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<![CDATA[Effectiveness of Additional Intranasal Phototherapy through Decrease Score of Nose Symptom and Eosinophil Mucosa on Persistent Allergic Rhinitis ]]>
<![CDATA[Hamna Fitriah1, Roestiniadi Djoko Soemantri1]]>
<![CDATA[ Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology ]]>
Publisher : <![CDATA[Institute of Medico-legal Publications Pvt Ltd ]]>
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DOI: 10.37506/ijfmt.v14i2.3366
<![CDATA[Background: Allergic rhinitis (AR) is a common atopic disease but the available treatment has limited used and success rate. It has been suggested that intranasal phototherapy represents an alternative choice in the treatment of AR. Objective: This study aimed to analyze the effect of additional intranasal phototherapy to loratadine therapy compared with single loratadine therapy in order to decrease total nasal symptoms score (TNSS) and nasal mucosa eosinophil count in persistent AR patients. Method: Fifty-four persistent AR patients were divided into two treatment groups: group A and B treated with 10 mg loratadine once a day with additional intranasal phototherapy at 660 nm. 4.4 minutes 3 times a day for group B. Evaluation was based on TNSS and nasal mucosa eosinophil countpre and post 14 days of treatment. Result: The study conducted from July to August 2014 demonstrated significant average of TNSS decrease on group B compared to group A (p = 0.002). Also significant average of eosinophil mucosa nasal count decrease on group B compared to group A (p = 0.049). Both group A and B showed the smallest score of TNSS pre-therapy was 4 vs 6, however the highest score was 6 vs 12. Group A and B showed the smallest score of TNSS post-therapy was 0 vs 0, however the highest score was 8 vs 7. Conclusion: Additional intranasal phototherapy to loratadine therapy showed more effective compared with single loratadine therapy in order to decrease TNSS and nasal mucosa eosinophil count in persistent AR patients]]>
<![CDATA[Hydration Status and Degree of Clinical Severity Patients with Thrombotic Infarction Stroke ]]>
<![CDATA[Agung Nugroho1, Hendro Susilo1]]>
<![CDATA[ Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology ]]>
Publisher : <![CDATA[Institute of Medico-legal Publications Pvt Ltd ]]>
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DOI: 10.37506/ijfmt.v14i2.3367
<![CDATA[Background: Dehydration is common in acute ischemic stroke patients and associated with a poor increase in clinical outcomes. It is caused of the increase of hematocrit related to the infarct volume which is wider to the cerebra infarct patients. It is also related to the repeatedly emboli stroke and thromboembolic vena after the occurrence of the acute stroke. Objectives: To analyze the correlation between hydration status and clinical severity in patients with acute thrombotic stroke. Methods: This study was conducted by using control design consecutive admission sampling technique. Serum BUN and creatinine measurements were performed when patients were administered to the hospital. Dehydration was defined if the ratio of BUN/serum creatinine was >15. Patients were divided into dehydration and non-dehydrated groups. The degree of clinical severity was measured by using the National Institute of Health Stroke Scale (NIHSS) at 7 days of onset of stroke. Data were analyzed using chi square, fisher, t dependent test, and mann whitney (p <0.05). Result: There were 19.23% stroke patients with dehydration were in the case group and the control group were 9.62%. There was no significant correlation between hydration status and clinical severity in acute thrombotic stroke patients (p = 0.126; OR = 2.625). Conclusion: There was no correlation between hydration status and clinical severity in acute thrombotic stroke.]]>
<![CDATA[Prevalence of Benign Vocal Cord Disorder at Dr. Soetomo General Hospital Surabaya Indonesia in June 2015-June 2016 ]]>
<![CDATA[Lucia Miranti Hardianingwati1 , Diar Mia Ardani1]]>
<![CDATA[ Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology ]]>
Publisher : <![CDATA[Institute of Medico-legal Publications Pvt Ltd ]]>
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DOI: 10.37506/ijfmt.v14i2.3368
