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Cendana Medical Journal
Published by Universitas Nusa Cendana
ISSN : 23023007     EISSN : 27466809     DOI : https://doi.org/10.35508/cmj
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
Cendana Medical Journal (CMJ) menerima naskah dari sarjana, mahasiswa pascasarjana, residen, doktor program internship, staf fakultas kedokteran, staf rumah sakit dan pihak-pihak yang tertarik untuk menulis karya ilmiah. Artikel ilmiah yang diposting di CMJ meliputi: editorial, artikel penelitian, EBCR (Evidence Based Case Report), laporan kasus, dan ulasan. Untuk artikel penelitian sebaiknya penelitian kedokteran dasar atau biomedis.
Arjuna Subject : Kedokteran - Review dan Referensi, Kedokteran
Articles 286 Documents
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THE EFFECT OF RED BETEL LEAF EXTRACT (Piper crocatum) ON THE LIVER HISTOPATHOLOGY OF WHITE RATS (Rattus norvegicus) INDUCED BY ALLOXAN Pidu Dimu, Esther Daniella; Damanik, Efrisca Br. Meliyuita
Cendana Medical Journal Vol 13 No 2 (2025): Cendana Medical Journal
Publisher : Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/cmj.v13i2.22029

Abstract

Abstract Introduction:Diabetes mellitus is a metabolic disease characterized by hyperglycemia, which results from decreased insulin secretion, impaired insulin action, or both. This condition can lead to the formation of Reactive Oxygen Species (ROS. Red betel leaf contains saponins, flavonoids, alkaloids, and tannins, which act as antioxidants. Methods: This study was a laboratory experimental research using a true experimental design with a posttest-only control group approach. The samples were divided into five groups: negative control, positive control, treatment 1 (150 mg/kgBW), treatment 2 (250 mg/kgBW), and treatment 3 (350 mg/kgBW). Data were analyzed using the Kruskal-Wallis test followed by the Post Hoc Tukey HSD test. Results: The Kruskal-Wallis test showed a significant difference in the liver histopathology of white rats induced with alloxan after administration of red betel leaf extract, with a p-value of 0.002 (p < 0.05). Discussion: The administration of red betel leaf extract proved to have positive effect on improving liver histopathology in alloxan-induced rats, with the most effective result observed at a dose of 350 mg/kgBW, showing nearly normal liver cell structures. Conclusion: Red betel leaf extract has significant effect on the liver histopathology of alloxan-induced white rats (Rattus norvegicus), with the most effective dose being 350 mg/kgBW.
The Effect Of Red Betel Leaf Ethanol Extract (Piper Crocatum) To Histopathological Image Of Rat (Rattus Norvegicus) Pancreas Induced By Alloxan Vivaldy, Jose Mario Leonardo
Cendana Medical Journal Vol 13 No 2 (2025): Cendana Medical Journal
Publisher : Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/cmj.v13i2.22041

Abstract

Introduction: Red betel leaf has secondary metabolite compounds, namely flavonoids, alkaloids, saponins and tannins. Diabetes mellitus is a metabolic disease characterized by hyperglycemia due to decreased insulin secretion, impaired insulin action, or both which produce Reactive Oxygen Species (ROS). Red betel leaf extract is expected to reduce damage to the pancreas by inhibiting the formation of ROS by the antioxidants contained therein. Method: This research is a laboratory experimental study with a true experimental design posttest only with a control group approach. The sample was divided into 5 groups, where each group consisted of 6 rats. Necrosis and degeneration were assessed in pancreas preparations. The data were analyzed by the Kruskal-Wallis test and followed by the Post Hoc LSD test. Results: The Kruskall-Wallis test found a significant difference between administration of red betel leaf extract and histopathological features of the pancreas of necrosis rats with p = 0.000 and degeneration with p = 0.001 (p<0.05). Discussion: The administration of red betel leaf extract proved to have positive effect on improving pancreas histopathology in alloxan-induced rats. Conclusion: There was a significant difference between the histopathological features of rat pancreas (Rattus norvegicus) after being given red betel leaf extract (Piper crocatum).
Relationship Of Stress Level And Motivation Of Making Final Task In Student At Faculty Of Medicine And Veterinary Medicine Universitas Nusa Cendana Alvin, Muhammad Helmi
Cendana Medical Journal Vol 13 No 2 (2025): Cendana Medical Journal
Publisher : Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/cmj.v13i2.22049

