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INDONESIA
Jurnal Sehat Indonesia (JUSINDO)
Published by Publikasi Indonesia
ISSN : 27753077     EISSN : 27750892     DOI : 10.36418
Core Subject : Health,
Dentistry Health Professions Medicine & Pharmacology Nursing Public Health Veterinary
Ruang lingkup dan fokus penelitian terkait bidang kajian dengan penekanan pada pendekatan, yang meliputi: Kesehatan Masyarakat, Kesehatan dan Keselamatan Kerja (Kesehatan Kerja; Hyperkes), Kebijakan Kesehatan (dan Analis Kesehatan), Ilmu Gizi, Epidemiologi, Teknik Kesehatan Lingkungan, Promosi Kesehatan, Asuransi Jiwa dan Ilmu Kesehatan, Kesehatan Lingkungan, Ilmu Olah Raga, Ilmu Keperawatan, Kebidanan, Administrasi Rumah Sakit, Entomologi (Kesehatan, Fitopatologi), Ilmu Biomedis, Ergonomi, Fisiologi Kerja, Fisioterapi, Analis Medis, Fisiologi (Olahraga ), Reproduksi (Biologi dan Kesehatan), Akupunktur, Rehabilitasi Medis.
Arjuna Subject : Profesi Kesehatan - Menejmen Informasi Kesehatan
Articles 411 Documents
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Treatment Strategies: A Systematic Review of The Advancements of Topical Antibiotics for Impetigo Aprillia, Ghea; Wicaksono, Ilham Setya
Jurnal Sehat Indonesia (JUSINDO) Vol. 7 No. 2 (2025): Jurnal Sehat Indonesia (JUSINDO)
Publisher : CV. Publikasi Indonesia

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Abstract

Impetigo is a highly contagious bacterial skin infection affecting primarily children aged 2–5 years but also other age groups. It is predominantly caused by Staphylococcus aureus and Streptococcus pyogenes, with occasional involvement of anaerobic bacteria. Nonbullous impetigo accounts for 70% of cases and presents with characteristic golden-yellow crusting, while bullous impetigo manifests with toxin-induced fragile bullae. Effective management is crucial to address discomfort, cosmetic issues, and prevent complications. Topical antibiotics are first-line treatments for localized infections, while systemic antibiotics are reserved for severe or widespread cases. The increasing prevalence of antibiotic resistance, especially to mupirocin and fusidic acid, highlights the importance of adopting evidence-based treatment for effective strategies. Methods: This systematic review adheres to PRISMA 2020 guidelines. Eligible studies from 2014 to 2024 were identified through databases including PubMed, Embase, and Cochrane Library using terms related to impetigo treatment and antibiotic resistance. Studies evaluating the efficacy, safety, and resistance trends of antibiotics and alternative therapies were included. Data were extracted on demographics, interventions, outcomes, and adverse effects. Results: Emerging treatments, such as ozenoxacin, have shown promising results, offering superior efficacy and safety profiles compared to traditional agents like mupirocin and fusidic acid. Ozenoxacin demonstrated faster bacterial clearance and clinical resolution with minimal resistance development. Resistance to mupirocin and fusidic acid is increasingly concerning, highlighting the need for alternative therapies. Systemic antibiotics, including cephalexin and dicloxacillin, remain crucial for severe cases, but their use requires careful monitoring to mitigate adverse effects. Discussion: Antibiotic resistance poses a significant challenge in impetigo management. Topical therapies like ozenoxacin represent effective first-line options for localized infections, while systemic antibiotics address severe cases. Public health strategies emphasizing antibiotic stewardship, hygiene education, and accessible healthcare are essential to reduce the global burden of impetigo. Research on head-to-head comparisons of newer and traditional therapies will further refine treatment guidelines. Conclusion: Advances in impetigo management, particularly the introduction of ozenoxacin, offer effective solutions for localized infections. However, antibiotic resistance trends necessitate ongoing surveillance and research to optimize treatment strategies and improve patient outcomes globally.
Hubungan Perilaku Terhadap Kejadian Computer Vision Syndrome Pada Mahasiswa Fakultas Kedokteran Universitas Muhammadiyah Semarang Putri, Feby Ananda; Martiningsih, Wahju Ratna; Kurniati, Ika Dyah
Jurnal Sehat Indonesia (JUSINDO) Vol. 7 No. 2 (2025): Jurnal Sehat Indonesia (JUSINDO)
Publisher : CV. Publikasi Indonesia

