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Cendana Medical Journal
Published by Universitas Nusa Cendana
ISSN : 23023007     EISSN : 27466809     DOI : https://doi.org/10.35508/cmj
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
Cendana Medical Journal (CMJ) menerima naskah dari sarjana, mahasiswa pascasarjana, residen, doktor program internship, staf fakultas kedokteran, staf rumah sakit dan pihak-pihak yang tertarik untuk menulis karya ilmiah. Artikel ilmiah yang diposting di CMJ meliputi: editorial, artikel penelitian, EBCR (Evidence Based Case Report), laporan kasus, dan ulasan. Untuk artikel penelitian sebaiknya penelitian kedokteran dasar atau biomedis.
Arjuna Subject : Kedokteran - Review dan Referensi, Kedokteran
Articles 286 Documents
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The Effectiveness of Moringa oleifera Lam Extract Lotion in Promoting Healing of Second-Degree Burns in New Zealand White Rabbits Pellokila, Nindy Bethinia; Damanik, Efrisca Meliyiuta Boru; Buntoro, Ika Febianti; Hutasoit, Regina Marvina
Cendana Medical Journal Vol 13 No 1 (2025): Cendana Medical Journal
Publisher : Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/cmj.v12i2.16024

Abstract

Abstract Background: Burns are an important health problem and are responsible for 265,000 deaths worldwide. Burn healing involves a complex set of processes that must be investigated intensively to improve outcomes, particularly healing time and scar quality. One of the plants that is often used by Indonesian people as traditional medicine is Moringa (Moringa oleifera Lam). Objective: Knowing the effectiveness of Moringa leaf extract lotion (Moringa Oleifera Lam) in accelerating the healing process of second degree burns in New Zealand White rabbits Methods: This study used a true experimental design and the post-test-only controlled group, that is, data collection was carried out after the treatment. Analysis of the test results using T-test Result: In the control group (P1) and the treatment group (P2), each consisted of 6 New Zealand White rabbits. Based on the modified Nagaoka criteria score, 6 rabbits were found in the treatment group with a score of 8 while in the control group there were 3 rabbits with a score of 5, 2 rabbits with a score of 6, and 1 with a score of 7 Conclusion: There is a significant difference between the treatment group and the control group where the p value <0.05 on the T-test Keyword : Burns;Moringa oleifera lam; New Zealand White Rabbit; lotion
Efektivitas Kompres Panas pada Lansia dengan Gejala Osteoarthritis terhadap Skala Nyeri dan Skala Fungsional di Panti Sosial Budi Agung Kota Kupang Ramadani, Tiara
Cendana Medical Journal Vol 12 No 1 (2024): Cendana Medical Journal
Publisher : Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/cmj.v12i1.16085

Abstract

Background: Osteoarthritis is the most common degenerative disease in the musculoskeletal system and is chronic. Osteoarthritis is most common in the knee, hand, and hip joints and most often affects the elderly. Objective: Knowing the effectiveness of hot compress therapy in the elderly with Osteoarthritis symptoms on the pain scale and functional. Methods: The type and design of the study was pre-experimental with one-group pretest-posttest. Researchers take measurements before treatment and then compare with after treatment. The sample amounted to 26 people and the difference test between the two groups was tested using the Wilcoxon Signed Rank Test method. Results: The majority of the pain scale before the intervention was pain and more pain (30.8%) while after the intervention was less pain (38.5%). The majority of the functional scale before the intervention was moderate (65.4%) while after the intervention was mild (84.6%). From the results of the Wilcoxon Signed Rank Test there was a significant difference with a p value <0.001 (significant p<0.05). Conclusion: Hot compresses are effective in reducing the pain scale and functional scale where there is a significant decrease in the pain scale and functional scale after the hot compress intervention twice a day for seven days.
Correlation Between Prolonged Mask Use and the Severity of Acne Vulgaris Among Medical Students at Nusa Cendana University During the COVID-19 Pandemic Tungga, Charlie Eunike Novanty; Lidia, Kartini; Dedy, Maria Agnes Etty; Oematan, Herjuni
Cendana Medical Journal Vol 13 No 1 (2025): Cendana Medical Journal
Publisher : Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/cmj.v13i1.16112