Abstract

Background : Stress is a common thing that found in students. Compared to the general population, medical students have higher stress levels. Especially when students are working on a thesis or final task. One instrument to measure stress levels is the DASS (Depression, Axiety, Stress Scale). High stress levels might be makes negative impact on individuals. One of the effects of stress is the level of motivation, in this case, the motivation of students in preparing their thesis. The instrument used to measure the level of motivation is the MSLQ (Motivated Strategies for Learning Questionnaire). Aim : Knowing the relationship between stress levels and the motivation to write a thesis for Medical Students, Faculty of Medicine and Veterinary Medicine, University of Nusa Cendana. Method : Observational analytic research with cross-sectional method. Determining the number of samples using the Lemeshow formula obtained 53 respondents using a purposive sampling technique from a total population of 60 respondents for the 2019 class. The analysis test for the two variables used the somers'd which is non-parametric test. Result : The results of the somers'd test analysis showed p value = 0.023 and r value = -0.332 The p value indicated that there was a significant relationship between stress levels and motivation. The r value indicates that the relationship between the two is negative at a moderate level. Conclusion : There is a significant relationship between the level of stress and the level of motivation of Medical students Nusa Cendana University. Keywords: Stress level; motivation level; thesis.
PENGARUH EKSTRAK ETANOL DAUN SIRIH MERAH (Piper crocatum) TERHADAP GAMBARAN HISTOPATOLOGI OTOT JANTUNG TIKUS (Rattus norvegicus) DIINDUKSI ALOKSAN Lerrick, Riky Alberth; Damanik, Efrisca Meliyuita Br.; Amat, Anita Lidesna Shinta; Nurina, Rr. Listyawati
Cendana Medical Journal Vol 13 No 2 (2025): Cendana Medical Journal
Publisher : Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/cmj.v13i2.22056

Abstract

Introduction: Red betel leaves (Piper crocatum) contain flavonoids, alkaloids, saponins, and tannins, which have antidiabetic properties. Diabetes mellitus (DM) is a metabolic disorder characterized by hyperglycemia due to impaired insulin secretion or action, leading to increased production of Reactive Oxygen Species (ROS). The antioxidants in red betel leaf extract are expected to reduce ROS formation and protect cardiac muscle from DM-induced damage.. Methods: This laboratory experimental study used a true experimental post-test only control group design. Thirty rats were divided into five groups: positive control (KK+), negative control (KK−), and treatment groups (KP1, KP2, KP3), each consisting of six rats. Histopathological features of cardiac muscle, including interstitial fibrosis, ventricular myocyte hypertrophy, and intramyocyte lipid deposits, were assessed. Data were analyzed using the Kruskal-Wallis test and Post Hoc LSD. Results: There was a significant difference in ventricular myocyte hypertrophy between groups (p = 0.009), but no significant differences were observed in interstitial fibrosis (p = 1.000) and intramyocyte lipid deposits (p = 0.866). Discussion: Red betel leaf extract at 150 mg/kg body weight effectively reduced ventricular myocyte hypertrophy in diabetic rats Conclusion: Red betel leaf extract significantly reduced ventricular myocyte hypertrophy but had no effect on fibrosis or intramyocyte lipid deposits.
Correlation Between The Level Of Knowledge Of The Family Heads Regarding Dengue Hemorrhagic Fever Risks With 3m Plus Prevention Efforts In The Working Area Of Oesapa Public Health Center Bulo, Hana Ivena; Koamesah, S. M. J.; Dedy, Maria Agnes Etty
Cendana Medical Journal Vol 13 No 2 (2025): Cendana Medical Journal
Publisher : Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/cmj.v13i2.22069

Abstract

Dengue Hemorrhagic Fever (DHF) is a tropical infectious disease caused by the dengue virus, which is transmitted by the Aedes aegypti mosquito and often leads to outbreaks. One of the key efforts to prevent DHF is through the implementation of the 3M Plus strategy. A critical factor influencing the effectiveness of 3M Plus prevention efforts is the level of public knowledge regarding the dangers of DHF. Knowledge serves as a foundation for community-based prevention, starting from the most basic social unit—the family. As the primary decision-maker, the head of the family is considered important in possessing adequate knowledge about DHF prevention to protect their family members from infection. This study aims to examine the relationship between the knowledge level of family heads regarding the dangers of DHF and the implementation of the 3M Plus prevention strategy in the working area of the Oesapa Community Health Center. This research used an analytical survey method with a cross-sectional design. The study population included all family heads in the Oesapa Health Center's working area. Samples were selected using systematic random sampling, resulting in a total of 100 respondents. Statistical analysis was conducted using the Chi-Square test via SPSS software. The results showed that most family heads had good knowledge about the dangers of DHF, and there was a significant relationship between their knowledge level and the implementation of the 3M Plus prevention strategy in the Oesapa Health Center working area (p ≤ 0.05).
Percutaneous Nephrolithotomy For Staghorn Stones: A Minimally Invasive Approach In A Region With Elevated Kidney Stone Risk Putera, Dewa Gede Agung Sasmara; Ariandy, Zaky; Telussa, Arley Sadra
Cendana Medical Journal Vol 13 No 2 (2025): Cendana Medical Journal
Publisher : Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/cmj.v13i2.22406

