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Conferences of Medical Sciences Dies Natalis
Published by Universitas Sriwijaya
ISSN : -     EISSN : 27467805     DOI : 10.32539
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health
Conferences of Medical Sciences Dies Natalis Faculty of Medicine Universitas Sriwijaya is national conferences of medical sciences includes basic medical sciences (anatomy, physiology, histology, microbiology, biochemistry, pharmacology, and biology of medicine) and clinical medical sciences (internal medicine, obstetric gynecology, surgery, pediatric, ophthalmology, ear nose throat, dermatovenerology, anesthesiology, neurology, radiology, pathology anatomy and pathology clinic), and also public health medicine. Conferences of Medical Sciences Dies Natalis Faculty of Medicine Universitas Sriwijaya has eISSN 2746-7805.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 104 Documents
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A COMMUNITY SEMINAR ON INTRODUCING THE EMERGENCY OF COVID-19 IN CHILDREN Indra Saputra; Silvia Triratna; Desti Handayani; Silmi Kaffah
Conferences of Medical Sciences Dies Natalis Vol. 3 No. 1 (2021): Conference of Medical Sciences Dies Natalis Faculty of Medicine Universitas Sri
Publisher : Fakultas Kedokteran Universitas Sriwijaya

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Abstract

The Covid-19 virus infection has spread rapidly worldwide, making it the first pandemic of the 21st century to have caused many deaths (more than 2 million people died). Some shreds of evidence from a range of sources suggest that the rate of Covid-19 cases in children is relatively low, commonly have asymptomatic or mild symptoms, and have low mortality rates. Data released by the Indonesian Pediatrician Association (IDAI) regarding the mortality rate of children infected with Covid-19 is 42% are infants under one year of age. In addition, there are new reports of severe and life-threatening cases of Covid-19 complication in children, which occur 4-6 weeks after infection, known as Multisystem Inflammatory Disease in Children (MIS-C). In order to control the spreading of Covid-19 infection in children, many countries considered temporarily closing the school. However, in September 2021, the Ministry of Education and Culture of Indonesia decided to reopen the school. Schools that provide face-to-face learning for students are schools located in yellow zones or moderate-risk areas. In order to reopen the school safely, the children, teachers, and parents have to obey some strict safety protocols. Even though physically reopening schools might potentially increase the transmission in the community. Due to anticipate the increase in morbidity and mortality, it is very important to increase public knowledge about the signs and symptoms of COVID-19 in children.
PREVENTION OF ENDOMETRIAL CANCER Agustria Z Saleh
Conferences of Medical Sciences Dies Natalis Vol. 3 No. 1 (2021): Conference of Medical Sciences Dies Natalis Faculty of Medicine Universitas Sri
Publisher : Fakultas Kedokteran Universitas Sriwijaya

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Abstract

Endometrial carcinoma is a malignancy originating from the epithelial cells lining the uterine cavity. 1,3 Currently, endometrial carcinoma is often found in gynecological malignancies. Endometrial carcinoma is the sixth leading cause of death from malignancy in women. In Indonesia, endometrial cancer ranks third for genital cancer after cervical (cervical) and ovarian cancer. An endometrial biopsy is done to diagnose and evaluate abnormal intrauterine bleeding, t. However, in patients who cannot undergo an endometrial biopsy because of cervical stenosis or symptoms persist despite normal biopsy results, dilatation and curettage may be performed under anesthesia. Dilatation and curettage procedures are currently the gold standard for the diagnosis of endometrial cancer.2 Microscopic examination of endometrial biopsy and endocervical curettage can usually confirm the diagnosis of endometrioid or mucinous adenocarcinoma but rarely can be associated with the initial lesion of cervical adenocarcinoma in situ or atypical hyperplasia of the endometrium. The prognosis of patients with this type is poor and has a lower survival rate than patients with type 1. In addition, in some types of type 2 endometrial adenocarcinoma found an increase in molecules that are generally found in type 1, this indicates that type 2 endometrial adenocarcinoma can occur as a worsening. from the pre-existing type 1. 4 The risk of endometrial cancer is strongly associated with family history, Therefore, screening is needed as early as possible.6
PREVENTION OF CERVICAL CANCER Patiyus Agustiansyah
Conferences of Medical Sciences Dies Natalis Vol. 3 No. 1 (2021): Conference of Medical Sciences Dies Natalis Faculty of Medicine Universitas Sri
Publisher : Fakultas Kedokteran Universitas Sriwijaya

