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Prevalence of Reticular Oral Lichen Planus: A Retrospective Study
Sneha Sree.S1 , Jayanth Kumar Vadivel2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd
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DOI: 10.37506/ijfmt.v14i4.12401
Oral lichen planus(OLP) is a common chronic mucocutaneous disorder with an immune mediatedpathogenesis. Etiology of OLP is unknown, but it is thought to be the result of an autoimmune process withan unknown predisposing factor. The clinical presentation of OLP ranges from mild painless white keratoticlesions to painful erosions and ulcerations. It has various oral manifestations with the reticular type beingthe most common. The erosive and atrophic variants are less common but most likely to cause symptoms.Topical corticosteroids constitute the mainstay for symptomatic lesions of OLP. The aim of this study is toinvestigate the prevalence of reticular variant of oral lichen planus.Materials and Methods: In the presentstudy a total of 68 patients were included. The demographic, clinical and treatment details were recorded. Allthe collected data was analyzed by SPSS IBM software Results: Among 63 patients with OLP 60.3% werefemales showing a bilateral involvement in the buccal mucosa (92.1%) with P<0.05. The reticular variantconstituted (37.1 %) of all the total cases and erosive variant was the most common (57.1%).Corticosteroidswere the most common drug. Conclusion:Within the limitations of the study it is evident that OLP has morefemale prevalence, erosive form was more frequent followed by the reticular form of Lichen planus. Buccalmucosa was the most commonly affected site and majority of the patients were treated using Corticosteroids.
Mentor Mentee Strategy in Academic Success -A Review
Rinki Susan George1 , Anitha Roy2 , Lakshmi.T3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd
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DOI: 10.37506/ijfmt.v14i4.12402
Mentor Mentee is a symbiotic relationship which is aimed at advancing academic excellence and careersatisfaction for both mentor mentee equally. Mentors play a vital role in providing emotional and careersupport thereby prominently helpful in the decision making process. They are capable of making diverseconditions for mentees which promotes the level of confidence and leadership equalities in them. Effectivementorship is one of the determinants for academic success.The mentors must be able to create a networkof support for the mentees, and maintain balance to manage the stress through effective communicationwhich will help to facilitate desirable attributes and practices. Mentors must be able to plan, organize,manage meetings and create a schedule for maximizing academic success . The significant mentor menteerelationship is often challenged by increased academic work , managing stress and multiple work at a time.The mentors act as a catalyst for advancing academic ranks, career selection, leadership roles, income andoverall job satisfaction. There must be a need to cultivate an efficient mentoring relationship , chosen fromthe mentees perspective and propose a strategy of managing up to guide the mentees action. Positive mentormentee relationships are pivotal for advancing academic success and career satisfaction.
A Current Review on Gut Microbiota For Healthy Life
Harini B1 , Anitha Roy2 , Lakshmi.T2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd
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DOI: 10.37506/ijfmt.v14i4.12403
The human gastrointestinal tract is highly populated by a vast and diverse community of different microbes.Every individual is provided with a unique gut microbiota which varies according to their food habits anddietary intakes. This human gastrointestinal tract gut microbiota has various functions by participating inhost mechanisms or metabolisms acts as or gives protection against the pathogens invading microbes intothe gut,and also play an important role in facilitating the immune system development and function. Anslight alteration even in this natural flora of gut in the intestine can cause infectious disease and disorders tothe human. Various infections due to antibiotics and gut bacterial communities,bacterial interactions,mooddisorders,metabolic disorders,diabetes,allergic disease,inflammatory bowel disease,hormonal and manyneurological processes can happen. Hence, it is very important in maintaining the natural flora of the gutas it maintains a healthy gut microbiota , structural integrity and protection. Recently ayurvedic medicinesare used over allopathy for its less sides on the body and for maintaining a healthy gut microbiome. Thisreview aims on the current status of the gut microbiota for healthy life under key problems identification andmaintaining the current healthy gut microbiota in the human gastrointestinal tract.
