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LPPM Universitas Sari Mulia Gedung D Lantai 1 JL. Pramuka No. 02 Banjarmasin Kelurahan Pemurus Luar Kecamatan Banjarmasin Timur Kota Banjarmasin Kalimantan Selatan Indonesia
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Kota banjarmasin,
Kalimantan selatan
INDONESIA
Journal of Pharmaceutical Care and Sciences
Published by Universitas Sari Mulia
ISSN : -     EISSN : 28284828     DOI : https://doi.org/10.33859/jpcs.
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology
Journal of Pharmaceutical Care and Sciences published by the LPPM Sari Mulia UniversityPharmacy department of Sari Mulia University offers a forum for publishing the original research related to pharmaceutical science and clinical research. our focus and scope are Pharmaceutical Technology, Pharmacology & Toxicology, Drug Delivery Development, Pharmacokinetic & Biopharmaceutics, Pharmacoeconomy, Pharmacoepidemiology, Pharmacovigilance, Clinical Pharmacy, Community Pharmacy, Chemical Pharmacy, and Chemical Analysis.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 162 Documents
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A Analisis Kandungan Logam Berat Pada Krim Pemutih di Kota Banjarmasin I Ketut Gunawan Kusuma; Nur Hidayah; Tuti Alawiyah
Jurnal Pelayanan Kefarmasian dan Sains Vol 1 No 2 (2021): Journal Pharmaceutical Care and Sciences
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v2i1.66

Abstract

Background Whitening cream is a mixture of chemicals or other material which is able to whiten the skin. The presence of heavy metals such as Hg and Cd in the whitening cream products are very dangerous, because if the heavy metal ions adsorbed into tissue and organs, it will cause health problems. Objective This study aims was to find out the properties and levels of heavy metals mercuri and cadmium in the sample of the bleach cream in Banjarmasin. And to find out whether heavy metals in mercury and cadmium exceed the statute limit by the National Agency of Drug and Food Control of the Republic of Indonesia BPOM RI No. 12 tahun 2019. Method The study USES a method of analytic observation with a cross sectional design. The sample of the bleach cream used was a cream-bleach product with no license of The food and drug administration. As many as five samples of bleach cream were purchased at random in three markets that were on Banjarmasin analyzed using atomic absorption spectrophotometer. Results Research shows the highest hg concentration of metal showing on a sample of bleaching cream with a code E 0.675 µ /kg, the highest cd-metal content showing on the sample of the bleach code C 0.994 mg/kg. Conclusion: The result is under the limit set by the terms by the National Agency of Drug and Food Control of the Republic of Indonesia BPOM RI No. 12 tahun 2019. Keyword: Atomic Absorption Spectrophotometer, Heavy Metal, Whitening Cream
A Aktivitas Antioksidan Dari Infusa Kelakai (Stenochlaena palustris (Burm.F) Bedd) Ali Rakhman Hakim; Amanda Shelvia Savitri; Rina Saputri
Jurnal Pelayanan Kefarmasian dan Sains Vol 1 No 2 (2021): Journal Pharmaceutical Care and Sciences
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v2i1.69

Abstract

Background: Kelakai (Stenochlaena palustris (Burn. F) Bedd.) Is a plant originating from Kalimantan that grows on peat soil. Objective: to determine the antioxidant activity of the leaves of kelakai (Stenochlaena palustris (Burm. F) Bedd.) made by infusion. Method: This type of research is true experimental and research method with post test only control group design. Kelakai made an infusion and then tested for antioxidant activity using the DPPH method. Results: The kelakai infusion positive contains flavonoids. Kelakai infusion has a very strong antioxidant activity at a concentration of 20 ppm with an absorbance value of 0.072 and an antioxidant activity of 86.90%. Kelakai infusion has an IC50 value of 6.4035 ppm. Conclusion: kelakai infusion positive contains flavonoid compounds and has a very strong antioxidant ability with an IC50 value of 6.4035 ppm. Keywords: antioxidants, flavonoids, infusion, kelakai
S Studi Rasionalitas Penggunaan Antibiotika di RSUD DR. Murjani Sampit darini kurniawati
Jurnal Pelayanan Kefarmasian dan Sains Vol 1 No 2 (2021): Journal Pharmaceutical Care and Sciences
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v2i1.70

