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INDONESIA
Indian Journal of Forensic Medicine & Toxicology
Published by Official Organ of Indian Association of Medico-Legal Expert
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Public Health
Arjuna Subject : Kedokteran - Epidemilogi
Articles 5,497 Documents
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Prevalence of Lung Cancer in Non Smoker Patients Attending Al-Diwaniyah Teaching Hospital Hassan Raji Jallab1 , Thimar Malik Khudhair2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.2954

Abstract

Background: Smoking is a well known risk factor that is implicated in a number of human malignant disorders. Aim of the study: To study the prevalence of lung cancer in a sample of Iraqi non smoker patients and the main risk factor implicated in such malignant tumor. Patients and Method: In this hospital based study, in order to explore the prevalence rate of bronchogenic carcinoma in non smoker patients ,it retrospectively collected data about those patients for the last four years, starting from January 2016 through June 2019. These information were retrieved from patients records that are already present in oncology and respiratory units in Al-Diwaniyah teaching hospital, Al-Diwaniyah province, Mid-Euphrates region of Iraq. The following variables were included in the questionnaire form: Age, gender, occupation, education level, residency, socioeconomic status, marital status history of smoking, history of second hand smoking, number of household smokers, type of smoking, history of alcoholism, history of chronic illness, the main presenting clinical features and clinical features of carcinoma and finding in examination as well as those obtained from investigations. Results: In the current study, the prevalence rate of all cases of lung cancer during the period of study was 61 out of 403 (15.1 %). the rate of lung cancer in none smokers, in the current study, was 39.3 %. Old age individuals were the main age group affected and there was female predilection. there was also no significant difference in the distribution of patients and control subjects according to residency, occupation, level of education marital status and socioeconomic status (P > 0.05). In the current study, the prevalence rate of passive smoking in patients was significantly higher than that in control subjects, 70.8 % versus 40 %. Moreover, the number of household smokers was significantly higher inpatients group than in control group. Conclusion: Lung cancer in non smokers appears to be significantly correlated with passive smoking in addition to increase incidence in old age and women
Aging Influence Mitochondrial Dysfunction and Oxidative Stress through Check Some Proinflammatory Cytokines Levels and Oxidant Status in Older Adults: an Observational Study Kaniaw R. Khafar1, Esmail S. Kakey2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.2956

Abstract

The experiment design is that of a cohort study within the setting of a medium private laboratory with participants being common people (healthy individuals of 20–99 years=108; mean age 55 years and 71.3% man) were classified into six age groups. Oxygen saturation (SpO2), pulse rate, systolic blood pressure (CSBP) and diastolic blood pressure were assessed. Blood sera (once) was obtained for proinflammatory cytokines levels (including c-reactive protein (CRP), insulin growth factor-1 (IGF-1), apolipoprotein E (apoE), interleukin 6 (IL-6), 8-hydroxy-2’–deoxyguanosine (8-OHdG) and tumor necrosis factor-? (TNF-?)) and oxidant status (including malondialdehyde (MDA), superoxide dismutase (SOD) and total antioxidant capacity (T-AOC) analysis. The mean calculated of the whole participants were equal for proinflammatory cytokines levels: CRP 3.24 mg/dL, IGF-1 54.03 ng/mL, apoE 488.29 mg/mL, IL-6 65.464 pg/mL, 8-OHdG 1.34 ng/mL and TNF-? 105.63 pg/mL; and oxidant statue: MDA 0.59 ng/mL, SOD 3.48 U/mL and T-AOC 1.21 mmol/L, receptively. Our findings highlighted that survey of mitochondrial dysfunction and oxidative stress through check some proinflammatory cytokines levels and oxidant status of aging in older adults can be applied to build a global frailty index as a tool to quantify aging in preclinical experiments.
Robust Bayesian Estimators For Survival Function Under Prior Data Conflict With Practical Application in the Health Side Entsar Arebe Al.Doori1, Ahmed Sadoun Mannaa1
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.2958

Abstract

The analysis of survival functions is concerned with knowing how long humans will survive, This means studying and analyzing the time from the beginning of the disease to the end point of death. For example, the survival function of patients with heart attacks was studied and analyzed at Al Manathira General Hospital. The Weibull distribution was used to match the real data. The scale parameter & survival function have been estimated for Weibull distribution with have two parameters, this distribution was used in two cases, prior data unconflict & prior data conflict. A regular Bayes method & robust Bayes were used for estimation. We used inverse gamma distribution as a prior where it is a conjugate prior for Weibull distribution. Two simulation experiments have been used; the first experiment used was prior data unconflict where the regular Bayes method is the best for estimating the scale & survival function by using the integrated mean square error (IMSE) as a criterion for comparing. The second experiment is in the case of prior data conflict. The results showed that the robust Bayes method is the best for estimation of the scale parameter & survival function by using (IMSE).
Phenotypic detection of AmpC ?-lactamase in Pseudomonas aerogenosa isolated from Burns and Wounds in Al-Rumetha Hospitals Abeer Mohammed Ali Al-garawyi
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.2960

