cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Masriadi
Contact Email
arimasriadi@gmail.com
Phone
-
Journal Mail Official
-
Editorial Address
-
Location
Unknown,
Unknown
INDONESIA
Indian Journal of Forensic Medicine & Toxicology
Published by Official Organ of Indian Association of Medico-Legal Expert
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Public Health
Arjuna Subject : Kedokteran - Epidemilogi
Articles 5,497 Documents
 64   65   66   67   68 
Health Wisdom in the Traditional Healing of the Panaragan Java Subethnicity: The Case Study of Warok Ponorogo Alip Sugianto1, Wakit Abdullah2, Sumarlam3, Sahid Teguh Widodo4
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3377

Abstract

The Panaragan Java Subethnicity has a customary leader called warok. This leader is known for his ability to possess supranatural powers which may heal diseases. This traditional skill is obtained from the ancestors. It uses natural materials complete with the mantras. The aim of this research is to know the local wisdom in the field of health, especially in the art of Reyog from Ponorogo. This research uses a descriptive-qualitative design. The data is obtained through the technique of observation and interview. The results show that there are three types of health wisdom in the Panaragan subethnicity which are the wisdoms of health profession, medicine, and healing.
Correlation between Coenzyme Q10 Level Long-Term Steroid Inhalation in Patients with Bronchial Asthma Deny Perdana Putra1, Arief Bakhtiar2, Muhammad Amin2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3378

Abstract

Background: The main therapy of asthma is inhaled steroids and is often used for long periods of time. Coenzyme Q10 is a potent antioxidant produced largely by mitochondria. Treatment of long-term oral steroids can cause mitochondrial damage which lowers the level of coenzyme Q10. Objective: To analyze the relationship between coenzyme Q10 levels and long-term steroid inhalation in asthma patients. Method: The study was conducted at Asthma Unit/COPD of Dr. Soetomo General Hospital Surabaya Indoensia, Pulmonology Unit of. Dr. M. Soewandhie General Hospital Surabaya Indonesia, and Pulmonology Unit of Universitas Airlangga Hospital Surabaya Indonesia. We measured coenzyme Q10 levels and the duration of inhaled steroid use in the subjects. The data were processed using computer statistics program. The correlation between coenzyme Q10 level and long-term steroid inhalation was analyzed using Pearson correlation test (p <0.05). Result: Coenzyme Q10 levels in all samples were normal and increasing. There was no low coenzyme Q10 level found in all samples. The result of Pearson’s correlation test between coenzyme Q10 level with longterm steroid inhalation showed r = -0.037; p = 0.848 (p> 0.05). Conclusion: There was no correlation between coenzyme Q10 level and long-term steroid inhalation found in this study.
Association between Fear of Falling, Balance and Functional Mobility in the Elderly
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3379

Abstract

Background: Falling is the main problem that causes fear of falling in the elderly. Impaired balance is an important factor that causes falling. Falls Efficacy Scale-International (FES-I) is a tool to measure fear of falling, while balance condition can be measured using Biodex Balance System-SD (BBS-SD). Moreover, Timed up and Go Test (TUG) is a tool to measure functional mobility. The research aimed to determine correlation between fear of falling, balance and functional mobility in the elderly. Methods: The research was conducted in 39 elderly subjects at Outpatient Medical Rehabilitation Clinic of Dr. Soetomo General Hospital, Surabaya, Indonesia, who were measured using FES-I, BBS-SD and TUG. Results: The FES-I and BBS-SD probability values showed no correlation between fear of falling and balance, with p=0.064 (p>0.05). Moreover, the FES-I and TUG probability values also showed no correlation between fear of falling and functional mobility, with p=0.251 (p>0.05). Conclusion: There was no correlation between fear of falling, balance and functional mobility in the elderly at Outpatient Medical Rehabilitation Clinic of Dr. Seotomo General Hospital, Surabaya, Indonesia.
Relation between the Increase of Alpha Fetoprotein Serum Level and the Size of Hepatocellular Carcinoma in Multi Slice Computed Tomography Examination Ika Putri Maharani1, Nifa Koesmarsono1, Budi Laraswati1
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3380