Abstract

A 41-year-old male with a 2-month history of left-sided abdominal pain and renal stones was treated at Prof. W. Z. Johannes Hospital, East Nusa Tenggara, Indonesia. The patients’ primary drinking water sources were rivers and refillable bottles, which elevated the risk of kidney stones. Plain radiography and MSCT imaging revealed a 5 cm x 3.5 cm staghorn stone in the left kidney. Percutaneous nephrolithotomy (PCNL) was performed in the supine position using the C-arm. A nephroscope was inserted through a small incision to visualize and extract the stone. Post-extraction, C-arm imaging assessed the kidney, and a nephrostomy tube was placed for drainage. Staghorn stones are large, branched stones that occupy much of the renal pelvis or calyces. The European Association of Urology (EAU) recommends PCNL as the first-line treatment for staghorn stones due to its high efficacy and low morbidity. PCNL, a minimally invasive approach, offers high stone-free rates, up to 95%, making it effective for stones over 20 mm. The patient's successful outcome highlights the efficacy of PCNL in managing staghorn stones, especially in areas with a high risk of kidney stones due to poor water quality. Early diagnosis and treatment avert severe complications such as recurrent infections and urosepsis.
Efektivitas Metode Peer Teaching dalam Pelatihan Psychological First Aid terhadap Peningkatan Prosocial Behavior Intention Mahasiswa Universitas Nusa Cendana Sia, Irmanuwela; Handoyo, Nicholas Edwin; Indriarini, Desi; Wijaya, R. Pasifikus Christa
Cendana Medical Journal Vol 13 No 2 (2025): Cendana Medical Journal
Publisher : Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/cmj.v13i2.23351

Abstract

Abstract Prosocial behavior, such as helping others, plays a crucial role in supporting mental health, especially among college students who often face psychological challenges and require social support. Psychological First Aid (PFA) is one form of psychosocial support that peers can provide, and peer teaching—where students teach fellow students—is considered an effective method to foster prosocial behavior intentions while enhancing mutual support. This study aimed to evaluate the effectiveness of the peer teaching method in PFA training to increase prosocial behavior intention among students at Nusa Cendana University. A quasi-experimental design with a pre-test–post-test control group was used, involving 88 students grouped through cluster sampling into experimental group I (n=3), experimental group II (n=22), and a control group (n=63). Data were collected online using the Prosocial Tendencies Measure questionnaire and analyzed with repeated measures ANOVA. The results showed no significant differences in pre- and post-test scores across the groups (p-value within subjects = 0.360; between subjects = 0.632). These findings indicate that PFA training using the peer teaching method did not significantly improve prosocial behavior intention. It is recommended that future training incorporate practical field experiences with organizations such as hospitals or disaster response agencies to improve real-world impact.
The The Correlation of Personal Hygiene Behavior on The Incidence of Dandruff (Pityriasis sicca) in Adolescents Living in Orphanages in Kelapa Lima Sub-District, Kupang City ., Veronica; Koamesah, Sangguana Marthen Jacobus; Hutasoit, Regina Marvina; Folamauk, Conrad Liab Hendricson
Cendana Medical Journal Vol 13 No 1 (2025): Cendana Medical Journal
Publisher : Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/cmj.v13i1.23565