Oncogenes Associated with Oral Cancer - An Update
Nishanthana Murali1 , Vijayashree Priyadharsini J2 , Anitha Roy3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd
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DOI: 10.37506/ijfmt.v14i4.12404
Oral cancer and oropharyngeal cancer represent a large group disorder that falls into the head and neckcategory and is considered as the most leading cause of death in developing countries. The prime reasonfor the high mortality rate of patients suffering from oral cancer is the delay in the diagnosis of the type andgrade of oral cancer and also in the offering of prompt treatment. A report from India demonstrated that 35%of oral squamous carcinoma contains H-ras gene mutations which are an oncogene. Advances in the field ofoncogenes have created an instrument to examine the various phases of carcinogenesis, including progressfrom premalignant to metastatic stages. These systems have direct importance to oral malignancy wherethe precancerous stage is very much characterized. Primer investigations into the articulation and capacityof oncogenes recommend anomalies including the individual proliferation of at least three kinds of theseoncogenes. Some of the oncogenes associated with oral cancer are studied in this article and the factorscontributing to its molecular basis like chromosome instability and telomerase activity are also discussedbriefly. There are many risk factors and other predisposing factors that may affect the diagnosis, prognosis,and progression of oral cancer and are also discussed in this article.
Safety of Dental Restorative Materials – A Survey among Undergraduate Dental Students
L.Sai Charan1 , Balaji Ganesh S2 , V. Vishnu Priya3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd
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DOI: 10.37506/ijfmt.v14i4.12405
Usage of proper dental restorative materials is very important in dentistry. One who is doing the course ofdentistry should have sound knowledge on these restorative materials. Furthermore, it is important to knowthe view of budding young dentists about safety of dental restorative materials. The aim of present study wasto assess the awareness and perception of undergraduate dental students towards safety of dental restorativematerials. A study was carried out by using multiple-choice structured questionnaire among 262 students,the questionnaire was prepared in such a way that we can assess the attitude, their perception and awarenesstowards safety of dental restorative materials. The data was collected and statistically analysed. Although,most of the participants were having moderate level of awareness towards safety of dental restorativematerials. The level of perception of some respondents towards amalgam related and other restorativematerials related issues was found to be improved, participants with a better perception and attitude arehaving more knowledge and awareness towards safety of dental restorative materials. Within the limitationsof the study, usage of alternative materials to amalgam should be improved.
Coronavirus Disease 2019: Corona Viruses and Blood Safety - A Review
J. Dhayanithi1 , M.P. Brundha2 ,
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd
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DOI: 10.37506/ijfmt.v14i4.12406
The main aim of the study is to understand the current information of corona transmission and bloodsafety measures taken during handling blood safety products of corona infected patients.Coronaviruses arein the subfamily Ortho Coronaviridae of the Coronaviridae family.It is a type of viral virus that causesinflammation in your nose, sinus, or upper throat.Most coronaviruses are not harmful.The virus may resultfrom pneumonia, respiratory failure, septic shock, and death. Many complications of Coronavirus disease2019 (COVID 19) may result from a condition known as cytokine release syndrome or a cytokine storm.This study mainly aims at the awareness and perception of rural and urban people about covid-19 virus..Finding advance in blood safety to avoid blood contamination. It will help to provide a proper diagnosisof the disease and understand current information on coronavirus transmission and blood safety measuresduring the course of the infected patient’s blood safety procedures.To assess public health risks and therisk of occupationally acquired disease which may be associated with the management of infectious waste,understanding these factors is required.The storage, processing and examination of blood specimens fromCovid?19 patients must be carried out by qualified staff in suitably equipped laboratories, previously educatedon the technical and safety procedures.A blood-borne illness is a disease which can spread by blood andother body fluids contamination. Blood can contain various types of pathogens, mainly microorganisms likebacteria and parasites, and non-living infectious agents such as viruses. Through taking preventive steps inthe handling of blood products and storage of blood products for infection, contamination will be reducedand the public will not be affected.
Matrix Metalloproteinases (MMPS) and its Role in Cancers - A Review
J. Aparna1 , M.P. Brundha2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd
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DOI: 10.37506/ijfmt.v14i4.12407
The main aim of this study is to analyze the role of Matrix metalloproteinases genes in cancer progressionand metastasis. Matrix metalloproteinase genes were identified in humans, and many are involved in cancer.Extracellular matrix (ECM) degradation by matrix metalloproteinase not only enhances tumour invasionbut also affects tumour cell behaviour and leads to cancer progression. This review highlights recentdevelopments in the cellular and molecular mechanisms of matrix metalloproteinase that influence tumourcell growth, invasion, and metastasis. A review with recent information about matrix metalloproteinases andits role in cancer collected from search engines from the articles dated from 2000-2020. The recent articlesdiscussed in this review help to gain knowledge and understanding of Matrix metalloproteinases in cancerinvasion and progression, metastasis, angiogenesis, and aid in the analysis of the mutations caused whichaid the medical field to prevent tumour progression.
