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INDONESIA
Indian Journal of Forensic Medicine & Toxicology
Published by Official Organ of Indian Association of Medico-Legal Expert
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Public Health
Arjuna Subject : Kedokteran - Epidemilogi
Articles 5,497 Documents
 387   388   389   390   391 
The Possible Effect of Celastrol on Ameliorating Mitochondrial Dysfunction and Neuro-inflammation in Sodium Valproate Induced- Rat Model of Autism AmlAlaa El-Din El-Sayed Ahmed; Samia HussienAbou El-Seoud; Fleur Fathi Abdel Moneim; Rasha Osama El-Esawy
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 2 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i2.17920

Abstract

Autism spectrum disorder (ASD) is a neurodevelopmental disease with impairment in social interactions,language and repetitive stereotypical behaviors. Celastrol is a natural safe compound that has antiinflammatoryand as a neuroprotective effects. 48 male offspringswistar rats divided into 6 groups;normal control group, offsprings receive vehicle, autistic offsprings receive vehicle, autistic offspringsreceive risperidone, autistic offspringsreceive celastrol, autistic offspringsreceive both risperidone&celastrol. At the end of experiment behavioral tests were performed then neurochemical analysisand histopathological examination. The obtained data showed that celastrol improved social deficits,decreased repetitive/restricted behaviors in T-maze test, significant increase in SIRT-1, GSH levelwith significant decrease in DRP-1, IL-6, caspase-3 and MDA with amelioration of histopathologicalfindings in VPA-induced ASD in both cerebellum and hippocampus. These findings pave the way forusing celastrol as an adjuvant therapy during long-term clinical use of risperidone in ASD.
The Effectiveness of Facet Joint Local Corticosteroid Injection in Diagnosis and Treatment of Facet Joint Syndrome Amr Sabry AlBakry; Ahmed Saleh ElSayed; Hamada Mostafa AbdulAal; ElSaid Hamdy Zaki
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 2 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i2.17922

Abstract

Objectives: To evaluate outcomes of lumbar facet joint injection with local corticosteroid in treatmentof chronic low back pain according to Oswestry disability Index(ODI).Patients and Methods: Interventional prospective study on 23 patients attended the outpatient clinic ofOrthopedic Surgery in Cairo University Hospitalscomplaining of chronic low back pain not responsiveto medical treatment and physiotherapy from September 2018 to august 2019.Results: The mean age of the patients was 41.17 ± 9.74 years and 47.8% were males. Facet jointcorticosteroid injection resulted in significant reduction of pain severity of patients as it ranged 5:10(mean 7.3 ±1.5) pre-injection and improved to 0 :6 (mean 3.6 ± 1.7) 3-month post injection(Pvalue:0.001)while the ODI score ranged 26:80 (mean 47.4 ±15.7) pre-injection and improved to 4:46 (mean 28.8 ±10.4) three months post injection(Pvalue 0.001).Conclusion: intra-articular facet joint injection is crucial in the diagnosis and treatment of facet jointsyndrome.
The Management of Giant Cell Arteritis (GCA) Overlapping with Sjogren Syndrome : A Case Report Arina Mana Sikana; Awalia
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 2 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i2.17923

Abstract

Giant cell arteritis (GCA) is an autoimmune vasculitis involving large and medium arteries. GCA israrely associated with autoimmune diseases, such as Sjögren’s syndrome. Glucocorticoids (GC) arethe cornerstone of the treatment of GCA as they are very effective but are often given for 1 year toavoid relapses. Here we report a rare case of GCA overlapping with Sjögren’s syndrome along with themanagement.
Smart Materials- A Review Arpit Arora; Anushka Arora; Karthik Shetty
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 2 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i2.17926

Abstract

3rd Year Post Graduate Student, Department of Conservative Dentistry and Endodontics, Manipal College of Dental Sciences, Mangalore, Manipal Academy of Higher Education
Effect of Oxytocin Augmentation on Neonatal Bilirubin Levels : A Case Control Study Jitendra Shukla; Shubhra Buch; Piyusha Chandrayan
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 2 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i2.17928

Abstract

Introduction - Hyperbilirubinemia is a commonly encountered problem in both term as well as preterminfants and is a source of concern to neonatologists.Aim- to determine the relationship between the usage of oxytocin during labour and the developmentof neonatal hyperbilirubinemia.Methodology- a case controlled study was conducted. 50 patients were given intravenous oxytocinfor the augmentation of their labour and 50 patients delivered spontaneously without the usage ofoxytocin during their labour. The neonates born to both these categories of patients were studied fortheir bilirubin levels of day 2 of life.Results- hyperbilirubinemia developed in 34% of the neonates whose mothers were given oxytocin foraugmentation of labour and hyperbilirubinemia developed in only 14% of the neonates whose mothersdelivered spontaneously without the usage of oxytocin.Conclusion- A positive relationship between the usage of oxytocin during labour and development ofneonatal hyperbilirubinemia has been established.
Study of Working Hours of Indonesian Civil Servant Doctors in Relation to the Rule of Three Licenses for Practice and Labor Law Noviana Indarti; SherlyIntan; Sylvia Meylinda; Tagor Sibarani; Mokhamad Khoirul Huda
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 2 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i2.17932

