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Indian Journal of Forensic Medicine & Toxicology
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Core Subject : Health,
Articles 5,497 Documents
A Resistant Grave’s Disease in Pregnancy: Case Report and Review of the Literature Minal Kalambe (Akare)1 , Mugdha L. Jungari2 , Dipti Shrivastava3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.12742

Abstract

Background: Thyroid hormones are crucial regulators of early development and play an important role inthe maintenance of a normal pregnancy and in the development of the fetus, particularly the fetal brain. Theeffective management of Grave’s Disease (GD) during pregnancy is challenging for the clinician. The mostcommon causes of hyperthyroidism are autoimmune GD and multinodular goiter.A 35 year old lady at 28 weeks of pregnancy, a case of Graves’ disease on anti-thyroid drug with uncontrolledthyrotoxic symptoms despite regular medication didn’t show clinical and biochemical normalizationeven with the maximum dose of antithyroid drug and antihypertensive drug permissible at pregnancy. Atgestational week 28, T4 and T3 remained elevated with suppressed serum TSH and high levels of TSHreceptor antibody levels. The patient had to be followed up medically with guarded prognosis. On follow uppatient didn’t show any clinical or biochemical remission. Despite high thyroid hormones levels and higheranti-TSH receptor antibody levels all throughout the gestation and with maximum dose of PTU the patientdelivered a healthy baby with no clinical symptoms of thyrotoxicosis, goitre or any stigmata of PTU in theneonate. Mother’s TFT was closed monitored and anti-thyroid medication was titred. We present a rare caseof resistant GD in pregnancy, in different stages of pregnancy management encountered many challenges.
Observational Study of Patients Presenting with Bleeding in First Trimester Sonal Nandekar1 , Mugdha Jungari2 , Deepika Dewani3 , Mrunal Nakade4
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.12747

Abstract

Objective: First trimester is an important period during which there is risk of bleeding and may lead tospontaneous abortion. More than 80% spontaneous abortions occur in first trimester. The aim of this studywas to determine the causes of first trimester bleeding.Method: This was a cross sectional descriptive study conducted at Shalinitai Meghe hospital and Researchcentre Hingana, Nagpur during January 2020 to June 2020. The patients presenting to OPD with history ofbleeding or spotting per vaginum, positive urine pregnancy test and less than 12 weeks of gestation wereincluded in this study. Clinical examination and ultrasonography was done.Result: Most of the patients presented with moderate bleeding and associated pain. The duration of bleedingwas 2 to 5 days. Majority of cases were between 4-8 weeks (69.5%). History of prior miscarriage was presentin 23.7%. 61% of cases were anemic. Threatened abortion was most common in patients presenting withbleeding per vaginum (in 47.5%). 18.6% patients were with incomplete abortion and 11.8% had completeabortion. There were 2 cases of unruptured ectopic pregnancy and 1 case of ruptured ectopic pregnancy.Salpingectomy was done in all the 3. Dilatation and evacuation was done in 12 cases. Gestational sac waspresent in 52 cases and the appearance was normal in 53.8% cases. Yolk sac was present in 65.4% cases.Fetal pole and cardiac activity was seen in 57.7%cases.Conclusion: Bleeding in first trimester of pregnancy is the common complaint with which the pregnantwomen presents to the health care worker. The commonest cause is the threatened abortion. Other causesare incomplete, complete and missed abortions. Bleeding in early pregnancy may be early presentation of aserious situation like ectopic pregnancy. Ultrasonography, especially the Trans Vaginal is very important inconcluding the causes of bleeding. Pregnant women should be educated in the first visit to antenatal OPDitself for the symptoms like bleeding per vaginum and to seek help from health care worker as soon aspossible.
The Effect of Eye-Hand Coordination Device on Subjects with Hemiparesis Muzahid K. Sheikh1, Neha Chaudhary2, Parikshit Muley3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.12748