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Abstract

CVS is a physical disorder that often occurs, one of which is in the eye where there is a combination of eye complaints with a duration of more than 4 hours without any rest breaks. Computer use without rest breaks can cause several eye complaints such as headaches, back pain, blurred vision, dry eyes, the sensation of burning or burning eyes, and red eyes. The factors that influence the incidence of CVS include women who are more susceptible to CVS, sitting or lying positions, distance <40 cm, and use of contact lenses or contact lenses. COVID 2019 requires learning to be done online. The purpose of this study was to determine the factors associated with CVS in students of the Faculty of Medicine, University of Muhammadiyah Semarang. Research method: this research is observational analytic research with a cross-sectional method. This study uses a questionnaire and a lux meter as instruments or measuring devices to obtain research data. The number of samples from this study was 81 students. The test data used to process the data are Chi-Square and Rank-Spearman. . Research Results: There is a relationship between CVS and the sitting position as indicated by p 0.018. There is a relationship between the distance from the eye to the screen which is shown with a p-value of 0.004. But there is no relationship between screen brightness and CVS as indicated by the p-value of 1.000 (p>0.05). Conclusion: Factors related to CVS are sitting position and distance from using a laptop, while factors not related to CVS are screen brightness
An Exploratory Study of the Prevalence and Risk Factors of Hypercholesterolemia Among the Elderly in Kelating Village, Tabanan Regency Pramesti, AA Intan; Sidemen, Premayani; Wirawan, I Made Suma; Adi Putra, Kadek Nova; R. P, Indry Agatha
Jurnal Sehat Indonesia (JUSINDO) Vol. 7 No. 2 (2025): Jurnal Sehat Indonesia (JUSINDO)
Publisher : CV. Publikasi Indonesia

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Abstract

Hypercholesterolemia, characterized by elevated levels of LDL, triglycerides, and total cholesterol, is a common but often undetected condition among the elderly. In Indonesia, the prevalence of hypercholesterolemia in individuals aged 65–74 is reported at 38.2%. Early detection is critical to prevent severe complications. Dietary habits and physical inactivity, particularly in populations such as the Segara Santhi elderly group in Kerambitan Village, Tabanan—who have a history of pork consumption and low physical activity—may increase vulnerability to this condition. This preliminary cross-sectional study aimed to explore the prevalence and potential risk factors associated with hypercholesterolemia among elderly individuals in the Segara Santhi group. Using purposive random sampling, 30 elderly participants were selected. Fasting total blood cholesterol levels were measured after an 8-hour fast. Data were analyzed and presented descriptively and in tabular form. A total of 16 participants (51.6%) had total cholesterol levels >200 mg/dL, with a higher proportion observed in elderly women. No statistically significant associations (P>0.05) were found between hypercholesterolemia and gender, age, blood pressure, or fasting blood glucose. However, a significant relationship was identified between hypercholesterolemia and uric acid levels (P<0.05). As a preliminary study, these findings suggest a high prevalence of hypercholesterolemia in this elderly population and indicate a possible link with uric acid levels. Further research with a larger sample size is needed to validate these results and better understand associated risk factors.
The Silent Epidemic: Understanding Osteosarcopenia and Its Impact on Elderly Health Adi Kunti, Desak Putu Sukasanti; Putu Putrawan, Ida Bagus
Jurnal Sehat Indonesia (JUSINDO) Vol. 7 No. 2 (2025): Jurnal Sehat Indonesia (JUSINDO)
Publisher : CV. Publikasi Indonesia

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Abstract

The occurrence of osteoporosis and sarcopenia often increases in the elderly population, yet it frequently does not present clear complaints. Osteoporosis is characterized by low bone mass and damage to the microarchitectural structure of bone, while sarcopenia refers to the loss of muscle mass, strength, and function. When both conditions coinside, the term used is osteosarcopenia. The presence of osteosarcopenia can increase the risk of falls, which may lead to fractures. Falls have a significant impact, both on individuals—including a decline in quality of life, the need for care in nursing homes, and even death—and on society, which faces rising healthcare costs. The purpose of this writing is to raise awareness about osteosarcopenia, which often receives insufficient attention, by providing an overview of this condition. With a better understanding, it is hoped that effective preventive measures can be taken to reduce the negative impacts caused by osteosarcopenia.
The Implementation of Lean Healthcare As an Effort to Improve The Quality and Patient Satisfaction in Outpatient Services: A Case Study At Bontang Islamic Hospital Pranoto, Ary Sigit; Kadarisman, Sumeidi; Asnar, Etty Sofia Mariati
Jurnal Sehat Indonesia (JUSINDO) Vol. 7 No. 2 (2025): Jurnal Sehat Indonesia (JUSINDO)
Publisher : CV. Publikasi Indonesia