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Abstract

Cervical cancer is the fourth most common cancer in women globally. In 2018, 570.000 women were diagnosed with cervical cancer, and 311.000 of them died from the disease.1 In Indonesia, cervical cancer is the second most common cancer. According to GLOBOCAN, there was a decrease in incidence from 17.2% to 9.2% from 2018 to 2020. This decrease has also been seen in other countries such as the United States. However, the distribution of cervical cancer varies widely among countries. WHO projected that the global burden of cervical cancer is projected to continue to increase, rising to 700 000 cases (21% increase) and 400 000 deaths (27% increase) in 2030 compared to 2018. Preventive measures become an important step to manage this situation. Preventions such as HPV vaccination, screening, and treatment of precancerous lesions have been found to be effective.
GESTATIONAL TROPHOBLASTIC DISEASE Rizal Sanif
Conferences of Medical Sciences Dies Natalis Vol. 3 No. 1 (2021): Conference of Medical Sciences Dies Natalis Faculty of Medicine Universitas Sri
Publisher : Fakultas Kedokteran Universitas Sriwijaya

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Abstract

Gestational trophoblastic disease (GTD) is a group of tumors defined by abnormal trophoblastic proliferation. GTD is divided into hydatidiform moles (contain villi) and other trophoblastic neoplasms (lack villi).1 The malignant forms of the disease are also collectively known as gestational trophoblastic tumors or neoplasia (GTN).GTN includes the invasive mole, choriocarcinoma, placental site trophoblastic tumor, and epithelioid trophoblastic tumor. Southeast Asia and Japan have the highest reported incidence estimated to be two in 1000 pregnancies. In high-income countries, the incidence of a complete mole is approximately 1–3 per 1000 pregnancies, and the incidence of a partial mole is about 3 per 1000 pregnancies. Approximately 15–20% of patients will be treated for gestational trophoblastic neoplasia after the evacuation of complete hydatidiform mole. GTD develop from abnormal proliferation of trophoblastic tissue and form botryoid arranged vesicles. Risk factors include extremes of age, ethnicity, and a prior history of an HM, suggesting a genetic basis for its etiology. GTD causes a broad spectrum of different symptoms. The most frequent clinical symptom is abnormal vaginal bleeding. Other signs include uterine enlargement more significant than expected for gestational age, absent fetal heart tones, cystic ovary enlargement, hyperemesis gravidarum, and abnormally high level of β-hCG for gestational age. Ultrasound is the gold standard in non-invasive techniques, but histological examination is necessary to reach the final diagnosis. Different treatment modalities are available for gestational trophoblastic neoplasm depending on the type and stage; these include D&C (dilation and curettage), chemotherapy, hysterectomy, or a combination of these.2 The prognostic score for GTN reported by FIGO is a score of 0–6 is the low-risk group and 7 is the high-risk group. All patients who have hydatidiform mole should be up for β-hCG surveillance and monitoring. Most relapses occur within the first year after completion of chemotherapy. A generally approved schedule of β-hCG surveillance indicates monitoring weekly for six weeks after chemotherapy followed by biweekly measurements until six months after chemotherapy. Afterward, a biannual measurement of β-hCG for five years is sufficient.1 Seeing this, the determination of the diagnosis of GTD becomes very important. With the proper diagnosis, the management of the patient will also improve.
PUBLIC SEMINAR ON COVID-19 PREVENTION AMONG FAMILY CAREGIVERS OF HEMODIALYSIS PATIENTS Zulkhair Ali; Novadian Novadian; Suprapti Suprapti; Herleni Kartika; Eddy Yuristo
Conferences of Medical Sciences Dies Natalis Vol. 3 No. 1 (2021): Conference of Medical Sciences Dies Natalis Faculty of Medicine Universitas Sri
Publisher : Fakultas Kedokteran Universitas Sriwijaya

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Abstract

Covid-19 is usually severe and represents a poor outcome, particularly in patients who have underlying co-morbidities. Among end-stage renal disease patients dependent on dialysis, covid-19 was related to increased morbidity and mortality. There is no causative therapy currently for covid-19. Thus prevention is mainly the best attempt to limit the burden of the disease. The preventive measure may depend on vaccination and public behavior in controlling the spread of the SARS-CoV-2. In the setting of the dialysis center, the patients' and caregivers' compliance with preventive measures is critical in preventing the spreading of Covid-19. The individual's knowledge and attitudes of COVID-19 are likely to influence individual adherence. Evidence suggests that an individual’s knowledge is critical in combating pandemics. Current community service was aimed to increase family caregivers of dialysis patients’ knowledge on covid-19 prevention.
CUTANEOUS MANIFESTATIONS AND TREATMENT APPROACH OF VIRAL INFECTION DURING THE PANDEMIC Inda Astri Aryani
Conferences of Medical Sciences Dies Natalis Faculty of Medicine Universitas Sriwijaya Vol. 4 No. 1 (2022): Conference of Medical Sciences Dies Natalis Faculty of Medicine Universitas Sri
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/confmednatalisunsri.v4i1.90