Abstract

“Coordination” the harmonious functioning of interrelated organs and parts, applied especially to the processof the motor apparatus of the brain which provides for the co-working of particular groups of musclesfor the performance of definite adaptive useful response. In Current Clinical Practises there Less DevicesWhich can help in Gaining Eye-Hand Coordination. Objectives: To compare the effect of conventionaltraining approach and eye-hand coordination along with conventional training. Materials and Method: Thesubjects in Datta Meghe College Of Physiotherapy were screened and 42 subjects were divided into 2groups i.e Group A subjects were given Conventional Physiotherapy for coordination training and GroupEye-Hand Coordination Device along with given Conventional Physiotherapy for coordination training.The interpretation of the study was done on the basis of comparing pre-test and post-test assessment of NCTgrading and FMA-UE.Result: Intragroup comparison results showed that NCT grading and FMA-UE scale were statisticallysignificant in both the groups (p<0.0001). Whereas the intergroup comparison results showed that Eye-HandCoordination The device along with Conventional physiotherapy was statistically significant in improvingNCT score (p=0.0021) and FMA-UE score (p=0.0001) than only Conventional Physiotherapy alone forEye-hand In-coordination Conclusion: The Eye-Hand Coordination Device was Significantly effective whenGiven With Conventional Physiotherapy For treating In-coordination and improvement in coordination.Conventional Physiotherapy is also effective in treating in-coordination, but after a certain duration oftreatment, the patient starts getting adapted and chances of achieving the plateau phase
Evaluation of the Effect of Local Application of Kalpit Kasisadi Yogain the Managementof Ksharasutra Induced Hyper Granulation at External Opening Offistula-in-Ano: A Randomized Controlled Trial Prafulla Fadanvis1, Rashmi Gurao2, Dhiraj Zade3, Sonali Wairagade3, Vasant Gawande4, Pradip Adhav5
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.12750

Abstract

Background: The Ksharsutra therapy is most fascinated para surgical process for fistula–in–ano. But duringthe procedure hyper granulations are typically seen near the external opening of fistula which may bleed orget infected if remain untreated. Moreover it may obliterate the pus drainage and thus complicate the wound.This consequence needs to be addressed. In Sushrut Samhita, raised soft tissues of wound is described asUtsanna Mrudu Vrana Maansa and specified to be treated by “Avasadana Dravya” with honey.Aim: To evaluate the effect of LA of Kalpit Kasisadi Yoga with Madhuin management of hyper granulation,found at external opening of fistula-in-ano during its treatment with Ksharsutra.Material and Method: 60 operated cases of fistula-in-ano with Ksharsutra, presenting with hypergranulation at the external opening of fistulous tract were randomly selected and divided into two groups.Observation: The comparison between both the group indicates that effect of the therapy was very significanton thickness while insignificant result was obtained in area of hyper granulation. However the percentage ofrelief in both the criteria’s in experimental group was above 90%.Result: The LA of Kalpit Kasisadi Yoga in the management of Ksharasutra induced hyper granulation atexternal opening of fistula-in-ano is more effective than LA of Madhu alone.
Anesthetic Management of Patients with Sickle Cell Disease Posted for Bipolar Prosthesis Dr. Sweety Agrawal, Dr. Pratibha Deshmukh, Dr Priyanka Deshmukh, Dr Anjali Modak,
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.12751

Abstract

In case of surgical procedures in sickle cell disease (SCD), patients are associated with high risk ofperioperative complications like vaso-occlusive crisis, chest syndrome, post-operative infections, congestiveheart failure, cerebrovascular accident and acute kidney injury. Preoperative assessment and stabilizationlike control of sepsis, blood transfusion, correction of hypoxia, hypothermia, dehydration and acidosis isneeded to reduce peri-operative complications. Blood transfusion (Simple, manual exchange and automatedexchange) remains an important therapeutic intervention in patients with SCD. The case study below showsthe perioperative management of patients posted for bipolar prosthesis due to AVN (avascular necrosis).Adequate analgesia, incentive spirometry, early mobilisation and oxygen supplementation is the mainstayof post-operative management.
Triple Drug Therapy with Proton Pump Inhibitor a Better Option for Helicobacter Pylori Eradication Lamture Y.R.1, Thavendra Jaglal Dihare2, Varsha Gajbhiye3, Gode Dilip4
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.12752