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Abstract

This study aims to identify the influence of Lean Healthcare, including service quality, cost, and delivery speed, on patient satisfaction in Rumah Sakit Islam Bontang outpatient services. The sample comprises 376 selected from 6,200 patients using the Simple Random Sampling method. This research employs a quantitative approach with descriptive and verification methods. Data were collected through questionnaires filled out by respondents, and the analysis was conducted using multiple linear regression with the assistance of SPSS software. The results indicate that service quality, cost, and delivery speed significantly affect patient satisfaction both partially and simultaneously. In conclusion, implementing Lean Healthcare has improved patient satisfaction in Rumah Sakit Islam Bontang outpatient services.
Kadar Carcinoembryonic Antigen dan CD4+ pada Pasien Kanker Paru Jenis Karsinoma Bukan Sel Kecil Sebelum dilakukan Kemoterapi Carcinoembryonic Antigen and CD4+ Levels in Patients with Non-Small Cell Carcinoma Lung Cancer Before Chemotherapy Beruat, Andry Elisa; Novisari Soeroso, Noni; Putra Tarigan, Setia; Chairani Eyanoer, Putri
Jurnal Sehat Indonesia (JUSINDO) Vol. 7 No. 2 (2025): Jurnal Sehat Indonesia (JUSINDO)
Publisher : CV. Publikasi Indonesia

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Abstract

Salah satu kanker dengan tingkat kematian tinggi adalah kanker paru-paru, yang menyumbang rata-rata 13% dari semua kasus kanker yang baru didiagnosis. Antigen karsinoembriogenik (CEA) adalah salah satu penanda yang dapat digunakan untuk penanda prognostik, prediktor kemanjuran untuk Terapi Bertarget atau kemoterapi, dan penanda kekambuhan pasca operasi dan metastasis. Kekebalan antikanker tergantung pada aktivitas dan interaksi sistem kekebalan bawaan dan adaptif. Penanda tumor adalah zat yang dapat digunakan untuk mendeteksi perubahan yang terjadi akibat kanker. Salah satu penanda tumor yang digunakan adalah antigen karsinoembriogenik (CEA). Cluster Of Differentiation 4 (CD4+) adalah sel polifungsi yang merupakan lengan kedua kekebalan sel T adaptif di sepanjang garis keturunan Cytotoxic Lymphocyte T (CTL). Sel T CD4+ berdiferensiasi menjadi salah satu dari beberapa subtipe fungsional sebagai respons terhadap sinyal yang masuk. Tujuan: Untuk menentukan nilai kadar CEA dan CD4 pada pasien dengan NSCLC. Metode: Penelitian ini merupakan studi observasional dengan pengumpulan darah pada pasien dengan NSCLC. Hasil: Sebagian besar pasien kanker paru-paru berusia 41-60 tahun (55%). Sebagian besar pasien NSCLC adalah laki-laki sebanyak 20 orang (100%). Berdasarkan jenis histologi, sebagian besar pasien NSCLC adalah kanker paru-paru tipe adenokarsinoma sebanyak 12 (60%), 7 (35%) kanker paru-paru jenis karsinoma sel skuamosa dan hanya 1 (5%) kanker paru-paru tipe karsinoma sel besar. Kadar CEA pasien NSCLC menunjukkan peningkatan kisaran abnormal 3 sampel (15%), kadar CD4+ pasien NSCLC menunjukkan peningkatan kisaran abnormal 1 sampel (5%).
Streptomyces in Mangrove Ecosystems: Ecological Roles and Biotechnological Opportunities Pambayun Faqih, Dhiajeng; Retnowati, Wiwin
Jurnal Sehat Indonesia (JUSINDO) Vol. 7 No. 2 (2025): Jurnal Sehat Indonesia (JUSINDO)
Publisher : CV. Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/.v7i2.355

Abstract

The mangrove ecosystem, a transitional zone between terrestrial and marine environments, is known for its high salinity, low pH, and limited oxygen availability, creating challenging conditions for microbial life. Among the diverse microorganisms present, Streptomyces plays a crucial role due to its ability to produce bioactive compounds, including antibiotics, anticancer agents, and antioxidants. In nutrient cycling, Streptomyces decomposes complex organic matter into simpler compounds, enhancing nutrient availability. Its role in bioremediation is also notable, with the capacity to degrade pollutants such as hydrocarbons and heavy metals, maintaining environmental quality. In agriculture, Streptomyces acts as both a biocontrol agent and a biofertilizer by producing plant hormones like Indole-3-Acetic Acid (IAA) and gibberellins, improving plant growth and resilience. Despite its potential, challenges in isolation, cultivation, and antibiotic resistance remain significant, especially in extreme environments like mangroves. However, advancements in metagenomics, co-cultivation, and bioinformatics provide innovative solutions. Metagenomics allows the discovery of previously undetectable biosynthetic genes, while co-cultivation stimulates the production of novel secondary metabolites. Bioinformatics facilitates gene function prediction and genetic engineering to optimize bioactive compound production. These technologies offer promising avenues to enhance the exploration and utilization of Streptomyces for sustainable applications in medicine, agriculture, and environmental management.
Hubungan Antara Panjang Tungkai dan Kecepatam Kontraksi Otot Tungkai dengan Daya Ledak Otot Tungkai pada Anggota UKM Bola Voli Universitas Hasanuddin Nusantara, Hebat Maha Putera; Irianto, Irianto
Jurnal Sehat Indonesia (JUSINDO) Vol. 7 No. 2 (2025): Jurnal Sehat Indonesia (JUSINDO)
Publisher : CV. Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/.v7i2.396

