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Narra J
Published by PT Narra Sains Indonesia
ISSN : -     EISSN : 28072618     DOI : https://doi.org/10.52225/narraj
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
Narra J is a multidisciplinary journal and it is published three times (April, August, December) a year. The objective is to promote articles on infection, public health, global health, tropical infection, one health and diseases in tropics. Narra J publishes original research work across all disciplines of medicine and allied sciences, related to infection, public health, global health, tropical infection, one health and diseases in tropics. The journal publishes Original articles, Short Report, Review articles, and Letters to the Editor. All articles published in Narra J are peer-reviewed and published online for immediate access and citation. Narra J publishes the primary research papers, review articles, short communications and letters on topics but not limited to: Public health Global health Infection Tropical diseases One health Biomedical sciences Epidemiology and clinical epidemiology Molecular biology Environmental health Microbiology Pharmacological sciences Diseases in tropics
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 565 Documents
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Determinants of intrauterine device use among reproductive-age women in a province implementing Islamic Sharia law in Indonesia: An application of the theory of planned behavior Purnama, Dean R.; Dewi, Tgk. Puspa; Rusnaidi, Rusnaidi; Utami, Niken A.; Aditya, Rizka; Suhanda, Rachmad
Narra J Vol. 6 No. 1 (2026): April 2026
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v6i1.3025

Abstract

The utilization of the intrauterine device (IUD) in Indonesia remains low at 3.9%, despite its high effectiveness (99.4%) and designation as a national family planning priority, suggesting the presence of psychosocial barriers influencing contraceptive behavior among women of reproductive age. This study aimed to analyze psychosocial factors influencing IUD use behavior based on the theory of planned behavior, including attitudes, subjective norms, perceived behavioral control, actual behavioral control, and intention, in Banda Aceh—the only province in Indonesia implementing holistic Sharia law. A quantitative cross-sectional study was conducted among women of reproductive age from six urban public health centers using cluster random sampling. Data were collected through face-to-face interviews using a structured TPB-based questionnaire validated for reliability. Statistical analyses included linear regression and binary logistic regression with a significance level set at p<0.05. A total of 442 women were included in the final analysis. Attitude toward IUD use, subjective norms, and perceived behavioral control were all significantly associated with intention to use an IUD, all had p<0.001. Attitudes toward IUD use (B=0.410; p<0.001; R²=0.213), subjective norms (B=0.552; p<0.001; R²=0.413), perceived behavioral control (B=0.273; p<0.001; R²=0.255), and actual behavioral control (B=0.273; p<0.001; R²=0.255) were all significantly associated with IUD use behavior. Intention to use an IUD emerged as the strongest predictor of IUD use behavior (B=0.780; p<0.001; R²=0.566). Intention to use an IUD emerged as the strongest predictor of IUD use behavior (B=0.78; p<0.001; R²=0.56). This study highlights that all intention was shaped by positive attitudes, strong subjective norms, and a high level of behavioral control. Efforts to increase IUD use should therefore focus on educational interventions, strengthening partner and social support, and improving the accessibility and quality of long-acting contraceptive services.
Reality of implementation, barriers, and local-based innovations of stunting reduction programs in Papua region, Indonesia: A systematic review Mustasmara, Rida; Hariyanti, Tita; LPH. Mastuti, Ni
Narra J Vol. 6 No. 1 (2026): April 2026
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v6i1.3023

Abstract

Stunting remains a major public health problem in Indonesia, with a disproportionate burden in Papua, where many districts are classified as 3T regions (frontier, outermost, and least-developed areas) characterized by limited infrastructure, restricted access to services, and distinct socio-cultural challenges. The aim of this study was to comprehensively examine the implementation of stunting reduction programs in Papua’s 3T regions, including program delivery, barriers, and local innovations, through a systematic review. Articles were identified through searches of five major databases and grey literature and were selected using the PRISMA framework. Eligible studies reported on program implementation, barriers, risk factors, and/or strategies related to stunting reduction in Papua. A total of 45 studies met the inclusion criteria and were synthesized using a thematic narrative approach. The review indicated that stunting reduction efforts in Papua have included both nutrition-specific and nutrition-sensitive interventions, supported by the establishment of acceleration teams, the use of integrated health service posts (Posyandu), supplementary feeding, micronutrient supplementation, and the 1,000 days of life initiative. However, program effectiveness is constrained by geographical isolation, health workforce shortages, weak cross-sectoral coordination, and a persistent gap between national policy design and local implementation capacity. Frequently reported risk factors included suboptimal caregiving practices, inadequate dietary intake, recurrent infections, poor sanitation, poverty, and a double burden borne by women, all of which impede program success. Conversely, locally grounded strategies—such as local food-based interventions, strengthening cadres and traditional leaders, community education, and pentahelix collaboration—emerged as more contextually appropriate and community-accepted approaches. Overall, these findings underscore the need to adapt policies to local conditions, strengthen convergence governance, and expand long-term evaluative research to improve the effectiveness and sustainability of stunting interventions in Papua’s 3T regions.
Oxidative stress as a converging mechanism of aging and neurodegeneration: From molecular pathways to therapeutic targets Faradilla, Meutia A.; Anastasya, Karina S.; Yastani, Deasyka; Yohana, Yohana; Tungka, Endrico X.; Suweino, Suweino
Narra J Vol. 6 No. 1 (2026): April 2026
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v6i1.3042