Abstract

Coronavirus disease-19 (COVID-19) merupakan infeksi pandemic disebabkan severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) yang tidak hanya bermanifestasi pada pulmonal namun juga ekstrapulmonal. COVID-19-associated cutaneous manifestations diklasifikasikan menjadi lima kelompok besar, dapat menjadi salah satu petunjuk diagnosis dan keparahan infeksi virus. Pendekatan terapi diberikan berdasarkan temuan klinis dan keparahan penyakit. Di era pandemik ini juga pada September 2022, Center for Disease Control and Prevention (CDC) menyatakan terjadi outbreak monkeypox di seluruh dunia.  Kasus pertama terkonfirmasi laboratorik monkeypox di Indonesia dilaporkan pada Agustus 2022. Mengenali manifestasi kulit infeksi monkeypox virus dapat membantu deteksi dini penyakit, terapi dan pencegahan untuk pencegahan penyebaran lebih lanjut.
NEW GDMT OF HEART FAILURE WITH REDUCED EJECTION FRACTION (HFrEF): THE ROLE OF DAPAGLIFLOZIN Erwin Sukandi; Amelia Farianty; Elzan Zulqad Maulana
Conferences of Medical Sciences Dies Natalis Faculty of Medicine Universitas Sriwijaya Vol. 4 No. 1 (2022): Conference of Medical Sciences Dies Natalis Faculty of Medicine Universitas Sri
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/confmednatalisunsri.v4i1.91

Abstract

Gagal jantung masih menjadi salah satu penyakit dengan angka mortalitas yang tinggi di seluruh dunia. Keterlibatan komorbiditas dan variasi etiologi dari penyakit ini merupakan salah satu tantangan bagi klinisi untuk melakukan pendekatan diagnosis serta penatalaksanaan pada gagal jantung. Klasifikasi gagal jantung itu sendiri terbagi menjadi tiga yaitu, Heart Failure with Preserved Ejection Fraction (HFpEF), Heart Failure with Mildly Reduced Ejection Fraction (HFmrEF) dan Heart Failure with Reduced Ejection Fraction (HFrEF) yang terbagi berdasarkan fungsi ejeksi fraksi. Penatalaksanaan gagal jantung selama ini mengarah kepada penghambatan jalur sistem renin angiotensin-aldosteron, neprilysin dan jalur simpatis melalui agen angiotensin-converting enzyme (ACE) inhibitors, angiotensin II receptor blockers (ARB), angiotensin receptor-neprilysin inhibitor (ARNI), beta blocker (BB) dan mineralcorticoid receptor antagonist (MRA). Ketiga pendekatan terapi pada kasus gagal jantung ini merupakan pilar dalam tatalaksana kasus gagal jantung dengan/atau tanpa komorbid lainnya. Akan tetapi, angka mortalitas pada penderita gagal jantung tetap meningkat secara global, sehingga terapi lain masih dikembangkan dalam beberapa studi. Studi terbaru menunjukkan pemberian salah satu terapi diabetes mellitus yaitu agen Sodium-dependent Glucose Transporter-2 Inhibitor (SGLT2 Inhibitor) salah satunya dapagliflozin memiliki efek positif terhadap perbaikan klinis serta pencegahan komplikasi terhadap penderita gagal jantung dengan/atau tanpa diabetes mellitus. Pada tinjauan pustaka ini akan disajikan pengunaan Dapagliflozin sebagai salah satu rekomendasi terapi terbaru pada kasus gagal jantung khususnya pada HFrEF.
INJEKSI KORTIKOSTEROID INTRATIMPANI PADA TULI MENDADAK Listya Paramita; Fiona Widyasari; Ahmad Hifni; Abla Ghanie
Conferences of Medical Sciences Dies Natalis Faculty of Medicine Universitas Sriwijaya Vol. 4 No. 1 (2022): Conference of Medical Sciences Dies Natalis Faculty of Medicine Universitas Sri
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/confmednatalisunsri.v4i1.92