<![CDATA[Benign vocal cord disorder is a common case but its prevalence is difficult to determine. Reporting on the number of benign vocal cord disorder events is important for data management to arrange the effective management. Objective this research to determine the prevalence of benign vocal cord disorders, i.e. nodules, cysts, and vocal cord polyps. Method is a retrospective descriptive study conducted using medical record data of outpatient unit of Otolaryngology-HN division of larynx-pharynx Dr. Soetomo General Hospital Surabaya in the period of June 2015 to July 2016. Result benign vocal cord disorders consisted of 65.00% of subjects with nodules, 15.00% of subjects with polyps, and 20.00% of subjects with cysts. The ratio of male and female was 1: 1. The most age was 20-59 years old with 60.00%. The largest occupational group is professional voice user with 60.00%. The location of benign vocal cord disorders was in 1/3 of the bilateral anterior as much as 85.00%. The most frequently used therapy is non-operative with 65.00%. The conclusion benign vocal cords disorder with the types of vodal, polyps, and vocal cord cyst occurred in 4.21% of all patients with dysphonic complaints. Vocal cord nodules had the highest incidence among other types of cord vocal diseases with 2.73% while the highest prevalence was shown by vocal cord nodules with 4.42%.]]>
<![CDATA[Utilization of Deconcentration Health Funds in Planning, Budgeting, and Implementation in Indonesia ]]>
<![CDATA[Gurendro Putro1, Ristrini1, Tumaji1]]>
<![CDATA[ Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology ]]>
Publisher : <![CDATA[Institute of Medico-legal Publications Pvt Ltd ]]>
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DOI: 10.37506/ijfmt.v14i2.3369
<![CDATA[Background: Deconcentration funds are funds that given to regions in achieving the target echelon 1 indicator of the main units in the ministry of health with program performance indicators, then translated into echelon 2 targets with the achievement of activity performance indicators. This deconcentration fund is one for health financing in achieving the National Medium-Term Development Plan (RPJMN) in the health sector. Aim: to examine the allocation of deconcentrated funds in planning, implement, monitoring and evaluating. Method: the secondary data document was analyzed for the allocation of deconcentrated funds, from the center in each division of the program. This research was conducted for 4 months from September to December 2018. Result: the highest deconcentration funds from 2016 to 2017 were highest in the North Sulawesi provincial health department of 75.68% and 98.64%, while the lowest in the North Kalimantan provincial department was 39.25% and 68.03%. Whereas for 2018 the highest realiation was in the Southeast Sulawesi provincial health department at 97.36% and the lowest in the Aceh provincial health department was 72.86%. Conclusion: the deconcentration fund planning it is done top down and a menu of programs or activities has been determined. The amount of fund allocation has also been determined by the center, the regions only make and implement what has been made by the center. Activities in the area need to be monitored and evaluated both in substance and financial programs]]>
<![CDATA[The Influence of Slow Stroke Back Massage, Cold-compress and Warm-compress to the Level of Prostaglandin F2? (PGF2?) in Primary Dysmenorrhea ]]>
<![CDATA[Mukhoirotin1, Kurniawati1, Diah Ayu Fatmawati1]]>
<![CDATA[ Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology ]]>
Publisher : <![CDATA[Institute of Medico-legal Publications Pvt Ltd ]]>
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DOI: 10.37506/ijfmt.v14i2.3370
<![CDATA[The cause of primary dysmenorrhea is excessive release of the hormone prostaglandin F2-alpha (PGF2?). The aim of this study was to assess the influence of SBBM, cold-compresses and warm-compresses toward the level of PGF2? in primary dysmenorrhea, using Post Test Only with Control Group Design and PretestPostest Control Group Design. The subjects were 76 female-student, selected by purposive sampling. NRS used to measure the pain level and ELISA used to measure PGF2? levels. The data were analyzed by using Paired Sample T-Test, One-Way Anova and Kruskal-Wallis test. SSBM, cold-compresses and warmcompresses are effective to decreasing of pain level and PGF2? levels in primary dysmenorrhoea.]]>
<![CDATA[The Effect of Dexterity and Perturbation Exercise on Knee Osteoarthritis through Functional Balance and Power Improvement of Quadriceps and Hamstring ]]>
<![CDATA[Rini Lestari Ansanay1, Damayanti Tinduh1]]>
<![CDATA[ Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology ]]>
Publisher : <![CDATA[Institute of Medico-legal Publications Pvt Ltd ]]>
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DOI: 10.37506/ijfmt.v14i2.3372