Abstract

Background: Hepatocellular carcinoma can be diagnosed based on the result of Multi Slice Computed Tomography (MSCT) imaging only without histology result confirmation Objective: The aim of the study is to find out the relation between the increase of alpha fetoprotein serum level and the size of hepatocellular carcinoma in MSCT examination in Dr. Soetomo Teaching Hospital. Methodology: This is a retrospective, observational analytic study which uses secondary data. There were 50 samples with hepatocellular carcinoma. The data were collected from the medical records of MSCT subjects and AFP (Alpha-fetoprotein) serum level result. All recorded and analyzed statistically. Results: Of all the 50 samples, 41 are male (82%) and 9 are female (18%). The ages of the samples ranged from 19 to 76 years old with the majority of 51-60 years old in 15 patients (30%). Most distribution of AFP serum level was >400 ng/ml with 29 patients (58%) and tumor size of >5 cm with 49 patients (98%). The analysis using Spearman correlation test shows the correlation value p = 0.418 (p >0.05). Conclusion: There was no relation is found between the increase of alfa fetoprotein serum level and the size of hepatocellular carcinoma in MSCT examination.
Study of Gastroesophageal Reflex Disease in Adult Type II Diabetes Mellitus patients with Upper Gastrointestinal Symptoms Maysam Riyadh Mohammed Hussein Alaasam1, Sadiq Jabar Almohana2, Hayder Nadhum Muhsen3, Jalal Jasim A
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3381

Abstract

Gastrointestinal symptoms are relatively common in clinical practice in patients with type II diabetes mellitus. type II DM has been described as possible risk factor for the development of gastroesophageal reflux disease, in this study we aim to detect the prevalence of GRED in symptomatic patients with type II DM , also to see the accuracy of reflex disease questionnaire ( RDQ) in the diagnosis of GERD in patients with type II DM in relation to the esophagogastroduodenoscopy finding and to study the relation of autonomic neuropathy to the prevalence and stages of GERD in diabetic patients . Methods: A ninety patients with upper gastrointestinal symptoms was divided in to tow groups according to whether had type II DM or not and then each group involved in a two stage process (a ) – a RDQ , ( b ) – OGD. And patients in the DM group underwent another step to detect diabetic neuropathy by a bed side clinical test . Results: The prevalence of esophagitis in this study was higher in the DM group. RDQ had a statistical significance in detecting esophagitis in the DM group. There is no relation of autonomic neuropathy to the prevalence of GERD in diabetic patients . . Conclusion : The prevalence of GERD was high in patients with type II DM , RDQ is a sensitive tool for the diagnosis of GERD in diabetic pateints , Autonomic neuropathy did not increase prevalence of esophagitis in diabetic patients .
Association between Dose and Duration of Cisplatin Exposure with Sitotoksisity Effect on Nasopharyngeal Carcinoma Stem Cell Widodo Ario Kentjono1, Lakshmi Kusuma Wardhani1, Achmad C Romdhoni1
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3382

Abstract

Background: Nasopharyngeal carcinoma (NPC) is ranked 6th of malignant tumors in Indonesia, while cisplatin is an effective chemotherapy therapy but the side effects and resistance problems are two major constraints limiting its application. Objective: To analyze the correlation of dose and duration of cisplatin exposure with cytotoxic effects on nasopharyngeal carcinoma stem cells Methods: A true experimental laboratory in vitro with the factorial design was used in this study. The biopsy NPC tissue was cultured and processed to obtain NPC stem cells to be treated with cisplatin exposure at different doses (0.05, 0.1, 0.2, 0.4, 0.8, 1 and 2 ?g) and different durations (24 and 48 hours). The number of dead cells after exposure will be calculated using a hemocytometer after 24, 48, and 72 hours of NPC stem cells free of cisplatin. Results: Death stem cell density of NPC was mostly obtained at the exposure of 2 ?g/ml cisplatin dose after 24 hours observation was 81.37%, while the smallest death cell density a dose of 0.05 ?g/ml after a 72-hour observation was 21.3%. Statistical analysis with multiple regression correlation tests between the density of death cell and cisplatin dose was obtained the coefficient correlation 0,827 and value p = 0,000. The analysis of the correlation between cisplatin exposure duration and death cell was also significant with the correlation coefficient -0.357 and the value p = 0.001. The cutoff point that correlated the dose and death stem cell of NPC by 50% in both 24 and 48 hours of exposure was 1 ?g (EC50). Conclusion: There was a correlation between the increased dose of cisplatin with the cytotoxicity effects on NPC stem cell.
Optimization of Streptokinase Mutant Protein Purification Method Using Affinity Chromatography Technique Nastaran Rahimi1 , Mohammad AlinezhadChamazketi2, Amir Yaghoubi Nezhad3, Forough Talaeizadeh4
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3383

Abstract

Protein purification has always been one of the most critical and challenging stages of drug-protein production. Streptokinase as the most common, and currently, the most cost-effective fibrinolytic drug is no exception. In this study, the mutated streptokinase producing clone (SK263cyc) to which the histidine tag was added was grown in TY2x medium, and SDS-PAGE assessed protein expression after induction of protein expression. Three different methods did protein purification; in the first one, metal, ion affinity chromatography (IMAC) technique was used. In the second solution, first, by filtration with ammonium sulfate, the purification was carried out, and then by affinity purification, chromatography continued. In the third solution, hydrophobic chromatography was used to purify the streptokinase protein. The purity of ophthalmic purity was 93.2%, and the purity of hydrophobic purity was about 90.4%, whereas the combination of pre-treatment with ammonium sulfate and the purity of the ophthalmic method did not achieve more than 88%.In general, the results of this study show that the IMAC method is more suitable as a final method in the process of streptokinase purification than the other two approaches.
Effect of Dietary Energy Density on Increasing Blood Glucose Pattern and Hunger-Satiety Sensation Ni Luh Putu Ayu Putri Sariningrat1, Purwo Sri Rejeki1, Irfiansyah Irwadi1
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3384