Abstract

Aging is the primary risk factor for major neurodegenerative disorders, yet the precise molecular links between biological aging and progressive neuronal loss remain complex. Oxidative stress, defined as an imbalance between the production of reactive oxygen species (ROS) and antioxidant defenses, has emerged as a central converging mechanism driving both processes. This review aims to synthesize current evidence demonstrating how chronic redox imbalance drives cellular senescence and neuronal vulnerability through mitochondrial dysfunction, lipid peroxidation, and oxidative protein damage. These insights underscore how sustained oxidative insults promote the misfolding and aggregation of disease-defining proteins, including amyloid-beta in Alzheimer’s disease and α-synuclein in Parkinson’s disease, thereby amplifying neuroinflammation, synaptic dysfunction, and bioenergetic failure. Furthermore, antioxidant-based therapeutic strategies are critically reassessed, highlighting a paradigm shift from non-specific radical scavenging toward targeted modulation of endogenous defense systems, particularly NRF2 signaling and mitochondria-directed antioxidants. By integrating molecular mechanisms with translational perspectives, this review integrates molecular, cellular, and translational evidence to explain how oxidative stress links biological aging to neurodegenerative disorders such as Alzheimer’s and Parkinson’s diseases.
Relative validity of a self‑dietary assessment nutrition application compared with a 3‑day food record in non‑dialysis chronic kidney disease: A prospective study Arayangkoon, Chantisa; Siriyong, Patchanon
Narra J Vol. 6 No. 1 (2026): April 2026
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v6i1.3071

Abstract

Accurate and repeated dietary assessment is essential for nutritional management in chronic kidney disease (CKD); however, conventional methods, such as the 3-day food record, are burdensome for routine clinical use. Digital self-administered dietary assessment tools may offer a practical alternative; however, validation data in non-dialysis CKD, particularly among Asian populations, remain limited. This study aimed to evaluate the relative validity of a locally adapted digital self-dietary assessment application (Nutrirodcal) compared with a 3-day food record in patients with non-dialysis CKD. This prospective single-center study enrolled adults with non-dialysis CKD stages 3–5. Participants completed both a 3-day food record (reference method) and Nutrirodcal every 4 weeks for 12 weeks. Correlations between the two methods were assessed for energy, macronutrients, minerals, and fluid intake. Changes in nutritional status, biochemical parameters, and body composition were assessed as secondary outcomes. Twenty participants completed the study. At week 12, Nutrirodcal showed moderate-to-strong correlations with the 3-day food record for energy, protein, sodium, potassium, calcium, and phosphorus intake (Spearman r=0.50–0.65; all p<0.05). Correlations for fluid intake were weak at weeks 4 and 12 but reached a moderate and statistically significant level at week 8 (r=0.55, p=0.012). Over the study period, body mass index decreased significantly without deterioration in serum albumin or kidney function, while other biochemical and body composition parameters remained stable. Nutrirodcal demonstrated acceptable relative validity for assessing key nutrient intakes relevant to CKD management compared with a 3-day food record. This Thai-adapted digital tool may support repeated dietary monitoring and patient engagement in non-dialysis CKD care, although dietitian oversight remains essential, particularly for fluid intake assessment.
Determinant of recovery, recurrence and recurrence-free interval of condyloma acuminata: A five-year cross-sectional data from a provincial referral hospital in Indonesia Prasetyadi Mawardi; Maulana, Muhammad I.; Ellistasari, Endra Y.; Primisawitri, Pratiwi P.; Purnamasari, Rina
Narra J Vol. 6 No. 1 (2026): April 2026
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v6i1.3069

Abstract

Condyloma acuminata is a common sexually transmitted disease caused by human papillomavirus infection and is characterized by frequent recurrence despite available therapies. This study evaluated recovery, recurrence, and recurrence-free interval across therapeutic modalities among condyloma acuminata outpatients at Dr. Moewardi Regional General Hospital, Surakarta, Indonesia, from January 2020 to December 2024. Using a cross-sectional analysis of medical records, 132 eligible patients were included and analyzed with bivariate tests. Treatment modality was not significantly associated with recovery (p=0.157), although recovery was highest with trichloroacetic acid (71.2%), followed by excision (66.7%), combination therapy (trichloroacetic acid + cryotherapy) (64.7%), and cryotherapy alone (33.3%). In bivariate analysis, type of therapy (p=0.025) as well as type of condyloma (p<0.001), sexual orientation (p=0.019), and HIV status were associated with recurrence, with the highest recurrence observed after excision (42.4%) and the lowest after cryotherapy alone (11.1%). Mean recurrence-free interval varied across modalities (cryotherapy 8.00±0.00; trichloroacetic acid (TCA) 15.92±28.49; excision 18.93±13.64; combination therapy 27.50±36.67 weeks), with the longest interval observed in the combination group. However, statistical analysis revealed that only types of condyloma, sexual orientation, and HIV status were associated with the mean recurrence time. Overall, recovery and recurrence patterns differed descriptively across treatment modalities, with excision showing the highest recurrence and cryotherapy alone the lowest. Recurrence outcomes varied according to treatment modality; however, no significant association was observed between therapy type and recurrence-free interval.

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