Abstract

Abstract Background: At the end of 2019, the Corona-virus Disease (COVID-19) spread through droplets and direct contact, causing a high rate of transmission so and it became a worldwide pandemic. To prevent the spread of COVID-19, health protocols are applied to the entire community, namely: wearing masks, social distancing, and washing hands. The use of masks for long durations can cause acne vulgaris or commonly known as maskne. Medical Faculty students have good knowledge so that they can carry out good Health protocols. Objective: to determine the relationship between the duration of using masks on the severity of acne vulgaris in students of the Faculty of Medicine, University of Nusa Cendana, during the COVID-19 pandemic. Methods: The research method is observational analytic using a cross-sectional design conducted on preclinical students of the Faculty of Medicine, University of Nusa Cendana through a media zoom meeting, Google form, and taking direct facial photos by researchers, then the severity of acne vulgaris is assessed by a doctor. genital skin specialist. The sampling technique is purposive sampling, with the number of respondents being 76, and using the Chi Square test. Results and discussion: From this study obtained 76 respondents. Respondents with a duration of wearing a mask <3 hours are 39 (51.3%), and respondents with a duration of wearing a mask >3 hours are 37 (48.7%). The results showed that the severity level of the acne vulgaris on students of the Faculty of Medicine Undana classified as mild are 54 people (71.1%), and moderate classification as many as 22 people (28.9%). The results of the bivariate test in this study obtained the results of p = 0.000 (p <0.05) Conclusion: There is a relationship between the duration of wearing masks and the severity of acne vulgaris in medical students at the Nusa Cendana University during the COVID-19 pandemic.
Effect of Brain Gym on the Short-Term Memory of Medical Students at the University of Nusa Cendana Hamidah, Annisa Nur; Riwu, Magdarita; Manafe, Derry Tallo; Kareri, Dyah Gita Rambu
Cendana Medical Journal Vol 12 No 1 (2024): Cendana Medical Journal
Publisher : Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/cmj.v12i1.16113

Abstract

Background: The implementation of social and physical distancing during the COVID-19 pandemic has evidently limit the exercise or physical activity which could potentially have a long-term impact on health. In addition, few groups of students find it difficult to understand online classes, especially medical students who are known to have demanding learning schedule, therefore required to have supportive cognitive functions. Cognitive function, especially short-term memory, that students required in their learning activities could be improved in various ways, one of which is by doing brain gym exercise. Object: This study aims to analyze the effect of brain gym on short-term memory of students of the Faculty of Medicine, University of Nusa Cendana. Methods: The research method used in this study is Quasi Experimental with One Group Pre-Post Test design which was conducted on 54 preclinical students of the Faculty of Medicine, University of Nusa Cendana who fulfilled the inclusion and exclusion criteria. The samples were chosen using purposive sampling technique and were divided into an intervention group and a control group. The intervention group had received brain gym 3 times per week for 2 weeks with 10-15 minutes duration for each exercise. This study uses the Digit Span Test for short-term memory measurement before and after intervention followed by analysis using Paired t-test and Independent sample t-test. Results: The increase in short-term memory scores was experienced by both groups, but the control group did not indicate a significant difference. The significant difference was only appeared in the short-term memory score of the intervention group which was represented by the results of the Paired t-test analysis with p value = 0.000 (p < 0.05), while in the control group with the same analysis test indicated p value = 0.314 (p < 0.05). Most of the respondents had high short-term memory function before and after the intervention. Conclusion: There is a significant effect of doing brain gym on short-term memory in students of the Faculty of Medicine, University of Nusa Cendana. Keywords: Brain gym; short-term memory; medical students
Molecular Docking Analysis of Anti-dengue Activity of Moringa oleifera Leaves Bioactive Compounds Riwu, Audrey Gracelia; Jannah, Insani Fitrahulil; Riwu, Katty Hendriana Priscilia; Kale, Maria Laurenci Fanny Permata; Loe, Fhady Risckhy; Asa, Halena Meldy
Cendana Medical Journal Vol 12 No 2 (2024): Cendana Medical Journal
Publisher : Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/cmj.v12i2.23665