<![CDATA[Backgrounds and Objective: Osteoarthritis (OA) is a set of joint disorders caused by different factors but has the same pathological changes. OA of the knee joint occurs mainly due to the tibiofemoral and patelofemoral joints as a continuous body weight support throughout human life both static and dynamic, thus gradually causing changes in the structure of the knee joint tissue. This study aimed to know the function and strengthening of muscle strength of quadriceps and hamstring in patient with knee osteoarthritis. Method: Twenty-two patients with knee OA (average age of 51.7 years; range 40 to 65 years) were randomly grouped into intervention group (agility and perturbation exercises plus strengthening exercise of quadriceps and hamstring muscles) and the control group (strengthening exercise of quadriceps and hamstring muscles). Both group participated in a four-week exercise. Balance function, quadriceps and hamstring muscles strength (BBS, TUG, EN-Tree 1 RM) were assessed before and after intervention. Result: The intervention and control group improved 1 RM quadriceps muscle (p = 0.0001) and 1 RM hamstring muscle (p = 0.0001) but there was no statistically significant difference between groups, score of BBS in intervention group improved significantly (p = 0.0001) and statistically increased significant between groups (p = 0.0001), score of TUG in intervention group improved significantly (p = 0.002) but there was no statistically significant difference between groups (p = 0.324). Conclusion: Supplementation of agility and perturbation exercises on strengthening exercise of quadriceps and hamstring to balance function provided additional benefit with respect to the BBS score after four-week intervention of patients with knee osteoarthritis.]]>
<![CDATA[Biocompatibility Test of Decellularized Cartilage Bovine Scaffold in Vitro and In Vivo ]]>
<![CDATA[Achmad Fachrizal1, Dwikora Novembri Utomo1]]>
<![CDATA[ Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology ]]>
Publisher : <![CDATA[Institute of Medico-legal Publications Pvt Ltd ]]>
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DOI: 10.37506/ijfmt.v14i2.3373
<![CDATA[Background: Incidence of cartilage defects was reported at 65.00% of the routine arthroscopy procedures. Dr.Soetomo Teaching Hospital Network Bank developed a cartilage scaffold from bovine that has been deselularized decellularized cartilage bovine scaffold (DCBS). It takes a study of biocompatibility test to prove that DCBS is not cytotoxic to cells and not generate a host response. Objective: To analyze the biocompatibility of decellularized cartilage bovine scaffold (DCBS) in vivo and in vitro. Methods and Materials: The subjects were experimental rats and experimental with in vitro and in vivo trials. The subjects were treated by toxicity test with MTT assay, irritation test using Draize Scale, acute/ pyogenic systemic toxicity test by observing changes in body weight and temperature, and implantation test by observing fibrous capsule formation and Immunoglobulin G. Data was analyzed by using Kolmogorovsmirnov, Independent T-test, Mutivariate Analysis of Variance (MANOVA), and Mann Whitney. Result: The percentage of viable DCBS (81.78%) and CBS (92.45%) was ?70% of the control; thus, it is non-toxic to the cell. Draize scale in each group was in grade 0. Changes in body weight (p = 0.981) and temperature (p >0.05) had no significant association between groups. There was a significant difference mean of the fibrous capsule (p = 0.000) thickness and no significant difference in the mean number of Immunoglobulin G which was formed at week 1 (p = 0.87) and week 4 (p = 0.63) after implantation between CCBS and DCBS. Conclusion: The biocompatibility test shows that DCBS is compatible as a biomaterial.]]>
<![CDATA[Predictors of Hospital Utilization Among Papuans in Indonesia ]]>
<![CDATA[Agung Dwi Laksono1, Ratna Dwi Wulandari2]]>
<![CDATA[ Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology ]]>
Publisher : <![CDATA[Institute of Medico-legal Publications Pvt Ltd ]]>
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DOI: 10.37506/ijfmt.v14i2.3374