Abstract

Ampicillin hydrolyzing class C ?-lactamase (AmpC) producing Pseudomonas aeruginosa has been recognized to be a serious opportunistic infection and due to the wide ability to create ?-lactamases made this bacteria resistance to many antibiotics.The results of the current study showed that 36(27.7%) isolates of P. aeruginosa from 130 isolates examined for cefoxitin susceptibility by disk diffusion method. Out of thirty six P. aeruginosa isolates , 29(80.6%) were cefoxitin resistant . The modified three dimension test and AmpC disck test were used confirm the production AmpC ?- lactamase in all cefoxitin resistant isolates , only 23(79.3%) isolates were phenotypically confirmed to produce AmpC beta-lactamase. The result of this study showed that 12/36 ( 33.3%) isolates were positive with blaAmpC gene by conventional PCR technique
Assessment Knowledge of Thalassemia Care Giver in Kirkuk City Idrees Hasan Mohammed
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.2963

Abstract

Thalassemia is an inherited blood disorder, which is described by diminished synthesis or lack of globin,this synthetic defect leads to the formation of fragile abnormal red blood cells (RBC), which can be easily hemolyzed, leading to chronic anemia Quantitative design descriptive study was used to assess Knowledge Thalassemia Care givers in Kirkuk City. A non–probability / Convenience sampling technique was applied in the present study, (30) Thalassemia Care givers were participate in the study sample (Azadi Teaching Hospital) in Kirkuk City. A questionnaire was designed and constructed by researchers to measure the variables underlying the present study. Data were obtained directly by the researchers through interview technique. Content validity of the instrument was determined through the of panels which involve (5) experts to investigate the clarity. The findings in general indicated that Majority of the sample In general has good Knowledge about Thalassemia it was recorded (74,8%) were answered “I Know.
Evaluation the Effect of Nano Yttrium Oxide Addition on the Mechanical Properties of Room Temperature-Vulcanized Maxillofacial Silicone Elastomers Yasir N. Al-Mohammad
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.2966

Abstract

Objective: This study aims to investigate the effects of yttrium oxide (Y2O3) nanopowder inclusion on the mechanical properties, including tear strength, tensile strength, elongation percentage, hardness, and surface roughness, of room temperature-vulcanized maxillofacial silicone elastomers. Materials and Method: Y2O3 nanoparticles (30–45 nm) were added to VST50F platinum silicone elastomers in two weight percentages (1 and 1.5 wt%) as tested by the pilot study that showed superior results. A total of 120 specimens were qualified and divided into the control group and experimental groups (1 and 1.5 wt% Y2O3). Each group was subdivided into four identical subgroups in accordance with intentionally performed tests (tear strength, tensile strength and elongation percentage, shore A hardness, and surface roughness). For each subgroup, 10 specimens were used for each test. Data were statistically analyzed with significance level considered at p < 0.05. Scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR) were also conducted. Results and Discussion: SEM showed that NPs were distributed well within the silicon matrix. FTIR spectra proved no chemical reaction occurred between the Y2O3 NPs and VST50F silicone. Tear strength and hardness values significantly increased in the experimental groups compared with the control group. Tensile strength and surface roughness values increased non significantly. Elongation percentage values decreased non significantly. Conclusion: Incorporating Y2O3 NPs into VST50F maxillofacial silicone improved the tear strength with slight increase in tensile strength. Hardness and surface roughness increased but within accepted clinical levels. Elongation percentage slightly decreased.
Immunohistochemical Correlates of Epidermal Growth Factor Receptor Mutations in Lung Adenocarcinoma in Iraq Patient Sabreen Saleem AbdAlkreem Alsaqi1, Merza Hamza Homady Almurshidi1, Rand Muhammed Abdul-Hussein Al-Hu
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.2968

Abstract

We aimed to investigate the Detection of epidermal growth factor receptor (EGFR)mutations in lung adenocarcinoma by Immunohistochemical and correlation with Clinicopathological features. We used Fifty tissue blocks embedded in paraffin wax were obtained from 50 patient (16 female and 34males) suffering from lung adenocarcacinoma, while controls were 30 samples from healthy, Histopathological examination Study by (H and E stain)and detection of Mutation in EGFR(exon19) by RFLP-PCR, detection of protein expression EGFR by immunohistochemical method Our results have, confirmed the mean age of patients group was 51.84 +/-15.70 years and the median was 54, performed study the non correlation between stage of disease and age of patients. site of tumor was right sided of lung tumor, accounting for 58 % .Distribution of patients according to grade of tumor was, The results of this study showed non-significant correlation between age and grade, results of this study showed significant difference in EGFR Positive between patients and control healthy in Imunohistochemical, had found as not significant with age ,gender, sit of tumor, grade, stage, in Immunohistochemical method of EGFR Expression. while Gene EGFR deletion of exon 19were analyzed using mutant-enriched polymerase chain reaction (PCR) was not detected in all patients and control
Depression in Relation to Serum Ferritin a Cross-sectional Study at Najaf Governorate Ashwan Abdulzahra Hashim
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.2970