Abstract

Nowadays, sport has become a human need, both entertainment and a hobby for people (Lukito & Fahmi, 2020). Most of the sports that Indonesian people are interested in are game-type sports, one of which is volleyball. Volleyball is one of the most popular sports, and has even been ranked as the sport with the second most fans in the world (Damayanti et al., 2022). In volleyball, basic physical components determine the quality of movement during the game (Asnaldi, 2020). In the game of volleyball, muscle explosive power is the most substantial basic physical component, so this is the background for this research. This research aims to determine the relationship between leg length and leg muscle contraction speed and leg muscle explosive power at Hasanuddin University Volleyball UKM. This research is a quantitative study with a model using a cross sectional approach, the sampling technique used purposive sampling and obtained 36 samples that met the inclusion criteria. The results of the correlation test using the Pearson test between the independent and dependent variables showed significance (>0.05). It can be concluded that there is no relationship between leg length and leg muscle contraction speed and leg muscle explosive power in members of Hasanuddin University Volleyball UKM.
Pengobatan Herbal pada Penyakit Psoriasis dan Vitiligo Hutabarat, Rodinda; Rahmayunita, Githa
Jurnal Sehat Indonesia (JUSINDO) Vol. 7 No. 2 (2025): Jurnal Sehat Indonesia (JUSINDO)
Publisher : CV. Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/.v7i2.109

Abstract

Psoriasis dan vitiligo masih menjadi tantangan di bidang dermatologi karena bersifat kronik residif, remisi sempurna dalam terapi sulit dicapai, menyebabkan disabilitas, dan berdampak buruk terhadap kualitas hidup pasien. Karena umumnya digunakan dalam jangka waktu yang panjang, terapi untuk psoriasis dan vitiligo dapat menyebabkan beberapa masalah misalnya efek samping dan biaya pengobatan. Untuk itu terapi alternatif berupa obat herbal diharapkan dapat menjadi pilihan terapi yang efektif dengan efek samping yang lebih sedikit dan biaya yang lebih murah. Namun demikian dibutuhkan uji klinis lebih lanjut dengan penilaian keamanan dan efikasi yang lebih adekuat sebelum menggunakan obat herbal dalam praktik klinis.
Association of Vitamin D Deficiency and Diabetic Foot Ulcer Patients in Dr Mohammad Hoesin General Hospital Palembang Dahlan, Kemas; Yususf, Fahmi Jaka; Irfannuddin, Irfannuddin; Murti, Krisna; Muradi, Akhmadu; Liberty, Iche Andriyani
Jurnal Sehat Indonesia (JUSINDO) Vol. 7 No. 1 (2025): Jurnal Sehat Indonesia (JUSINDO)
Publisher : CV. Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/jsi.v7i01.149

Abstract

Vitamin D plays a role in the healing process of diabetic foot ulcers (DFU); it can improve the immune system, regulate inflammation function, and regulate growth factors in diabetes mellitus (DM). The immunomodulatory effects of vitamin D include reduced production of IL-2, IL-6, and TNF-alpha and increased production of IL-10. It also increases the activity of antimicrobial peptides (AMP) such as cathelicidin, and it promotes the differentiation of monocytes into macrophages, phagocytosis, and the production of lysosomal enzymes. Furthermore, vitamin D stimulates growth factors including vascular endothelial growth factor (VEGF) and transforming growth factor beta (TGF-β). In this study, the incidence of DM and DFU in DM patients at RSUP Dr. Mohammad Hoesin Palembang will be compared to serum vitamin D levels. This research uses quantitative methods with an analytical observational design. The Mean vitamin D serum level was 11,727 ng/mL, and there was a significant association between serum vitamin D deficiency and DFU (p-value; 0.036 < 0.05). There was a significant association between serum vitamin D deficiency and DFU occurrence (p-value; 0.036 < 0.05) in Mohammad Hoesin General Hospital Palembang. Based on the results of this study, we proposed that patients with diabetic foot ulcers should have their serum vitamin D levels checked, and that vitamin D should be given to them as part of their therapy.

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