Role of Lasers in Composite Restorations
Kameswari.S1 , Jayalakshmi Somasundaram2 , Ezhilarasan. D3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd
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DOI: 10.37506/ijfmt.v14i4.12408
The term LASER is an acronym for ‘Light Amplification by the Stimulated Emission of Radiation’. The first laser was introduced in the 1960’s by Miaman. Laser is used to treat a number of various dental conditions like composite restorations etc.. It is most commonly used in restorations for treating hypersensitivity, tooth decay, gum diseases and whitening teeth. Various kinds of lasers such as ND:YAG, Er:YAG, Er:Cr:YSGG are used in various dental procedures. Laser seems to be made for effective removal of dentine and enamel with only minor side effects such as thermal damage. The capability of Er:YAG lasers for the removal of hard tissues in dentistry was exhibited as of now in 1989, Er:YAG (erbium-doped yttrium aluminum garnet) lasers have been progressively utilized in dental practices and are turning out to be increasingly more an agreeable technique for caries evacuation for patients, as conventional cavity drilling may cause noise and pain. Laser received FDA approval for caries removal and cavity preparations. The use of laser therapy also seems to be promising from many recent researchers. Laser therapy induces surface roughness or even improves bond strength or decreases marginal leakage. There seems to be a general consensus on the fact that Er:YAG is one of the best suited types of lasers because it’s efficiency in dentine is very good without any damage of pulp. Er:YAG lasers are a lot utilized in small scale blasts that may bring visible irregularities. In addition, pain reduction in comparison to bur assisted preparation of cavities has been clearly demonstrated.
Use of Urinary Reagent Strips in Testing Cerebrospinal Fluid For Meningitis - A Review
M. Dhakshinya1 , M. P. Brundha2 , Ezhilarasan3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd
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DOI: 10.37506/ijfmt.v14i4.12409
Analysis of cerebrospinal fluid (CSF) is needed to make a meningitis diagnosis to assist in the propermanagement of patients. There is a good correlation between the results of reagent strip test and laboratorymethods of CSF protein, sugar, and leukocyte estimation. CSF supplies nutrients to tissue in the nervoussystem. CSF eliminates waste products from cerebral metabolism. Cerebrospinal fluid has three mainfunctions: CSF protects against trauma on the brain and spinal cord. Meningitis is a rare infection thataffects the delicate membranes called meninges, which cover the brain and spinal cord. Index test wasdone for testing meningitis using urinary reagent strips. An intrusive outpatient procedure used to removea sample of cerebrospinal fluid (CSF) from the spine’s subarachnoid area is a lumbar puncture (LP), alsocalled a spinal tap. A urinary test strip or dipstick is a simple medical tool used in normal urinalysis to assessabnormal differences in a patient’s urine. There is a good correlation between the results of reagent strip testand laboratory methods of CSF protein, sugar, and leukocyte estimation. The review gives a clear view andknowledge about the usage of urinary reagent strips in measuring CSF for meningitis.
Role of Iron Deficiency in Chronic Hair Loss
R. Ananya1 , M. P. Brundha2 , D.Ezhilarasan3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd
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DOI: 10.37506/ijfmt.v14i4.12410
Anemia is a condition in which you lack enough healthy red blood cells to carry sufficient oxygen into thetissues of your body. Anemia can make you feel weak and tired. Iron deficiency anemia is the most commonform of anemia, which occurs when there is not enough mineral iron in your body. To generate hemoglobinyour body needs iron. If your blood supply doesn’t have enough iron, the rest of the body can’t get theamount of oxygen it needs.Hair is a fast-proliferating organ with a high blood supply requirement. Thelength and size of the hair depend on the hair cycle anagen, growth stage. At the center of these systems,however, lies the blood supply in the scalp, the oxygen delivery system, and nutrients that are provided to thesubcutaneous blood flowing hair follicles. It is not yet clear what role iron plays in hair loss. This researchhad the purpose of determining the relationship between iron and hair loss. Iron hair loss deficiency maylook like traditional hair loss patterned by males and females. A study published in the Journal of KoreanMedical Science found that iron may not only play a role in hair loss, but may also cause hair to fall out ina manner similar to genetic baldness of male and female patterns. The aim of the study is to analyse the roleof iron deficiency in chronic hair loss. Most widely cited nutritional causes of hair loss include iron, one ofthe key micronutrients in metabolism of our body. This review gives a clear knowledge about the differentroles played by iron deficiency in the body, specifically its role in chronic hair loss.