Abstract

depression is a common psychiatric disorder that leads to disability and increases morbidity and mortality, and iron deficiency is a common nutritional disorder in general population that lead to change in brain function and affecting the quality of life. Methodology; a cross-sectional study that was conducted at Iraq Al-Najaf governorate, patient with depression was (51), and control group was (95), both were assessed by Beck depressive inventory Arabic version for the scoring of depressive symptoms, for both group serum ferritin was evaluated from fasting blood sample. Result; The age of participants (mean=36.25 years), the male was (55) while the female (91), of them (88) were married, there is significant differences between groups in age group (36-45) years and female gender while not to another variable. serum ferritin was significantly deferent with P-value (0.001). Conclusion; there is a strong relationship between the level of serum ferritin and depression with inverse correlation.
Histological Evaluation the effectiveness of Aloe Vera oral gel Application on Gingiva Subjected to Dental Light –emitting Diodes Noor Abdulkareem Razouki1, Rawaa Abdul-Jabbar Mahmood1 , Hadeel Ali Mahdi 2, Mustafa Gheni Taher3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.2972

Abstract

Background: Aloe Vera (AV) is a medical plant used in dentistry with multiple uses proved as antiseptic, antifungal, antiviral and anti-inflammatory and very good in building the immune system with a natural compound that has no side effect, for that reason we use it as protective layer from the heat that generated from LED light cure during the filling or cementation procedure or others. Materials and method: Thirty-five male New Zealand rabbits of weight 1.5 –2kg were used in this study; they were divided into three groups. First group (5 rabbits) the gingiva of upper incisors is not exposed to dental LED light cure (control group), Second group (15 rabbits) which the cervical gingiva of upper incisors which is separated from light source by double transparent celluloid strips, cervical gingiva is exposed to LED curing light 6 seconds three times with 20 seconds interval. Third group (15 rabbits) same as 2nd group but gingiva covered by Aloe Vera oral gel. Animals’ scarifications were done at (0 day) immediately after exposure to curing light ,3 days,7 days healing intervals. Routine processing and sectioning technique was performed for histological evaluation. Results: Histological findings indicated variation in epithelial thickness, irregularity in basal cells layer and number of blood vessels of 2nd & 3rd experimental groups from 1st control group. The highest mean values of all measured Histomorphometrical parameters were observed in 2nd group 3 days after dental LED light cure exposure. Conclusion: Aloe Vera oral gel may be used on gingiva as a protective layer to decrease side effects of LED light cure on gingiva.
A Concordance Study between Polymerase Chain Reaction Assay and Conventional Culture-based Methods for Detection of Fusobacterium necrophorum Muhammed Asaad Saleh 1, Haider Ali Muhammed2 and Adil Ateyah Alnasrawi2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.2975

Abstract

Foot rot duo to Fusobacterium necrophorum is an important clinical economic disease in ovine, in order to inform identification and antibiotics selection, Conventional culture-based method and Polymerase chain reaction assays had been proposed to provide a good inter-rater reliability between these techniques, this study was aimed to differentiate the accuracy of conventional culture-based method and PCR technique for identification of Fusobacterium necrophorum in an ovine foot rot. Method: The current study was conducted on three farms of Kerbala governorate (AL-husseinyia, Al-Hurr and Ain Al-tmor cities) during the period from October 2017 to April 2018, pathological swab samples of the interdigital region of affected (n= 40) sheep and (n=40) goat were enrolled in this study, after the collection of swabs, the samples were divided into two partitions, each swab of the first partition was immediately collected into lighten tube containing 5 mL of thioglycollate broth enriched with 0.5% ground sheep and was transmitted to the laboratory for conventional culture-based method and the another partition of swabs was sealed with other cooled tubes containing 5 mL of thioglycollate broth enriched with 0.5% ground sheep for the laboratory of molecular investigations. Results: Fusobacterium necrophorum was identified in the pathological samples by the two following depended assays: and (46) swabs were positive by conventional culture-based method and (44) swabs were positive with PCR assay, Cohen’s kappa coefficient revealed P value for conventional culture-based methods vs. PCR assay of 0.056 and the current study was demonstrated a highly identification rates of Fusobacterium necrophorum in conventional culture-based methods rather than PCR assay. Conclusions: Current study documented conventional culture-based method and PCR assays were facilitate the identification of Fusobacterium necrophorum in case of presumed ovine foot rot, it also concluded that molecular assays should be depended in confirmatory detection of F. necrophorum in affected animals.

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