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Arman Harahap
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International Journal of Health and Pharmaceutical (IJHP)
Published by CV. Inara
ISSN : -     EISSN : 2808845X     DOI : https://doi.org/10.51601/ijhp
Core Subject : Health,
Nursing Public Health
International Journal of Health and Pharmaceutical (IJHP) e- ISSN : 2808-845X is a communication media and scientific publication in the health and pharmaceutical fields published by Inara Publisher. International Journal of Health and Pharmaceutical (IJHP) contains articles from research focusing on basic medicine, clinical medicine, epidemiology, preventive medicine (social medicine), pharmacy, and other medical fields. International Journal of Health and Pharmaceutical (IJHP) is published periodically four times a year (February, May, August and November).
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 567 Documents
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The Relationship between Characteristics of Chronic Obstructive PulmoNary Disease Patients and Spirometry Results (FEV1) in the Treatment Room of Waled Regional Hospital, September 2023-September 2024 Nadiyah Athirasaffa; Dwi Rosa Eka Agustina; Rian Damayanti
International Journal of Health and Pharmaceutical (IJHP) Vol. 6 No. 2 (2026): May 2026
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v6i2.631

Abstract

Chronic Obstructive Pulmonary Disease (COPD) is the fourth leading cause of global mortality with a high prevalence in Indonesia (3.7%), dominated by demographic factors such as advanced age and occupational exposure in rural areas such as Cirebon Regency, however, analytical studies of the relationship between patient characteristics and lung function (FEV1) are still minimal. This study aims to analyze the description and relationship of age, gender, and occupational history of COPD patients with FEV1 spirometry results. Using a cross-sectional analytical observational design on medical record data of 131 adult patients (>26 years) at Waled Regional Hospital from September 2023–September 2024 via total sampling, bivariate analysis was performed using Spearman Rank and Chi-Square tests (SPSS 26, α=0.05). The results showed that the majority of patients were elderly (>65 years, 45.04%), male (67.94%), construction workers (31.30%), and very severe (<30% FEV1, 62.60%); There was a weak positive significant association between age (p=0.040; r=0.180) and gender (p=0.045; r=0.176), but no significant association was found for occupation (p=0.450). The study concluded that demographic factors influence COPD progression, recommending routine risk-based spirometry screening to optimize prognosis in primary care settings
Article Review: Phenotypic and Genotypic Identification of Bacillus cereus in Soy Milk Ni Ketut Sastraningsih; I Putu Bayu Mayura; Ida Bagus Nyoman Putra Dwija
International Journal of Health and Pharmaceutical (IJHP) Vol. 6 No. 2 (2026): May 2026
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v6i2.633

Abstract

Bacillus cereus  is a Gram-positive, spore-forming bacterium frequently found as a contaminant in various food products, including soy milk, and is recognized as a causative agent of foodborne illnesses. Its pathogenicity mainly arises from the production of toxins such as non-hemolityc enterotoxin (nhe), hemolysin BL (hbl), and cytotoxin K (cytK), which contribute to gastrointestinal disorders. Conventional phenotypic identification methods, including culture, morphological observation, and biochemical assays, are simple but often lack specificity in distinguishing B. cereus from the B. cereus group. Therefore, genotypic approaches based on molecular techniques such as PCR and Whole Genome Sequencing (WGS) are required to achieve higher sensitivity and precision. The gyrB gene serves as a molecular marker for species confirmation, while the nhe gene complex acts as a virulence determinant in identifying toxigenic strains. The integration of phenotypic and genotypic methods provides a more comprehensive understanding of B. cereus contamination in soymilk, elucidating its genetic diversity and pathogenic potential, which are essential aspects of food safety assessment.
Biofilm: a Virulent Form of Bacteria Life In Which Leads an Emerging Battleground of Antibiotic Resistance I Putu Bayu Mayura; Putu Yuliandari
International Journal of Health and Pharmaceutical (IJHP) Vol. 6 No. 2 (2026): May 2026
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v6i2.634

