Jurnal Ilmu Kedokteran (Journal of Medical Science)
Journal of Medical Science receives a script from health and medical lecturer, undergraduate, residents, hospital staff and those who interested in writing scientific papers. The scientific articles posted on JIK include: literature reviews, research article, case report and EBCR (Evidence Based Case Report). Article preferably basic science of medicine and health.
Articles
255 Documents
<![CDATA[Uji Toksisitas Akut Ekstrak Etanol Daun Sapu Jagad (Isotoma longiflora (L) Presl.) pada Mencit Galur Mus muculus ]]>
<![CDATA[Ira Safitri]]>;
<![CDATA[Inayah Inayah]]>
<![CDATA[ Jurnal Ilmu Kedokteran Vol 4, No 1 (2010): Jurnal Ilmu Kedokteran ]]>
Publisher : <![CDATA[Fakultas Kedokteran Universitas Riau ]]>
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DOI: 10.26891/JIK.v4i1.2010.42-47
<![CDATA[Sapu Jagad (Isotoma longiflora (L) Presl.) plant has been empirically used as traditional medicine. Some studies showthat this plant has pharmacological effects as antibiotic, anticancer, and analgetic. It is of importance to conduct studyin finding out the safetiness of this plant as herbal medicine. Therefore, we conducted study to find out lethal dose ofits leaves on mice (Mus muculus) using acute toxicity test. Several doses have been given to certain groups to find outits effect including death. The extract has been given one time per oral. Then, we recorded the clinical signs and deathof mice until 14 days. The data was analyzed using probit analysis to measure LD50. This study shows that ethanolextract of Sapu Jagad leaves has LD50 12.610 mg/kgBW and toxicity of central nervous system proven by seizureending with death. As conclusion, this extract has toxicity especially to central nervous system.]]>
<![CDATA[Gambaran Penderita Filariasis di Kabupaten Meranti Provinsi Riau Periode 2009-2014 ]]>
<![CDATA[Esy Maryanti]]>;
<![CDATA[Andriyani Andriyani]]>;
<![CDATA[Suyanto Suyanto]]>
<![CDATA[ Jurnal Ilmu Kedokteran Vol 10, No 2 (2016): Jurnal Ilmu Kedokteran ]]>
Publisher : <![CDATA[Fakultas Kedokteran Universitas Riau ]]>
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DOI: 10.26891/JIK.v10i2.2016.112-120
<![CDATA[Filariasis is one of the health problems in Indonesia due to its long-term effect on permanent disability ifnot treated properly. The purpose of this study is to describe people with filariasis in Meranti District ofRiau Province 2009-2014. The methods is a descriptive retrospective cross-sectional study using medicalrecords of patients diagnosed with filariasis in hospitals and all health centers in the District of Meranti.The result showed 38 patients with filariasis, and the highest case of filariasis were in Puskesmas PulauMerbau (94.8%). Distribution by gender, age and type of occupation as follows: men by 71%, 86.8% of thesubject belong to the age group 15-64 years old, and 65.8% were outdoor workers, 52.6% of lymphedemawas reported and the location of lymphedema mostly found on each leg (18.4%). All lymphedema werebelong to all the stage not exceed stage III. All cases of filariasis in this study were managed according tothe standard treatment.]]>
<![CDATA[Luaran Kehamilan Dengan Sistemik Lupus Eritematosus ]]>
<![CDATA[Maya Savira]]>
<![CDATA[ Jurnal Ilmu Kedokteran Vol 5, No 2 (2011): Jurnal Ilmu Kedokteran ]]>
Publisher : <![CDATA[Fakultas Kedokteran Universitas Riau ]]>
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DOI: 10.26891/JIK.v5i2.2011.63-70
<![CDATA[Systemic lupus erythematosus often abbreviated to SLE or lupus, is a systemicautoimmune disease (or autoimmuneconnective tissue disease) that can affect any part ofthe body. As occurs in other autoimmune diseases, the immunesystem attacks the body’scells and tissue, resulting in inflammation and tissue damage. It is a type IIIhypersensitivityreaction caused by antibody-immune complex formation. Women with lupus are at risk for various complications ofpregnancy, and those with antiphospholipid antibodies may have an increased risk of miscarriage. Systemic lupuserythematosus increases the risk of spontaneous abortion, intrauterine fetal death, preeclampsia, intrauterine growthretardation, and preterm birth. The outcome for both mother and child is best when systemic lupus erythematosus hasbeen under good control for at least six months before pregnancy and when the kidney disease is in remission.]]>
<![CDATA[Taeniasis Solium dan Sistiserkosis pada Manusia ]]>
<![CDATA[Elva Susanty]]>
<![CDATA[ Jurnal Ilmu Kedokteran Vol 12, No 1 (2018): Jurnal Ilmu Kedokteran ]]>
Publisher : <![CDATA[Fakultas Kedokteran Universitas Riau ]]>
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DOI: 10.26891/JIK.v12i1.2018.1-6