Abstract

Background: Dengue infection is an endemic disease in various tropical regions, including Indonesia, with increasing incidence and mortality rates, and currently, no specific therapy is available. One of the potential targets for therapeutic development is the dengue virus (DENV) envelope (E) protein, which plays a crucial role in viral replication in the host. Objective: This study aimed to explore the potential of bioactive compounds from Moringa oleifera leaves as inhibitors of the E protein through an in silico approach using molecular docking methods. Methods: A total of 17 bioactive compounds from Moringa oleifera leaf extract, based on previous studies, were obtained from the PubChem database, while the target protein structure was retrieved from the Protein Data Bank (RCSB). The drug-likeness properties of the compounds were evaluated using the SwissADME web tool. Molecular docking analysis was performed using PyRx Autodock, followed by 3D visualisation and ligand–protein interaction analysis using PyMOL and Discovery Studio 2.0. Apigenin, chrysin, kaempferol, and quercetin exhibited more negative binding affinity values than the control compound Celgosivir (-6.2 kcal/mol), with respective values of -7.4, -7.3, -7.4, and -7.3 Results: kcal/mol. These compounds also shared key amino acid residues with the control at the active site of the envelope protein. Moreover, all four compounds fulfilled the five drug-likeness criteria, indicating good oral bioavailability. Conclusion: Moringa oleifera leaves show potential as candidate anti-dengue agents through inhibition of the DENV envelope protein. Keywords: Moringa oleifera, molecular docking, dengue, antiviral, envelope protein
Depression Levels Among Nursing Students: A Descriptive Study Tunggal, Deif; syahrir, Syahrir; Asa, Halena Meldy; Jannah, Insani Fitrahulil; Riwu, Audrey Gracelia
Cendana Medical Journal Vol 12 No 2 (2024): Cendana Medical Journal
Publisher : Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/cmj.v12i2.23698

Abstract

Background : Depression is one of the most common mental health disorders and a serious global concern, particularly among university students. Nursing students are highly vulnerable to depression due to academic pressure, professional expectations, and the challenges of clinical and social environments. Objective : This study aimed to assess the level of depression among nursing students at Nusantara Institute of Health Sciences as a foundation for developing targeted mental health interventions. Methods : This research employed a descriptive quantitative design with 55 participants selected using purposive sampling. The instrument used was the Indonesian-validated version of the Patient Health Questionnaire-9 (PHQ-9). Data were analyzed using SPSS version 20.0. The results showed that the majority of respondents were over 20 years old (52.7%), female (67.3%), lived in boarding houses (67.3%), and were self-motivated to pursue nursing education (76.4%). Based on PHQ-9 scoring, 49.1% of the participants experienced mild depression, 9.1% moderate depression, 3.6% moderately severe depression, and 38.2% had no signs of depression. Conclusion: These findings indicate that although most respondents had intrinsic motivation and independent living conditions, mild depressive symptoms remained prevalent. Therefore, early detection and preventive mental health interventions are essential to support academic success and future professionalism among nursing students. Keywords: Depression, Nursing Students, PHQ-9, Mental Health, Early Detection.
Applying the One Health Approach to Rabies Control in the Timor Archipelago, East Nusa Tenggara: A Literature Review on Epidemiology and Strategic Interventions Kale, Maria Laurenci Fanny Permata; Riwu, Audrey Gracelia; Simarmata, Yohanes TRMR; Wuhan, Yustinus Oswin Primajuni; Loe, Fhady Rischky
Cendana Medical Journal Vol 13 No 1 (2025): Cendana Medical Journal
Publisher : Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/cmj.v13i1.23786