Abstract

Background: Antibiotics are the most widely used type of drug due to the high incidence of infection in Indonesia. From the results of the preliminary study for 3 days prospectively, as many as 44 patients who received treatment, 37 patients (87%) received antibiotic therapy. There is the use of expensive antibiotics from the 3rd generation cephalosporin group, there are 4 trade names, 2 generation cephalosporins and 1 there are 6 trade names. Expensive sulbenicin and aminoglycoside derivatives are also found, Gentamicin and Kanamycin. The relatively cheap antibiotics are chloramphenicol, tetracycline, cotrimoxazole, but various brands of these products are popular with "me too drug" being used, of course with varying prices. Government Hospital type C should refer to the use of generic drugs and refer to the national antibiotic use guidelines. Therefore, researchers want to investigate further. Objective: To study the patterns of antibiotic use at the Dr Murjani Sampit Regional Hospital before and after the Educational Information Communication on Guidelines for the Use of National Antibiotics. Method: This study used a retospective and prospective descriptive observational study with pre-research intervention to medical personnel on the Guidelines for the Use of National Antibiotics and Rational Pharmacotherapy, to paramedics on the stability and method of administering injection dosage antibiotics. This retrospective study used medical documents for patients at 3 months intervals from inpatients for Surgery, Internal Medicine, Children and Gynecology. Prospective study of inpatients at the UPF Surgery, Internal Medicine, Children, and Gynecology for 1 week. Analysis of antibiotic prescribing patterns and the rationality of using antibiotics based on the National Antibiotic Guidelines and Use references. Results: The distribution pattern of antibiotic use from a retrospective study of 447 patients, there were 260 (58.1%) patients using antibiotics. Even in obstetrics UPF, 100% of the gynecologists used antibiotics. The results of a retrospective study on the rational category and the cost of using antibiotics found the rationality of the indications and patients only reached <50% of the 4 UPFs studied. The rationality of the dosage regimen was <20% and the dose regimen <10%. Average cost of antibiotics wasted Rp. 80,374 per patient. The highest wastage was at UPF Obstetrics and Gynecology of Rp. 145,223/patient, while the lowest was in UPF Children of Rp. 40,837,-/ patient. From the prospective study, there were 260 patients, 100% used antibiotics with the rationality of the indications and the patients <50%, the rationality of the drug selection was <20%, the rationality of the dosage regimen was <10%. The average wasted cost of antibiotics which became a burden for patients was Rp. 74,793,-/patient with the highest waste at the UPF Gynecology Rp. 119,272,-/patient and the lowest in UPF Children was Rp. 34,697,-/patient. Conclusion: The pattern of antibiotic use in Dr Murjani Sampit Hospital in the 4 UPFs studied was 49.1 - 100%. There was an irrational use of antibiotics, the right indication was <43%, the right drug selection was <37.7%, the right dose regimen was <20.8%, there was a combination of antibiotic interactions <6.9% and there was a waste from the use of antibiotics Rp. 80,374,-/patient in retrospective and Rp. 74,793,-/patient in the prospective study. Keywords Rationality, Antibiotics
P Profil Penggunaan Antibiotika di Puskesmas Hantakan dan Profil DAGUSIBU Antibiotika di Desa Hantakan dan Desa Alat Rina Saputri; Ali Rakhman Hakim
Jurnal Pelayanan Kefarmasian dan Sains Vol 1 No 2 (2021): Journal Pharmaceutical Care and Sciences
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v2i1.71

Abstract

Background : The used of antibiotics in Indonesia continues to increase, but not accompanied by good knowledge regarding the used of these antibiotics so that they have a high risk of causing antibiotic resistance. Objective : Knowing the profile of the use of Antibiotics in Puskesmas Hantakan and knowing the profile of DAGUSIBU antibiotics in Hantakan and Alat Villages. Method : This type of research is descriptive research with survey methods for the last 5 months from October 2020 to February 2021. The survey was also carried out directly to the respondents of the Hantakan Village RT.01 - RT.06 and in Village Alat RT.01 - RT.04. Results : The used of antibiotics at Puskesmas Hantakan is one of the top 10 drugs that are often prescribed. The type of antibiotic that is most widely prescribed is Amoxicillin. DAGUSIBU's profile on respondents shows that the majority of respondents get antibiotics from stalls, use antibiotics to treat various diseases, take antibiotics not according to intervals, stop antibiotics if they feel that conditions have improved, and still keep antibiotics in stock and dispose of antibiotics in an inappropriate way. Conclusion : Amoxicillin is a type of antibiotic that is most widely prescribed in Puskesmas Hantakan. The use of antibiotics without a doctor's prescription in Hantakan and Alat Villages is still high. The proper management of antibiotics among respondents in the Village of Hantakan and Alat was still low.
P PENGOBATAN TERKINI DAN PROFILAKSIS PRIMER PADA TOKSOPLASMOSIS Reqgi First Trasia
Jurnal Pelayanan Kefarmasian dan Sains Vol 1 No 2 (2021): Journal Pharmaceutical Care and Sciences
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v2i1.73

