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INDONESIA
Jurnal Farmasi dan Sains Indonesia (JFSI)
Published by Sekolah Tinggi Ilmu Farmasi Nusaputera
ISSN : 26219360     EISSN : 26863529     DOI : https://doi.org/10.52216
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Medicine & Pharmacology Neuroscience
Focus and Scope Jurnal Farmasi & Sains Indonesia is an open-access journal that published twice a year by Sekolah Tinggi Ilmu Farmasi Nusaputera. This journal is a media of research publication on all aspects of pharmaceutical & science that is innovative, creative, original and based on scientific. Articles published in this journal about drug discovery, drug delivery systems and drug development with specific field include: 1. Medicinal chemistry 2. Pharmacology 3. Pharmacokinetics 4. Pharmacodynamics 5. Pharmaceutical analysis 6. Drug delivery systems 7. Pharmaceutical technology 8. Pharmaceutical biotechnology 9. Herbal medicines and active components 10. Clinical evaluation of the medicine
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 24 Documents
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Search results for , issue "Vol 8 No 2 (2025)" : 24 Documents clear
Identifikasi Bahan Kimia Obat dalam Sediaan Jamu Pegal Linu Menggunakan Metode Spektroskopi Inframerah Christina, Odilia Dea; Yudhantara, Sandi Mahesa; Solichah, Ayu Ina; Bulu, Atalia Tamo Ina
Jurnal Farmasi & Sains Indonesia Vol 8 No 2 (2025)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol8no2p150-156

Abstract

Pegel linu herbal medicine is one of the traditional remedies widely consumed by the community to relieve pain and fatigue. The high market demand, particularly through online marketplaces, has the potential to be misused by irresponsible producers by illegally adding pharmaceutical chemicals to enhance therapeutic effects. This study aimed to identify the presence of pharmaceutical adulterants, namely paracetamol, sodium diclofenac, and dexamethasone, in peg el linu herbal medicines circulating in the market using Fourier Transform Infrared (FTIR) spectroscopy. Ten herbal medicine samples were selected using purposive sampling based on criteria such as the absence of distribution permit numbers or the presence of exaggerated therapeutic claims. The samples were prepared through extraction procedures and analyzed using FTIR-ATR by comparing the sample spectra with reference standards. The results showed that one sample tested positive for paracetamol and one sample tested positive for dexamethasone, while sodium diclofenac was not detected in any of the samples. The presence of pharmaceutical adulterants was identified based on the appearance of characteristic functional groups such as O–H, N–H, and C=O at specific wavenumbers. These findings indicate that some peg el linu herbal medicines circulating in the market still contain illegal pharmaceutical adulterants, which may pose potential health risks to consumers.
Konseling Apoteker Sebagai Upaya Meningkatkan Kepuasan Pasien Tukak Lambung Di Apotek Kimia Farma Indriani, Syifa Alifia; Johar, Hendra Farma
Jurnal Farmasi & Sains Indonesia Vol 8 No 2 (2025)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol8no2p176-184

Abstract

Pharmaceutical services refer to how "patient care" is delivered. Pharmacist counseling is a crucial component aimed at improving therapeutic understanding and patient satisfaction, particularly in patients with peptic ulcers, who require discipline and adherence to appropriate medication. This study aimed to assess patient satisfaction with services before and after pharmacist counseling regarding peptic ulcers at Kimia Farma pharmacies. The sampling technique used was purposive sampling for peptic ulcer patients, resulting in a sample size of 100 respondents. This study employed a one-group pre-test-post-test and quasi-experimental method. Data analysis used SPSS 29 for Windows and Microsoft Office Excel 2016 to test SERVQUAL values, normality tests, and the Wilcoxon test. The Wilcoxon test demonstrated a significant difference in patient perceptions of the services received before and after pharmacist counseling. The Wilcoxon test also demonstrated a significant difference between expected and actual pharmacy services before and after pharmacist counseling. This indicates that pharmacist counseling has a significant impact on improving patient perceptions and satisfaction with the services received.
Formulasi Lilin Aromaterapi Kombinasi Minyak Atsiri Kulit Jeruk Nipis (Citrus aurantifolia) Dan Bunga Melati (Jasminum sambac L.) Dengan Cera Alba Sebagai Basis Sudarsono, Agustina Putri Pitarisa; Ramanda, Aulia Avida
Jurnal Farmasi & Sains Indonesia Vol 8 No 2 (2025)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol8no2p163-169

Abstract

Aromatherapy is an alternative treatment method that utilizes volatile essential oils to provide therapeutic Aromatherapy is an alternative treatment method using volatile essential oils to provide therapeutic effects such as relaxation and improved blood circulation. Lime peel essential oil contains limonene as a repellent, while jasmine flower essential oil contains linalool that promotes calmness. Cera alba is used as a candle base to support structure and burning stability. This study aimed to evaluate the effect of combining lime peel and jasmine essential oils with varying cera alba concentrations on the physical properties and acceptability of aromatherapy candles. Five candle formulas were prepared: F0 without essential oils as a control, and F1–F4 with varying concentrations of lime peel (0.1–0.3%) and jasmine (7–9%). Evaluations included organoleptic tests, melting point, burning time, and hedonic tests by panelists. Results showed that essential oil combinations influenced melting point, burning time, and aroma. Formula F3 (lime peel 0.2%, jasmine 7%, cera alba 82.8%) met all physical standards with an average melting point of 57°C, burning time of 168.67 minutes, and was most preferred by panelists. Statistical analysis confirmed normality and homogeneity, and post hoc tests (p < 0.05) indicated significant differences among formulas, demonstrating that essential oil combination and cera alba concentration determine candle quality and panelist preference.
Uji Aktivitas Antinosiseptik dan Analgetik Kombinasi Ekstrak Etanol Rumput Teki (Cyperus Rotundus L.) dan Ekstrak Etanol Daun Tapak Liman (Elephantopus Scaber L.) pada Mencit Putih Galur Swiss: Antinosiseptik dan Analgetik Ekstrak Etanol Rumput Teki dan Daun Tapak Liman Palupi, Poppy Diah; Leki, Karol Giovani Battista
Jurnal Farmasi & Sains Indonesia Vol 8 No 2 (2025)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol8no2p170-175

Abstract

Pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage. Medicinal plants have been increasingly explored as alternative analgesic agents due to their bioactive compounds. Cyperus rotundus L. contains flavonoids reported to possess analgesic properties, while Elephantopus scaber L. has traditionally been used for pain relief. This study aimed to evaluate the analgesic and antinociceptive activities of a combined ethanolic extract of Cyperus rotundus and Elephantopus scaber in male Swiss mice. This experimental laboratory study involved 10 groups of male Swiss mice (n=5 per group). Analgesic activity was assessed using the tail-flick test, while antinociceptive activity was evaluated using the hot plate test. Negative controls received CMC-Na 0.5% but were exposed to nociceptive stimuli. Positive controls received mefenamic acid (500 mg/kg BW) for analgesic testing and tramadol (50 mg/kg BW) for antinociceptive testing. Treatment groups received combined ethanolic extracts (ERTDTL) at doses of 700/400, 900/600, and 1100/800 mg/kg BW. Pain response latency was recorded 30 minutes after treatment. Data were analyzed using one-way ANOVA followed by the Dunnett post hoc test. The combined extract demonstrated significant analgesic and antinociceptive effects at all tested doses in mice subjected to thermal nociceptive stimuli. These findings suggest that the combination of extracts from Cyperus rotundus and Elephantopus scaber has potential as a natural analgesic agent.

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