Abstract

Background: There was no data how these food density could effect on glucose and visual analog levels based on hunger-filled scales in Indonesian population. Objective To determine the effect of food energy density on glucose levels and hunger-satiety sensation. Material and Methods: Seventeen women 18-22 years of age with BMI> 25, were given low energy density breakfast (n = 9) and high energy density (n = 7). The subjects were fasted for 10 hours, fasting blood glucose levels was measured as well as hunger-satiety sensation with a visual analog scale (VAS), prior to treatment. Breakfast was started at 08.00 a.m chew up to 32 times for 15 minutes. Blood glucose levels and VAS measurement were taken back in 2 hours and 4 hours afterward. Result: There was a significant differences in glucose levels between 4 hours postpandrial and 2 hours postpandrial (p = 0.031) and also between 4 hours postpandrial and fasting state (p = 0.042) in both groups. Analysis of hunger level VAS (p = 0.02) and satiety level VAS (0.04) at 4 hours postpandrial also differ significantly. Correlation analysis between hunger level VAS and blood glucose was different significantly (p = 0.01) with r = -0.59. Conclusions: The low energy density foods produce a pattern of increasing blood glucose levels were more stable, thus, more able to suppress the sensation of hunger than high energy density.
Effect of Phenytoin Usage Duration Against Hs-Crp Levels in Epilepsy Patients Ratna Wajiayanti1, Kurnia Kusumastuti1
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3385

Abstract

Background: Patients with epilepsy have a higher risk of death than the normal population. Epilepsy patients have increased mortality due to cardiovascular disease with standardized mortality ratios ranged between 1.2 and 2.5. The incidence of non-fatal coronary heart disease also increased significantly between 34% and 63%. Atherosclerosis as an inflammatory state has an important biomarker namely hs-CRP. Longterm use of phenytoin will have an effect on hs-CRP. hs-CRP is an atherosclerotic biomarker with a better cardiovascular predictor than blood lipid and homocysteine levels Methods: This study was conducted in epilepsy patients who fulfill ESR the criteria of inclusion and exclusion in Outpatient Unit of Dr. Soetomo General Hospital from October 2014 to April 2015. Patients were divided into a control group and case group. The control group was patients with hs-CRP levels <1.7 meanwhile, control group was >1.7. Tracking of phenytoin usage duration was performed in both groups. Results: Thirty-four subjects were enrolESR in this study which consisted of 21 males (61.76%) and 13 females (38.23%). The mean age of subjects in the case group was 31.6 + 12.6 years and control group was 26.52 + 11.3. Data of phenytoin usage duration and hs-CRP levels were analyzed. Conclusion: There was no significant difference between hs-CRP levels on phenytoin usage duration of >2 years and <2 years with p = 0.290
Comparison of Clinical Severity Improvement Degree between Acute Thrombotic Stroke Patients with Low and High Matrix Metalloproteinase-9 Levels Muhamad Hamdan1, Hendro Susilo, Paulus Sugianto1, A. Firdaus Sami1, Mohammad Saiful Ardhi1, Sita Set
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3387

Abstract

Background: Stroke is a cause of disability and dependency in both humanity and economic. Studies on the association of Matrix metallopeptidase 9 (MMP-9) levels with improved clinical severity are currently limited. Objectives: To determine the improvement of clinical severity in acute thrombotic stroke patients with high and low MMP-9 levels. Methods: Patients acute thrombotic stroke were grouped into low and high MMP-9 levels. MMP-9 levels were considered low when <840 ng/mL and high when ?840 ng/mL. Clinical severity improvement was assessed using the ?NIHSS scale. Results: Eighty subjects were enrolled that consists of clinical severity improved patients with lower MMP9 (37.9%) that higher than high MMP-9 (21.6%). This difference was not statistically significant (p = 0.115). Conclusion: There was no difference in clinical severity improvement in patients with acute thrombotic stroke with low MMP-9 levels in blood serum compared to high MMP-9 levels.

Page 66 of 550 | Total Record : 5497

 64   65   66   67   68 

Filter by Year

2020 2022


Reset
Filter By Issues
All Issue Vol. 16 No. 3 (2022): Indian Journal of Forensic Medicine and Toxicology Vol. 16 No. 2 (2022): Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 1 (2022): Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 1 (2021): Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 3 (2020): Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 1 (2020): Indian Journal of Forensic Medicine & Toxicology More Issue