<![CDATA[Taenia solium taeniasis (taeniasis) and cysticercosis in human are infectious diseases caused by pork tapeworm Taenia solium. They are zoonotic diseases and still a health problem in the world, especially in developing countries such as Indonesia. The prevalence of taeniasis and cysticercosis in Indonesia is still quite high at 2% - 48% with the highest prevalence in Papua. Human taeniasis can manifest as a asymptomatic or intestinal minimally symptomatic. Cysticercosis can involve of neural tissue (neurocysticercosis) may manifest epilepsy seizure, headache, neurological symptom, cognitive disabilities, and death. The habit of eating raw or undercooked pork, lack of sanitation, and a lack of supervision the slaughterhouse are some of the factors causing taeniasis and cysticercosis in human. Avoiding eating raw pork, cooking meat over temperature 54oC, supervision at slaughterhouses, and maintaining hygiene is a way to prevent taeniasis and cysticercosis, therefore it is necesarry to do more intensive programs to prevent and control the diseases.]]>
<![CDATA[Free Fibular Osteoseptocutaneus Flap for Reconstruction Giantameloblastoma ]]>
<![CDATA[Rachmat Wiardi]]>;
<![CDATA[Irra Rubianti W]]>
<![CDATA[ Jurnal Ilmu Kedokteran Vol 9, No 1 (2015): Jurnal Ilmu Kedokteran ]]>
Publisher : <![CDATA[Fakultas Kedokteran Universitas Riau ]]>
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DOI: 10.26891/JIK.v9i1.2015.47-53
<![CDATA[Ameloblastoma is a tumor originating from odontogenic epithelial cells. The tumor is located in the gray zone betweenbenign and malignant neoplasms. These tumors can occur at any age. Although traditionally divided as solid andcystic ameloblastoma, nearly all showed cystic changes. These tumors are invasive and have a very high recurrencerate. Ameloblastoma is an odontogenic tumor that is often found. These tumors are generally diagnosed in the fourthand fifth decade. Approximately 80% of these tumors occur in the jaw, with three-quarters are in the molar region andramus. Approximately 20% of them occurred in the premolar and incisivum. Operative therapy was elected a radicalresection of the affected parts of the jaw, followed by reconstruction. Bridging titanium plate can be used to replacepart of lost bone and serves as a means of reconstruction. Various methods of reconstruction of the mandible can bedone by using a bone graft from the calcaneus, fibula, ribs, scapula, iliac crest, or flap reconstruction. We report acase of male patients at entry RSHS Hospital May 11, 2010 18 years old with complaints arising the lump under thetongue ± 8 years ago, accompanied by difficulty eating, difficulty speaking, and shortness of breath. Patients in thediagnosis of ameloblastoma of the mandible on the basis of anatomic pathology examination. It was decided to do thereconstruction of segmental mandibulectomy and free fibular osteoseptocutaneous free flap with multiple osteotomy.Patients go home in improvement condition.]]>
<![CDATA[Profil Penderita Diare Anak Di Puskesmas Rawat Inap Pekanbaru ]]>
<![CDATA[Esy Maryanti]]>;
<![CDATA[Suri Dwi Lesmana]]>;
<![CDATA[Hendro Mandela]]>;
<![CDATA[Setri Herlina]]>
<![CDATA[ Jurnal Ilmu Kedokteran Vol 8, No 2 (2014): Jurnal Ilmu Kedokteran ]]>
Publisher : <![CDATA[Fakultas Kedokteran Universitas Riau ]]>
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DOI: 10.26891/JIK.v8i2.2014.101-105
<![CDATA[Diarrhea is one of the most frequent diseases of infants and children in the world. In developing countries, diarrheais still one of the major causes of morbidity and mortality in children. In 2009, the incidence of diarrhea in childrenin Pekanbaru there were more than 5-6 people per day. Pekanbaru is the densely populated city that is very easyoccurrence of diarrhea in children. Many factors affect the incidence of diarrhea in children, one of which is theenvironment, hygiene and nutritional status of children. This study aims to determined the profile of children withdiarrhea in Health Centers Inpatient Pekanbaru. A total of 96 patients of diarrhea in children Pekanbaru HealthCenter Inpatient obtained most of the male sex (54.2%), with the age of majority was especially toddlers aged 1-3years. Nutritional status in patients with diarrhea was generally a good. Stool characteristics in childhood diarrheapatients was mostly mushy, not slimy and does not bleed.]]>
<![CDATA[Epidemiologi Kriptosporidiosis ]]>
<![CDATA[Esy Maryanti]]>
<![CDATA[ Jurnal Ilmu Kedokteran Vol 5, No 1 (2011): Jurnal Ilmu Kedokteran ]]>
Publisher : <![CDATA[Fakultas Kedokteran Universitas Riau ]]>
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DOI: 10.26891/JIK.v5i1.2011.1-6