Abstract

Background: Toxoplasmosis is still a health problem in the world. This parasite is found cosmopolitan in humans and animals. In Indonesia, the prevalence of positive anti-Toxoplasma gondii substances in humans ranges from 2-63%, but there are still few comprehensive studies on current treatment and prophylaxis to treat it. Objective: This article will provide an in-depth review of current treatment and primary prophylaxis in toxoplasmosis. Methods: Searching the latest literature, obtained 10 relevant journals. Results: Initial therapy Pyrimethamine 200 mg was given for 6 weeks. Maintenance therapy (suppressive, secondary prophylaxis) is given for life if immune reconstitution does not occur. Primary prophylaxis against toxoplasmic encephalitis is given to patients who are seropositive for Toxoplasma. Conclusion: Initial therapy, maintenance, and primary prophylaxis can be useful to prevent worsening of the prognosis of toxoplasmosis disease.
P POTENSI KANDUNGAN KARAMUNTING (Rhodomyrtus tomentosa) DALAM BERIKATAN DENGAN HMG-CoA REDUKTASE Kunti - Nastiti; Samsul Hadi
Jurnal Pelayanan Kefarmasian dan Sains Vol 1 No 2 (2021): Journal Pharmaceutical Care and Sciences
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v2i1.76

Abstract

Background : Hyperlipidemia is the medical term for abnormally high levels of fats (lipids) in the blood. The two types of lipids found in the blood are triglycerides and cholesterol. The enzyme that plays a role in cholesterol regulation is HMG-CoA reductase. Objective : The purpose of this study was to find the content of karamunting compounds that have stability in interactions with HMG-CoA reductase. Method : The research method is to see the probability of activity with webservices, protein-compound interactions with PLANTS, visualization with Discovery studio. Results : The results of this study have a minimum activity probability of 0.5, namely -tocopherol-quinone, naringenin, quercetin, -tocopherol A, verimol K. The docking score is at least 80% against the reference ligand, namely -tocopherol-quinone (100%), blumeatin (82%), rhodomyrtosone C (80%), tetrahydroxyflavanone (81%), -tocopherol A (86%). Conclusion: The conclusion of this study is the probability of activity of the most potent compound is -tocopherol A and the interaction stability result is -tocopherol-quinone.
A Analisis Pewarna Rhodamin B dan Pengawet Asam Benzoat dalam Saus Tomat di Kota Banjarmasin tuti alawiyah; Rahmadani Rahmadani
Jurnal Pelayanan Kefarmasian dan Sains Vol 1 No 2 (2021): Journal Pharmaceutical Care and Sciences
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v2i1.77

Abstract

Background: Tomato sauce with a red color is often misused by manufacturers by adding coloring agents that are prohibited for use in food such as Rhodamin B. Tomato sauce is also usually made by adding preservatives such as Benzoic Acid which cannot be dissociated, causing toxic effects on excessive use. Objective: to analyze the coloring ingredients and preservatives in terms of qualitative analysis and quantitative analysis in several tomato sauce products circulating in Banjarmasin City. Methods: the research method is analytical description by identifying rhodamine b compounds using Thin Layer Chromatography and UV-VIS Spectrophotometry with a wavelength of 534 nm in samples of ketchup A and B, then identification of Benzoic Acid compounds is carried out by qualitative analysis, namely color test with FeCl3 reagent, acid-base titration and UV-VIS spectrophotometric method with a wavelength of 230 nm. Results: solvent KLT method used by using butanol: ethyl acetate: ammonia solvent with a ratio of 10:4:5) The results showed that the Rf value for sample 1 and sample 2 was 0.9966 cm. The results of quantitative analysis of rhodami b using UV-VIS spectrophotometer method with a wavelength of 543 nm Regression calibration curve obtained line equation y = 0.02265 x + 0.0226 with a correlation coefficient (r) of 0.998330, average sample 5.371. Conclusion: The identification results of Rhodamin B do not meet the requirements of the Permenkes, while the results of benzoic acid still meet the SNI standards.
Evaluasi Penanganan Nyeri Haid (Dysmenorrhea) Dengan Protection Motivation Theory Tasya Haditya; Mardlatillah Mardlatillah; Farah Nur Ain; Nur Syifa; Muhammad Akhzani Fadhli
Jurnal Pelayanan Kefarmasian dan Sains Vol 2 No 2 (2022): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v2i2.80