Abstract

Background: Rabies remains a fatal zoonotic threat in Indonesia, particularly in East Nusa Tenggara (NTT), including Timor Island. Despite national efforts, the disease persists with rising incidence, especially in areas with high dog populations, limited vaccination coverage, and weak cross-sectoral coordination. Objective: This review aims to assess the recent epidemiological trends of rabies in Timor Island and evaluate the effectiveness of One Health implementation in controlling the outbreak. Methods: A literature review was conducted using data from 2010–2025 from sources such as WHO, FAO, Indonesian government agencies, and peer-reviewed journals. Keywords included “rabies,” “One health,” “NTT,” “Timor,” and “epidemiology.” Data were analyzed descriptively and thematically to identify gaps, risks, and strategic responses. Results: Rabies remains endemic in Timor, with more than 50,000 dog bite cases and over 80 human deaths recorded between 2023–2024. Vaccination coverage in dogs remains as low as 17.6%, and there are only 324 vaccinators for the entire province. Social and cultural factors, such as free-roaming dogs and limited public awareness, contribute significantly to transmission. Implementation of One Health remains fragmented, with low community involvement and weak surveillance integration across sectors. Conclusion: A locally adapted One health approach is urgently needed to eliminate rabies in Timor. Strengthening dog vaccination, integrating digital case reporting, engaging traditional leaders, and enforcing village-based regulations are key to effective rabies control. Keywords: Rabies, Timor Island, One health, Dog Vaccination, Community Engagement, Indonesia
Hepatitis B in Pregnant Woman Detected by Triple Elimination Screening in Public Health Centre: A Case Report Adang, Gottfrieda Patiencia Taeng-ob; Lada, Christina Olly; Mari, Maria Kurniawati; Gomangani, Yuli Clementina; Ethelbert, Ryan Arnold
Cendana Medical Journal Vol 13 No 1 (2025): Cendana Medical Journal
Publisher : Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/cmj.v13i1.23861

Abstract

Introduction: Hepatitis is an inflammation of the liver that can develop into fibrosis (scarring), cirrhosis or liver cancer. As a primary health service facility, the public health centre has an important role in handling Hepatitis B in pregnant women through the Maternal and Child Health program, including triple elimination screening and case management. Case Presentation: A 23-year-old female patient came to the public health centre for routine antenatal care examination (G1P0A0) with a gestational age of 30 weeks and 4 days. The patient had no complaints (asymptomatic), had a normoweight (20,46) body mass index, and had stable vital signs, normal systemic findings on physical examination and obstetric examination. But when a triple elimination examination was carried out by rapid diagnostic test, the result shown a reactive HBsAg. Then the patient was sent to another public health centre for further advance blood test, and the result shown that the woman was positive for hepatitis B with 2.16E08 IU/mL(log 8.33) viral load. The patient are given 1x300 mg Tenofovir disoproxil fumarate (TDF) treatment along with education by the doctor in charge for Hepatitis division to consume the drug until at least during childbirth, continued until 3 (three) month after delivery. Conclusion: Identification of pregnant women with Hepatitis B can be early detected by using the triple elimination rapid test (Hepatitis B, Syphilis, HIV) as a mandatory examination for pregnant women. Clinical symptoms for hepatitis B are vary, ranging from asymptomatic to symptomatic such as nausea, vomiting, headache, and malaise, loss of appetite, darker colour of urine, followed by jaundice that appears after 1–2 weeks. However, Hepatitis B in pregnancy is mostly asymptomatic.
Comparison Of Work Intensity With pre-prandial blood sugar level, Uric Acid, And Total Cholesterol Between staff In Nusa Cendana faculty of Medicine And Veterinary Medicine With Workers In Class IIA Prison In Kupang Salem, Alexander Shintu
Cendana Medical Journal Vol 13 No 1 (2025): Cendana Medical Journal
Publisher : Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/cmj.v13i1.14162