Abstract

Background: Dandruff is a condition of exfoliation of the corneum layer of the scalp forming white flakes, which is most common in adolescents because the sebaceous glands actively produce sebum causing increased colonization of Malassezia sp. yeast, the cause of dandruff. A factor that influences the incidence of dandruff is personal hygiene behavior. Adolescents in orphanages have a high risk of experiencing dandruff due to poor personal hygiene behavior, one of which is the use of personal items alternating to fellow friends. Objective: To determine whether there is a correlation between personal hygiene behavior and the incidence of dandruff (Pityriasis sicca) in adolescents living in orphanages in Kelapa Lima Sub-District, Kupang City. Methods: This study used an observational analytic research design with a cross-sectional study design. Respondents were selected by purposive sampling method according to the inclusion and exclusion criteria by taking the minimum number of respondents using the Lemeshow formula so that 55 respondents were obtained. Data collection using personal hygiene behavior questionnaire and wood lamp inspection. Data analysis using the fisher exact test. Results: The correlation between personal hygiene behavior and the incidence of dandruff obtained p-value = 0.223 (p>0.05) with fisher exact test, so it does not have a significant correlation. Two items of personal hygiene behavior on the questionnaire, namely the use of sleeping pillows alone / changing with others has a p-value = 0.007 (p < 0.05), and shampooing after completing outdoor activities and long-term exposure to polluting dust has a p-value = 0.016, so it has a significant correlation with the incidence of dandruff. Conclusion: There is no significant correlation between personal hygiene behavior and the incidence of dandruff in adolescents living in orphanages in Kelapa Lima District, Kupang City.
The Relationship Between Stress Levels With The Incidence Of Hypertension In The Elderly At Budi Agung Social Institution, Kupang City Laly, Thamara Novelia; M.Biomed., Sp.An-TI, dr. I Made Artawan; M.Sc, dr. Derri Riskiyanti Tallo Manafe
Cendana Medical Journal Vol 13 No 1 (2025): Cendana Medical Journal
Publisher : Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/cmj.v13i1.25169

Abstract

Background : Hypertension is called the "silent killer" and the leading cause of premature death worldwide. Hypertension causes high morbidity and mortality. Stress is one of the triggering factors for hypertension due to the activity of the sympathetic nervous system which results in an intermittent rise in blood pressure. Objective : This study aims to determine the relationship between stress levels and the incidence of hypertension in the elderly at the Budi Agung Social Institution, Kupang City. Method : This study is an analytic observational study using a cross-sectional design. The research population is the elderly at the Budi Agung Social Institution, Kupang City. Sampling using probability sampling technique and obtained as many as 40 research respondents. Stress levels were measured using a questionnaire DASS (Depression Anxiety Stress Scale) 14. Blood pressure was measured using a sphygmomanometer. Result : There are 15 respondents (37.5%) experiencing severe stress levels, as many as 13 respondents (32.5%) experiencing moderate stress, as many as 10 respondents (25.0%) experiencing mild stress, and as many as 2 respondents (5.0%) classified as not stressed or normal. In hypertension, there were 24 respondents (60.0%) with stage 2 hypertension, 12 respondents (30.0%) with stage 1 hypertension, 4 (10.0%) respondents with prehypertension, and none of the respondents had normal blood pressure or no hypertension. The results of the bivariate analysis using the spearmen rank test obtained p=0.001 (r=0.494). Conclutions : There is a relationship between stress levels and the incidence of hypertension in the elderly at the Budi Agung Social Institution, Kupang City Keywords : Stress Levels, Hypertension, Elderly, Budi Agung Social Institution, Kupang City
Effect of Resistance Training with the Push, Pull, and Leg Method on Increasing the Volume Oxygen Maximal Uptake (VO2 Max) Suryanta, Andrie; Rante, Sp.OT (K), dr. Su Djie; Manafe, M.Sc, dr. Derri R. Tallo; Hutasoit, M.Kes, dr. Regina M.
Cendana Medical Journal Vol 13 No 2 (2025): Cendana Medical Journal
Publisher : Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/cmj.v13i2.27119

Abstract

Over the past three decades there have been many studies that have shown that low levels of cardiorespiratory fitness are associated with an increased risk of cardiovascular and all-cause mortality. One way to improve cardiorespiratory fitness is to increase exercise, where resistance training is one of the exercises that can be done. The best way to measure cardiorespiratory fitness is by measuring the value of (VO2 max). To determine the effect of resistance training on increasing VO2 max. The type of research conducted was quasi experimental with a pretest and posttest non equivalent design approach. The research was conducted on students of the Seminar Biara Hati Kudus with 40 respondents, who were divided into two groups, namely the treatment and control groups. There was a significant increase in VO2 max value with p=0.000 in the treatment group. However, there was no significant increase with a value of p=0.249 in the control group. There were also significant results when comparing posttest values between the treatment and control groups with a value of p = 0.036. Resistance training with the push, pull, and leg method three times a week for three weeks can affect the increase in VO2 max.

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