Abstract

Background: Menstruation, known as menstruation or menstruation, is a physiological change in women that occurs periodically and is influenced by reproductive hormones, starting from menarche to menopause (Syafrudin, 2011). Abnormalities or disorders related to menstruation include premenstrual tension (tension before menstruation), mastodynia (pain in the breasts), mittelschmerz (pain during ovulation), and dysmenorrhea (pain during menstruation). Menstrual pain (dysmenorrhea) is one of the disorders that causes young women to go to the doctor for consultation and treatment. Menstrual pain or called Dysmenorrhea is pain that usually arises in adolescence, which is about 2 to 3 years after the first menstruation. Menstrual pain is a complaint that is often experienced by adolescents in the lower abdomen (Kusmiran, 2013). Menstrual pain makes women unable to carry out their normal activities and requires prescription drugs. This situation causes a decrease in the quality of life of women, for example female students who experience primary menstrual pain cannot concentrate on learning and learning motivation decreases because of the pain they feel. Objective: To see and evaluate the behavior of sufferers of menstrual pain (dysmenorrhea) in carrying out protective behavior (protection motivation theory) Methods: An evaluative study that aims to see the rationale for handling menstrual pain (dysmenorrhea) in students of the Faculty of Health, Sari Mulia University, Banjarmasin. The approach used in this research design is a cross sectional study where data is collected at a certain time. Data collection was carried out at the Faculty of Health, Sari Mulia University, Banjarmasin in April-May 2021. Results: In this project, research has been carried out on the Evaluation of Menstrual Pain Management (Dysmenorrhea) with the Protection Motivation Theory. We distributed 21 questions and got 80 respondents from various departments and semesters in the health faculty, namely 51.2% pharmacy students, 28.7% nursing students, 13.7% midwifery students and 6.3% health promotion students. The 80 respondents also consisted of 52.5% 4th semester students, 31.3% 2nd semester students, 12.5% 6th semester students and 3.7% 8th semester students. The age range of the respondents was 18-22 years old. Conclusion: Respondents make efforts to protect themselves from menstrual pain (dysmenorrhea) that is felt by doing therapy, both pharmacologically and non-pharmacologically. Respondents try to do rational treatment such as using the right dose, frequency, and proper use.
P Pengobatan Terkini Alergi, Reaksi Toksik, Dan Penyakit Akibat Artropoda Reqgi First Trasia
Jurnal Pelayanan Kefarmasian dan Sains Vol 2 No 1 (2021): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v2i1.122

Abstract

Abstract Background: The presence of erusism and lepidopterism cases in Indonesia is influenced by butterfly species, regional conditions and community habits as farmers or garden workers. In addition, the population of house dust mites depends on several factors that are still being studied. Parasitological reviews of current treatments for insect disease are still poorly understood. Purpose: This article aims to review current treatments for allergies, toxic reactions, and insect-borne diseases. Methods: Recent literature search, obtained 11 relevant articles for review. Results: Local treatment due to contact with insects can be given a solution of iodine, corticosteroids and antihistamines. In severe cases, the drug can be given orally or parenterally. Conclusion: Based on the results of the review, it can be concluded that to treat airway attacks due to mite allergy, bronchodilators and corticosteroids can be given.
I Identifikasi Kadar Formalin Pada Tahu Mentah Yang Dijual Di Pasar Tradisional Kota Banjarmasin Adinda Novita Sari; Rahmadani Rahmadani; Nur Hidayah
Jurnal Pelayanan Kefarmasian dan Sains Vol 2 No 1 (2021): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v2i1.124

Abstract

Background : Tofu is one of the most famous consumed food in local society. But there still some naughty tofu sellers that using fotmalin in their tofu, as preservative. Although they obviously know that using formalin as food preservative can cause bad impact to human body. In short term effect causes nausea, vomitting, skin irritation, shortness breath and diarrhea. Beside, in long term effect causes cancer. Purpose : To know contain of formalin levels on raw tofu in traditional markets exceed the regulation. Also to know if there is an effect of sampling locations on levels of formalin in raw tofu. Method : Cross Sectional method is used in this research. People who sell tofu in Banjarmasin traditional markets were randomly selected as samples. Formalin levels analyed by using qualitative test with color reactor and quantitative test with Spectrophotometry UV-Vis. Result : In qualitative analysis with KMnO4 and Schiff , all sample shown positive result, except Sample 1. The test of using reactor KMnO4 has negative result on Sample 1. In quantitative analysis of formalin levels on Sample 1 is 13,182 mg/L, Sample 2 is 13,813 mg/L, and Sample 3 is 16,742 mg/L. In analysis tests, shown significant impact on the different markets to formalin levels in raw tofu. The result ρ value 0,006 shown strong impact and connected to different markets location to formalin levels in raw tofu. Conclusion : Result of formalin levels analysis on raw tofu shown the formalin was found in the tofu and has different markets location effect to formalin levels in raw tofu. Keyword : Raw Tofu, Formalin, Traditional Market, Spectrophotometry UV-Vis.

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