Abstract

Biofilms represent a highly virulent bacterial lifestyle that substantially contributes to the global escalation of antimicrobial resistance by protecting pathogens from conventional therapies. This study aimed to synthesize current evidence on biofilm structure, developmental stages, and mechanisms underlying antibiotic recalcitrance in clinically important bacteria, including Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus. A systematic qualitative literature review was conducted using peer-reviewed articles published between 2016 and 2022 retrieved from Google Scholar, PubMed, and related scientific databases. Approximately 20 relevant studies were purposively selected based on predefined inclusion criteria, and thematic content analysis was applied to identify recurrent resistance mechanisms. The findings showed that biofilm resilience was driven by the synergistic interaction of extracellular matrix barriers, metabolic heterogeneity, persister cells, quorum sensing regulation, altered membrane permeability, stress responses, and multidrug efflux pumps. These mechanisms enabled bacteria to exhibit both genetic resistance and phenotypic tolerance, often increasing antimicrobial survival capacity up to several thousand-fold compared with planktonic cells. The review concluded that biofilm-associated infections cannot be effectively managed through single-antibiotic approaches alone. Integrated therapeutic strategies combining antibiotics with matrix-disrupting agents, quorum sensing inhibitors, and early detection technologies are required to reduce chronic infections and healthcare-associated transmission. These findings provide a conceptual basis for developing precision anti-biofilm interventions and future translational research.
Evaluation of Information System X Users Using the HOT-Fit Method at RSUD X in 2026 Rasya Fadia Rohim; Yanto Haryanto; Bhakti Aryani; Fitria Dewi Rahmawati
International Journal of Health and Pharmaceutical (IJHP) Vol. 6 No. 2 (2026): May 2026
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v6i2.635

Abstract

Digital transformation in the healthcare sector demands optimization of the Hospital Management Information System (SIMRS), including system information X at RSUD X, which still faces technical and usability challenges. This study aims to analyze the relationship between human, organizational, and technological factors and net benefits using the HOT-Fit model. The study used a quantitative, analytical descriptive design with a cross-sectional approach. The population was 117 SIMRS users with a sample of 91 respondents using the proportionate stratified random sampling technique. The research instrument was a 38-item Likert questionnaire that had been tested for validity and reliability. Data analysis was performed univariately and bivariately using the Spearman correlation test. The results showed that all variables had a significant relationship with net benefits, with moderate strengths for human (r=0.560) and organizational (r=0.573), and strong for technology (r=0.659). In addition, most respondents gave positive assessments on all HOT-Fit dimensions, although there were still obstacles in access speed and technical services. The conclusion of this study shows that technological factors are the main determinant in increasing SIMRS benefits, supported by the role of human and organizational factors. System optimization requires infrastructure improvements, ongoing training, and consistent organizational support.
The Relations of Knowledge, Attitude, and Motivation, General Surgeons and Nurses, Toward Nosocomial Infection Prevention Practices Inside the Operating Room Muhammad Nazhim; Enrico Adhitya Rinaldi; Fresley Hutapea
International Journal of Health and Pharmaceutical (IJHP) Vol. 6 No. 2 (2026): May 2026
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v6i2.637

Abstract

This study aims to analyze the effect of knowledge, attitudes, and motivation on healthcare workers’ service performance in the context of infection prevention in operating rooms. The study employed a quantitative approach with a cross-sectional design. The population consisted of all healthcare workers involved in operational services at RSUD H. Hanafie Muara Bungo, Indonesia, using a total sampling technique with a sample size of 30 respondents. Data was collected through structured questionnaires and analyzed using Spearman correlation and linear regression. The findings indicate that knowledge does not have a significant effect on service performance, while attitudes show a significant relationship with moderate strength. Motivation emerges as the most dominant factor, exhibiting a strong and significant relationship with service performance. Simultaneously, knowledge, attitudes, and motivation significantly influence service performance, contributing 53.4% to its variance. These findings suggest that service performance is not solely determined by cognitive aspects but is strongly influenced by behavioral and motivational factors. Therefore, improving service quality requires an integrated managerial approach focusing on strengthening motivation and fostering professional attitudes, alongside enhancing workforce competencies.
The Effects of Work Motivation, Workload, Work Stress, Perceived Organizational Support, and Organizational Citizenship Behaviour on the Performance of Healthcare Workers Joseph John Rivaldo Kia Bolly; Enrico Adhitya Rinaldi; Nurcahyo Andarusito
International Journal of Health and Pharmaceutical (IJHP) Vol. 6 No. 2 (2026): May 2026
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v6i2.638