Abstract

There are no specific rules about doctors’ working hours in Indonesia, it causes working hours ofIndonesian doctors to be excessive. Following the rules of the labor law that the maximum work of aworker is 40 hours a week. However, with the applicable 3 Licenses For Practice rules, the doctor’swork hours will be more than 40 hours a week. It was to examine whether the working hours ofIndonesian Civil Servant doctors are rational.Based on Law No. 13 of 2003 about Manpower article77 paragraph (2), the maximum working hours of a worker is 40 hours. In reality, with the 3 LicensesFor Practice rules, if it was calculated, the working hours of civil servant of doctors in Indonesia wasvery excessive. In other countries, there were already standard rules. Doctors work 40 hours a weekor a maximum of 80 hours a week. Therefore, it needed to be studied further, whether the 3 LicensesFor Practice policy had provided a solution or had actually aggravated the condition of a civil servantdoctor. The monoloyalty discourse of a doctor needed to be balanced with an increase in the services orincentives of a civil servant doctor.With the rule of three Licenses For Practice, the working hours ofcivil servant doctors in Indonesia became excessive.
Profile of Pneumocystis JiroveciiPneumoia in HIV/AIDS Patients in Dr. Soetomo General Hospital of East Java Province Pius Sebastian Ginting; Bramantono; RestiYudhawati Meliana; Musofa Rusli
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 2 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i2.17933

Abstract

Background: Human immunodeficiency virus (HIV)-infected patients if not treated will experienceacquired immunodeficiency syndrome (AIDS). People with AIDS will suffer opportunistic infection.One of the common opportunistic infections is Pneumocystis jirovecii pneumonia (PCP). PCP is aninfection caused by the fungus Pneumocystis jirovecii which infects patient’s lungs. The purpose of thisstudy is to analyze the profile of HIV/AIDS patients with PCP in Dr. Soetomo Hospital.Methods: This is a retrospective descriptive study based on medical records obtained from the inpatientward of Dr. Soetomo General Hospital Surabaya. A total 21 patients enrolled in this study who met theinclusion criteria. The data are retrospectively described by demographic characteristics, CD4 count,clinical symptoms, blood gas, and lungs radiographic features.Conclusion:Major findings of PCP in HIV/AIDS patients was in the group of age 25-49 years (85,7%),male (85,7%), high school graduate (71,4%), employed and unmarried (66,7%). The most commonclinical symptoms were dyspnea (100%), PaO2 ≥70 mmHg (61,97%), CD4 count <50 cells/μL (76,2%)and the most common radiographic features was bilateral interstitial infiltrates (95,2%).
Early Childhood Malnourishment and its Associated Factors - Uttarakhand Pratiti Haldar; Lekha Viswanath; Ashok Kumar Srivastava
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 2 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i2.17935

Abstract

Malnutrition, a word which seems to shake our roots and disturb our future. Today the underdevelopedand many developing countries are battling this threat in many ways. The reason behind malnutrition isthe determinants which make it prevail in our neighborhood and our country on the whole. Malnutritionpossess a very serious threat to the future of our country especially the children between (1 – 3) years ofage. This paper attempts to identify the existing prevalence of malnutrition in Uttarakhand, to explorethe predisposing factors contributing to it in under five children and compare the prevalence with theselected neighboring states. An in – depth survey of all the related literatures and published articles in theselected area was made. It has been reported in recent times about the hike in India’s hunger problemsand the number of reported cases of stunting and wasting has also rocketed though underweight hasslightly reduced. The only way to curb malnutrition is by; breaking the shackles of the determinants,thorough regular surveys and screenings, improved and adequate health care services, reaching out tothe needy and spreading awareness among the masses.
A Quasi-Experimental Study to Assess the Effectiveness of Guided Imagery Therapy on Infertility Related Stress and Quality of Life among Infertile Women Priyanka Christian; Sapna Bhavin Patel; Anjali Tiwari
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 2 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i2.17937

Abstract

Introduction and Background: According to WHO infertility is failure to achieve a pregnancyafter 12 months or more than or without use of any contraception method, it is a reproductive systemdisease.Infertility can cause increase level of stress and create negative thought. So this study isaimed to find out effectiveness of guided imagery technique on stress and quality of life of infertilewomen. Methodology: The research approach used was quantitative approach. Quasi experimental:nonequivalent control group, Pre-test post-test design was used. 66 infertile women were selected forboth the group was selected 33 subjects in each group. Pre assessment for stress level & quality oflife was done for both experimental and control group. The tool of data collection included a sociodemographicPerforma, Perceived stress scale (PSM- 10) and FertiQol scale assessment tool. Guidedimagery provided to experimental group. The intervention was given to infertile women is recorded15 minutes audio tract. Participants had listened the infertile specific GI recording once in a day for 7consecutive days. In control group, the GI therapy did not provided. Result: The data was analyzedby using descriptive and inferential statistics. The study result shows that effect of GI intervention onstress intensity and on QoL are effective and P value for stress was <0.001 and for QoL p value was<0.001. Conclusion: The study concluded that Guided imagery technique is effective in reducing stresslevel and improve quality of life.
Meta Study of the Relationship between Knowledge and Incentives with Posyandu Cadre Performance Arjan Arkasi; Syamsul Arifin; Ari Yunanto; Eko Suhartono; Fauzie Rahman
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 2 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i2.17939

Abstract

Background: Posyandu cadre performance refers to the role of cadres in posyandu activities as inthe Posyandu cadre handbook, explaining the role of posyandu cadres is divided into three stages,namely before posyandu opening days, posyandu opening days and after posyandu opening days. Manystudies report different results on the performance of health cadres related to knowledge and incentives.The purpose of this paper is to analyze the relationship between knowledge and incentives with theperformance of posyandu cadres.Method: The research method used is meta-analysis to assess how big the effect of the knowledge andincentive variables will be on the performance of posyandu cadres.Result: Based on the results of the study of research articles, the combined P-value of 0,000 on theknowledge variable, and the combined p-value of 0,039 on the incentive variable.Conclusion: There is a relationship between knowledge and incentive variables on the performance ofposyandu cadres.

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