Abstract

Abstract Background: Diabetes mellitus, uric acid and cholesterol are part of non- communicable diseases (PTM) whose prevalence is increasing globally every year. Risk factors for Diabetes mellitus include hypertension, dyslipidemia, unhealthy diet, obesity, and lack of physical activity. In line with the risk factors for diabetes, there are similarities in the risk factors for uric acid and cholesterol, namely habits such as smoking, drinking alcohol, unhealthy diet and lack of physical activity will increase the risk. Several studies have shown that the intensity of work that uses more physical activity affects the results of pre- prandial blood sugar level (GDS), uric acid and total cholesterol. Purpose: To analyze the Comparison Of Work Intensity With pre-prandial blood sugar level, Uric Acid, And Total Cholesterol Between Nusa Cendana faculty of Medicine And Veterinary staff With Workers In Class IIA Prison In Kupang. Method: This research is an observational analytic study with a cross-sectional design which was conducted on FKKH staff at Nusa Cendana University and workers at Class IIA Kupang prison through observation, measurement, observation of the observed objects as well as interviews and structured questionnaire filling of research subjects. Pre-prandial blood sugar level, uric acid, and total cholesterol were checked for the study respondents. The number of respondents was 31 FKKH Undana employees and 31 workers at Class IIA Kupang prison, so that the total number of respondents was 62 respondents who met the inclusion and exclusion criteria. The research was analyzed using univariate, different tests and comparisons using Mann Whitney statistics with a ρ-value of 0.05 which were processed using the SPSS program. Result: The results of the comparative test statistical analysis showed that there were significant differences in the variables of pre-prandial blood sugar level (p=0.030) and total cholesterol (p=0.003) between groups of employees at FKKH Undana and workers at Class IIA Kupang prison. Meanwhile, there was no significant difference between the uric acid variable between the employee groups at FKKH Undana and workers at Class IIA Kupang prison (p=0.398). Conclusion: There were significant differences in pre-prandial blood sugar level and total cholesterol examinations, but there were no significant differences in uric acid values between FKKH staff at Nusa Cendana University and workers at Class IIA Kupang prison. Keywords: GDS, Uric Acid, Total Cholesterol, Work Intensity, FKKH Employees, Prison Workers
The Relationship of Knowledge Levels About COVID-19 With COVID-19 Prevention Behavior In Oebobo Village Community Kupang Devina, Vania Carla; Wungouw, Herman Pieter; Amat, Anita Lidesna Shinta; Minggu, Dominikus
Cendana Medical Journal Vol 13 No 1 (2025): Cendana Medical Journal
Publisher : Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/cmj.v13i1.16326

Abstract

Introduction: COVID-19 is a virus that can be transmitted from human to human (human to human transmission). This virus has spread widely in China and even to other countries. This virus can spread because of the travel history of people who have been infected with the corona virus. The increase in COVID-19 in Indonesia is also based on the lack of public knowledge about COVID-19. The existence of correct information can help people to increase their knowledge. Misinformation can make people's understanding also change. Therefore, the level of community knowledge greatly influences people's behavior. Behavior is an action that can also be interpreted as all activities carried out by someone which is the result of external stimuli that explain the knowledge they have. Community behavior in preventing COVID-19 can help reduce the increase in the incidence of COVID-19. Purpose: The purpose of this study was to determine the relationship between the level of knowledge about COVID-19 and COVID-19 prevention behavior in the community in Oebobo Village, Kupang. Methods: This type of research was an observational analytic using amethod cross sectional conducted on the people of Oebobo Village, Kupang City. . Data were obtained by filling out the Knowledge Questionnaire about COVID-19 and the COVID-19 Prevention Behavior Questionnaire by 100 respondents who met the inclusion criteria. Sampling was done by using purposive random sampling technique. The results were analyzed univariately and bivariately using thecorrelation test Spearman. Results: Data from 100 respondents showed, 64.0% had a good level of knowledge, 32.0% had a sufficient level of knowledge and 4.0% had a poor level of knowledge. For preventive behavior, 68.0% had good behavior, 32.0% had moderate behavior and none had bad behavior. The results of the bivariate analysis with the correlation test Spearman showed the results of p= 0.114 (p> 0.05) Conclusion: There is no significant relationship between the level of knowledge about COVID-19 and COVID-19 prevention behavior in the community in Oebobo Kupang Village

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