<![CDATA[Cryptosporidiosis is a disease caused by Cryptosporidium sp. Cryptosporidium sp. are single cell of coccidian caninfected human and animals. Cryptosporidiosis are considered a cause of emerging and opportunistic infections inhuman. Oocysts of Cryptosporidium are ovoid or spherical and 4 to 6 micrometers diameters. The parasite is located inthe brush border of the epithelial cells of the small intestine. Currently, eight species of Cryptosporidium are known toinfect human and there are two species, C parvum and C muris which most common species reported to infect childrenand immunocompromised patient especially AIDS patient with diarrhea.]]>
<![CDATA[Gambaran Histopatologi Paru Mencit (Mus musculus) Setelah Pemaparan Paraquat ]]>
<![CDATA[Aulia Wiradi]]>;
<![CDATA[Wiwit Ade Fidiawati]]>;
<![CDATA[Sri Melati Munir]]>
<![CDATA[ Jurnal Ilmu Kedokteran Vol 11, No 2 (2017): Jurnal Ilmu Kedokteran ]]>
Publisher : <![CDATA[Fakultas Kedokteran Universitas Riau ]]>
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DOI: 10.26891/JIK.v11i2.2017.7-11
<![CDATA[Paraquat destroys organs including lung. Purpose of this study was to determine the effect of paraquat on histopathologyof lung, exspecially fibrosis in mice (Mus musculus). This study was an experimental study with post-test only withcontrol design and using 15 mice as sample. Samples were divided into 5 groups consist of one control group and fourdifferent doses of paraquat treatment group (25 mg / kg / day, 50 mg / kg / day, 75 mg / kg / day and 100 mg / kg / day for7 days with spraying). Analysis of the data have used One-Way ANOVA then post-hoc test with tukey to assesseddifferences of each groups. The results showed increasing of lung fibrosis with increasing doses and have significantcorrelations (p = 0.000). In conclusion, there are significant changes in lung histopathology of mice (Mus musculus)after paraquat exposure for 7 days.]]>
<![CDATA[Pola Penggunaan Insulin Pada Pasien Diabetes Melitus Tipe 2 Rawat Inap Di Rumah Sakit X Pekanbaru Tahun 2014 ]]>
<![CDATA[Inayah Inayah]]>;
<![CDATA[M. Yulis Hamidy]]>;
<![CDATA[Roza Putri Rachma Yuki]]>
<![CDATA[ Jurnal Ilmu Kedokteran Vol 10, No 1 (2016): Jurnal Ilmu Kedokteran ]]>
Publisher : <![CDATA[Fakultas Kedokteran Universitas Riau ]]>
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DOI: 10.26891/JIK.v10i1.2016.38-43
<![CDATA[Insulin is one of pharmacological treatment of type 2 diabetes mellitus (DM). The aim of this study was to know thepattern of insulin use in hospitalized patients with type 2 diabetes Hospital X Pekanbaru. The type of research wasdescriptive. Data retrieved from 63 the medical records of patients with type 2 diabetes at Hospital X Pekanbaruperiod January - December 2014. The most characteristics of subject was average of age 55.40 (± 10.91) years, theaverage of RBG level 313.37 (± 135.81) mg / dL, female (55.6%), financing with BPJS (49.2%), housewives (49.2%),the diagnosis of type 2 diabetes with complications (38.1 %). The most insulin usage according to duration of actionwas short-acting insulin (46.4%), the number of daily doses was <20 IU from all type of insulin. The most combinationof different insulin types (7.9%) was long-acting insulin with rapid-acting insulin and the most combination of insulinand OHD (6.3%) was a short-acting insulin with gluconeogenesis inhibitor and premixed insulin with gluconeogenesisinhibitor.]]>
<![CDATA[Anisakis sp. dan Alergi yang Diakibatkannya ]]>
<![CDATA[Robiatul Adawiyah]]>;
<![CDATA[Esy Maryanti]]>;
<![CDATA[Forman E.Siagian]]>
<![CDATA[ Jurnal Ilmu Kedokteran Vol 8, No 1 (2014): Jurnal Ilmu Kedokteran ]]>
Publisher : <![CDATA[Fakultas Kedokteran Universitas Riau ]]>
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DOI: 10.26891/JIK.v8i1.2014.38-45
<![CDATA[Parasitic diseases were initially found in many endemic areas, but currently also found in non endemic areas.One is anisakiasis caused by Anisakis sp. Humans can be infected by this parasite by direct consumpt the organismand contact with the fish / products of food that containing this parasite.There are some points that can increase therisk of infection of this parasite, high movement of people from one area to another either temporary or permanent,the food processing especially in the case of the fish packing, the advance of transportation that enables the widespreadof marine products which contaminated and how to eat the fish which contaminated. Anisakis sp. Antigen derivedfrom the excretion-secretion products, somatic and cuticular of the parasite larvae. Good hygiene and understandingof the problem and potential risk will increase alertness and awareness of Anisakis sp.infections]]>