Abstract

The success of Dharmawangsa Specialized Hospital in achieving its mission to provide comprehensive mental health services greatly depends on the performance of its healthcare workers. Pre-research data indicate a negative trend in the number of healthcare workers with excellent performance, declining from 17.64% in 2022 to 9.52% in 2024. This study aims to analyses the effects of work motivation (X1), workload (X2), work stress (X3), Perceived Organizational Support (POS) (X4), and Organizational Citizenship Behaviour (OCB) (X5) on the performance of healthcare workers (Y) at Dharmawangsa specialized hospital. This study used a quantitative approach with a cross-sectional design. The accessible population consisted of all healthcare workers actively working at Dharmawangsa, totalling 42 respondents selected through total sampling. The data were analysed using the SEM-PLS method with Smart-PLS v4 software. The results of hypothesis testing showed that work motivation had a negative and insignificant effect on performance (T-statistic = 0.389; p-value = 0.697), workload had a positive and significant effect on healthcare worker performance (T-statistic = 2.189; p-value = 0.029), work stress had a positive and significant effect on healthcare worker performance (T-statistic = 2.116; p-value = 0.034), POS had a negative and insignificant effect on performance (T-statistic = 0.544; p-value = 0.587), and OCB had a positive and significant effect on healthcare worker performance (T-statistic = 2.424; p-value = 0.015). This study concludes that workload, work stress, and OCB are proven to have a significant effect on the performance of healthcare workers at Dharmawangsa Specialized Hospital Indonesia.
The Sharia Marketing Strategy in Hospitals to Meet Customer Health Needs Enrico Adhitya Rinaldi; Erlina Puspitaloka Mahadewi
International Journal of Health and Pharmaceutical (IJHP) Vol. 6 No. 2 (2026): May 2026
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v6i2.639

Abstract

The concept of sharia marketing in hospitals currently has differences with conventional marketing that invite customers to approach their Lord through health services. This new trend is not found in conventional marketing concepts. Hospitals play an important role in the development of public health, and the products or services produced are appropriate to meet customer needs, in health services that bring them closer to Allah the Creator with the maqoshid sharia approach. Customers whose needs are met will feel satisfied and their worship will be of increasing quality with better health conditions. The method in this writing is a study of sharia marketing literature by discussing marketing strategies in Islam that can be implemented in sharia and non-sharia hospitals (general hospitals) that want to apply it. Result: in several dimensions must meet the provisions of Islamic Sharia, including 1. products must be halal and have the right quantity and quality; 2. changing prices must be followed by changes in product quantity and quality and have price control; 3. Place can be interpreted as distribution and business premises should be able to create value and raise a better standard of living by providing ethical services; 4. promotional ethics avoid false and misleading advertising; 5. Marketers must be honest and responsible for the products they produce; 6. They must possess intellectual integrity and a higher level of awareness throughout the process; 7. Their physical business premises must have an Islamic architectural style; 8. They must be faithful in their promises; and 9. They must be patient in their service and communication. Decisions based on Sharia Marketing Strategies (SMS) are crucial for hospital management and marketers in carrying out their role as pioneers of Islamic outreach in hospital healthcare services.
Plain Photo Overview of Legg Calve Perthes Disease Anggita Putri Kantilaras
International Journal of Health and Pharmaceutical (IJHP) Vol. 6 No. 2 (2026): May 2026
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v6i2.644

