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Jl. JA Suprapto No. 2 Kec. Klojen Malang 65112, Indonesia. Laboratory of Internal Medicine, Department of Internal Medicine, Faculty of Medicine, dr. Saiful Anwar General Hospital, IRNA 1 Building 2nd Floor
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INDONESIA
CRJIM (Clinical and Research Journal in Internal Medicine)
Published by Universitas Brawijaya
ISSN : 27235130     EISSN : 27235122     DOI : https://doi.org/10.21776/ub.crjim
Core Subject : Health, Science, Education,
Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Other
Clinical and Research Journal in Internal Medicine is the official open access journal of Internal Medicine Research Center, Department of Internal Medicine, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia. It publishes articles two times per year. It is a peer reviewed publication of Indonesian Internal Medicine journals and accepting articles for publication from around the world. CRJIM only publishes articles in the English version. The objective of this journal is to publish the selected clinical and basic research relevant to Internal Medicine. It covers the following topics, nephrology, endocrinology, metabolic, and diabetes, rheumatology, geriatrics, tropic infection, hematology oncology. CRJIM publishes original researches, reviews, brief reports, editorial, case series, case reports, and commentary. Additionally, it also considers publishing animal studies relevant to Internal Medicine topic. It is an international journal dedicated to providing new information that could give new insight for alternative solutions, diagnosis, therapy and prevention for researchers and practitioners in Internal Medicine.
Arjuna Subject : Kedokteran - Kedokteran Internal
Articles 93 Documents
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Navigating the Challenges of Clinical Scoring Systems in Thyroid Disease Rosandi, Rulli
Clinical and Research Journal in Internal Medicine Vol. 4 No. 1 (2023): Volume 4 No 1, May 2023
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.crjim.2023.004.01.1

Abstract

The Relationship between Increased Transaminase Enzyme Levels on Severity and Mortality of COVID-19 Patients treated at RSUD Dr. Saiful Anwar Malang Supriono Supriono; Nadina Zerlinda Mustamsir
Clinical and Research Journal in Internal Medicine Vol. 3 No. 1 (2022): The First Issue of Third Year
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.crjim.2022.003.01.5

Abstract

Background: The involvement of the liver in COVID-19 is not yet well understood, but several studies have suggested an association between elevated liver transaminases and the severity and mortality of COVID-19. Aim: This study aims to analyze the liver enzyme profiles of COVID-19 patients and determine the correlation between the severity of COVID-19 with the risk of mortality. Methods: The study was an observational study with case-control analysis. It was conducted between August 1, 2020, and October 31, 2020. The samples were collected consecutively based on the order of hospitalized research subjects in RSUD dr. Saiful Anwar Malang, East Java, Indonesia and were handed by the department of internal medicine. RT-PCR was used to confirm the diagnosis of COVID-19. The collected and grouped data was presented in tabulated form, and statistical analysis was carried out using a non-parametric analysis test with the Chi-Square Test method. Results: The study found that 51.4% of patients had elevated AST (Aspartate transaminase) levels, and 41.8% had elevated ALT (alanine aminotransferase) levels. AST and ALT data showed the severity and mortality variable's probability value (p-value) was < 0.005. Conclusion: This study's results indicated a significant relationship between increased transaminase enzymes with the severity and mortality rate of COVID-19 patients.
Case Report: CMML in Young Age which Transformed to AML Anggraini, Wilujeng; Brahmantyo, Herwindo
Clinical and Research Journal in Internal Medicine Vol. 4 No. 2 (2023): Volume 4 No 2, November 2023
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.crjim.2023.004.02.08

Abstract

CMML (Chronic Myelomonocytic Leukemia) is a rare type of blood cancer that characterized with the presents of monocytes in the blood. 1,2 According to WHO it is categorized as overlapped manifestation of MDS (Myelodysplastic Syndrome) and MPD (Myeloproliferative Disease) or MPN (Myeloproliferative Neoplasm). 2,3 The origin cause of CMML is gene mutation on TET2 (60 %), SRSF2 (50 %), ASLX1 (40 %), and RAS (30 %). 1,3,4 Men are predominantly affected with incidence peak between 71 and 74 years of age, and the prevalence on young adult are very rare and considered to be closely related to the presence of gene mutations in ASLX1. 1,3,5 From several case reports, there were 63 % of CMML patients changed into secondary AML within 1-5 years due to somatic gene mutations in the ASLX1. 2,3,4,6 In this case, we report a 21-year-old male who is diagnosed with CMML and eventually transformed to AML.
The Difference in Obesity Between Adults and Elderly with Knee Osteoarthritis Pradigo, Raynald; Tarigan, Ricky
Clinical and Research Journal in Internal Medicine Vol. 4 No. 2 (2023): Volume 4 No 2, November 2023
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.crjim.2023.004.02.02

