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Enucleation of Scrotal Epidermoid Cyst: Case Report
Halim Perdana Kusuma;
Nugrohoaji Dharmawan
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 2 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd
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DOI: 10.37506/ijfmt.v16i2.17957
Background: Epidermoid cyst is one of the most common forms of blockage in the pilosebaceousgland. The surgical procedure for excision of the cyst aims to prevent recurrence, however, severalreports suggest that enucleation can be performed with certain considerations.Case:A 22 year old man who lives in Wonogiri, came to Dermatology and Venereology Outpatientclinicof Dr. Moewardi General Hospital Surakarta, with the chief complaint of a lump in the scrotum. Thelumps appeared since 3 years ago, the size of a pea seed and accompanied by itching. The resultsof the examination of the dermatological status of the scrotal region showed several nodules of theskin color, felt dense and rubbery without any signs of inflammation. Histopathology shows a basketwave type parakeratosis at the stratum corneum, while the epidermal layer shows cysts filled withkeratin and surrounded by squamous cells. Based on the results of the history, physical examinationand histopathology, the diagnosis of the patient was a scrotal epidermoid cyst, then we performed twoenucleation measures and found improvement.Conclusion: Epidermoid cyst is a form of benign epithelial cyst that can occur in the scrotal area. Themain treatment to prevent recurrences is surgery, where the enucleation technique can be performedwith several considerations such as small size of the cyst without signs of inflammation, preventingdystrophic calcification and capsule routine.
Role of Fine Needle Aspiration Cytology in Evaluation of Cervical Lymphadenopathy
Harsimrat Singh;
Abhay Kumar Singh;
Inderpreet Singh Oberoi
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 2 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd
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DOI: 10.37506/ijfmt.v16i2.17958
Introduction: Cervical lymphadenopathy is one of the commonest clinical presentations of patients ofhead and neck pathologies. Metastatic cervical lymphadenopathy is a common presentation in head andneck oncology. The aim of this study is to evaluate the effectiveness of FNAC as a primary investigationtool.Aims and Objectives: The aim of the study was to evaluate the effectiveness of FNAC in diagnosingcervical lymphadenopathy.Material and Methods: A study was conducted in the Department of Pathology and E.N.T.,SIMS, Hapur, U.P., India from January 2019 to February 2020 which included 52 patients withcervical lymphadenopathy presenting to outpatient clinics. FNAC was done in patients of cervicallymphadenopathy before surgery or incision/excision biopsy and the results of FNAC was correlatedwith histopathological evaluation.Results: In our study 88.47.% of sensitivity and specificity of 92.03% was found on FNAC of cervicallymph nodes.Conclusion: FNAC remains a safe, cost effective and appropriate first line investigation though theresults have to be confirmed with HPE for proper evaluation and management.
Effect of Tamsulosin on Biomarkers after Kidney Stones Lithotripsy
Iman A. Ismael
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 2 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd
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DOI: 10.37506/ijfmt.v16i2.17966
The disease of kidney stones is one of the urinary system’s oldest and most common issues. Children with kidney stones have also become more popular, In recent years. Kidney stones are also very painful, and in some people, they can continue to occur. Kidney stone attacks result in over 2 million visits to health care facilities . People tend to get stones in the middle of life. During midlife, family and work commitments are at their height, which makes kidney stones costly. The diagnosis, treatment and prevention of kidney stones and the time away from work due to stones cost approximately $5.3 billion a year. To understand the effect renal some biomarkers in patients with kidney stones, before and after Lithotripsy and to evaluate the effect of Tamsulosin on these biomarkers in patients. Forty patients and twenty healthy persons were participate in this case-control study, Bl.urea, level of ALP, Level of KIM1, and level of Na c were investigate in serum with kidney stones patients and control healthy persons. The results were shown significant elevation in the levels of KIM-1, and serum urea were decreased significantly (p value <0.05) while the levels of ALP and serum sodium show an improvement when compared to patients who were not used tamsulosin but it’s results were statistically not significant. the results were given an evidence for the crucial role of some biomarker in serum in patients with kidney stones, also the effects of using tamsulosin for 14 days in patients with kidney stones who underwent lithotripsy compared with those patients who were not used tamsulosin.