Abstract

Introduction: H. Pylori is a gram-negative micro organism residing in the stomach of human. It is aimportant cause of acid peptic disorders. Bismuth based triple therapy,triple therapy regimens(Tripple PPI)and Quadruple therapy are the available treatment options to eradicate H. pylori. Controversy still presentsregarding the superiority of treatment modality and results of available studies are variable. Hence thisstudy was undertaken to evaluate and compare the efficacy of triple PPI, Quadruple therapy, and bismuthbasedtriple therapy in treating acid peptic disorders and Helicobacter pylori eradication. Method: This studywas a prospective interventional. After the establishment of a clinical diagnosis of the acid peptic disorder,the patient was posted for endoscopy. H. pylori status was determined by the rapid urease test and cultureexamination. All patients divided into three groups and offered three different medical treatments the firstgroup received bismuth bases triple therapy, the second group got Tripple PPI therapy and the third onereceived quadruple therapy. efficacy and comparison of all these treatment modalities were evaluated andassessed by symptoms, endoscopic findings, and results of the rapid urease test after 6 weeks. Results: In thepresent study, 150 patients with upper gastrointestinal symptoms were studied It was found that the maximumnumber of subjects belonged to the age group 31-40 yrs. Male outnumbers than females. Maximum patientshad pain in epigastric region and were having gastritis as a commonest diagnosis., Symptomatic relief byTriple therapy with PPI was maximum than other therapies. Rapid urease test (RUT) was also suggest thattreatment with it gives superior eradication rates. Discussion: In our study, we have found that the treatmentregime with PPI Triple therapy has given maximum symptomatic relief, there is an association of H. Pyloriinfection in an acid peptic disorder like duodenal ulcer (86.66%), gastric ulcer (75%), and gastritis (82.85%).the efficacy of the Rapid urease test is 66% and that of culture is 38.66% in the diagnosis of H. pyloriinfection in acid peptic disorder. Conclusion: PPI Triple therapy is most effective in symptomatic relief andhealing of the duodenal and peptic ulcer
Correlation of Helicobacter Pylori Infection with Acid Peptic Disorders Thavendra Jaglal Dihare1, Lamture Yashwant R.2, Varsha Gajbhiye3, Gode Dilip4
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.12753

Abstract

Introduction: The acid peptic disorder is a disorder in which due to hyperacidity, there is the damage ofinner lining (mucosa) of the stomach and duodenum causing various manifestations like inflammation,ulcer, etc. The acid peptic disorder is a disorder in which due to hyperacidity, there is the damage of innerlining (mucosa) of the stomach and duodenum causing various manifestations like inflammation, ulcer, etc.A major symptom of the acid peptic disorder is a pain in the abdomen typically non radiating, burning, andlocated at in epigastrium, Other include nausea, vomiting, dyspepsia, haemtemesis, and melena, etc. Uppergastrointestinal tract disorders are common in surgical practice. Helicobacter pylori is a common cause ofacid peptic disorders. Still in literature there is a controversy still exist to question about role of Helicobacterin causing acid peptic disorders. So This study was undertaken to evaluate the correlation of H. Pyloriinfection with acid peptic disorders. Method: This study was a prospective observational. The durationof this study was from September 2017 to September 2019. The numbers of patients were 150. After theestablishment of a clinical diagnosis of an acid peptic disorder, the patient was posted for endoscopy. H.pylori status was determined by the rapid urease test. The data collected included the presenting complaints,clinical signs, endoscopic findings, results of rapid urease test, and histopathological examination. Thepresence of H pylori infection was correlated with symptoms, and endoscopy findings. Results: In the presentstudy, 150 patients with upper gastrointestinal symptoms were studied It was found that the maximumnumber of subjects belonged to the age group 31-40 yrs. It was found that of subjects male 112 and female.It was found that maximum number of subjects had pain in epigastric region 120 cases i. e. 80% followedby symptoms nausea 75 cases ie. 50%. about endoscopic findings .70 patients were having gastritis,15 hada duodenal ulcer,9 patients had Duodenitis, the gastric ulcer was found in 08 patients, gastric malignancyin 02 patients and 46 patients had endoscopic normal mucosa. The highest positivity of RUT was seen inpatients of duodenal ulcers (86.66%), followed by gastritis (82.85%) and gastric ulcer (75%). Conclusions:Present study, we have found that there is an association of H. Pylori infection in an acid peptic disorder likeduodenal ulcer, gastric ulcer, and gastritis.
Increased Paediatric Screen Time During Pandemic: A Cause of Concern to Child Health Yogita Shrivas1, Sujata Shamkuwar2, Radha Andhare2, Ashish Varma3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.12754