Abstract

Background: Knee osteoarthritis (KOA) is one of the most common diseases of arthritis. The increase in KOA prevalence is also affected by the increase in obesity prevalence as one of the KOA risk factors. Aim: To see the difference in obesity association with KOA between adults and the elderly. Methods: The study design is analytic cross-sectional. 102 cases and controls data each are collected from Tarempa public health center (Phc) medical records by simple random sampling using a random number generator. Data taken is the latest patient visit record in the form of name, age, gender, weight, and height. Data are then analyzed using SPSS. This study's ethical clearance is accepted by the ethic committee faculty of medicine University of Sumatera Utara. Results: 59 (28.9%) men and 83 (71.1%) women participated in this study. The mean age of KOA subjects is 57.5 ± 11,4 with the most age range being 50-59 years old (38.2%). 71 (69.6%) KOA subjects are obese. The results of data analysis show that people ≥ 50 y.o with obesity were at 2.7 times more risk of suffering KOA than the normoweight or overweight people. There is no association between obesity and KOA in people under 50 years old. Conclusion: The risk of obesity developing into knee OA increased with age
A Comprehensive Management of Geriatric Syndrome in Level Two Health Facilities: Comprehensive Management of Geriatric Syndrome in Level Two Health Facilities Endah, Felia; Ningrum, Putu; Lusiana
Clinical and Research Journal in Internal Medicine Vol. 5 No. 1 (2024): Volume 5 No 1, May 2024
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.crjim.2024.005.01.10

Abstract

Background: The elderly population is increasing every year, especially in developing countries. Geriatric syndrome is a condition where there is a disturbance in the multifactorial system in the elderly due to decreased function. Case: Woman, 85 years old, came with the main complaint of weakness, accompanied by not wanting to eat and drink since 3 days. The patient could not sleep for 2 days, coughed up phlegm since 1 month ago, accompanied by shortness of breath. One week ago the patient complained of liquid bowel movements accompanied by mucus and dregs. The patient has a history of high blood pressure and was diagnosed with stage III heart failure. From physical examination, GCS E4V4M5, blood pressure 130/80, pulse 72x/m, respiration 20x/m, temperature 37 C, oxygen saturation 94%, anemic conjunctiva, rhonchi in both lung fields, epigastric tenderness, non-pitting upper leg edema. Laboratory examination, Hb 8.0 gr/dL on the second day to 6.7 gr/dL, LED 72 mm/hour. AP chest photo shows consolidation in the middle zone of the right lung and left lower zone, increased vascular pattern with chepalization, CTR 72%. The patient was given initial management of 40 mg omeprazole injection and 4 mg ondansetron. Discussion and conclusion: Based on the results of the anamnesis, physical examination, and support examination, the patient's complaints constitute a geriatric syndrome. The management provided includes medical management to deal with systemic complaints as well as educating the family about the patient's condition. Keywords: Elderly, geriatric syndrome
Identify The Type of Pleural Effusion with Lung Ultrasound: A Case Report and State-of-Art Ielo, Simone; Fratini, Antonio; Amante, Edoardo; Spinelli, Marcello
Clinical and Research Journal in Internal Medicine Vol. 4 No. 2 (2023): Volume 4 No 2, November 2023
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.crjim.2023.004.02.10

Abstract

Pleural effusion is the most common pleural pathology and is seen in a large group of patients admitted to internal medicine wards.The purpose of this state of art literature review is to describe the various ultrasound findings that can be observed, to highlight the ability of lung ultrasound to facilitate differential diagnosis by pointing to a specific type of effusion and its cause.To this end, the clinical case description aims to demonstrate the above and promote the use of bedside lung ultrasound by considering this technique as the fifth physical examination technique after inspection, palpation, percussion and auscultation.
Clinical Clue and Predictive Blood Count of Hemodialysis Cathether-Related Infection: Case Series Vanessa, Nadya; Primiawan, Tatag
Clinical and Research Journal in Internal Medicine Vol. 4 No. 2 (2023): Volume 4 No 2, November 2023
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.crjim.2023.004.02.09

