. Six patients (15%) showed immunity to hepatitis B due to successful vaccination.Conclusions: This study showed that the prevalence of hepatitis B and HIV is zero, while for hepatitis C5%. Hepatitis C infection was more in severe hemophilia A, advanced age and an increasing number ofblood and blood products transfusion. Only 6 patients (15%) among hemophiliac patients were seropositivefor hepatitis B vaccine immunity.
Quantitative Genetics Analysis of Autism According to Sex Hormones A-S. U. Hassan1 , Najat Mohammed Flyyih2, Suhaib Khalid Ibrahim3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.11799

Abstract

The present paper applied the light on 46 rats models induced with autism to prove the relationship amongsex hormones and both of aromatase and RORA. After six practical steps, the results explain a negativerelation of testosterone opposites with positive one for estrogen for their relations on aromatase andRORA. As testosterone rise significantly 3.015±0.321 ng/mL, estrogen declined significantly too to record0.033±0.0011 ng/mL. on the quantitative genetic levels we concluded that both sex hormones affecting thephysiological mechanisms of aromatase reaction and RORA synthesis.
Association Between Carbamazepine Toxicity, Liver Bile Duct Injury, Granuloma and Inflammatory Cells Infiltration in Female Mice A.T. Nawar R. Jaber1 , Nahla A. Al-Bakri2 , A.T. Ola Al-Bhadly3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.11800

Abstract

The liver is an important organ in the body that can be affected by many drugs and toxins. The hepatotoxinscan cause oxidant stress that lead to activation of inflammatory cells and cause liver damage. Drug inducedbile duct injuries are related to drug toxicity, multiple drugs have been known to cause the development ofliver granulomas. Carbamazepine (CBZ) among other antiepileptic drugs is believed to cause hepatic injury.In this study we investigated the effect of (CBZ) 20mg/kg/day on female mice liver after 14 and 30 daysof treatment. The histological findings showed that (CBZ) can cause histological alterations in the livercomponents such as bile duct proliferation, biliary hypertrophy, ductopenia, inflammatory cells infiltrationand granulomas.
A Program for Developing Locally Food Supervision to Support Sanitary Monitoring Work Mahmud Abdullah Jasim Alkhafaji
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.11801

Abstract

Food supervision in Iraq is the responsibility of the Ministry of Health and Environment, which conductsfood supervision to all food establishments worked in Iraq by the department of sanitary monitoring inBaghdad city as well as all directorates of health in Iraqi provinces. As a result of increasing the numberof food businesses national wide in last years, increasing the number of consumers, Iraq’s openness to theinternational market, and using the policy of random import. Due to the mentioned reasons, many problemsrelated to consumer’s health has appeared, this matter pushed the Iraqi Government to establish committees,organized seminars, and workshops related to this subject to resolve problems effected in consumer’shealth. This problem requires more effort from researchers and specialists in food supervision and sanitarymonitoring in Iraq to protect consumer’s health especially from foodborne diseases. The proposed programis the start of the way towards new food safety policy in Iraq and it will be considered as the essential baseof reorganization food control authorities in Iraq and updating national food regulations and legislations.
Synthesis and Biological Activities of New 1,2,3,4- Tetrahydroquinoline Derivatives Using Imino Diels-Alder Reaction Mariam Abdul Jalil Abdul Razak1, Muhammad Abd Kadhum2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.11802

Abstract

This research contains the preparation of some novel derivatives of tetrahydro quinolone. First step, includeprepared new Schiff’s bases compounds (I1-I5) were prepared by the direct condensation between diaminecompounds and aromatic aldehydes substituted by different groups. Tetrahydroquinoline derivativescompounds (I6-I10) were prepared through imino Diels-Alder reaction using the derivatives of Schiff basewith cinnamic acid, and Boron tri fluoride ethyl etherate (BF3.Et2O) as a catalyst. The prepared compoundswere identified by infrared spectra, 1H-NMR, and 13C-NMR. Antibacterial activity of the prepared compoundswas measured by using three pathogenic microorganisms including Staphyloccus haemolyticus, Klebsiellapneumonia,and Candida albicans. Also, a comparative study was achieved to study the biological activityof these prepared compounds using Agar Diffusion method.
Phenotype Detection of Genetic Enzymes B- Lactamase Isolation of Patients with Urinary Tract Infections Bacteria Escherichia Coli Ali Hassoun Hammadi
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.11803

Abstract

Background: the main cause of multidrug resistant bacteria is the production of ?-lactamase enzymes. Theobjective of this study was to determine the prevalence of genotype of Escherichia coli spp. isolated fromnosocomial urinary tract infections (UTI). Methods: In a cross-sectional study from May 2019 to January2020, mid-stream urine specimens were collected from 210 patients presented with acute urinary tractinfections whom attending Al- Shahid Ghazi and Al-Hariri Hospital in Medical City/ Baghdad. Sampleswere cultured for E. coli isolation. Antibiotic sensitivity test and the prevalence of resistance enzymeproducing gen were investigated. Results: A total of 210 E. coli were isolated, multidrug resistance strainof E coli (92.85%) was reported by this study. PCR technique indicated that 88.57% of ESBL-producingisolates possessing blaTEM, 30% blaCTX-M genes and 20.48% blaSHV genes between isolates and E. colistill the less resistant to carbapenem due to low expression of KPC gen. Conclusion: ESBLs and KPC werethe higher prevalent genotype of multidrug resistant E. coli in urine sample.
Immunohistochemical Evaluation of Apoptotic Proteins Expression in Liver and Spleen after Treatment of Cystic Echinococcosis: An Experimental Study Talib Waseen Hussein1 , Waheeda Rasheed Ali1, Haider F. Ghazi2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.11804

Abstract

The cellular immune response and apoptotic pathways are closely related dose dependent responses againstEchinococcus granulosus antigens. The aim of this study is to evaluate the cellular expression of Bax,Bcl-2 and Caspase-3 in both liver and spleen of experimentally cystic echinococcosis mice treated withOxfendazole, Oxfendazole +Praziquantel, Oxfendazole +Albendazole and Albendazole +Praziquantel ofexperimentally mice model of cystic echinococcosis. After 2 months of treatment, mice were sacrificed andboth liver and spleen were processed for immunohistochemistry staining protocol using specific primaryantibody against mouse Bax, Bcl-2 and Caspase-3 proteins. The results showed that E. granulosus infectionable to induce apoptosis in both liver and spleen tissues after induction of cystic echinococcosis mice model,treatment with Albendazole in combination form gives better results because of attenuation of apoptosispathway and restore of normal cellular behavior. In conclusion, this study describes the involvement ofapoptosis in the pathogenesis of cystic echinococcosis.

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