Abstract

Tuli mendadak merupakan tuli sensorineural yang termasuk dalam kedaruratan neurotologi. Tuli mendadak adalah penurunan pendengaran sensorineural 30 dB atau lebih, paling sedikit tiga frekuensi berturut-turut dan berlangsung dalam waktu kurang dari 72 jam. Diagnosis tuli mendadak ditegakkan berdasarkan anamnesis, pemeriksaan fisik, pemeriksaan fungsi pendengaran dan pemeriksaan penunjang untuk mencari etiologi yang mendasari terjadinya tuli mendadak. Penatalaksaan kasus tuli mendadak sebaiknya diterapi berdasarkan etiologi yang mendasarinya. Namun hampir sebagian kasus tuli mendadak bersifat idiopatik. Salah satu terapi tuli mendadak adalah dengan pemberian kortikosteroid. Kortikosteroid dapat diberikan secara sistemik maupun injeksi intratimpani. Pemberian kortikosteroid melalui intratimpani dapat sebagai terapi awal, kombinasi dengan terapi lain atau sebagai terapi penyelamatan (salvage therapy). Injeksi kortikosteroid intratimpani dapat menjadi alternatif pada penanganan tuli mendadak, khususnya jika terapi sistemik gagal. Injeksi intratimpani juga memiliki keuntungan yaitu konsentrasi obat yang tinggi bila diberikan langsung ke telinga yang terkena atau untuk menghindari efek samping steroid sistemik dan dapat diberikan pada pasien dimana kortikosteroid sistemik kontraindikasi untuk diberikan.
PENATALAKSANAAN OTITIS MEDIA SUPURATIF KRONIK DI FASILITAS KESEHATAN PERTAMA Fiona Widyasari; Ahmad Hifni; Abla Ghanie
Conferences of Medical Sciences Dies Natalis Faculty of Medicine Universitas Sriwijaya Vol. 4 No. 1 (2022): Conference of Medical Sciences Dies Natalis Faculty of Medicine Universitas Sri
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/confmednatalisunsri.v4i1.93

Abstract

Otitis media supuratif kronik (OMSK) adalah peradangan kronis pada telinga tengah yang berlangsung lebih dari 2-6 minggu yang ditandai dengan adanya perforasi membran timpani dan keluar cairan dari telinga/otorea secara terus menerus atau hilang timbul. OMSK sering menyebabkan morbiditas dan mortalitas sehingga masih menjadi masalah kesehatan masyarakat yang utama di seluruh dunia dan merupakan penyakit telinga yang sampai saat ini masih sering dijumpai terutama di negara berkembang, termasuk di Indonesia. Diagnosis dapat ditegakkan melalui anamnesis dan  pemeriksaan fisik. Tatalaksana OMSK meliputi terapi medikamentosa disertai tindakan pembedahan. Tatalaksana medikamentosa adekuat di fasilitas Kesehatan pertama meliputi pemberian aural toilet dan antibiotika baik topikal maupun sistemik dapat mengurangi tingkat keparahan. Tindakan pembedahan pada OMSK bertujuan untuk eradikasi penyakit, menghasilkan telinga yang kering permanen, dan memperbaiki fungsi pendengaran. Komplikasi yang terjadi akibat OMSK meliputi komplikasi intrakranial dan intratemporal.
ANNOYING ACNE: WHAT SHOULD WE DO? Yuli Kurniawati; Tiar Marina Octyvani
Conferences of Medical Sciences Dies Natalis Faculty of Medicine Universitas Sriwijaya Vol. 4 No. 1 (2022): Conference of Medical Sciences Dies Natalis Faculty of Medicine Universitas Sri
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/confmednatalisunsri.v4i1.94

Abstract

Akne vulgaris (AV) adalah peradangan kronis pada unit pilosebasea, yang melibatkan 4 elemen kunci dalam patogenesis, termasuk hiperproliferasi folikel epidermis, produksi sebum, aktivitas Cutibacterium acnes, serta  respon imun inflamasi. Akne vulgaris terjadi pada 85% populasi dunia dan menimbulkan berbagai dampak negatif pada pasien. Penatalaksanaan AV tetap menjadi tantangan bagi sebagian besar klinisi, karena terdapat  beberapa faktor internal dan eksternal yang menyebabkan AV rekalsitran namun cenderung diabaikan.  Tinjauan pustaka ini bertujuan untuk memaparkan berbagai faktor yang menyebabkan AV rekalsitran sehingga  klinisi dapat mengidentifikasi tantangan ini dan menanganinya dengan tepat. Beberapa strategi untuk menangani AV rekalsitran juga diuraikan.

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