Abstract

COVID-19 has put the globe in an unforeseen and unexpected situation. COVID-19 has affected everydaylife all over the world. Human population came face to face to this virus so gravely for the first time.During the initial days nearly all countries imposed lockdown to break the chain of viral spread. This createdsignificant knock-on effects on the daily life of citizens. With the updates on COVID-19, the guidelinesissued by medical authorities, categorized geriatric and paediatric age groups to be at high risk. In order toflatten the rising curve of exponential spread of the virus ban on gatherings resulted in enforced shut downof schools. Therefore children were bound to stay home. They were automatically exposed to the over useof electronic gadgets for recreation as well as education purpose .Hence, their screen time increased manyfold. This paper describes the impact of COVID-19 and use of electronic screen on children.
Indirect Impact of COVID-19 Lockdown on Society and Environment Radha Andhare1, Yogita Shrivas2, Shubhada Guru3, Abhishek Joshi4
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.12755

Abstract

In a fairly short time, the worldwide spread of COVID-19 has brought a dramatic reduction in industrialactivities, road traffic and tourism. During this time of crisis restrained human interaction with naturehas appeared as a blessing for nature and the environment. Reports from around the world indicate thatenvironmental conditions, including air quality and water quality in rivers, are improving after the COVID-19outbreak, and wildlife is blooming. India has always been a pollution hub with enormous populations. Butsince COVID-19 announced the lockdown, air quality has begun to improve and all other environmentalparameters such as water quality in rivers have begun to offer a positive sign of restoration
Assessment of age in female population by radiographic examination of Carpal bones Pawan A. Wankhade1, Rajesh B. Ramteke2, B.H. Tirpude3, Ninad Nagrale4, Shailesh Nagpure5
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.12756

Abstract

Introduction: Assessment of the age of an individual from the appearance and the fusion of the ossificationcenters is a well-accepted fact in Medical and Legal professions. In the age estimation of juvenile offenders,radiological examination of bones gives valid idea of age needed in courts.Objectives: Aim was to assess the age of the ossification of carpal bones at wrist joint in females. Theobjectives were to estimate the age specific difference in all subjects, also to study difference age ofossification in central part of India with other part of country and abroad.Method: After obtaining the ethical clearance the subjects below the age of 20 years residing in centralIndia were included in this study. As per inclusion criteria carpal bones forming wrist joint were examinedradiologically with standard accepted procedures and guidelines to assess the age.Result: The outcome of this study was very fruitful and knowledgeable as it revealed age specific differenceand remarkable difference in the age of ossification as compared to the foreign countries and other parts ofIndia.Conclusion: Radiological examination plays very vital role in age estimation in judicial cases. It can beconcluded that such studies should be conducted with good sample size and at regular intervals for academicas well as in judicial point of view.