Stimulation of Growth and Development of Pandalungan Toddler in Indonesia
Lantin Sulistyorini;
EkaAfdi Septiyono;
NuningDwi Merina;
PeniPerdani Juliningrum;
Ira Rahmawati
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 2 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd
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DOI: 10.37506/ijfmt.v16i2.17967
Background: The delay in growth and development is still a serious problem for both developed and developing countries in the world. One of the factors that cause delays in growth and development in toddlers is the lack of early stimulation of toddler development.Solving the problem of child growth and development cannot be separated from the existence of cultural diversity.Method: The qualitative research methods through a phenomenological approachwas chosen as the approach because this study tried to explore parents’ behavior in fulfilling the growth and development stimulation of the Pandalungan ethnic group.The sampling technique in this study used purposive samplingParticipants in this study were 15 participants with in-depth interviews used a semi-structured interview. Results: The results of the research get three main themes, and each theme has a sub-theme. The theme of stimulation from the family (Interaction with family, Parent’s Education, Parent’s Economic and Technology).The theme stimulation from social (Interaction with neighbors and government regulation). The theme Stimulation from culture and value(Cultural factors and values in society and Religious factors).Conclusion: The role of the family is needed in stimulating the growth and development of children because it will affect the growth and development of children.Social influences and government policies affect parents in stimulating growth and development. Culture and values will affect the growth and development of children because children are raised in that environment, so that they must follow the rules in the social environment.
Social Status and Oral Hygiene with Quality of Life in Patients with Primary Hypertension
Masriadi;
Muhammad Fajrin Wijaya;
Maqh irah Amiruddin;
Tuti Alawiyah;
Nur Rahmayani
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 2 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd
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DOI: 10.37506/ijfmt.v16i2.17968
Background:The main problem in primary hypertension is that most people who have been diagnosed with primary hypertension do not know the etiology clearly.To find out the the relation between social status and oral hygiene with quality of life in primary hypertension. Methods:The type of research used was an observational in a cross-sectional study design.The study was conducted in February-May 2021. The number of sampling was 61 people. The sampling method uses purposive sampling technique. The results of data collection were tested by using the Path Analysis test.Results: Research conducted at Padongko Public Health Center in Barru Regency. Based on the results of the analysis of the path analysis of social status tests on primary hypertension, the results obtained p value 0.188> α 0.05, oral hygiene against primary hypertension results obtained p value0.914> α 0.05, this Ha obtained means that there is a the relation but not significant, while social status on quality of life results are obtained p value 0.837> α 0.05, oral hygiene against quality of life results obtained pvalue0.227> α 0.05, this Ha obtained means there is the relation but not significant, while the the relation of primary hypertension to quality of life has a significant the relation where the results of p value 0.012 <α 0.05.Conclusion: There is the relation between social status and oral hygiene with quality of life in patients with primary hypertension but does not appear significantly.
Diagnostic Problems in Leptospirosis Patients : A Case Report
Megawati;
Musofa Rusli
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 2 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd
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DOI: 10.37506/ijfmt.v16i2.17969
Leptospirosis is a zoonosis infection found in almost every part of the world but is mostly endemic in tropical and subtropical countries. In 2013 there were 640 new cases reported with 60 death cases (CFR 9.37%). An increase in new cases had caused an outbreak in Sampang, Madura due to a flood following a high rainfall. A male patient aged 45 years old with Leptospirosis. The diagnosis was made based on the epidemiology, clinical manifestations, and Microscopic Agglutination Test (MAT) examination data. In the early treatment, the examination of IgM and IgG Leptospira showed negative results a confirmation with MAT examination was done subsequently. Diagnosis using MAT also provides information about an outbreak in a region. Upon receiving antibiotic and symptomatic treatments and clinical recovery, the patient’s condition continued to improve.
Serum Levels of Interleukin-2 and Interleukin-6 among Helicobacter Pylori Positive Patients in Relation to Prognosis of Gastro-duodenal Disease
Methaq M. Neamah AL-Hilfi;
Khairallah A.S Mohammed;
Naael H. Ali;
Ali Dawood AL-Hilfi
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 2 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd
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DOI: 10.37506/ijfmt.v16i2.17970
Background: Helicobacter pylori is the most widespread pathogenic associated with gastro-duodenal Disease. Interleukin 2 and interleukin 6 are the main cytokines involved in host immune response to H.pylori infection. The aim of the present study are to assess the serum level of IL-6 and IL–2 in H.pylori infected patients and to study their association with gastric endoscopy findings. Methods: One hundred and seven suspected patients and 19 healthy were recruited. The confirmed positivity of H.pylori detection was based on a rapid urease test (R.U.T) and stool antigen test. Serum concentrations of IL-2 and IL-6 were measuring by ELISA. Results: Seventy-five (70%) patients were positive for H.pylori. Both interleukins were found at higher levels in patients than in healthy (p- value <0.05). Interestingly, the level of IL-2 was lower in patients infected with H.pylori (43.40 pg/ml) than those who were not infected (85.2 pg/ml), while the level of IL-6 was higher in patients infected with H.pylori (117 pg/ml) than those not infected (40 pg/ml), p-value <0.05. Furthermore, the increasing levels of both interleukins were correlated with disease progress.