Abstract

Most patients with chronic kidney disease (CKD) require renal replacement therapy. Majority of hemodialysis initiation is done through a dialysis catheter access. The use of catheters double lumen (CDL) for hemodialysis has several potential complications, including infection. Catheter related bloodstream infection (CRBSI) is associated with increased morbidity and mortality in CKD patients. CRBSI therapy should not be delayed, including delays due to waiting for culture results to confirm the diagnosis. Several studies have reported the use of clinical findings and routine blood count parameters to predict CRBSI. This case series reported three cases with suspected CRBSI consisting of one woman and two men with mean age of 44.67 ± 8.21 years, mean catheter days 13 ± 6.97, and mean hemodialysis duration of 10.5 ± 13.79 month. Diagnosis CRBSI was suspected from clinical clue, i.e symptoms such as fever and chills, pain at the CDL site, and physical examination i.e body temperature and local CDL site signs. Laboratory parameters in this case series reported elevations for PLR, NLR and SIRI supporting the suspicion of bloodstream infection. All patients in this case series improved after CDL removal and antibiotics therapy. Investigation of clinical findings and routine blood count parameters can be an alternative diagnosis of CRBSI that enables prompt treatment in areas with limited facilities. Keywords: chronic kidney disease, catheter related bloodstream infection, diagnosis
The Effectiveness of Depression Intervention and Risk Factor in Geriatrics: a Systematic Review Sunarti, Sri; Rakha, Muhammad; Harumbay, Nysrina; Harahap, M.; Hidayat, Rizal
Clinical and Research Journal in Internal Medicine Vol. 4 No. 2 (2023): Volume 4 No 2, November 2023
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.crjim.2023.004.02.03

Abstract

Background: Increasing age is a new challenge in today's health services. With increasing age, the physiological function will decrease. Not only infectious diseases and systemic diseases, but the elderly are also prone to social problems and mental health problems, including depression. Depression is the most common mental illness in the elderly. Depression can significantly reduce the quality of life of the elderly. Aim: To obtain a deeper understanding of interventions and risk factors for depression in geriatrics.Methods: Literature searches were taken from Science Direct, Pubmed, and Google Scholar from 2020 - 2022, in which 8 eligible articles were found. The keywords used in the search were "depression", "elderly", "elder", and "geriatric". Article quality was evaluated using the CASP checklist.Results: The results of the articles were obtained from several countries. The interventions carried out can be grouped into several categories, namely interventions in the form of physical activity therapy, music therapy, psychoeducation, cognitive change, and problem-solving. This review helps inform several interventions that can be performed on the elderly and factors that support the success of interventions.Conclusion: There are several risk factors for depression in the elderly, by performing several intervention methods in the elderly, depression can reduce the risk of depression.
Differences in Nutritional Status and Quality of Life in Hemodialysis Patients Compared to CAPD Kosasih, Angelia; Samsu, Nur; Rifa'i, Achmad
Clinical and Research Journal in Internal Medicine Vol. 5 No. 1 (2024): Volume 5 No 1, May 2024
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.crjim.2024.005.01.02

Abstract

Background: Patients with chronic kidney disease who undergo hemodialysis and CAPD (Continous Ambulatory Peritoneal Dialysis) modalities often experience disturbances in nutritional status and quality of life. The condition is affected by the chosen modalities and duration. Aim: This study assesses the differences in nutritional status and quality of life in individuals undergoing hemodialysis therapy with a duration of 4-hour, hemodialysis with a duration of 5-hour, and CAPD in order to determine the best modalities for patients with chronic kidney disease. Methods: Data were collected with cross-sectional from patients with chronic kidney disease at the hemodialysis polyclinic at RSUD dr. Saiful Anwar Malang, Panti Nirmala Hospital Malang, Wava Husada Kepanjen Hospital, and the CAPD polyclinic at RSUD dr. Saiful Anwar Malang. Classified into CAPD group, 4-hour hemodialysis group, and 5-hour hemodialysis group. Assessment with a questionnaire consisting of the patient’s baseline characteristics, subjective global assessment (SGA), and SF-36 are used to assess and analyze differences in nutritional status and quality of life of patients with chronic kidney disease against the selected dialysis modality. Results: The physical health of the 5-hour hemodialysis group showed significant results compared to the 4-hour hemodialysis and CAPD (p <0.05). Mental health in the 5-hour hemodialysis procedure showed significant results compared to the 4-hour hemodialysis and CAPD (p <0.05). The nutritional status of 5-hour of hemodialysis was better than 4-hour of hemodialysis and CAPD (p<0.05). Conclusion: Hemodialysis with a duration of 5-hour has a better nutritional status and quality of life compared to a duration of 4-hour or CAPD.
RETRACTED: Lung Abnormalities in Liver Cirrhosis Muli Yaman; Mustika, Syifa
Clinical and Research Journal in Internal Medicine Vol. 4 No. 2 (2023): Volume 4 No 2, November 2023
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.crjim.2023.004.02.06

Abstract

Clinical and Research Journal in Internal Medicne has retracted article titled: "Lung Abnormalities in Liver Cirrhosis" by Muli Yaman, and Syifa Mustika, from Vol. 4, No. 2 (2023) since there has been similar publication found in Current Internal Medicine Research and Practice Surabaya Journal (CIMRJ) Vol. 4, No. 1 (January 2023).This retraction announcement is necessary to maintain publication ethics.

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