<![CDATA[Hospitals were advanced referral health facilities or referrals for basic health services, it was very important for policymakers to know the factors that it was able to predict hospital use. The research objective was to determine the predictors of hospital use among Papuans in Indonesia. Data source from raw data of the 2013 Indonesia Basic Health Survey. Indonesia Basic Health Survey was a cross-sectional survey. The multistage cluster random sampling method was used to get 30,620 Papuan respondents. Multinomial Logistic Regression Test is used to determine the predictors of hospital utilization. There were 8 predictors of hospital utilization in outpatients used consisting of age, urban-rural area, gender, education level, socioeconomic status, insurance ownership, travel time and transportation costs, there were 5 predictor variables in hospital utilization in patients hospitalization consisting of gender, type of work, socio-economic status, travel time and transportation costs, and there were 2 predictors in hospital utilization in outpatient and inpatient care at the same time consisting of the cost of time travel and transportation to the hospital. Overall there were 9 predictor variables of hospital utilization in all categories (outpatient and inpatient).]]>
<![CDATA[Hydration Status and Degree of Clinical Severity Patients with THRoMBotic Infarction Stroke ]]>
<![CDATA[Agung Nugroho1, Hendro Susilo1]]>
<![CDATA[ Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology ]]>
Publisher : <![CDATA[Institute of Medico-legal Publications Pvt Ltd ]]>
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DOI: 10.37506/ijfmt.v14i2.3375
<![CDATA[Background: Dehydration is common in acute ischemic stroke patients and associated with a poor increase in clinical outcomes. It is caused of the increase of hematocrit related to the infarct volume which is wider to the cerebra infarct patients. It is also related to the repeatedly emboli stroke and thromboembolic vena after the occurrence of the acute stroke. Objectives: To analyze the correlation between hydration status and clinical severity in patients with acute thrombotic stroke. Methods: This study was conducted by using control design consecutive admission sampling technique. Serum BUN and creatinine measurements were performed when patients were administered to the hospital. Dehydration was defined if the ratio of BUN/serum creatinine was >15. Patients were divided into dehydration and non-dehydrated groups. The degree of clinical severity was measured by using the National Institute of Health Stroke Scale (NIHSS) at 7 days of onset of stroke. Data were analyzed using chi square, fisher, t dependent test, and mann whitney (p <0.05). Result: There were 19.23% stroke patients with dehydration were in the case group and the control group were 9.62%. There was no significant correlation between hydration status and clinical severity in acute thrombotic stroke patients (p = 0.126; OR = 2.625). Conclusion: There was no correlation between hydration status and clinical severity in acute thrombotic stroke.]]>
<![CDATA[The Effect of Allogenic Bone Marrow Mesenchymal Stem Cell - Platelet Rich Plasma (Bmscs - Prp) Intra-Articular Injection Effect on the Regeneration of Full-Thickness Joint Cartilage Defect on Rabbit ]]>
<![CDATA[Ahmad Taufik.S1, Dwikora Novembri Utomo2, Hari Basuki Notobroto3]]>
<![CDATA[ Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology ]]>
Publisher : <![CDATA[Institute of Medico-legal Publications Pvt Ltd ]]>
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DOI: 10.37506/ijfmt.v14i2.3376
<![CDATA[Introduction: Full thickness cartilage defects are still a problem until present since the handling has not give any satisfactory results. Current handling is performed through cartilage enginering using mesenchymal stem cells alone and or in combination with growth factor. The purpose of this study was to investigate the effect of injection of intra-articular injection of Allogenic bone marrow mesenchymal stem cell - Platelet rich plasma (BMSCs-PRP) on regeneration of full thickness cartilage defect in rabbits. Method: The design of this study is a post-test only control group design using 36 New Zealand white rabbits divided into three groups treated with PRP, BMSCs and BMSCs-PRP. Results are evaluated after 10 weeks. Results: In the evaluation, macroscopic images showed the best healing in the BMSCs-PRP group. Histopathologic examination showed that in the MSCs-PRP group there was a significant increase in the amount of chondrocytes (p = 0.000), cartilage area (p = 0.000), as well as the number of Agecoprogenitor expec- tion cells (p = 0.000) and type 2 collagen (p = 0.000). Conclusions: Intra-articular injections Allogenic bone marrow mesenchymal stem cell (BMSCs-PRP) is able to regenerate and cure full-thickness joint cartilage defects through differentiation of MSCs into condroblasts.]]>