Transnasal Esophagoscopy Procedure in Outpatient Clinic at Dr. Soetomo General Academic Hospital
Muhammad Qodri Anantomo;
Rizka Fathoni Perdana
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 2 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd
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DOI: 10.37506/ijfmt.v16i2.17971
Background: Transnasal esophagoscopy is a small caliber flexible esophagoscopy technique that has the same as diagnostic accuracy as conventional esophagoscopy. In addition, this technique is safer than any other techniques and has patient tolerance. Aims: This study aims to analyze and evaluate the transnasal esophagoscopy (TNE) procedure in patients. Method: retrospectively approach was used in this study by taking data from the activity register of the broncho-esophagology division of outpatient unit of ORL-HNS Dr. Soetomo General Academic Hospital. TNE report book and patient medical records were collected to have the data. The observation period was 2013 to 2017. Result: patients who met the inclusion and exclusion criteria was 99 patients, with a male to female ratio of 2.3: 1. Most endoscopic findings were normal esophagus (56.57%). Existing abnormal findings included esophageal stenosis (18.18%), esophageal mucosal lesions (14.14%), and esophageal tumors (11.11%). TNE examination complications were found to be 1%. Conclusion: Transnasal esophagoscopy is widely used in patients aged 51-60 years with dysphagia, reflux or globus as the most common indications. TNE is quite safe to do in an outpatient hospital setting.
Comparison of the Effect of Glycemic Control on the Incidence of Fetal Macrosomia and Large for Gestational Age in Gestational Diabetes Mellitus Patients; A Systematic Review
Natasha Tiara Bernadette;
Budi Prasetyo;
Sony Wibisono;
Bambang Purwanto
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 2 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd
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DOI: 10.37506/ijfmt.v16i2.17972
Background: Gestational diabetes mellitus (GDM) can be managed with blood glucose control management, which includes a healthy lifestyle, insulin therapy, and oral anti-diabetic drug (OAD) medications when needed. Sub-optimally or poorly managed GD Mmay lead to arisk of complications, one of which is an abnormal growth in the fetus. This study aimed to compare the effect of blood glucose control management on the incidence of fetal macrosomia and large for gestational age (LGA) births in patients with GDM. Methods: This systematic review study obtained data from formerly published studies from the Science Direct database. The article search method used the characteristics of PICO (Population, Intervention, Comparison, Outcome) and compiled using the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) method. Conclusion: The use of medical nutrition therapy (MNT) and exercise in the therapeutic regimen, as well as routine monitoring of glycemic levels are very important to control the patient’s glycemic level. The use of metformin can increase the success of therapy due to reduced levels of LGA and macrosomia in GDM patients
Antibacterial Activity of Antimicrobial Peptide Indolicidin against Multidrug-Resistant Klebseilla pneumoniae Isolated from Patients with Burns
Noor Ibrahim Zaidan;
Kais Kassim Ghaima;
Hayder Mazin Rasool Al-Haboobi
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 2 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd
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DOI: 10.37506/ijfmt.v16i2.17973
The emergence of multidrug resistant Klebsiella pneumoniae has become a significant problem worldwide and also being a major threat to patients with burns infections. The therapeutic action of antimicrobial peptides derived from humans or animals or synthetic peptides attracted attention as alternatives for antibiotics in order to treat the resistant strains especially with strains isolated from burn patients. The current study investigated the role of antimicrobial peptide Indolicidin as an antibacterial agent with multidrug K. pneumonia isolates from burns. The collection of study samples has taken place at the period between November 2020 and completed at end of March 2021, it has included 250 clinical specimens as burn swabs from inpatients with burn infections admitted in four hospitals in Baghdad. The results of selective media, biochemical tests, and Vitek2 system identified 40 isolates (16%) as K. pneumoniae from all collected bacterial cultures. The results of the antimicrobial susceptibility test by using the disc diffusion method for the isolates under study showed that K. pneumoniae clinical isolates were moderate resistant to the majority of the antibiotics tested. The majority of K. pneumoniae isolates were high resistant to Erythromycin (100%) and Ceftazidime (85%), also, it was obvious resistance to Ceftriaxone, Cefepime and Cefotaxime, while the lowest percentage of resistance was for Impenem (25%) and Meropenem (38%). The results of minimum inhibitory concentrations (MICs) of indolicidine against (10) K. pneumoniae isolates which multidrug resistant and formed the strong biofilm, revealed that range of concentrations of indolicidin was (0.7-100 µg/ml) and it was obvious that there is a significant effect of indolicdin on the growth of K. pneumoniae at very low concentrations. In this study, we believe that the development of these antimicrobial peptides may become a new generation of urgently needed antimicrobials that can overcome bacterial resistance mechanisms.