Abstract

Legg-Calvé-Perthes disease (LCPD) is a condition affecting the hip joint in children, characterized by avascular necrosis of the femoral head due to impaired blood flow. The disease primarily affects children aged 2–8 years, with a higher incidence in males. The exact cause of the disease remains unknown, but potential factors include trauma, vascular compromise, and coagulation abnormalities. LCPD is diagnosed through clinical symptoms, physical examination, and imaging, with plain radiographs being the primary diagnostic tool. The disease progresses through four stages: ischemia, fragmentation, rheoossification, and remodeling, each with characteristic radiographic features. In the early stages, plain radiographs are often normal, which can lead to misdiagnosis. Treatment aims to prevent arthritis and deformity, with conservative approaches such as physiotherapy or surgical intervention depending on the severity and age of the patient. This review aims to provide an overview of the radiographic features and clinical stages of LCPD, emphasizing the importance of early detection for more effective management and improved outcomes.
The Efforts to Improve the Achievement of Controlled DM Patient Treatment in the Prolanis Program at Jasinga Community Health Center Enrico Adhitya Rinaldi; Erlina Puspitaloka Mahadewi; Ratna Sari; Salma Nabilah Rafifah; Lisdayanti NA Hi Nur; Vita Emilya; Azzahra Inda Latifan
International Journal of Health and Pharmaceutical (IJHP) Vol. 6 No. 2 (2026): May 2026
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v6i2.645

Abstract

The aim of this study is to prevent uncontrolled diabetes can lead to various chronic complications, such as coronary heart disease, stroke, kidney failure, neuropathy, and blindness. These conditions not only reduce the patient's quality of life but also increase morbidity and mortality rates, and healthcare costs. As a promotive and preventive effort, the Social Security Administering Agency (BPJS Kesehatan) in Indonesia, has developed the Chronic Disease Management Program (Prolanis), one of which is aimed at people with type 2 diabetes. This program is implemented in primary healthcare facilities (FKTP), including community health centers (Puskesmas), with the aim of improving patients' quality of life through continuous treatment, health education, regular physical activity, and regular clinical monitoring. Prolanis consists of six main components: medical consultations, group education, reminders via SMS gateway, home visits, club activities such as group exercise, and monitoring of patient health status. Research method of this study used a descriptive observational design with a cross-sectional approach and was conducted at the Jasinga Community Health Center from August to September 2025. The subjects were all diabetes mellitus patients registered in the Prolanis program. Result data distribution of patients at Jasinga 38,1% controlled and 61,9% uncontrolled despite these limitations, this study has important implications. From a primary healthcare perspective, Jasinga Health Center can utilize simple educational media such as pamphlets and control cards as a means of patient monitoring. However, this strategy should be complemented by additional interventions such as home visits, the establishment of digital communication groups, and increasing family participation.
Altered Level of Consciousness in Metabolic Disease: An Emphasis on the Pathomechanism of Hepatic Encephalopathy Steven Jonathan; I Ketut Suryana; I Made Suma Wirawan
International Journal of Health and Pharmaceutical (IJHP) Vol. 6 No. 2 (2026): May 2026
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v6i2.548

Abstract

The present study reports the first comprehensive study on the freshwater macroinvertebrates and its habitat preferences in Bilah River, the largest riverin the Northern Sumatra. The riverside is characterized by the presence of anthropogenic and industrial activities which may alter the macroinvertebrate assemblage and biodiversity. Five months of investigation on 10 sampling stations from December 2016 to October 2017 was conducted based on the river flow in Bilah River. Principal component analysis indicated a decrease in trophic status from upstream to downstream of the river. A total of 27 taxa were recorded, with the most abundant group were members of Odonata, Gastropoda, and Decapoda. The highest density of macroinvertebrate was observed from station 1 (160 ind m-2), while the lowest density was observed from station 9 (38.64 ind m-2). Based on species distribution and similarity, two groups of habitats may be distinctively recognized based on the Bray-curtis similarity coefficient. Group 1 consisted of station 1, 2, 3 and 4 while group 2 consisted of station 5, 6, 7, 8, 9, and 10. Based on the diversity indices as ecological parameters, the habitat condition in Bilah River is categorized from low to moderately polluted. Spatial patterns in both environmental conditions affecting the macroinvertebrate assemblage was observed using canonical correspondence analysis (CCA) revealed the preferences from each macroinvertebrate species towards environmental conditions.

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